scholarly journals Factors Affecting Prevalence of Urinary Tract Infection in Neo-nates with Unexplained Hyperbilirubinemia: A Systematic Re-view and Meta-Analysis Study in Iran

2021 ◽  
Author(s):  
Fahimeh Bagheri Amiri ◽  
Sanaz Tavasoli ◽  
Nasrin Borumandnia ◽  
Maryam Taheri
Keyword(s):  
Urinary Tract Infection ◽  
Birth Weight ◽  
Urinary Tract ◽  
Tract Infection ◽  
Low Birth Weight ◽  
Meta Analysis ◽  
Female Gender ◽  
Normal Birth Weight ◽  
Normal Birth ◽  
Tract Infections

Background: The prevalence and risk factors of urinary tract infection (UTI) in neonates with unexplained hyperbilirubinemia are not studied thoroughly. Since the prevalence of UTI is highly variable in different areas and countries, this study aimed to review the existing data of Iranian neonates with UTI presented with unexplained hyperbilirubinemia. Methods: This study is a meta-analysis of Iranian newborns with unexplained hyperbilirubinemia. We identified all studies indexed in international (Web of Science, PubMed, Scopus, Google Scholar) and national (Science Information Database, Magiran) databases from 2000-2018. Search terms included: Urinary Tract Infections OR UTI AND urine OR culture OR microbio, jaundice OR icter OR hyperbili, AND Iran. Results: Overall, 4210 neonates from 17 studies were included. The pooled prevalence of UTI in neonates with unexplained hyperbilirubinemia was 6.81% (95% CI: 4.86-8.77). Considering the subgroups analyses; the prevalence of UTI was higher in the prolonged vs. not-prolonged state (8.34% vs. 4.00%), low birth weight vs. normal birth weight (7.81% vs. 4.51%), and exclusive vs. non-exclusive breastfeeding (8.84% vs. 4.72%). Male gender and low birth weight increased the risk of UTI about two times compared to the female gender and normal birth weight, respectively. The results of the analyses in neonates with unconjugated hyperbilirubinemia also showed the above-mentioned subgroup differences.  

scholarly journals Maternal Urinary Tract Infection: Is It Associated With Neonatal Urinary Tract Infection?

2021 ◽  
Author(s):  
Huseyin Bilgin ◽  
Emine Esin Yalinbas ◽  
Ilknur Elifoglu ◽  
Sahinde Atlanoglu
Keyword(s):  
Urinary Tract Infection ◽  
Birth Weight ◽  
Urinary Tract ◽  
Tract Infection ◽  
Low Birth Weight ◽  
Preterm Delivery ◽  
Control Group ◽  
Study Group ◽  
Infection Frequency ◽  
Tract Infections

Objective: Maternal urinary tract infection is associated with intrauterine growth restriction, preterm delivery and low birth weight. The purpose of this study was to evaluate whether maternal urinary tract infection is related to neonatal urinary tract infection. Materials and methods: The present prospective study included 230 singleton neonates. The participants were divided into two groups based on in utero exposure to maternal urinary tract infections. The study group (exposure to maternal urinary tract infection) included 115 neonates and the control group (without exposure to maternal urinary tract infection) included 115 healthy neonates. Physical examination, urinalysis, urine culture and urinary system ultrasonography were carried out for all neonates. Results: There were 153 deliveries by cesarean section and 77 vaginal births. There was no statistically significant difference between the groups in terms of gender distribution, maternal age, birth weight, mode of delivery, gravida and gestational age. Although the difference was not significant, the incidence of low birth weight and preterm delivery were higher in the study group in comparison to that in the control group. There was a statistically significant higher rate of neonatal urinary tract infection in the study group compared with control group (25.2% vs. 7.8%, p<0.001). The most commonly discovered pathogens were Escherichia coli, followed by Klebsiella spp., Proteus spp., and Serratia spp. in the study group. Conclusion: The results of this study showed that the presence of maternal urinary tract infection may contribute to increased urinary tract infection frequency in the neonatal period. Neonates at risk for a urinary tract infection should be regularly monitored due to nonspecific clinical presentation.

scholarly journals Infeções do Trato Urinário numa Coorte de Transplantados Renais

