Comparative Evaluation of the Efficacy of Ice Cubes Versus Sodium Bicarbonate Mouthwash both as Prophylactic Measure and as Treatment of Oral Mucositis Induced by Systemic Anticancer Therapies

2020 ◽  
Author(s):  
Bilal Ismael Hamad Ameen ◽  
Ali Fakhree Alzubaidee ◽  
Sarkawt Majid
Keyword(s):  
Sodium Bicarbonate ◽  
Teaching Hospital ◽  
Oral Mucositis ◽  
Comparative Evaluation ◽  
Preventive Measure ◽  
Prophylactic Measure ◽  
Before And After ◽  
Two Measures ◽  
Treatment Measure

Oral mucositis is a complication of systemic anticancer therapies. This study aimed at investigating the use of ice cubes and sodium bicarbonate mouthwash as a preventive and a treatment measure for oral mucositis in patients receiving systemic anticancer therapies. The two measures were given to 50 patients, 24 of whom already had oral mucositis at Oncology Department in Rizgary Teaching Hospital in Erbil/ Iraq. Patients’ grades for oral mucositis were recorded before and after receiving the two measures. After treatment of the 24 patients with Oral Mucositis, the number decreased to 9 patients. The grades of patients’ oral mucositis also decreased to lower grades The two measures were effective but sodium bicarbonate mouthwash was more significant effective as a treatment and preventive measure for oral mucositis (p=0.044) than ice cubes (p=0.022).

scholarly journals The Effect of Perineural Injection in the Treatment of Carpal Tunnel Syndrome

QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
M A Elsebaie ◽  
N H Elarousi ◽  
E A Elattar ◽  
A A Mohamed
Keyword(s):  
Sodium Bicarbonate ◽  
Negative Correlation ◽  
Nerve Conduction ◽  
Randomized Study ◽  
Prospective Randomized Study ◽  
Statistical Significant Difference ◽  
Positive Correlation ◽  
Perineural Injection ◽  
Significant Difference ◽  
Before And After

Abstract Background This study was carried out to determine the effectiveness of perineural injection of dextrose 5 % buffered with sodium bicarbonate subcutaneously in treating patients with mild to moderate CTS. It was a prospective randomized study that performed on twenty cases with idiopathic CTS; they were diagnosed clinically and electrophysiologically according to AANEM criteria (2002). Objectives To study the effectiveness of perineural injection of dextrose 5 % buffered with sodium bicarbonate subcutaneously in treating patients with mild to moderate CTS. Patients and Methods It was a prospective randomized study that performed on twenty cases with idiopathic CTS; they were diagnosed clinically and electrophysiologically according to AANEM criteria (2002). All patients received PIT sessions. The injection done once weekly for 6 weeks. They were assessed before and after the treatment sessions by the following: provocative tests (Tinel, phalen and reverse phalen), clinical assessment scale (VAS and BCTQ"SSS, FSS") and nerve conduction study. Results By the end of the treatment, All provocative tests & All assessment scores showed a highly statistical significant difference (p > 0.01). Regarding sensory examination: night parethesia, hand pain and tingling &numbness showed a highly statistical significant difference (p > 0.01). Our results as regard nerve conduction studies of DML, sensory CV and DSL —difference between median and ulnar nerves showed that there was a statistical significant difference with improvement and there was a highly statistical significant difference with improvement as regard DSL and DML-difference between median and ulnar nerves. Before treatment VAS has a positive correlation with DML (r = 0.448, P < 0.05), another significant positive correlation was found between SSS and DSI (r = 0.45 , p < 0.05), but there was a negative correlation between VAS and the following MCV (r=-0.536, p < 0.05) and SCV (r= -0.462, p < 0.05). After treatment there was a negative correlation between VAS and the following SCV (r = -0.528, p < 0.05) and MCV (r= -0.618, p- 0,01 ). Conclusion Our study revealed that PIT Of D5W is an effective treatment for patients with mild to moderate CIS.

CP-014 Intravenous acetaminophen use before and after protocol implementation in a teaching hospital

2017 ◽  
Author(s):  
Z Jahangard Rafsanjani ◽  
A Ghorbani ◽  
E Laali ◽  
A Sarayani ◽  
S Najafi ◽  
...  
Keyword(s):  
Teaching Hospital ◽  
Protocol Implementation ◽  
Intravenous Acetaminophen ◽  
Before And After

scholarly journals Improving patient flow in acute psychiatric wards: enhanced bed management and trusted assessment

2020 ◽  
Vol 44 (4) ◽  
pp. 159-162
Author(s):  
Douglas Turkington ◽  
Steve Moorhead ◽  
Gordon D. Turkington ◽  
Carla King ◽  
Leigh Bell ◽  
...  
Keyword(s):  
Mental Health ◽  
Patient Flow ◽  
Cost Effective ◽  
Management Team ◽  
Bed Management ◽  
Cost Effective Approach ◽  
Before And After ◽  
Acute Psychiatric Wards ◽  
Two Measures ◽  
Out Of Area

