A Study on Design Guidelines for the Restoration of Cognitive Abilities in Early Stage Dementia Patients -Focusing on Behavior-based Usability of Digital Device for Reality Orientation Recovery-

2020 ◽  
Vol 26 (3) ◽  
pp. 379-391
Author(s):  
Jin Seok Lee ◽  
Hyunjee You ◽  
Tae Hyun Yoon ◽  
Hoo Sung Kim
Keyword(s):  
Cognitive Abilities ◽  
Early Stage ◽  
Design Guidelines ◽  
Digital Device ◽  
Dementia Patients ◽  
Behavior Based ◽  
Reality Orientation

scholarly journals 404 - Effect of Psychoeducation Modul on the Administration of Psychotropic Drugs for Patients with Behavioral and Psychological Symptoms of Dementia at the RS Dr. H. Marzoeki Mahdi Bogor on Caregivers

2020 ◽  
Vol 32 (S1) ◽  
pp. 120-120
Keyword(s):  
Psychotropic Drugs ◽  
Cognitive Abilities ◽  
Health Workers ◽  
Psychological Symptoms ◽  
Clinical Syndrome ◽  
List Type ◽  
Study Program ◽  
Dementia Patients ◽  
Patients Experience ◽  
Behavioral And Psychological Symptoms

Name : Yuniar Pukuk KesumaStudy program : Psychiatry, Specialist II Geriatric PsychiatryCounsellor : Dr.dr. Martina Wiwie S. Nasrun, Sp.KJ(K)Background:Dementia is a clinical syndrome characterized by a decline in cognitive abilities and memory deficits globally. About 90% of patients experience behavioral and psychological symptoms. The use of psychotropic drugs is influenced by the patient symptoms, burden of the caregiver, and the habit of health workers.Objective:To determine the effect of psychoeducation modules to caregivers to increase knowledge, decrease of psychotropic drugs, reduce symptoms and burden of caregivers.Methods:There are 2 steps of studies. The first was a qualitative study to create psychoeducation module and the second was to conduct a pre-experimental study (one group pretest-posttest study). Psychoeducation is given in 2 consecutive weeks.Results:Fourty caregivers of dementia patients aged 41.3 (± 9.72) years. The psychoeducation modules is associated with decreasing symptoms and the use of psychotropic drugs, increasing knowledge and decreasing the burden of caregivers. At the end, 23% of patients were able to stop using psychotropic drugs and 62% of patients reduced their dose and/or the amount of psychotropic drugs.Conclusion:The psychoeducation modules to caregivers is associated with a decrease of patient symptoms and the use of psychotropic drugs. Psychoeducation also increases the knowledge of the caregiver and decreases the burden of the caregiver so that this psychoeducation module can be an additional therapy for patients with dementia.

scholarly journals Collage technique may provide new perspectives for Alzheimer patients by exploring messages from their inner world

2009 ◽  
Vol 3 (4) ◽  
pp. 299-302 ◽  
Author(s):  
Mitsue Meguro ◽  
Junichi Ishizaki ◽  
Kenichi Meguro
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Early Stage ◽  
Cognitive Assessments ◽  
Dementia Patients ◽  
Inner World

Abstract Although the collage art technique has been introduced as a psychotherapeutic method, it has not been fully applied in dementia. Objectives: To analyze characteristics of the collage articles produced by patients with Alzheimer's disease (AD). Methods: Twenty AD patients were asked to select and place several clippings as they wished. The MMSE was used for cognitive assessments. Results: Simplification and poor organization in their articles were found. The themes of one patient were found to change according to behavior. We discussed the images of the articles, especially spiritual images in the early stage and family images in the later stage. Conclusions: We concluded that the collage technique could provide new perspectives for dementia patients by exploring messages from their inner world.

scholarly journals Automated Classification of Normal Control and Early-Stage Dementia Based on Activities of Daily Living (ADL) Data Acquired from Smart Home Environment

2021 ◽  
Vol 18 (24) ◽  
pp. 13235
Author(s):  
Lee-Nam Kwon ◽  
Dong-Hun Yang ◽  
Myung-Gwon Hwang ◽  
Soo-Jin Lim ◽  
Young-Kuk Kim ◽  
...  
Keyword(s):  
Activities Of Daily Living ◽  
Normal Control ◽  
Daily Living ◽  
Smart Home ◽  
Early Stage ◽  
Machine Learning Techniques ◽  
Evaluation Tool ◽  
Dementia Patients ◽  
Diagnosis Of Dementia