2014 ◽  
Vol 27 (3) ◽  
pp. 364 ◽  
Author(s):  
Ana Bispo ◽  
Milene Fernandes ◽  
Cristina Toscano ◽  
Teresa Marques ◽  
Domingos Machado ◽  
...  
Keyword(s):  
Risk Factors ◽  
Escherichia Coli ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Urinary Tract Infections ◽  
Hospital Admissions ◽  
Female Gender ◽  
Tract Infections

<strong>Introduction:</strong> Urinary tract infection is the most common infectious complication following renal transplantation and its frequency is insufficiently studied in Portugal. The aim of this study was to characterize the incidence of urinary tract infections and recurrent urinary tract infections in renal transplant recipients.<br /><strong>Material and Methods:</strong> This was a retrospective cohort observational study, obtained from clinical files of all patients who received a renal transplant at the Hospital of Santa Cruz, from January 2004 to December 2005, with a mean follow-up period of five years or until date of graft loss, death or loss of follow-up. After a descriptive analysis of the population, we used bivariate tests to identify risk factors for urinary tract infections.<br /><strong>Results:</strong> A total of 127 patients were included, with a 593 patients.year follow-up. We detected 53 patients (41.7%) presenting with at least one episode of urinary tract infection; 21 patients (16.5%) had recurrent urinary tract infection. Female gender was the only risk factor associated with the occurrence of urinary tract infections (p &lt; 0.001, OR = 7.08, RR = 2.95) and recurrent urinary tract infections (p &lt; 0.001, OR = 4.66, RR = 2.83). Escherichia coli (51.6%), Klebsiella pneumoniae (15.5%) and Enterobacter spp (9.9%) were the<br />most frequently identified pathogens. Patients did not reveal an increased mortality or allograft loss. However, urinary tract infections were the most important cause of hospital admissions.<br /><strong>Discussion:</strong> Female gender was the only risk factor for urinary tract infections in this population. Escherichia coli was the most frequent agent isolated.<br /><strong>Conclusion:</strong> Despite preventive measures, urinary tract infections remain an important cause of morbidity and hospital admissions.<br /><strong>Keywords:</strong> Urinary Tract Infections; Postoperative Complications; Risk Factors; Kidney Transplantation; Portugal.

scholarly journals Antibacterial data synthesis challenges: a systematic review of treatments for complicated gram-negative urinary tract infections

2021 ◽  
Author(s):  
Ryan Dillon ◽  
Jennifer Uyei ◽  
Rajpal Singh ◽  
Eilish McCann
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Meta Analysis ◽  
Complicated Urinary Tract Infection ◽  
Clinical Trial Data ◽  
Patient Characteristics ◽  
Heterogeneous Data ◽  
Eligibility Criteria ◽  
Tract Infections

Aim: To determine the suitability of network meta-analysis (NMA) using antibacterial treatment evidence in complicated urinary tract infection. Materials & methods: We conducted a systematic literature review to identify published clinical trial data for complicated urinary tract infection treatments. We performed a feasibility assessment to determine whether the available evidence would support the creation of a robust NMA, considering key assumptions of homogeneity, similarity and consistency. Results: Twenty-five trials met eligibility criteria. Risk of bias was low, and individual studies met their primary end point(s). Assumptions central to the conduct of a robust NMA were not met. Heterogeneity was ubiquitous, including baseline pathogen, treatment and patient characteristics. Conclusion: Limited and heterogeneous data identified make the use of NMA to compare novel antibacterial agents impractical and likely unreliable.

Candida nivariensis Urinary Tract Infection in an Extremely Low-Birth-Weight Neonate

2018 ◽  
Vol 15 (01) ◽  
pp. 057-060
Author(s):  
Katherine M. Malloy ◽  
Kristen R. Nichols ◽  
Anna E. Thomas
Keyword(s):  
Urinary Tract Infection ◽  
Birth Weight ◽  
Urinary Tract ◽  
Tract Infection ◽  
Low Birth Weight ◽  
Pediatric Population ◽  
Extremely Low Birth Weight ◽  
Birth Weight Neonate ◽  
Amphotericin B Deoxycholate ◽  
Candida Nivariensis

AbstractWe report on the diagnosis and treatment of a Candida nivariensis urinary tract infection in an extremely low-birth-weight neonate. The isolate was identified by MALDI-TOF technology and is the first known report of C. nivariensis in the neonatal or pediatric population. Treatment was initiated with amphotericin B deoxycholate and later completed with intravenous fluconazole following susceptibility results.