Aims and methodIn three localities in a mental health trust in England, an enhanced bed management team was established to improve patient flow and reduce out-of-area placements. Trusted assessments were provided to support risk management and conflict resolution. Two measures of flow were compared before and after the team was established.ResultsThe trusted assessment recommendation was for discharge in 70% of cases. The number of out-of-area placements was significantly reduced (P < 0.05), saving £616 876 over a 12-month period. Patient flow was significantly improved in one of the three localities as measured by patients/bed/6-month period (P < 0.05). In one of the other localities increased use of trusted assessment input and reduced numbers of patients being transferred in are recommended to improve flow.Clinical implicationsMental health trusts should consider the establishment of an enhanced bed management team, including trusted assessment, as a safe and cost-effective approach to improving patient flow and reducing the need for out-of-area placement.

scholarly journals Satisfaction of patients received in emergencies in the department of obstetrics and gynecology at the Yalgado Ouedraogo teaching hospital: comparative study before and after the introduction of free care

2019 ◽  
Vol 8 (8) ◽  
pp. 3259
Author(s):  
Hyacinthe Zamané ◽  
Sibraogo Kiemtoré ◽  
Paul Dantola Kain ◽  
Lydie Zounogo Ouédraogo ◽  
Blandine Bonané Thiéba
Keyword(s):  
Health Care ◽  
Quality Of Care ◽  
Teaching Hospital ◽  
Health Care Services ◽  
Care Process ◽  
Important Indicator ◽  
Care Services ◽  
Before And After ◽  
Free Care

Background: The quality of care perceived by the users of health care services is an important indicator of the quality of care. The aim of this study was to assess the satisfaction of patients received in obstetric and gynecological emergencies department of Yalgado Ouedraogo Teaching Hospital before and after the introduction of free care.Methods: This was a cross-sectional investigation. Data collection was carried out from February to July 2016, covering the last three months before the start of free care and the first three months of implementation of this free policy in Burkina Faso.Results: A total of 620 patients formed the sample. The reception (p=0.0001), the waiting period (p=0.0001), respect for treatment schedules (p=0.0001), respect for intimacy (p=0.0001), communication between providers and patients (p=0.007), the comfort of the delivery room (p=0.003) and the comfort of the ward room (p=0.002) were more favorably appreciated by patients before the free treatment than during that period. Overall patient satisfaction was better before the effectiveness of free care (p=0.003).Conclusions: The realization of free care process was followed by a lower patient’s satisfaction reflecting an alteration in the quality of health care services. A situational analysis of this free health care process is necessary in order to make corrective measures. Also adequate preventive measures should be adopted before any implementation to a larger scale of this free policy.

scholarly journals Sodium bicarbonate and HEPES as buffer components for cooling the semen of pony stallions

2018 ◽  
Vol 39 (2) ◽  
pp. 631
Author(s):  
Janislene Mach Trentin ◽  
Luiz Augusto Machado Centeno ◽  
Taison De Souza Balestrin ◽  
Thainá Minela ◽  
Guilherme Machado Zanatta ◽  
...  
Keyword(s):  
Sodium Bicarbonate ◽  
Artificial Insemination ◽  
Membrane Integrity ◽  
Milk Powder ◽  
Skim Milk ◽  
Skim Milk Powder ◽  
Mitochondrial Activity ◽  
Sperm Viability ◽  
Progressive Motility ◽  
Before And After

The composition of semen diluents can modify its viability during cooling. The buffering effects of HEPES and sodium bicarbonate were evaluated considering the pH and sperm viability. The semen of seven adult Brazilian ponies was evaluated before and after cooling at 5oC for 24 h and 48 h. A non-buffered skim milk powder extender (C) and the same extender buffered with sodium bicarbonate (SB) and HEPES (H) were used. After dilution, semen (three ejaculates/pony) was centrifuged and the seminal plasma discarded. Sperm was then diluted with SB, H or C and its concentration adjusted to 50 x 106 sptz/mL. Progressive motility evaluated after dilution showed similar results with all extenders (71.42% (SB), 74.28% (H), and 74.52% (C)). Sperm motility was evaluated 24 h and 48 h after cooling for SB (44.76% and 25.23%), H (51.42% and 38.09%) and C (54.05% and 41.66%, respectively). Plasma membrane integrity was similar after exposure to the three extenders (62.71% (SB), 68.76% (H), and 69.23% (C)). Mitochondrial activity was higher in SB immediately after dilution (SB= 1.05nm, H= 0.81nm, C= 0.79nm), and after 24 h (0.83nm (SB), 0.73nm (H) and 0.64nm (C)). After 48 h, the mitochondrial activity decreased to 0.72nm (SB), 0.69nm (H), and 0.63nm (C) (P > 0.05). The pH, osmolarity and pH after 48 h of cooling of the diluted semen were higher in SB (8; 382; 7.9), intermediate in H (7.5; 362; 7.32) and lower in C (7.16; 350; 7.07). Lipid peroxidation and its induction were similar in all groups. Data were analyzed by analysis of variance (ANOVA), and Duncan’s test was used to evaluate the significant differences (P < 0.05). Sodium bicarbonate reduced the progressive motility and increased the semen pH. The extender C was considered more appropriate for immediate use in artificial insemination. The non-buffered and HEPES-buffered extenders were considered appropriate for the cooling of equine semen for 48 h at 5°C.