With the global trend toward an aging population, the increasing number of dementia patients and elderly living alone has emerged as a serious social issue in South Korea. The assessment of activities of daily living (ADL) is essential for diagnosing dementia. However, since the assessment is based on the ADL questionnaire, it relies on subjective judgment and lacks objectivity. Seven healthy seniors and six with early-stage dementia participated in the study to obtain ADL data. The derived ADL features were generated by smart home sensors. Statistical methods and machine learning techniques were employed to develop a model for auto-classifying the normal controls and early-stage dementia patients. The proposed approach verified the developed model as an objective ADL evaluation tool for the diagnosis of dementia. A random forest algorithm was used to compare a personalized model and a non-personalized model. The comparison result verified that the accuracy (91.20%) of the personalized model was higher than that (84.54%) of the non-personalized model. This indicates that the cognitive ability-based personalization showed encouraging performance in the classification of normal control and early-stage dementia and it is expected that the findings of this study will serve as important basic data for the objective diagnosis of dementia.

scholarly journals Use of Antipsychotics in Dementia Patients: A Descriptive Study

2020 ◽  
Vol 1 (4) ◽  
pp. 9-19
Author(s):  
Ziske Maritska ◽  
Muhammad Hilal Atthariq Ramadhan ◽  
Bintang Arroyantri Prananjaya
Keyword(s):  
Antipsychotic Drug ◽  
Cognitive Abilities ◽  
Secondary Data ◽  
Descriptive Study ◽  
Antipsychotic Treatment ◽  
Dopamine Antagonist ◽  
Elderly Age ◽  
Antipsychotic Therapy ◽  
Behavioural Symptoms ◽  
Dementia Patients

ABSTRACT Introduction. Dementia is a chronic progressive syndrome in which there is a decrease in the function of cognitive abilities including memory impairment, thinking ability, orientation, understanding, calculation, language, and assessment but without impaired consciousness. Apart from cognitive impairment, dementia is often accompanied by psychological symptoms and behavioural symptoms so that antipsychotic therapy is needed to overcome this. This study aims to identify the description of the use of antipsychotics in patients with dementia at Dr Mohammad Hoesin Palembang in the period 1 January 2014-31 December 2018. Methods. This research was a descriptive study using secondary data in the form of medical records of dementia patients receiving antipsychotic therapy at Dr Mohammad Hoesin General Hospital, Palembang. Samples were taken using a total sampling method. Results. There were 29 dementia patients (38.67%) receiving antipsychotic therapy. Most of the dementia patients who received antipsychotic therapy were in the late elderly age (27.59%) and were female (55.17%). The most commonly administered antipsychotic drug is haloperidol from the dopamine receptor antagonist (60%) with the most frequent dose of 0.5 mg (34.48%). Risperidone from the serotonin-dopamine antagonist class is the second most frequently prescribed antipsychotic drug (34.28%) at a dose of 1 mg (17.28%). The mean of haloperidol was 425 days, and risperidone was 295.5 days. Conclusion. Although in theory, psychological and behavioural symptoms are often found in dementia cases, not all dementia patients in RSUP Dr Mohammad Hoesin Palembang received antipsychotic therapy. People living with dementia who receive antipsychotic treatment get various types of drugs, dosages, and frequencies.

scholarly journals Approach to early stage dementia patients and their families

2019 ◽  
Vol 23 (3) ◽  
pp. 128-135
Author(s):  
Güzel Dişcigil ◽  
F. Sıla Ayan
Keyword(s):  
Early Stage ◽  
Dementia Patients

Immersive Virtual Reality for Older Adults

2021 ◽  
Vol 14 (3) ◽  
pp. 1-30
Author(s):  
Vero Vanden Abeele ◽  
Brenda Schraepen ◽  
Hanne Huygelier ◽  
Celine Gillebert ◽  
Kathrin Gerling ◽  
...  
Keyword(s):  
Older Adults ◽  
Virtual Reality ◽  
Cognitive Abilities ◽  
Older Persons ◽  
Design Guidelines ◽  
Immersive Virtual Reality ◽  
Design Recommendations ◽  
Education Levels ◽  
Positive Experiences

Despite the proliferation of research on immersive virtual reality (IVR) technologies for older adults, comprehensive guidelines on designing immersive and engaging VR for older adults remain sparse. Therefore, we first compounded 67 guidelines based on published literature. Next, to empirically ground these design recommendations, we provided 37 older adults of diverse ages, education levels, and cognitive abilities with a first VR experience. Analyzing interviews with the 37 older adults via the Laddering method, we found that they generally reported positive experiences with their first VR exposure. With these deepened insights, we reflect on, nuance, and contextualize existing design guidelines, and formulate points to bear in mind when designing accessible and engaging VR experiences for older persons.

