scholarly journals Cadmium Level Status in Iranian Breast Milk: A Systematic Review

Author(s):  
Ali Ghaffarian Bahraman ◽  
Mohsen Rezaeian

Introduction: Due to the lack of a systematic review on cadmium status in breast milk of Iranian mothers, this study was designed to evaluate the published articles on factors affecting the exposure and the levels of cadmium in breast milk. Methods: In this study, English and Farsi electronic databases, including PubMed, Scopus, Google Scholar, Web of Science, Magiran, Iran Medex and SID were comprehensively searched for papers published from July 2009 until May 2021. The PRISMA guidelines for reporting systematic reviews were followed for screening and reviewing the processes involved in this study. Results: From 102 articles found in the initial search, 9 studies were included in systematic review. The highest mean cadmium concentration was related to milk samples collected from Kerman City. Among study factors, the exposure to cigarette smoke, living near industrial centers and maternal nutrition had a significant effect on increasing the concentration of cadmium in breast milk. Conclusion: Further studies are demanded to obtain more comprehensive and reliable results on the status of cadmium in breast milk of Iranian mothers.

2020 ◽  
Vol 8 ◽  
Author(s):  
Carina Rodrigues ◽  
Inês Baía ◽  
Rosa Domingues ◽  
Henrique Barros

Background: The COVID-19 pandemic is an emerging concern regarding the potential adverse effects during pregnancy. This study reviews knowledge on the impact of COVID-19 on pregnancy and describes the outcome of published cases of pregnant women diagnosed with COVID-19.Methods: Searches were conducted in PubMed®, Scopus®, Web of Science®, and MedRxiv® up to 26th June 2020, using PRISMA standards, to identify original published studies describing pregnant women at any gestational age diagnosed COVID-19. There were no date or language restrictions on the search. All identified studies were included irrespective of assumptions on study quality.Results: We identified 161 original studies reporting 3,985 cases of pregnant women with COVID-19 (1,007 discharged while pregnant). The 2,059 published cases with pregnancy outcomes resulted in 42 abortions, 21 stillbirths, and 2,015 live births. Preterm birth occurred in 23% of cases. Around 6% of pregnant women required admission to an intensive care unit and 28 died. There were 10 neonatal deaths. From the 163 cases with amniotic fluid, placenta, and/or cord blood analyzed for the SARS-CoV-2 virus, 10 were positive. Sixty-one newborns were positive for SARS-CoV-2. Four breast milk samples from 92 cases showed evidence of SARS-CoV-2.Conclusion: Emerging evidence suggests that vertical transmission is possible, however, there is still a limited number of reported cases with intrapartum samples. Information, counseling and adequate monitoring are essential to prevent and manage adverse effects of SARS-CoV-2 infection during pregnancy.


2019 ◽  
Author(s):  
Khaled I. A. Amrouni ◽  
Ruzaini A. Arshah ◽  
Alaa J. Kadi

Information and communication technologies (ICT) have been implemented mainly in government organizations, where e-government has become prevalent. The previous research focuses mostly on e-government adoption from the perspective of citizens. However, there is a scarcity of research conducted from the viewpoint of the employee. This study tried to identify and predict the factors that influence an employee to adopt technology implemented at the workplace by focusing on acceptance technology theories. The unified theory of acceptance and usage of technology (UTAUT) and Task-technology fit (TTF) using relevant findings in this review. The attempt to conduct a comprehensive explanation and analysis of the existing literature up to 2018, to understand the current situation of e-government implementation. Reviewing procedures were done by reviewing articles on e-government and related work by using indexing databases “web of science & Scopus. Finally, the results of this paper are the factors that make employees directly or indirectly adopt e-government.


Author(s):  
Jean-Michel HASCOET ◽  
Martine CHAUVIN ◽  
Christine PIERRET ◽  
Sebastien SKWERES ◽  
Louis-dominique VAN EGROO ◽  
...  

