scholarly journals Topical steroid abuse on face: a prospective study from a tertiary care centre of north India

Author(s):  
Asha Nyati ◽  
Anil Kumar Singhal ◽  
Devendra Yadav ◽  
Manoj Kumar Sharma

<p class="abstract"><strong>Background:</strong> Topical corticosteroids (TCS) are widely misused on face which is associated with significant adverse effects and poor awareness of these effects. The aim of this study was to assess the frequency of misuse of topical corticosteroids, the causes behind it and the most common adverse events resulting from it and to make aware the people about it</p><p class="abstract"><strong>Methods:</strong> This study was conducted at Dermatology Department of Govt. Medical College, Kota during period of one year from July 2015 to June 2016. A total of 670 patients using topical steroids over face were enrolled in the study. Details about the usage of topical corticosteroids and their side effects were recorded.<strong></strong></p><p class="abstract"><strong>Results:</strong> Majority of the patients were females (72.68%). The most common reason for misuse was melasma (57. 91%) followed by use as a fairness cream (22.38%). Most of the patient used topical steroid cream for duration of 3-6 months (33.13%). Most common age group was 21-30 years (48.20%). Acne form eruption (38.05%) and rebound erythema (28.20%) were the most common adverse effects noted. Patients were ignorant of the ingredients and their side effects.</p><p class="Default"><strong>Conclusions:</strong> Steroids have been misused by patients on their own or by pharmacist and non-dermatologist physicians for various reasons. Topical steroid should not be used on the face unless it is under strict dermatological supervision. </p>

2021 ◽  
pp. 65-66
Author(s):  
(Lt Col) Rajnish Kumar ◽  
(Lt Col) Vaka Raja Sekhar Reddy ◽  
(Lt Col) Sumit Kumar Singh ◽  
Debarshi jana

Background/ Context: Corticosteroids, despite being a very effective line of treatment for various disorders is known to have a wide range of adverse effects. The use of systemic and topical steroids has been associated with cataract formation, however the ophthalmic side effects of application of steroid on skin away from the face has not been studied in depth. With increasing use of corticosteroids as rst line of therapy in treatment of various dermatological conditions, the ocular side effects, if any, of these preparations, cannot be overlooked. Aim: To study the incidence of cataract in patients using skin preparations of corticosteroids away from the face and also to correlate the dose and duration of steroid therapy to incidence of cataract. Materials & Methods: 50 patients with dermatological disorders who were being treated with dermatological steroids, on sites other than the face and periorbital region, for a period of more than six months consisted of the study group. The study group consisted of patients in the age group of 20 – 60 years. The study was conducted over a period of two years at a tertiary care hospital. Visual acuity, Slit lamp biomicroscopy, applanation tonometryand detailed fundus examination using 90D lens were carried out. Results: The incidence of cataract was signicantly higher in patients using dermatological steroids away from the face. Prolonged duration of use of these steroids also indicated a signicantly higher incidence of cataract. However, a larger population based study needs to be carried out to study the relationship between potency of steroid and incidence of cataract, although preliminary studies indicate a denite correlation between the two. Conclusions: Despite, steroids being used away from the face, there was a denite increase in the incidence of cataract. Before coming to any rm conclusions it would be advisable to reproduce the study in a larger population. However from the present pilot study it is prudent to advocate judicious use of innocuous looking steroid creams as they can cause signicant adverse effects


Author(s):  
Skandashree B. S. ◽  
Hema N. G. ◽  
Surendran K. A. K.

Background: Topical steroids are the most commonly prescribed drugs in dermatology. The adverse effects of steroid misuse are noticeable 3 to 4 weeks after application. Steroid rosacea, hypertrichosis and acneiform eruptions are few of them. A new entity known as topical steroid dependent face, topical steroid dependent face (TSDF) has been recently coined to encompass symptoms such as erythema, burning sensation on attempted cessation of topical steroid application.Methods: A questionnaire-based analysis was done among patients attending dermatology outpatient department of government medical college hospital, Mysore between November 2018 to May 2019. Prior approval of the institutional ethics committee, and consent of patients were obtained. A total of 200 outpatients with facial dermatosis using topical steroids on face for a period greater than one month were taken up for study.Results: The results included population across different age groups, between 16 to 60 years. 56% belonged to the age group of 16 to 30 years. Most common steroid abused was mometasone cream 0.1% (50%), betamethasone valerate cream 0.1% (24.5%) followed by clobetasol ointment 0.05% (21.5%). The major adverse effect with steroid abuse, were acne 72% facial redness 67%. Hyperpigmentation 51%, hypertrichosis 32.5% and skin atrophy 21%.Conclusions: The present study highlights and creates awareness on the burden of facial topical steroid abuse and the poor attitude towards them.


