scholarly journals Closure of an Oroantral Communication Using Leucocyte-Platelet Rich Fibrin: A Novel Technique Using Regenerative Medicine

Author(s):  
Cameron Y Lee

Oroantral communication (OAC) is a common complication following extraction of maxillary posterior teeth because of the close anatomic proximity of the roots to the maxillary sinus. The most frequent methods described in the literature to close an oroantral communication involve buccal or palatal rotational advancement flap surgery or use of the buccal fat pad. These surgical procedures require advanced surgical skill and are associated with donor sit morbidity, such as avascular flap necrosis that can lead to soft tissue graft failure to close the OAC, infection and extreme postoperative patient discomfort that affects patient quality of life. This paper describes a novel technique using leucocyte platelet-rich fibrin matrix obtained from the patient’s own venous blood that leads to predictable soft tissue regeneration and closure of the OAC. This regenerative medicine procedure is clinician friendly, less traumatic compared to traditional methods of OAC closure with minimal postoperative recovery for the patient.    

2020 ◽  
Vol 9 (3) ◽  
Author(s):  
Rodrigo Capalbo-Silva ◽  
Hiskell Francine Fernandes e Oliveira ◽  
Henrique Hadad ◽  
Bruno Coelho Mendes ◽  
Breno dos Reis Fernandes ◽  
...  

A comunicação bucosinusal trata-se da comunicação não natural da cavidade bucal com o seio maxilar, estando muitas vezes relacionada a extração dos dentes superiores posteriores. A literatura apresenta diversas opções de tratamento para esses casos, entre eles o fechamento com o retalho pediculado com o corpo adiposo bucal. O objetivo deste trabalho foi relatar um caso de fístula bucosinusal em paciente diabético, discutindo alternativas cirúrgicas correlacionadas com problema sistêmico do paciente e características locais do defeito. Paciente do sexo masculino, 55 anos de idade, com histórico de dez dias de exodontia do elemento 27, com queixa de passagem de ar ao meio bucal através do sítio cirúrgico. Com base nos exames, o diagnóstico definitivo foi de comunicação bucosinusal, sendo estipulado o tratamento cirúrgico para o fechamento da comunicação através de duas camadas com o corpo adiposo da bochecha seguido do retalho vestibular. No acompanhamento de 8 meses e meio o paciente não apresenta queixas e pode-se observar o fechamento completo da comunicação bucosinusal. O retalho pediculado do corpo adiposo bucal seguido do retalho vestibular mostrou-se efetivo no tratamento da fístula bucosinusal em paciente diabético controlado.Descritores: Fístula Bucoantral; Cirurgia Bucal; Diabetes Mellitus.ReferênciasLozano-Carrascal N, Salomó-Coll O, Gehrke SA, Calvo-Guirado JL, Hernández-Alfaro F, Gargallo-Albiol J. Radiological evaluation of maxillary sinus anatomy: A cross-sectional study of 300 patients. Ann Anat. 2017;214:1-8.Jang JK, Kwak SW, Ha JH, Kim HC. Anatomical relationship of maxillary posterior teeth with the sinus floor and buccal cortex. J Oral Rehabil. 