(1) Background: Premature infants require mothers’ milk fortification to meet nutrition needs, but breast milk composition may be variable leading to a risk of inadequate nutrition. We aimed at determining factors influencing mothers’ milk macronutrients. (2) Methods: Milk samples were analyzed for the first 5 weeks after premature delivery, by infrared spectroscopy. Mothers’ nutritional intake data were obtained during standardized interviews with dieticians then analyzed with reference software. (3) Results: Composition of 367 milk samples from 81 mothers was (Median [range]g/100mL): Carbohydrates 6.8[4.4-7.3], lipids 3.4[1.3-6.4], proteins 1.3[0.1-3.1]. There was a relationship of milk composition with mothers’ carbohydrates intake only (r=0.164; p<.01). Postnatal age was correlated with milk proteins (r=-0.505 p<.001) & carbohydrates (r=+0.202, p<.001). Multiple linear regression analyses showed (coefficient) a relationship between milk proteins r=0.547 and postnatal age (-0.028), carbohydrates intake (+0.449) and the absence of maturation (-0.066); and between milk lipids r=0.295 and carbohydrates intake (+1.279) and smoking (-0.557). Finally, between milk carbohydrates concentration r=0.266 and postnatal age (+0.012) and smoking (-0.167). (4) Conclusions: Variability of mothers’ milk composition is differentially associated for each macronutrient with maternal carbohydrates intake, antenatal steroids, smoking, and postnatal age. Improvement in milk composition could be achieved by modification of these related factors.


2021 ◽  
Vol 11 (20) ◽  
pp. 9400
Author(s):  
Georgia Nikolopoulou ◽  
Theofania Tsironi ◽  
Panagiotis Halvatsiotis ◽  
Ekaterini Petropoulou ◽  
Nikolaos Genaris ◽  
...  

Breast milk has been reported as a bacteria source that affects infant gut microbiota development. The present study utilizes a realtime PCR method to identify Lactobacillus and Bifidobacterium spp. in the breast milk of healthy women and attempts to identify factors affecting those human milk bacteria. Breast milk samples—both colostrum and mature milk—of 100 healthy women, were collected in Greece along with data about the demographic factors and nutritional habits of the volunteers. The colostrum samples were found to have higher percentages of either Bifidobacterium or Lactobacillus (76.9% and 48.6%, respectively) compared to the mature milk samples. For younger women, aged from 18 to 29 years, and women from rural areas, bacteria were detected in higher incidence than for older groups and women in urban areas, respectively. Moreover, for high-BMI women, bacteria were detected in lower incidence than for those with normal BMI. Probiotic supplements did not affect the composition of the breast milk-identified bacteria. Various factors such as lactation stage, maternal age, maternal weight, and residential location may contribute to the presence of those species in human milk. RT PCR has significant potential for the microbiological analysis of human milk.


Nutrients ◽  
2019 ◽  
Vol 11 (2) ◽  
pp. 366 ◽  
Author(s):  
Jean-Michel Hascoët ◽  
Martine Chauvin ◽  
Christine Pierret ◽  
Sébastien Skweres ◽  
Louis-Dominique Van Egroo ◽  
...  

(1) Background: Premature infants require mothers’ milk fortification to meet nutrition needs, but breast milk composition may be variable, leading to the risk of inadequate nutrition. We aimed at determining the factors influencing mothers’ milk macronutrients. (2) Methods: Milk samples were analyzed for the first five weeks after premature delivery by infrared spectroscopy. Mothers’ nutritional intake data were obtained during standardized interviews with dieticians, and then analyzed with reference software. (3) Results: The composition of 367 milk samples from 81 mothers was (median (range) g/100 mL): carbohydrates 6.8 (4.4–7.3), lipids 3.4 (1.3–6.4), proteins 1.3 (0.1–3.1). There was a relationship between milk composition and mothers’ carbohydrates intake only (r = 0.164; p < 0.01). Postnatal age was correlated with milk proteins (r = −0.505; p < 0.001) and carbohydrates (r = +0.202, p < 0.001). Multiple linear regression analyses showed (coefficient) a relationship between milk proteins r = 0.547 and postnatal age (−0.028), carbohydrate intake (+0.449), and the absence of maturation (−0.066); associations were also found among milk lipids r = 0.295, carbohydrate intake (+1.279), and smoking (−0.557). Finally, there was a relationship among the concentration of milk carbohydrates r = 0.266, postnatal age (+0.012), and smoking (−0.167). (4) Conclusions: The variability of mothers’ milk composition is differentially associated for each macronutrient with maternal carbohydrate intake, antenatal steroids, smoking, and postnatal age. Improvement in milk composition could be achieved by the modification of these related factors.


2016 ◽  
Vol 104 (3) ◽  
pp. 646-662 ◽  
Author(s):  
Francesca Bravi ◽  
Frank Wiens ◽  
Adriano Decarli ◽  
Alessia Dal Pont ◽  
Carlo Agostoni ◽  
...  

2019 ◽  
Vol 8 ◽  
pp. e1236
Author(s):  
Solmaz Azimzadeh ◽  
Jafar Sadegh Tabrizi ◽  
Shirin Nosratnejad ◽  
Mostafa Farahbakhsh ◽  
Saber Azami Aghdash ◽  
...  

