scholarly journals Maternal Urinary Tract Infection: Is It Associated With Neonatal Urinary Tract Infection?

2021 ◽  
Author(s):  
Huseyin Bilgin ◽  
Emine Esin Yalinbas ◽  
Ilknur Elifoglu ◽  
Sahinde Atlanoglu
Keyword(s):  
Urinary Tract Infection ◽  
Birth Weight ◽  
Urinary Tract ◽  
Tract Infection ◽  
Low Birth Weight ◽  
Preterm Delivery ◽  
Control Group ◽  
Study Group ◽  
Infection Frequency ◽  
Tract Infections

Objective: Maternal urinary tract infection is associated with intrauterine growth restriction, preterm delivery and low birth weight. The purpose of this study was to evaluate whether maternal urinary tract infection is related to neonatal urinary tract infection. Materials and methods: The present prospective study included 230 singleton neonates. The participants were divided into two groups based on in utero exposure to maternal urinary tract infections. The study group (exposure to maternal urinary tract infection) included 115 neonates and the control group (without exposure to maternal urinary tract infection) included 115 healthy neonates. Physical examination, urinalysis, urine culture and urinary system ultrasonography were carried out for all neonates. Results: There were 153 deliveries by cesarean section and 77 vaginal births. There was no statistically significant difference between the groups in terms of gender distribution, maternal age, birth weight, mode of delivery, gravida and gestational age. Although the difference was not significant, the incidence of low birth weight and preterm delivery were higher in the study group in comparison to that in the control group. There was a statistically significant higher rate of neonatal urinary tract infection in the study group compared with control group (25.2% vs. 7.8%, p<0.001). The most commonly discovered pathogens were Escherichia coli, followed by Klebsiella spp., Proteus spp., and Serratia spp. in the study group. Conclusion: The results of this study showed that the presence of maternal urinary tract infection may contribute to increased urinary tract infection frequency in the neonatal period. Neonates at risk for a urinary tract infection should be regularly monitored due to nonspecific clinical presentation.

scholarly journals Factors Affecting Prevalence of Urinary Tract Infection in Neo-nates with Unexplained Hyperbilirubinemia: A Systematic Re-view and Meta-Analysis Study in Iran

2021 ◽  
Author(s):  
Fahimeh Bagheri Amiri ◽  
Sanaz Tavasoli ◽  
Nasrin Borumandnia ◽  
Maryam Taheri
Keyword(s):  
Urinary Tract Infection ◽  
Birth Weight ◽  
Urinary Tract ◽  
Tract Infection ◽  
Low Birth Weight ◽  
Meta Analysis ◽  
Female Gender ◽  
Normal Birth Weight ◽  
Normal Birth ◽  
Tract Infections

Background: The prevalence and risk factors of urinary tract infection (UTI) in neonates with unexplained hyperbilirubinemia are not studied thoroughly. Since the prevalence of UTI is highly variable in different areas and countries, this study aimed to review the existing data of Iranian neonates with UTI presented with unexplained hyperbilirubinemia. Methods: This study is a meta-analysis of Iranian newborns with unexplained hyperbilirubinemia. We identified all studies indexed in international (Web of Science, PubMed, Scopus, Google Scholar) and national (Science Information Database, Magiran) databases from 2000-2018. Search terms included: Urinary Tract Infections OR UTI AND urine OR culture OR microbio, jaundice OR icter OR hyperbili, AND Iran. Results: Overall, 4210 neonates from 17 studies were included. The pooled prevalence of UTI in neonates with unexplained hyperbilirubinemia was 6.81% (95% CI: 4.86-8.77). Considering the subgroups analyses; the prevalence of UTI was higher in the prolonged vs. not-prolonged state (8.34% vs. 4.00%), low birth weight vs. normal birth weight (7.81% vs. 4.51%), and exclusive vs. non-exclusive breastfeeding (8.84% vs. 4.72%). Male gender and low birth weight increased the risk of UTI about two times compared to the female gender and normal birth weight, respectively. The results of the analyses in neonates with unconjugated hyperbilirubinemia also showed the above-mentioned subgroup differences.  