2021 ◽  
Vol 19 (2) ◽  
pp. 26-33
Author(s):  
Pratik Gahalaut ◽  
Mriganka Mehra ◽  
Nitin Mishra ◽  
Madhur Kant Rastogi ◽  
Vasudha Bery

Introduction Superficial tinea infections are some of the most common dermatological conditions in the elderly. Recently, few studies done showed an abrupt increase in dermatophytic infection in adults; however, similar recent studies describing dermatophytosis in the elderly are lacking. The aims and objectives of this study were to identify the epidemiological profile of dermatophytoses among the elderly population. Materials and Methods This was a single centre, observational cross-sectional study conducted at a tertiary care Medical College Hospital in North India over 12 months including patients of dermatophytosis (KOH confirmed) aged 60 years or more. Results A total of 192 patients were enrolled, among which 68.7% were males. The extensive disease was present in 56.2%. History of topical steroid usage was present in 79.2%. The mean duration of disease was 23.8 weeks among which chronic disease was seen in 25%. Various other demographic characteristics were identified. Various risk factors for extensive disease, like gender, topical steroids use, urban residence, higher socioeconomic status, longer duration of disease, positive family history, diabetics, regular alcohol and tobacco consumption, were also noted in the present study. Conclusion The present concludes increased prevalence in women, delay in seeking treatment among them, a rising proportion of chronic and extensive dermatophytosis, rising atypical clinical presentation and higher predilection for tinea cruris and onychomycosis.


2021 ◽  
Vol 14 (02) ◽  
pp. 955-959
Author(s):  
Vatsala Maheshwari ◽  
Richa Chaturvedi ◽  
Sonali Meshram ◽  
Rahul Bhalsinge

Introduction : Topical steroids are most commonly being used today. Mostly these are being misused due to lack of awareness of their adverse effects. Malpractice and easy availability of these agents also responsible for their abuse. Aim : To Evaluate Topical Steroid abuse in various parameters according to CDSCO ADR forms. Objectives : This study was conducted to know the extent of abuse of topical steroid ,along with clinical profile and mode of accessibility in dermatology department of a teaching institute of tertiary health care centre of central India. Material and Method: First 200 patients of adverse drug reaction attending dermatology department were screened according to ICSR form of CDSCO in a period of December 2015 to November 2016 and 181 patients of them who gave history of topical steroid application were further analyzed. Result: Most commonly affected people belong to age of 21 to 30 years (41.98%),Tinea incognito (58%) was the commonest manifestation of steroid abuse, Tinea (58%)was the most common indication of steroid application, self medication (46.40%) was most common mode of steroid accessibility, betamethasone (61.87%) was most commonly applied topical steroid. Conclusion :Self medication and over the counter drug use were most common mode of steroid accessibility both can be controlled by making strict health regulatory policies . Simultaneously health education program must be targeted to young population who are more vulnerable to steroid abuse to make them aware regarding harmful effects of unguided or misguided use of topical steroid.


Author(s):  
Vontela Rohit ◽  
S. Rajesh Reddy ◽  
Narendar Gajula ◽  
Karing Deepthi

<p class="abstract"><strong>Background:</strong> Topical corticosteroids (TC), commonly used for a wide range of skin disorders, are associated with many side effects with their overuse, abuse and over-the-counter use as a cosmetic. This article aims to study clinical presentation of various dermatoses induced by abuse of TC in order to bring awareness among patients and practitioners to use topical corticosteroids with utmost caution.</p><p class="abstract"><strong>Methods:</strong> This study was conducted at DVL department of a tertiary care teaching hospital over 23 consecutive months. A total of 200 consecutive patients of all ages and both genders with topical steroid induced dermatoses were included in the study. A detailed clinical evaluation was undertaken, data was then recorded and analysed.</p><p class="abstract"><strong>Results:</strong> Majority of the patients were females (56%). Most common age group was 20-29 years (42%). Majority used TC as a remedy for dermatophytosis (38%), followed by use as a fairness/cosmetic cream (20%). Most of patients (29.5%) used TC for 6 months duration. Most commonly used TC formulation was 0.05% clobetasol propionate (37.5%). Majority patients (62%) did not have a valid prescription of which 47% used TC on Quacks’s advice. The most common side effects encountered were tinea incognito (33%), steroid-induced acne (20.5%), hyperpigmentation (14.5%), and hypopigmentation in 22 (11%).</p><p class="abstract"><strong>Conclusions:</strong> Present study highlights irrational prescription of TC by non-dermatologists for dermatophytosis which are very common in this particular study region and emphasizes the need to educate patients about serious adverse effects of TC abuse.</p>


Author(s):  
Sarankumar Sudhakar ◽  
Kayalvizhi V. A. ◽  
Syediqbal Sikkanthar ◽  
Madhanchand Muthukrishnan