scholarly journals 154 Enhancing Communication Between Foundation Doctors and Radiologists

2021 ◽  
Vol 108 (Supplement_2) ◽  
Author(s):  
Y H Chuang ◽  
V Jones ◽  
M Trail ◽  
M Szewczyk-Bieda ◽  
G M Nandwani
Keyword(s):  
Communication Skills ◽  
Teaching Hospital ◽  
Baseline Level ◽  
Patient Management ◽  
Likert Scale ◽  
Formal Training ◽  
Radiological Imaging ◽  
Teaching Session ◽  
Post Graduate ◽  
Before And After

Abstract Introduction Facilitating radiological imaging for patients is an essential task for all Foundation Year (FY) doctors. Achieving competence in this task can expedite patient management. We evaluated the confidence and skills of FYs in facilitating radiological imaging before and after introduction of formal training. Method Surgical FYs working at a teaching hospital were surveyed to evaluate their baseline level of competence in booking and discussing imaging with radiology colleagues. Parameters were measured on a Likert scale, including confidence in discussing requests and satisfaction of their own performance following discussions. Eight radiology consultants were surveyed to evaluate their opinions on FYs’ communication and established areas for improvement. A teaching session was then delivered to improve communication skills. Furthermore, PACCSS poster was introduced to remind the FYs of the salient information required when discussing imaging. Results One month after the intervention, the participants were re-surveyed. This demonstrated a statistically significant improvement in self-reported confidence from 5.3/10 to 7.3/10 (p &lt; 0.001), and in satisfaction of own performance from 5.4/10 to 7.0/10 (p &lt; 0.001). Conclusions We identified deficiencies in surgical FY doctors’ confidence and skills in facilitating radiological imaging. There was a demonstrable benefit with focused training. Inter-specialty communication should be introduced into under- and post-graduate educational curriculum.

Topical application of hangeshashinto (TJ-14) in the management of chemotherapy-induced oral mucositis: A preliminary study.

2011 ◽  
Vol 29 (4_suppl) ◽  
pp. 603-603 ◽  
Author(s):  
T. Kono ◽  
M. Satomi ◽  
Y. Ebisawa ◽  
N. Chisato ◽  
M. Suno ◽  
...  
Keyword(s):  
Oral Mucositis ◽  
Topical Application ◽  
Tissue Injury ◽  
Tap Water ◽  
Therapeutic Effects ◽  
Traditional Medicines ◽  
Before And After ◽  
The Common ◽  
Grade 3 ◽  
Chemotherapy Patients

603 Background: Oral mucositis is a common toxicity associated with cytotoxic chemotherapy used for cancer treatment and results in severe discomfort and impairs patients' ability to eat, swallow, and talk. The treatment of chemotherapy-induced oral mucositis is not well established. The cyclooxygenase pathway mediates tissue injury and pain through upregulation of pro-inflammatory prostaglandins. Recent study showed that one of the Japanese traditional medicines (kampo), hangeshashinto (TI-14), may be useful for periodontal disease via downregulation of pro-inflammatory prostaglandins in human. The aim of this study was to evaluate the effect of TJ-14 on chemotherapy- induced oral mucositis. Methods: Fourteen patients with chemotherapy-induced oral mucositis during mFOLFOX6 or FOLFIRI treatment for requiring to the metastasis of advanced colorectal cancer were received topical application of TJ-14. Topical TJ-14 was applied to the oral mucositis three times a day. Patients were asked to make 50 mL of TJ-14 solution (2.5 g) with a tap water and were advised to rinse the TJ-14 solution on the oral mucosa for 10 seconds and then to spill it. Additionally, TJ-14 was topically applied with a cotton pellet on the oral mucositis. The above treatment was advised throughout the course of chemotherapy. Patients were evaluated for the oral mucositis using the Common Terminology Criteria for Adverse Events (CTCAE) version 4 before and after 2-weeks TJ-14 treatment. Results: Thirteen of the fourteen patients (92.8 %) responded to the TJ-14 therapy. There was significant reduction in the grade 3/4 mucositis from 3.2 to 1.8 (p=0.02) as well as in the grade 1/2 mucositis from 1.6 to 0.6 (p=0.034). There is no patient showed worse than before. The compliance of TJ-14-treatment was good. Conclusions: Topical application of TJ-14 may have therapeutic effects on chemotherapy-induced oral mucositis via downregulation of pro-inflammatory prostaglandins. No significant financial relationships to disclose.

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