Help Me! MyDem Application for Early Stage Dementia Patients

2018 ◽  
Author(s):  
K.S. Savita ◽  
Jose Jorge Do Amaral Marrima ◽  
Manoranjitham Muniandy ◽  
A. I. Z. Abidin ◽  
S. M. Taib
Keyword(s):  
Early Stage ◽  
Dementia Patients

scholarly journals miR-132 regulates the expression of synaptic proteins in APP/PS1 transgenic mice through C1q

2019 ◽  
Vol 63 (2) ◽  
Author(s):  
Nan Xu ◽  
Ang-Di Li ◽  
Li-Li Ji ◽  
Yao Ye ◽  
Zhen-Yu Wang ◽  
...  
Keyword(s):  
Transgenic Mice ◽  
Cognitive Abilities ◽  
Early Stage ◽  
Amyloid Β ◽  
In Silico Analysis ◽  
Synaptic Proteins ◽  
Downstream Target ◽  
Key Factor ◽  
The Central Nervous System ◽  
Synapse Degeneration

Cognitive impairment in Alzheimer’s disease (AD) is usually accompanied by synaptic loss in both the hippocampus and neocortex. In the early stage of AD, amyloid β-induced synapse changes is the main reason, while in the later stage, the accumulation of Tau protein promotes synapse degeneration as the key factor leading to dementia. MicroRNA (miRNA) is closely related to the expression changes of many AD-related genes. One of the most abundant brain-enriched miRNAs is miR-132, which has been shown to regulate both neuron morphogenesis and plasticity. It has been reported that miR-132 is significantly reduced in the brains of Alzheimer’s patients. Genetic deletion of miR-132 in mice promotes Aβ deposition, leading to impaired memory and enhanced Tau pathology, but how the miRNA-mediated gene expression dysregulation contributes to AD pathology remains unclear. Here we found the possible downstream target of miR-132 by in silico analysis, namely C1q. C1q is the primary protein of classical complement cascade, which is highly expressed in the synaptic regions of the central nervous system in Alzheimer’s patients. However, it is not clear whether miR-132 plays a role in AD through regulating C1q. To address this question, the APP/PS1 transgenic mice were transfected with miR-132 and given C1 inhibitors. Behavior tests were conducted to assess memory and cognitive abilities seven days after administration. In addition, we analyzed the expression of PSD95, Synapsin-1 and phosphorylated (p)-Synapsin. We found that the expression levels of the synaptic proteins treated with miR-132 or C1INH were significantly increased compared with the AD group. Further RT-qPCR result suggested that miR-132 might regulate C1q expression in AD.

The applicability of the cognitive abilities screening instrument–short (CASI-S) in primary care in Brazil

2015 ◽  
Vol 28 (1) ◽  
pp. 93-99 ◽  
Author(s):  
Glaucia Martins de Oliveira ◽  
Juliana Emy Yokomizo ◽  
Laís dos Santos Vinholi e Silva ◽  
Laura Ferreira Saran ◽  
Cássio M. C. Bottino ◽  
...  
Keyword(s):  
Primary Care ◽  
Internal Consistency ◽  
Cognitive Abilities ◽  
Temporal Stability ◽  
Screening Instrument ◽  
Eastern Region ◽  
Limited Information ◽  
Cognitive Screening ◽  
Dementia Patients ◽  
Normal Controls

ABSTRACTBackground:The Cognitive Abilities Screening Instrument – Short (CASI-S) is a brief cognitive screening test. However, there is limited information regarding its applicability in primary care.Objectives:To ascertain whether the CASI-S differentiates between dementia patients and normal controls in primary care; to examine its correlation with other cognitive instruments, to analyze its internal consistency, test-retest stability, and diagnostic accuracy.Methods:In a case-control study, carried out at two Primary Care Units (PCUs) in the eastern region of the city of São Paulo, 47 older adults were diagnosed with dementia according to DSM-IV criteria (mean age = 76.81 ± 7.03 years), and 55 were classified as normal controls (mean age = 72.78 ± 7.37 years), by a multidisciplinary panel which had access to results from a comprehensive cognitive battery and the patients’ health data. The present analyses included results from the Mini-Mental State Examination (MMSE). The CASI-S was not used to determine diagnostic status.Results:The CASI-S was easily applied in the primary care setting. There was a significant performance difference (p < 0.001) between dementia patients (15.57 ± 7.40) and normal controls (26.67 ± 3.52) on the CASI-S. CASI-S scores correlated with age (ρ = −0.410, p < 0.001), educational level (ρ = 0.373, p < 0.001), and MMSE score (ρ = 0.793, p < 0.001). The internal consistency of the CASI-S was high (α = 0.848) and the correlation between test and retest was 0.688, suggesting adequate temporal stability. In the ROC curve analyses, scores of 22/23 generated an area under the curve of 0.907, with sensitivity of 93% and specificity of 81%.Conclusions:The CASI-S can be useful for dementia screening in primary care in Brazil.

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