Utilization is one of the dimensions of equity in health systems. Identifying the factors affecting utilization of health services can be helpful for interventional purposes. This study systematically reviewed the factors affecting the utilization of inpatient, outpatient, diagnostic, and pharmaceutical services. This systematic review was conducted between 2016 and 2017. The search was performed using keywords based on MeSH in valid databases such as Scopus, Embase, ProQuest, ScienceDirect, PubMed, and Web of Science in the fields of title, abstract, and keyword. Related papers published from 2000 to 2017 were searched. First, the retrieved studies were screened and checked for quality; then, the useful data were extracted and analyzed. Out of the 1178 retrieved publications, 20 studies were included in the final analysis. The identified factors were categorized into 5 areas, including demographic (4 items), socioeconomic (13 items), health services–related (13 items), health status–related (7 items), and health insurance–related factors (2 items), and reported. The findings of this study can be a useful source and a comprehensive body of evidence on the utilization of health services. The results can be used by the policy makers and managers in designing interventions for changing the utilization patterns of health services. [GMJ.2019;8:e1236]


2021 ◽  
Vol 5 (Supplement_2) ◽  
pp. 724-724
Author(s):  
Xiaokun Cai ◽  
Yingyi Mao ◽  
Lou Zeru ◽  
Hanxiao Sun ◽  
Yanrong Zhao ◽  
...  

Abstract Objectives The study aimed to investigate the levels of RRR-α-tocopherol and carotenoids in maternal blood, cord blood and breast milk samples of different lactation stages from healthy Chinese mothers and to explore their associations with social demographical characteristics. Methods The study was part of a MUAI study (Maternal Nutrition and Infant Investigation, ChiCTR1800015387). Samples collection Healthy lactating mothers (aged 20–35 year) with single, full-term delivery were recruited in Tianjin city. Maternal blood, cord blood, colostrum, transitional milk and mature milk samples were collected. Sample analysis The levels of tocopherols and carotenoids (lutein, zeaxanthin, β-cryptoxanthin, β-carotene,lycopene) were determined by HPLC. The compositions of α-tocopherol stereoisomers were determined by chiral HPLC. Results Maternal blood plasma contained higher α-tocopherol level than cord blood plasma and breast milk samples. In breast milk samples, the levels of α-tocopherol reduced with lactation stages for about three times. Even though the levels of α-tocopherol varied in plasma and breast milk, RRR-α-tocopherol (RRR) were predominant in all samples, accounting for 83%∼90% of α-tocopherol. The results suggestted RRR was preferred stereoisomers for maternal and newborn. Carotenoids were also more abundant in maternal blood plasma than in cord blood plasma and breast milk samples. The total carotenoids level in maternal blood plasma was about 8 times higher than cord blood plasma and 2.5 times of colostrum. The level of total carotenoids decreased with the lactation stages due to the dramatically dropped of lycopene and β-carotene. In contrast, lutein level remained stable in breast milk and was the most abundant carotenoids in transitional milk, mature milk and blood plasma, suggesting that fetus and infant had continuous demand for lutein. The levels of carotenoids and RRR in maternal and cord blood plasma were related to parity, pre-pregnancy and prenatal BMI. The levels of carotenoids and RRR in breast milk samples were correlated with cord plasma. Conclusions RRR- α-tocopherol and lutein were the most abundant α-tocopherol and carotenoids in Chinese cord blood plasma and breast milk, suggesting that they may play more important roles in early life. Funding Sources This study was funded by Abbott Nutrition R&D Centre, Shanghai, China.


2018 ◽  
Vol 12 (1) ◽  
pp. 133-146
Author(s):  
Li’izza Diana Manzil

One sign of the rapidly growing world of medical science is its success in making one discovery about Deoxrybo Nucleid Acid (DNA). Islam does not prohibit the practice of DNA identification because it can be used in determining the legal status of relative relationships and related marital prohibitions among families because of the similarity of DNA genes between parents and their children. In Islam marriage prohibition can also occur between brothers and sisters. DNA identification can be done between siblings as a result of the presence of gene elements in breast milk. In addition, breast milk can also develop bone and grow meat if breastfeeding at least five times suction. But the results of DNA tests conducted between siblings cannot be more accurate if done to find relationships of parents and children. From this it clearly proves that Islamic medicine has an urgent value to Islamic law. This can be seen from one of its axiology in determining the status of brotherhood.


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