scholarly journals “The Study of Bacteriological Agents of Chronic Suppurative Otitis Media Aerobic Culture and Antibiotic Sensitivity Testing Pattern at a Tertiary Care Hospital in and around Rajamundry: A cross-sectional study”

2021 ◽  
Vol 7 (4) ◽  
pp. 207-214
Author(s):  
Dr. Neelima Pantagada ◽  
◽  
Dr. Praveen Kavoori ◽  

Introduction: Chronic suppurative otitis media is a chronic infection of the middle ear and mastoidcavity which if not treated leads to partial or total loss of hearing and even life-threateningcomplications like meningitis and Intracranial abscess. Hence it is important to treat the persistentear discharge in CSOM according to the antimicrobial sensitivity of the organism isolated. Methods:This is a prospective cross-sectional study done in 135 clinically diagnosed patients of CSOM at GSLmedical college and General Hospital, Rajamundry, Andhra Pradesh from May 2019 to October 2019.Sterile swabs were used to collect pus from discharging ear and were inoculated onto Blood andMacConkey agar for 24-48 hrs, and identification of organisms was done by using standardbiochemical reactions and antibiotic sensitivity testing done by using modified Kirby- Bauer methodas per CLSI guidelines. Results: A total of 156 strains were isolated from 135 patients in thepresent study of which Pseudomonas aeruginosa and Staphylococcus aureus were amongst the mostisolated pathogens in culture. Imipenem showed the most sensitivity against Pseudomonas,subsequently levofloxacin and piperacillin. Linezolid was the most sensitive versus Staphylococcusensued by ciprofloxacin and cloxacillin. Conclusions: In the present study of Chronic suppurativeotitis media patients, Pseudomonas and Staphylococcus were highly prevalent and showed increasedresistance to beta-lactams and commonly used antimicrobial drugs. Antimicrobials like imipenem,piperacillin, and quinolones are effective against most cases of chronic suppurative otitis media

Author(s):  
Raj Tajamul Hussain ◽  
Sanam Altaf ◽  
Owais Makhdoomi ◽  
Mariya Ali

<p class="abstract"><strong>Background:</strong> The aim of the study was to discern the patterns in microbial diversity and the resistogram among the patients suffering from CSOM.</p><p class="abstract"><strong>Methods:</strong> A total number of 100 ear swabs were investigated for the present study. Their gram staining, direct microscopy with KOH, culture sensitivity, and biochemical tests were carried out to identify the organisms and to know their sensitivity pattern. All the swabs were collected from clinically diagnosed cases of chronic suppurative otitis media visiting otolaryngology outpatient department of tertiary care hospital. The study period was one year, from January 2016 to December 2017.  </p><p class="abstract"><strong>Results:</strong> Out of total 100 cases, 90 were culture<strong> </strong>positives, 6 showed no growth and 4 were<strong> </strong>skin contaminants (mirococci). Out of 90 culture positives, fungal culture was positive in 5 (5.5%) while combined bacteria and fungi obtained in 18 (20%) cases and only bacteria in 67 (74.4%) cases. Among the aerobic bacterial isolates, Pseudomonas aeruginosa was the most common bacteria isolated from the bacterial culture (n=36; 34.95%) followed by <em>Staphylococcus aureus </em>(n=28; 27.18%) and <em>Proteus</em> (n=13; 12.62%). Among the fungal isolates,<strong> </strong><em>Aspergillus niger </em>was predominant followed<strong> </strong>by Candida <em>albicans </em>&amp; <em>Aspergillus flavus.</em> Amikacin and imipenem were found to be the most effective antibiotics with low resistance rates.</p><p><strong>Conclusions:</strong> The present study gave an insight into the bacteriological profile of the cases of CSOM and their antibiotic sensitivity patterns. This in turn will ensure rational and judicious use of antibiotics and thus prevent emergence of resistant bugs and also the complications associated with CSOM.</p>


2020 ◽  
Vol 134 (10) ◽  
pp. 867-871
Author(s):  
C K Pedersen ◽  
P Zimani ◽  
M Frendø ◽  
N J Spindler ◽  
C Chidziva ◽  
...  

AbstractObjectiveChronic suppurative otitis media is a major cause of disabling childhood hearing loss, especially in low-income countries. Estimates on its prevalence in sub-Saharan Africa range from the lowest to the highest in the world (less than one per cent to more than five per cent). However, the prevalence of chronic suppurative otitis media in Zimbabwe is largely unknown. This study aimed to determine the prevalence of paediatric chronic suppurative otitis media and other middle-ear pathology in rural Zimbabwe.MethodA cross-sectional study was performed in primary school children aged 4–13 years from the rural province of Mashonaland East. Participants underwent video otoscopy and tympanometry.ResultsOut of 451 examined children, two (0.4 per cent) had chronic suppurative otitis media. Acute otitis media was present in one (0.2 per cent), otitis media with effusion was present in five (1.1 per cent) and scarring was present in 69 (15.3 per cent).ConclusionChronic suppurative otitis media and otitis media sequelae were surprisingly uncommon in this sample of rural primary school children in Zimbabwe. More studies, preferably population-based, are needed to enable more precise estimates of chronic suppurative otitis media prevalence in Zimbabwe.


2019 ◽  
Vol 35 (2) ◽  
Author(s):  
Shafaque Mehboob Khan ◽  
Tariq Rafi ◽  
Naveed Ahmed ◽  
Mehjabeen Mehjabeen

Objective: To study the correlation of hearing loss with depression, anxiety and stress in patients suffering from chronic suppurative otitis media in local population of Pakistan. Methods: This is a cross-sectional study conducted from May to September 2018 at tertiary care hospital of Karachi. One hundred and twenty patients of chronic suppurative otitis media were divided into three groups: Group-1 (maintained on ciprofloxacin), Group-2 (maintained on co-amoxicillin) and Group-3 (did not subject to the treatment).The measurement of hearing loss was carried out by pure tone audiometry (PTA) and the depression, anxiety and stress were scored taking depression, anxiety and stress scale (DASS) as tool. To observe the effect of hearing loss on different groups one way ANOVA was applied and Spearman correlation was used to find correlation of depression with hearing loss. Results: There was no significant difference found for hearing loss and severity among the groups treated with ciprofloxacin, co-amoxicillin and not maintained on antibiotic therapy. Positive correlations found between hearing loss and depression, anxiety and stress in patients of the three groups. Conclusion: Depression induced by hearing loss as a result of CSOM in patients need to be monitored during and after treatment and scored so that can be treated by counseling and antidepressant (if required). Information regarding this topic on population of Pakistan will be helpful for health care takers and policy makers to manage mental stress with hearing loss in CSOM. How to cite this:Mehboob S, Rafi SMT, Ahmed N, Mehjabeen. Association of hearing loss with depression, anxiety and stress in patients suffering from Chronic Suppurative Otitis Media. Pak J Med Sci. 2019;35(2):---------. doi: https://doi.org/10.12669/pjms.35.2.152 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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