<p class="abstract"><strong>Background:</strong> Abuse of topical corticosteroids (TCs), especially over the face, is prevalent worldwide with India as no exception. Lack of adequate specialist services, the practice of self-medication and easy access over the counter (OTC) has resulted in widespread abuse. Aim of this study was to assess the magnitude of topical steroid abuse and its diverse cutaneous side effects in commercial sex workers.</p><p class="abstract"><strong>Methods:</strong> A cross-sectional analytical study was conducted among commercial sex workers (both females and transgender) attending the STI clinic in the study institution for 6 months. A semi-structured questionnaire was given and type of steroid cream used, frequency, duration, the reason for application and source of information for its use were recorded. Clinical patterns of side-effects were noted. Clinical photographs were taken. Descriptive statistical analysis was done, (SPSS 21.0).<strong></strong></p><p class="abstract"><strong>Results:</strong> Out of the total 180 commercial sex workers (CSWs), 80 were transgender and 100 were females. The most common steroid used was betamethasone valerate followed by the triple regimen containing mometasone. The reasons for TCs use were fairness (72%) followed by melasma (18%) and acne (10%). Side effects were seen in 77.5% of transgender and 66% of female CSWs. Common side effects noted were erythema (40%), acne (26%) and, pigmentation (18%).</p><p class="abstract"><strong>Conclusions:</strong> The main reason for TCs abuse in our country as a fairness agent is obsessiveness with fair skin colour. Various studies on TCs abuse were done in the general population but none of the studies focuses on a particular group as in this study.</p>


2021 ◽  
Vol 19 (1) ◽  
pp. 71-75
Author(s):  
Sushil Paudel ◽  
Niraj Parajuli ◽  
Sudip Chandra Dahal ◽  
Sudarshan Paudel

Background: Steroid-modified tinea, also known as tinea incognito, is an infection by the dermatophytes, where the clinical morphology is modified due to corticosteroids, either systemic or topical. Rampant use of topical corticosteroids has led to increasing recurrence in tinea infections. Methods: All consenting cases of tinea presenting to outpatient department of dermatology department of Civil Service Hospital from March to August 2020 for a total of 6 months were included in this study. Tinea infection involving only the palms, soles, nails or scalp were excluded.Results: A total of 200 patients were included in this study. Among these, 175 patients (87.5%) were using topical corticosteroids. A significant association was noted between dermatophyte infection of more than one month and topical corticosteroids use (p<0.05). This study revealed that males were using super-potent topical corticosteroids more as compared to females (p<0.05). Moreover, no association was noted between the level of education attained and the use of topical corticosteroids (p=0.91). Only 25 (12%) patients were either using correct or no topical medications during the time of consultation with the dermatologist. Among the patients using topical corticosteroids, 155 (88.6%) patients were using them on recommendation of the local pharmacist and only 2 (1.2%) patients were prescribed by a physician. Conclusions: In short, use of topical steroids was rampant among patients with tinea whilst 77.5% patients procured steroid topicals over-the-counter. Hence, a tougher law and strict regulatory guidelines deemed necessary to curb the unauthorized and rampant sale of these medicines.Keywords: Dermatophytes; over-the-counter; steroid misuse; self-medications; tinea; topical corticosteroid


Author(s):  
Rashmitha Nagaraj ◽  
Shruthi Hassan Nagaraj

<p class="abstract"><strong>Background:</strong> Topical corticosteroids (TCS) are one among the most commonly prescribed medications in the ambulatory setting. They exhibit anti-inflammatory effects, immunosuppressive effect, antiproliferative effects and vasoconstriction.</p><p class="abstract"><strong>Methods:</strong> A total of 400 patients who had visited the outpatient department or was admitted in the department of dermatology and had applied topical corticosteroids for a duration of 2 or more weeks were included for the study over a period of 2 months in June and July 2018. This study is clinical and observational, to evaluate the topical corticosteroids abuse cases.<strong></strong></p><p class="abstract"><strong>Results:</strong> Out of 400 people 304 [76%] patients were either recommended or prescribed TCS by a non-physician source. And the rest 96 [24%] patients were been prescribed by the medical fraternity. Majority of patients have applied TCS belonging to super potent class [294/400] duration of usage varied from 2 weeks to 2 years and amount from 10 to 240 g. The most common consequences of TCS abuse was rebound phenomenon followed by hypopigmentation, striae.</p><strong>Conclusions:</strong> Prolonged and continuous use of TCS can cause many adverse effects with varying clinical presentation. Treatment is difficult as there is rebound phenomenon with discontinuation of TCS. Gradual withdrawals of TCS with supplementation of adequate treatment to the present clinical issue are usually recommended to get good clinical results.


JMS SKIMS ◽  
2020 ◽  
Vol 23 (1) ◽  
pp. 48-49
Author(s):  
Javaid Ahmad Bhat ◽  
Shariq Rashid Masoodi

Apropos to the article by Dr Bali, titled “Mupirocin resistance in clinical isolates of methicillin-sensitive and resistant Staphylococcus aureus in a tertiary care centre of North India” (1), the authors have raised important issue of emerging antimicrobial resistance (AMR). Antimicrobial resistance is an increasingly serious threat to global public health that requires action across all government sectors and society. As per WHO, AMR lurks the effective prevention and management of an ever-increasing spectrum of infections caused by bacteria, parasites, fungi and viruses. Novel resistance mechanisms are emerging and spreading globally, threatening the man’s ability to treat common infectious diseases.


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