2017;44(8):617-25. Khandelwal P, Hajira N. Management of Oro-antral Communication and Fistula: Various Surgical Options. World J Plast Surg. 2017;6(1):3-8.Parvini P, Obreja K, Begic A, et al. Decision-making in closure of oroantral communication and fistula. Int J Implant Dent. 2019;5(1):13.Lin PT, Bukachevsky R, Blake M. Management of odontogenic sinusitis with persistent oro-antral fistula. Ear Nose Throat J. 1991;70(8):488-90.Al-Juboori MJ, Al-Attas MA, Magno Filho LC. Treatment of chronic oroantral fistula with platelet-rich fibrin clot and collagen membrane: a case report. Clin Cosmet Investig Dent. 2018; 10:245-49.Kiran Kumar Krishanappa S, Eachempati P, Kumbargere Nagraj S, Shetty NY, Moe S, Aggarwal H et al.  Interventions for treating oro-antral communications and fistulae due to dental procedures. Cochrane Database Syst Rev. 2018;8(8):CD011784. Darr A, Jolly K, Martin T, Monaghan A, Grime P, Isles M et al. Three-layered technique to repair an oroantral fistula using a posterior-pedicled inferior turbinate, buccal fat pad, and buccal mucosal advancement flap. Br J Oral Maxillofac Surg. 2018;56(7):638-39.Parvini P, Obreja K, Sader R, Becker J, Schwarz F, Salti L. Surgical options in oroantral fistula management: a narrative review. Int J Implant Dent. 2018;4(1):40. Lin PT, Bukachevsky R, Blake M. Management of odontogenic sinusitis with persistent oro-antral fistula. Ear Nose Throat J. 1991;70(8):488-90.Borgonovo AE, Berardinelli FV, Favale M, Maiorana C. Surgical options in oroantral fistula treatment. Open Dent J. 2012;6:94-8.Ribeiro FS, de Toledo CT, Aleixo MR, Durigan MC, Silva WC, Bueno SK et al. Treatment of Oroantral Communication Using the Lateral Palatal Sliding Flap Technique. Case Rep Med. 2015;2015:730623.Erdoğan O, Esen E, Ustün Y. Bony palatal necrosis in a diabetic patient secondary to palatal rotational flap. J Diabetes Complications. 2005;19(6):364-67.Tideman H, Bosanquet A, Scott J. Use of the buccal fat pad as a pedicled graft. J Oral Maxillofac Surg. 1986;44(6):435-40.Yang S, Jee YJ, Ryu DM. Reconstruction of large oroantral defects using a pedicled buccal fat pad. Maxillofac Plast Reconstr Surg. 2018; 40(1):7.Raldi FV, Sardinha SCS, Albergaria-Barbosa JR. Fechamento de comunicação bucossinusal usando enxerto pediculado com corpo adiposo bucal. BCI. 2000;7(25):60-3.Poeschl PW, Baumann A, Russmueller G, Poeschl E, Klug C, Ewers R. Closure of oroantral communications with Bichat's buccal fat pad. J Oral Maxillofac Surg. 2009;67(7):1460-66.Batra H, Jindal G, Kaur S. Evaluation of different treatment modalities for closure of oro-antral communications and formulation of a rational approach. J Maxillofac Oral Surg. 2010;9(1):13-8. Weinstock RJ, Nikoyan L, Dym H. Composite three-layer closure of oral antral communication with 10 months follow-up-a case study. J Oral Maxillofac Surg. 2014;72(2):266.e1-266.e2667.Candamourty R, Jain MK, Sankar K, Babu MR. Double-layered closure of oroantral fistula using buccal fat pad and buccal advancement flap. J Nat Sci Biol Med. 2012;3(2):203-5.