Candida nivariensis Urinary Tract Infection in an Extremely Low-Birth-Weight Neonate

2018 ◽  
Vol 15 (01) ◽  
pp. 057-060
Author(s):  
Katherine M. Malloy ◽  
Kristen R. Nichols ◽  
Anna E. Thomas
Keyword(s):  
Urinary Tract Infection ◽  
Birth Weight ◽  
Urinary Tract ◽  
Tract Infection ◽  
Low Birth Weight ◽  
Pediatric Population ◽  
Extremely Low Birth Weight ◽  
Birth Weight Neonate ◽  
Amphotericin B Deoxycholate ◽  
Candida Nivariensis

AbstractWe report on the diagnosis and treatment of a Candida nivariensis urinary tract infection in an extremely low-birth-weight neonate. The isolate was identified by MALDI-TOF technology and is the first known report of C. nivariensis in the neonatal or pediatric population. Treatment was initiated with amphotericin B deoxycholate and later completed with intravenous fluconazole following susceptibility results.

Evaluation of Serum Metalloprotinase-9 (MMP-9) in Iraqi Men with urinary tract infection

2017 ◽  
Vol 6 (12) ◽  
pp. 5558
Author(s):  
Hanan D. Abbas
Keyword(s):  
United States ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
United States Of America ◽  
Prognostic Biomarker ◽  
The United States ◽  
Control Group ◽  
Strong Relation ◽  
Tract Infections

Objective: The inflammation of the urinary tract and its various causes is one of the important diseases, which neglect and non-treatment lead to many amplifications, therefore, many countries including the United States of America has given urinary tract infection ″UTI″ a great interest. Since the disease is sometimes without obvious symptoms and because of research lacking that are using MMP-9. The aim of this work is to study the alterations in the Metalloprotinase-9 (MMP-9), and its role in pathogenicity of urinary tract infections ″UTI″ in serum of men who are initially diagnosed with this disease.Methods: This study was applied in educational Alsader hospital in Najaf city by using Enzyme Linked Immuno Sorbent Assay (ELISA) on serum taken from 42 men infected with UTI, and other 38 healthy considered as a control group to detect MMP-9.Data analysis: SPSS computerizing system has been used for statistically analysis of data. Results: The results revealed a highly significant (P<0. 05) level of ″MMP-9″in serum of patients in comparison with the control group. The result also demonstrated the strong relation between MMP-9 and other parameters such as age and smoking.Conclusion: It was concluded from the results of the present study thatMetalloprotinase-9″MMP-9″ was good prognostic biomarker for ″UTI″ in men, and these results significantly correlate with the early stages of disease.Recommendation: 1-It may be recommended that using MMP-9 to predict and diagnosis the urinary tract infection. 2-It may be also recommended to measure MMP-9 in women to establish its role in this disease 

scholarly journals COMPARATION OF EFFECTIVENESS OF NORMAL SALINE AND 10% POVIDONE IODINE IN PERIURETHRAL CLEANING

2016 ◽  
Vol 1 (1) ◽  
Author(s):  
Awaluddin Awaluddin
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Normal Saline ◽  
Povidone Iodine ◽  
Urinary Catheter ◽  
Infection Risk ◽  
Control Group ◽  
Tract Infections ◽  
Indwelling Urinary Catheter

Currently, urinary tract infection incidence in patients with indwelling urinary catheter ranges between 10-80%. They are at risk for other problems that can cause death. Appropriate action is required to decrease urinary tract infection risk by periurethral area cleaning. The aim of this study is to analyze the differences of the effectiveness of the use of normal saline and 10% povidone iodine for periurethral area cleaning in decreasing urinary tract infection risk. Research methods uses experimental design with the population of patients who used indwelling urinary catheter. Samples were obtained by consecutive and allocation by randomization which were divided into 2 groups, each group were 17 respondents. In the treatment group, periurethral area was cleaned with normal saline and in the control group with 10% povidone iodine. Urinary tract infection risk assessment was carried out by the leukocyte esterase dipstick test at 8 hours after insertion. The results indicate that the incidence of urinary tract infections risk in the group using normal saline smaller than 10% povidone iodine  with a comparison of 1:1.3. Number need to treat in this study was 6. The conclusion of this study is normal saline is more effective in reducing urinary tract infection risk.