Urinary tract infection in very low birth weight preterm infants

2003 ◽  
Vol 22 (5) ◽  
pp. 426-429 ◽  
Author(s):  
SOFIA BAUER ◽  
ALON ELIAKIM ◽  
AVISHALOM POMERANZ ◽  
RIVKA REGEV ◽  
ITA LITMANOVITS ◽  
...  
Keyword(s):  
Urinary Tract Infection ◽  
Birth Weight ◽  
Urinary Tract ◽  
Tract Infection ◽  
Low Birth Weight ◽  
Preterm Infants ◽  
Very Low Birth Weight

Suprapubic Aspiration of Urine in Very Low Birth Weight Infants

PEDIATRICS ◽  
1993 ◽  
Vol 92 (3) ◽  
pp. 457-459
Author(s):  
BRIAN M. BARKEMEYER
Keyword(s):  
Urinary Tract Infection ◽  
Birth Weight ◽  
Urinary Tract ◽  
Tract Infection ◽  
Low Birth Weight ◽  
Preterm Infants ◽  
Very Low Birth Weight ◽  
Late Onset ◽  
Low Birth Weight Infants ◽  
Term Infants

The incidence of urinary tract infection in the neonatal period is higher in preterm than in term infants.1 These are typically late-onset infections occurring after 72 hours of age.2 Because the signs of urinary tract infection in neonates are nonspecific, a safe and effective way of sampling urine for culture such as suprapubic aspiration is essential. Although previous studies have demonstrated the efficacy of this procedure in term and preterm infants, the preterm infants studied previously were undoubtedly larger than those very low birth weight infants cared for in today's neonatal intensive care units, inasmuch as survival rates for these small infants have increased.1,3

scholarly journals Efficacy and safety of quinolones for the treatment of uncomplicated urinary tract infections in women: a network meta-analysis

2019 ◽  
Author(s):  
Alejandro G Gonzalez-Garay ◽  
Liliana Velasco-Hidalgo ◽  
Eric Ochoa-Hein ◽  
Roberto Rivera-Luna
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Adverse Events ◽  
Treatment Duration ◽  
Meta Analysis ◽  
Uncomplicated Urinary Tract Infection ◽  
Efficacy And Safety ◽  
Menopausal Women ◽  
Tract Infections

Abstract Background Uncomplicated urinary tract infection is considered an infection that occurs in healthy individuals who have a normal urinary tract, representing 5% of all annual medical visits. Several quinolones are available as second-line agents for treatment; however, we do not know which is the best antibiotic scheme for urinary tract infection; therefore, we conducted a network meta-analysis to hierarchize each quinolone according to its efficacy and safety. Methods MEDLINE, EMBASE and other databases were subjected to non-language-restricted searches up to 2018 for trials that included women treated with quinolones for uncomplicated urinary tract infection. Bias in the trials was assessed by two reviewers; the Cochrane Collaboration tool was used to analyze clinical and bacteriological remission, relapse, resistance, and adverse events. For direct comparisons, we obtained risk ratios and 95% confidence intervals by applying a fixed events model using Tau2 and Q2 tests to calculate the heterogeneity using trimethoprim/sulfamethoxazole as the common comparator across studies. For the network meta-analysis, we analyzed the indirect comparisons by Bucher's method. The results were summarized in a correlation matrix. Results We included 18 trials with 8765 women. For pre-menopausal women and treatment duration <3 days, norfloxacin and ofloxacin had a 57% of probability for achieving remission but with an 83% frequency of adverse events. For post-menopausal women, ciprofloxacin and ofloxacin were 82% more effective for remission with an 49% frequency of adverse events compared with other types of quinolones. Conclusions Compared with other quinolones, ofloxacin (200 mg) was more effective for remission, although with a high probability of adverse events; however, norfloxacin (400 mg) could be an alternative in treatment, due to it low probability of adverse events; even though additional trials are needed to confirm our findings, especially in treatment duration exceeds 3 days. PROSPERO registration CRD42015025886

scholarly journals The prevalence of urinary tract infections in type 2 diabetic patients: a systematic review and meta-analysis

