scholarly journals A clinicoepidemiological study of sexually transmitted infections among men who have sex with men from a tertiary care centre in South India

Author(s):  
V. G. Binesh ◽  
A. Sarin ◽  
Betsy Ambooken ◽  
S. Suprakasan ◽  
T. P. Rakesh

<p class="abstract"><strong>Background:</strong> The prevalence of men who have sex with men (MSM) is showing an increasing trend in general population. MSM being a high risk population are more prone to develop sexually transmitted infections (STIs)<span lang="EN-IN">.</span></p><p class="abstract"><strong>Methods:</strong> With the help of Sevana, a nongovernmental organization (NGO), we were able to mobilize 81 MSM for detailed evaluation. All  MSM, after an informed consent were given a behavioural questionnaire, followed by detailed history taking, clinical examination, pre-test counselling and specimen collection.<strong></strong></p><p class="abstract"><strong>Results:</strong> All of them were clinically asymptomatic. Of the total 81 MSM in our study, 27(33.3%) had STIs as evidenced by laboratory investigations. Out of these, 3 (3.7%) had multiple STIs. The most common STI in our study group was asymptomatic herpes gentalis (12.4%), followed by latent syphilis (9.9%) and non gonococcal urethritis (8.6%)<span lang="EN-IN">. </span></p><p class="abstract"><strong>Conclusions:</strong> The high incidence of asymptomatic STIs among MSMs in our study points to the need for strengthening targeted intervention including condom usage and a compulsory medical check-up and serological screening at least once in six months for early detection and treatment of STIs. This in turn would help us in preventing the transmission of STIs including HIV<span lang="EN-IN">.</span></p>

Author(s):  
Prabahar P. ◽  
Ranganathan T. ◽  
Vijayabhaskar C. ◽  
S. Kalaivani ◽  
Balamurugan L. ◽  
...  

Background: Men who have sex with Men (MSM) have a higher prevalence of HIV and other sexually transmitted infections (STI) than the heterosexual men. In India, NACP recommendations to reduce HIV prevalence among MSM include early detection of HIV and other STI by screening and treatment. We conducted a study of STIs among MSM attending our OPD. The aim of the study was to assess the prevalence of STIs in MSM attending our OPD.Methods: 1215 MSM among 9008 patients who attended our OPD between June 2015 and May 2016 were included in the study. Detailed history was taken and clinical examination carried out. Urethral discharge and urine samples were tested for Gonococcal infection. Smears from ulcers were tested for Syphilis, Chancroid, Herpes and Donovanosis. Serum samples were tested for HIV and other STIs like Syphilis and Herpes.Results: Among 1215 MSMs, 55 (4.5%) tested positive for VDRL and TPHA and 33 (2.7%) tested positive for HIV. 24 (2%) had urethritis (10 GU and 14 NGU), 15 (1.25%) had Balanophosthitis, 12 (1%) had genital herpes, 9 (0.75%) had genital scabies, 6 (0.5%) had Genital Wart and 2 (0.16%) had Molluscum contagiosum. Prevalence of these STIs were far higher in MSMs than in heterosexual men.Conclusions: This study highlights the higher prevalence of STIs among MSMs and the need for early intervention and treatment in this high-risk population.


Author(s):  
Murugan Swamiappan ◽  
Manjula Jagannathan ◽  
Aysha Abdulla

<p class="abstract"><strong>Background:</strong> In India the estimated men who have sex with men (MSM) population is around 352, 000, among that 4.3% are living with HIV. The incidence of sexually transmitted infections (STIs) in MSM is greater than that reported in women and men who have sex with women only. The aim of the study is to determine the trends of sexual behaviour and the pattern of sexually transmitted infections in men who have sex with men.</p><p class="abstract"><strong>Methods:</strong> A retrospective study of the data collected from the clinical records of all MSM, who had attended the STI clinic of Kilpauk Medical College, Chennai, Tamil Nadu, during the three-year study period, from July 2016 to June 2019. Demographic data, sexual risk behaviour, condom usage and STIs, among the MSM, were computed and analyzed.<strong></strong></p><p class="abstract"><strong>Results:</strong> During the study period 489 MSM attended the STI clinic, 51.9% were bisexual and 48.1 % were homosexual. Among them, exclusive penetrative sex in 50.7%, exclusive receptive sex in 15.7% and both in 33.6% were reported. Condom usage was consistent in 18.8%, inconsistent in 28.8% and 52.9% never used condom. Unprotected sex is more common in oral sex than with anal sex. STIs were seen in 20.9% and HIV in 1.4% of MSM. Syphilis was the most common STI seen.</p><p class="abstract"><strong>Conclusions:</strong> Our study elucidated the high prevalence of STIs among MSM and increasing trends of sexual risk behaviour. Health service providers must take necessary steps to improve the provision of biological and medical measures to screen, treat and prevent infections.</p><p class="abstract"> </p>