2015 ◽  
Vol 9 (1) ◽  
Author(s):  
A.E. di Lauro ◽  
D. Abbate ◽  
B. Dell’Angelo ◽  
G.A. Iannaccone ◽  
F. Scotto ◽  
...  

Medicine ◽  
2020 ◽  
Vol 99 (40) ◽  
pp. e22507
Author(s):  
Aimin Cui ◽  
Jing Zhou ◽  
Mahmoud Mudalal ◽  
Yao Wang ◽  
Jia Wang ◽  
...  

Oncotarget ◽  
2016 ◽  
Vol 7 (23) ◽  
pp. 35390-35403 ◽  
Author(s):  
Fang-Tian Xu ◽  
Zhi-Jie Liang ◽  
Hong-Mian Li ◽  
Qi-Liu Peng ◽  
Min-Hong Huang ◽  
...  

2018 ◽  
Vol 44 (6) ◽  
pp. 471-492 ◽  
Author(s):  
Shahram Ghanaati ◽  
Carlos Herrera-Vizcaino ◽  
Sarah Al-Maawi ◽  
Jonas Lorenz ◽  
Richard J Miron ◽  
...  

Platelet-rich fibrin is a blood concentrate system used for soft tissue and bone tissue regeneration. In the last decade, platelet rich fibrin (PRF) has been widely used in different indication fields, particularly in oral and maxillofacial surgery. This review investigates the level of scientific evidence of published articles related to the use of PRF for bone and soft tissue regeneration in dentistry and maxillofacial surgery. An electronic literature research using the biomedical search engine “National Library of Medicine” (PubMed-MEDLINE) was performed in May 2017. A total of 392 articles were found, 72 of which were classified for each indication field. When comparing PRF with biomaterials vs biomaterial alone in sinus lift (5 studies; IIa), no statistically significant differences were detected. Socket preservation and ridge augmentation using PRF significantly enhanced new bone formation compared to healing without PRF (7 studies Ib, IIa, IIb). Reepithelialization and bone regeneration was achieved in 96 of 101 patients diagnosed with medication-related osteonecrosis of the jaw (5 studies, III). In periodontology, PRF alone (6 studies; Ib, IIa, IIb) or its combination with biomaterials (6 studies; Ib, IIa, IIb) significantly improved the pocket depth and attachment loss compared to a treatment without PRF. Over 70% of the patients were part of studies with a high level of scientific evidence (randomized and controlled prospective studies). This published evidence (38 articles), with a high scientific level, showed that PRF is a beneficial tool that significantly improves bone and soft tissue regeneration. However, the clinical community requires a standardization of PRF protocols to further examine the benefit of PRF in bone and soft tissue regeneration in reproducible studies, with a higher scientific level of evidence.


Author(s):  
Dr. M. A. Awal ◽  
Dr. Mahmuda Akhter

Oroantral communication (OAC) is a pathological communication between the oral cavity and the maxillary sinus. Numerous methods are described to manage an acute OAC with some adverse effect and limitations. Our comparative cross-sectional study tried to evaluate the efficacy of Platelet-rich fibrin (PRF) by comparing with the Buccal advancement flap for the closure of acute OAC on 38 patients (n=38), were divided into two groups. One group treated by traditional Buccal advancement flap and compared with the group treated with PRF clot and membranes. Statistically significant better healing with less complication was observed (P< 0.05) in group treated with PRF clot and membranes considering as an effective way to manage acute oroantral communications.


Author(s):  
Geetanjali Singh ◽  
Bhawna Kumari ◽  
Harangad Singh Grover ◽  
Akriti Mahajan ◽  
Farhat Jabeen ◽  
...  

A huge number of studies have demonstrated that platelet-rich preparations applied to surgical sites, injuries, or wounds are effective way to promote soft tissue healing and bone growth. The potential use of  platelet rich preparations like Platelet - rich plasma and Platelet - rich fibrin are new boon to dentistry termed under the general acronyms PRP (Platelet-Rich Plasma) or PRF (Platelet-Rich Fibrin), is an important current transversal field of research across many fundamental and clinical disciplines.The third important is PRGF.  Plasma Rich in Growth Factor (or PRGF) is a type of plasma enriched of proteins and circulating growth factors able to aid the bone and soft tissue regeneration. PRGF includes plasma proteins and coagulative factors and is then more valuable compared to PRP. There are many scientific literature which cover one or other concise aspect of platelet rich preparation. This review aims at covering all basic definitions, key element, history, preparation, differences between PRF and PRP and applications in a simplified manner.


2011 ◽  
Vol 10 (2) ◽  
pp. 116
Author(s):  
Wiwiek Poedjiastoeti

Oroantral communication (OAC)may occur when upper posterior teeth are removed, and occasionally, as a resultof trauma. This sinus perforation formed particularly when a maxillary molar with widely divergent roots adjacentto edentulous spaces is extracted. In this instance the sinus is likely to be pneumatized into the edentulous alveolarprocessus surrounding the tooth, which weakens the entire alveolus and brings the tooth apices into a closerrelationship with the sinus cavity. In order to avoid OAC, preoperative radiograph is needed. When perforation, ifsinus opening is small and disease free, effort should be made to establish blood clot in the extraction site andpreserve it in place. Soft tissue flap elevation is not required. Sutures are placed to reposition the soft tissue, and agauze pack is placed over the surgical site for 1-2 hours. Majority of patients treated in this manner showeduneventful healing when no evidence of preexisting sinus disease.


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