2020 ◽  
Author(s):  
Aliakbar Vaisi-Raygani ◽  
Nader Salari ◽  
Mohammad mahdi Karami ◽  
Shadi Bokaee ◽  
Masoud Mohammadi ◽  
...  
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Urinary Tract Infections ◽  
Meta Analysis ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Tract Infections ◽  
Type 2 Diabetic

Abstract Background Urinary tract infection is the most common infection in type 2 diabetic patients. Various studies have reported different outbreaks of urinary tract infections in type 2 diabetic patients, Therefore, the present study aimed to determine the prevalence of urinary tract infections in type 2 diabetic patients during a systematic review and meta-analysis to open windows to more detailed programs to reduce the incidence of urinary tract infections in type 2 diabetic patients. Methods In this study, systematic review and Meta-Analysis of study data related to the prevalence of urinary tract infection in type 2 diabetic patients using keywords including: Type 2 diabetes, urinary tract infection, diabetes, prevalence, Meta-Analysis and their English equivalents in SID, MagIran, IranMedex, IranDoc, Google scholar, Cochrane, Embase, Science Direct, Scopus, PubMed and Web of Science (ISI) databases over the years It was mined from 1993 to 2020.In order to perform the analysis of qualified studies, the model of random effects was used and the inconsistency of studies with I2 index was investigated. Data analysis was performed with Comprehensive Meta-Analysis (version 2). Results In a study of 15 studies with a sample size of 827,948 in Meta-Analysis, the overall prevalence of urinary tract infection in patients with type 2 diabetes was 11.5% (95% confidence interval: 7.8–16.7%). Increasing the number of years of research, the prevalence of urinary tract infections in diabetic patients of the Iranian type increased (P = 0.000), and with increasing age of participants (P = 0.000) and also with increasing sample size (P = 0.000), this prevalence decreased. Conclusion The results of this study show that urinary tract infections are highly prevalent in patients with type 2 diabetes, so due to the growing prevalence of diabetes and its complications such as urinary tract infections, the need for appropriate screening programs and health care policies is becoming more apparent.

Risk Factors in Diabetes and Pregnant Women with Urinary Tract Infections Compared to Younger Aged Female.

2018 ◽  
Vol 1 (3) ◽  
pp. 26-38
Author(s):  
Abdulghani Mohamed Alsamarai ◽  
Shler Ali Khorshed
Keyword(s):  
Risk Factors ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Pregnant Women ◽  
Female Student ◽  
Mean Value ◽  
Infected Female ◽  
Significant Difference ◽  
Tract Infections

Background: Urinary tract infection is common with health impact in women and characterised by failure to treatment and recurrent episodes. Aim: This study was conducted to determine the risk factors for the development of urinary tract infection in diabetic and pregnant women in comparison to student female. Materials and methods: A prospective cross-sectional study conducted during the period from 1st of June 2015 to the end of January 2016. The population included in the study are 563 women, of them 425 were outpatients, and 138 were inpatients. Their age range between 18 and 80 years, with a mean age of 33.59±15.29 years. Urine samples collected and cultured on blood agar and MacConkey agar by spread plate technique. Bacterial colonies with different morphology were selected, purified and identified according to their biochemical characteristics using conventional standard methods. Results: In diabetic women, there were no significant difference in mean age and BMI values between culture positive and culture negative groups. However, pus cell mean scale was significantly higher [P=0.000] in women with urinary tract infection [1.76±1.25] than in those with negative culture [0.69±1.00]. In pregnant women, BMI mean value was significantly [P=0.013] lower in pregnant women with UTI [26.14] as compared to those without infection [26.99]. Pus cell scale mean value was significantly [P=0.000] higher in pregnant women with UTI [1.55] than women with negative UTI [0.85]. While there was no significant difference in mean age between UTI positive and negative pregnant women. In female student, there was a significant difference between UTI infected and non-infected in mean age [P=0.041] and pus cell scale [P=0.000]. However, BMI was not significantly different between infected and non-infected female student. Other risk factors association are variables in the 3 groups when analysed using X2, while AUC and OR show different trends of association between risk factors and UTI. Conclusion: BMI, pus cell scale, child number, delivery method, operation history and hospital setting were significantly associated with culture positivity in the 3 studied groups as determined by AUC. While OR confirmed association with pus sale scale in the 3 groups.

Sign in / Sign up

Export Citation Format

Share Document