2012 ◽  
Vol 9 (2) ◽  
pp. 44-48 ◽  
Author(s):  
D Karn ◽  
A Amatya ◽  
E R Aryal ◽  
S KC ◽  
M Timalsina

Background The burden of sexually transmitted infections is huge and is disproportionately affecting developing nations. In Nepal, recent available data on sexually transmitted infections are mostly targeted to high risk population. A prevalence study was thus done to explore the pattern of sexually transmitted infection syndromes among general population of Nepal. Objectives To highlight the prevalence and changing pattern of sexually transmitted infections among general population. Methods A retrospective study. The study was conducted among 145 patients attending Department of Dermatology and Venerology, Dhulikhel Hospital Kathmandu University Hospital, for voluntary counseling and testing from April 2010 to April 2011. Syndromic case management approach was used for the classification and treatment of the patients. Results 106 patients were suffering from Sexually Transmitted Infections and 2 patients were positive for Human Immunodeficiency Virus. The most common diagnosis was genital viral infections (41.7%). Prevalence was highest among drivers/conductors (26.9%) and migrating workers (23.1%). Age group 20 to 24 years was the maximum sufferers (37%). Unsafe sexual activity (66.7%) was the most potential exposure and majority of the patients were not consistent in using condom. Conclusions Genital viral infections constitute the major bulk of sexually transmitted infections. Majority of the patients suffering from sexually transmitted infections were in the age group 20 to 24 years and were mostly drivers, conductors or migrating workers by occupation. In the background of few available baseline data, the results are expected to assist successful target interventions in the near future.DOI: http://dx.doi.org/10.3126/kumj.v9i2.6287  Kathmandu Univ Med J 2011;9(2):44-8


Antibiotics ◽  
2021 ◽  
Vol 10 (8) ◽  
pp. 929
Author(s):  
Andreas Hahn ◽  
Hagen Frickmann ◽  
Ulrike Loderstädt

Prescribed antibiotic treatments which do not match the therapeutic requirements of potentially co-existing undetected sexually transmitted infections (STIs) can facilitate the selection of antibiotic-drug-resistant clones. To reduce this risk, this modelling assessed the potential applicability of reliable rapid molecular test assays targeting bacterial STI prior to the prescription of antibiotic drugs. The modelling was based on the prevalence of three bacterial STIs in German heterosexual and men-having-sex-with-men (MSM) populations, as well as on reported test characteristics of respective assays. In the case of the application of rapid molecular STI assays for screening, the numbers needed to test in order to correctly identify any of the included bacterial STIs ranged from 103 to 104 for the heterosexual population and from 5 to 14 for the MSM population. The number needed to harm—defined as getting a false negative result for any of the STIs and a false positive signal for another one, potentially leading to an even more inappropriate adaptation of antibiotic therapy than without any STI screening—was at least 208,995 for the heterosexuals and 16,977 for the MSM. Therefore, the screening approach may indeed be suitable to avoid unnecessary selective pressure on bacterial causes of sexually transmitted infections.


2006 ◽  
Vol 17 (3) ◽  
pp. 157-166 ◽  
Author(s):  
Somesh Gupta ◽  
C Ajith ◽  
Amrinder J Kanwar ◽  
Virendra N Sehgal ◽  
Bhushan Kumar ◽  
...  

Genital elephantiasis is an important medical problem in the tropics. It usually affects young and productive age group, and is associated with physical disability and extreme mental anguish. The majority of cases are due to filariasis; however, a small but significant proportion of patients develop genital elephantiasis due to bacterial sexually transmitted infections (STIs), mainly lymphogranuloma venereum (LGV) and donovanosis. STI-related genital elephantiasis should be differentiated from elephantiasis due to other causes, including filariasis, tuberculosis, haematological malignancies, iatrogenic, or dermatological diseases. Laboratory investigations like microscopy of tissue smear and nucleic acid amplification test for donovanosis, and serology and polymerase chain reaction for LGV may help in the diagnosis, but in endemic areas, in the absence of laboratory facilities, diagnosis largely depends on clinical characteristics. The causative agent of LGV, Chlamydia trachomatis serovar L1–L3, is a lymphotropic organism which leads to the development of thrombolymphangitis and perilymphangitis, and lymphadenitis. Long-standing oedema, fibrosis and lymphogranulomatous infiltration result in the final picture of elephantiasis. Elephantiasis in donovanosis is mainly due to constriction of the lymphatics which are trapped in the chronic granulomatous inflammatory response generated by the causative agent, Calymmatobacterium (Klebsiella) granulomatis. The LGV-associated genital elephantiasis should be treated with a prolonged course of doxycycline given orally, while donovanosis should be treated with azithromycin or trimethoprim-sulphamethoxazole combination given for a minimum of three weeks. Genital elephantiasis is not completely reversible with medical therapy alone and often needs to be reduced surgically.


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