scholarly journals COMPARATION OF EFFECTIVENESS OF NORMAL SALINE AND 10% POVIDONE IODINE IN PERIURETHRAL CLEANING

2016 ◽  
Vol 1 (1) ◽  
Author(s):  
Awaluddin Awaluddin
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Normal Saline ◽  
Povidone Iodine ◽  
Urinary Catheter ◽  
Infection Risk ◽  
Control Group ◽  
Tract Infections ◽  
Indwelling Urinary Catheter

Currently, urinary tract infection incidence in patients with indwelling urinary catheter ranges between 10-80%. They are at risk for other problems that can cause death. Appropriate action is required to decrease urinary tract infection risk by periurethral area cleaning. The aim of this study is to analyze the differences of the effectiveness of the use of normal saline and 10% povidone iodine for periurethral area cleaning in decreasing urinary tract infection risk. Research methods uses experimental design with the population of patients who used indwelling urinary catheter. Samples were obtained by consecutive and allocation by randomization which were divided into 2 groups, each group were 17 respondents. In the treatment group, periurethral area was cleaned with normal saline and in the control group with 10% povidone iodine. Urinary tract infection risk assessment was carried out by the leukocyte esterase dipstick test at 8 hours after insertion. The results indicate that the incidence of urinary tract infections risk in the group using normal saline smaller than 10% povidone iodine  with a comparison of 1:1.3. Number need to treat in this study was 6. The conclusion of this study is normal saline is more effective in reducing urinary tract infection risk.

scholarly journals Faecal Escherichia coli from patients with E. coli urinary tract infection and healthy controls who have never had a urinary tract infection

2014 ◽  
Vol 63 (4) ◽  
pp. 582-589 ◽  
Author(s):  
Karen L. Nielsen ◽  
Pia Dynesen ◽  
Preben Larsen ◽  
Niels Frimodt-Møller
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract Infection ◽  
Multidrug Resistance ◽  
Urinary Tract ◽  
Tract Infection ◽  
Control Group ◽  
Healthy Controls ◽  
Faecal Flora ◽  
E Coli ◽  
Tract Infections

Urinary tract infections (UTIs) are primarily caused by Escherichia coli with the patient’s own faecal flora acting as a reservoir for the infecting E. coli. Here we sought to characterize the E. coli faecal flora of UTI patients and healthy controls who had never had a UTI. Up to 20 E. coli colonies from each rectal swab were random amplified polymorphic DNA (RAPD) typed for clonality, dominance in the sample and correlation to the infecting UTI isolate in patients. Each distinct clone was phylotyped and tested for antimicrobial susceptibility. Eighty-seven per cent of the UTI patients carried the infecting strain in their faecal flora, and faecal clones causing UTI were more often dominant in the faecal flora. Patients had a larger diversity of E. coli in their gut flora by carrying more unique E. coli clones compared to controls, and patient faecal clones were more often associated with multidrug resistance compared to controls. We found a similar phylotype distribution of faecal clones from UTI patients and healthy controls, including a large proportion of B2 isolates in the control group. Faecal-UTI isolates from patients were more often associated with multidrug resistance compared to faecal-only clones, indicating a link between UTI virulence and antimicrobial resistance. Intake of any antibiotic less than 6 months prior to inclusion in the experiment occurred significantly more in patients with UTI than in controls. In contrast, presence of an intrauterine device was significantly more common in controls indicating a protective effect against UTI. In conclusion, healthy controls have a large proportion of potentially pathogenic E. coli phylotypes in their faecal flora without this causing infection.

Urinary tract infection in very low birth weight preterm infants

2003 ◽  
Vol 22 (5) ◽  
pp. 426-429 ◽  
Author(s):  
SOFIA BAUER ◽  
ALON ELIAKIM ◽  
AVISHALOM POMERANZ ◽  
RIVKA REGEV ◽  
ITA LITMANOVITS ◽  
...  
Keyword(s):  
Urinary Tract Infection ◽  
Birth Weight ◽  
Urinary Tract ◽  
Tract Infection ◽  
Low Birth Weight ◽  
Preterm Infants ◽  
Very Low Birth Weight

scholarly journals Recurrent Urinary Tract Infections Risk Factors in Patients with Primary Vesicoureteral Reflux

2021 ◽  
Vol 15 (7) ◽  
pp. 1890-1893
Author(s):  
Sardar Khan ◽  
Sajjad Hussain ◽  
Zahir Said ◽  
Ihsan Ul Haq ◽  
Habib U Rehman ◽  
...  
Keyword(s):  
Risk Factors ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Vesicoureteral Reflux ◽  
Control Group ◽  
Renal Unit ◽  
Group I ◽  
Therapeutic Decisions ◽  
Tract Infections

Background: Knowing the risk of recurrence of urinary tract infection (UTI) in vesicoureteral reflux (VUR) can assist clinicians to sort therapeutic decisions. The current study's aim was to assess the association of UTI in VUR. Additionally, UTI recurrence might be predicted by the risk score. Materials and Methods: This case-control study was carried out on 123 children at department of Paediatric, Saidu Group of Teaching Hospitals, Swat for the duration of one year from 1st July 2020 to 30thJune 2021. Out of 123 children, the group-I had 57 children with documented previous UTIs history while group-II had 66 children with no previous UTIs and was referred to as a control group. All the patients were VUR diagnosed and were thoroughly followed up at a Renal Unit of single tertiary. UTI recurrence was referred to more than one follow-up episode. A regression model was used for independent variables identification regarding UTI recurrence. . A questionnaire on bowel habits was provided to the parents. The abdominal plain film was evaluated by the observer and recorded on the documented scoring system. The constipation history was compared with the radiological and symptomatic scores. Organism single species with > 105/ml count in a single midstream catch of urine sample was reflected as UTI evidence. Result: Out of 123 children, 88 (71.5%) were females while 35 (28.5%) were male. A total of 123 children had been investigated for UTI complaints. After the multivariable analysis adjustment, five recurrent UTIs predictor variables were the clinical presentation of UTI, female gender, reflux several grades, age less than 6 months, and syndrome dysfunction elimination. The UTIs recurrence risk factors were classified as high, medium, and low with prevalence 52 (42%), 41 (34%), and 30 (24%) respectively. The prevalence of UTIs rate per person-month was 10.9 (95% CI, 9.8, 12.7), 8.2 (95% CI, 6.7, 9.1) for medium, and 5.2 (95% CI, 3.3, 5.5) for the low-risk group. Conclusion: The formulation of therapeutic strategies can be done based on prediction model for UTIs recurrence besides early detection of morbidity long-term risk for the patients. Keywords: Vesicoureteral reflux, Urinary tract infection, Dysfunctional voiding, Constipation

scholarly journals Study of urinary tract infection in febrile children below 2 years of age

2018 ◽  
Vol 6 (11) ◽  
pp. 3657
Author(s):  
P. L. Prasad ◽  
Aditi Gupta ◽  
Gaurav Mukhija
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Infants And Children ◽  
Control Group ◽  
Case Group ◽  
Study Group ◽  
Age Group ◽  
Group A ◽  
Age And Sex

Background: Urinary Tract Infection (UTI) in age group 0-2 years is of special interest to clinicians and assumes importance as it can lead to pyelonephritis, septicemia or meningitis in newborn and infants which can be fatal. This study is undertaken to calculate the incidence of UTI in febrile children less than 2 years of age and to compare the incidence with afebrile children visiting pediatric OPD and IPD of SRMS IMS.Methods: Two hundred and two febrile infants and children constituted the case group. A control group, constituted of one hundred and ninety seven, age and sex matched afebrile patients from IPD/OPD. Urine collected was subjected to microscopic and microbiological examination.Results: There were ten cases of UTI in the study group and none was found in the control group. The overall incidence of UTI in febrile infants and children less than 2 years was 4.95%. Infants and children admitted with diagnosis other than UTI were screened for UTI and it was found in 4.6% of the cases whereas babies admitted without definite focus had an incidence of 5.56% which signifies that UTI should be screened in all febrile infants irrespective of their other etiologies of fever. Maternal illiteracy was found to be statistically significant as 5 out of 10 cases of UTI were associated with illiterate mothers.Conclusions: In the present study, we found that the screening of the infants for identification of UTI is useful irrespective of the presence of other etiologies thus early initiation of treatment prevents most complications of UTI, so the importance of early diagnosis cannot be overemphasized.

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