A Retrospective Study on the Delivery Outcome among the Term Pregnant Women

Background There are a lack of studies about factors influencing congenital syphilis (CS) in economically underdeveloped areas, such as Jiangxi Province, China. Methods A retrospective study was conducted based on the information system of prevention of mother-to-child transmission of syphilis management in Jiangxi Province, China. Pregnant women with syphilis infection who delivered ≥28 gestational weeks and registered in this system from 1 January 2013 to 2030 June 2018 were enrolled. Maternal characteristics and treatment regimens associated with CS were evaluated using multivariable regression analysis. Results 1196 syphilis infected mothers and their 1207 infants were included in the analyses, and 116 infants were diagnosed with CS, providing an overall incidence of 9.61% (116/1207). Multivariable logistic regression analysis showed that increasing maternal age was barely associated with the risk of CS (adjusted odds ratio (aOR) = 0.97, 95% CI, 0.93–1.00, p = .047). Women with a high nontreponemal serum test titer (≥1:8) had a 126% increased risk of delivering an infant with CS than those with a low titer (<1:8) (aOR = 2.26, 95% CI, 1.51–3.39, p < .001). The risk for CS decreased significantly in infants born to mothers receiving adequate treatment than those receiving no treatment (aOR = 0.36, 95% CI, 0.21–0.61, p < .001). Conclusions Adequate treatment is critical for the prevention of CS. Further strategies focusing on early diagnosis and adequate treatment among syphilis infected pregnant women, particularly among those with younger age and high nontreponemal titer, should be strengthened to prevent CS.

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Peculiarities of pregnansy and childbirth in patients with a burdened gynecological anamnesis

Reproductive health of woman ◽

10.30841/2708-8731.5.2021.224480 ◽

2020 ◽

Vol 5 ◽

pp. 5-10

Author(s):

T. P. Andriichuk ◽

A. Ya. Senchuk ◽

V. I. Chermak

Keyword(s):

Retrospective Study ◽

High Risk ◽

Pregnant Women ◽

Postpartum Period ◽

Control Group ◽

Careful Monitoring ◽

Pregnancy And Childbirth ◽

History Of ◽

High Level ◽

Adaptive Reactions

The objective: to study the features of pregnancy, childbirth, postpartum period, fetal status and newborns in patients with a history of chronic salpingo-оophoritis.Materials and methods. Conducted a retrospective study of 150 birth histories and neonatal development maps. All patients were divided into two groups. The main group includes 100 patients with chronic salpingo-оophoritis, for which they received anti-inflammatory treatment from 1 to 3 times before pregnancy. The control group included 50 pregnant women who did not suffer from chronic salpingo-оophoritis.Results. Our analysis of pregnancy, childbirth, fetal and neonatal status in women with chronic salpingo-оophoritis indicates that such patients have a complicated obstetric and gynecological and somatic history, which forms an unfavorable basic condition of organs and systems, imperfect adaptation to pregnancy, high risk of failure of adaptive reactions. The result is a violation of the formation and development of the mother-placenta-fetus system and, as a consequence, a high level of complications during pregnancy, childbirth and perinatal pathology.Conclusion. Patients suffering from chronic salpingo-oophoritis should be considered at high risk of possible complications during pregnancy and childbirth. This category of women needs quality preconception training and careful monitoring during pregnancy.

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The impact of levothyroxine exposure on delivery outcome in hypothyroid pregnant women (PETAL study): A five-year retrospective cohort study

Obstetric Medicine ◽

10.1177/1753495x211064108 ◽

2021 ◽

pp. 1753495X2110641

Author(s):

Diana Oprea ◽

Nadine Sauvé ◽

Jean-Charles Pasquier

Keyword(s):

Cohort Study ◽

Pregnant Women ◽

Retrospective Cohort Study ◽

Retrospective Cohort ◽

Caesarean Delivery ◽

Significant Risk ◽

Significant Risk Factor ◽

Singleton Pregnancy ◽

Delivery Outcome ◽

The Impact

Background Hypothyroidism affects 3% of pregnant women, and to date, no studies have addressed the impact levothyroxine-treated hypothyroidism on delivery outcome. Methods This retrospective cohort study was conducted among 750 women with a singleton pregnancy who gave birth between 2015 and 2019. Delivery modes were compared between 250 hypothyroid women exposed to levothyroxine and 500 euthyroid control women. The aim of this study was to determine the impact of levothyroxine exposure on delivery outcome. Results Multiple logistic regression showed no significant association between exposure to levothyroxine and the overall rate of caesarean delivery (aOR 1.1; 95% CI 0.8 to 1.6). Mean TSH concentrations were significantly higher throughout the pregnancy in hypothyroid women despite levothyroxine treatment. Maternal and neonatal outcomes in both groups were not different. Conclusion Hypothyroidism treated with levothyroxine during pregnancy according to local guidelines is not a significant risk factor for caesarean delivery.

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FOLATE METABOLISM IMPAIRMENT IN SMOKING PREGNANT WOMEN

Journal of obstetrics and women s diseases ◽

10.17816/jowd62234-42 ◽

2013 ◽

Vol 62 (2) ◽

pp. 34-42

Author(s):

Tatyana Valeryevna Semenova ◽

Yuliya Pavlovna Milyutina ◽

Aleksandr Vartanovich Arutyunyan ◽

Olga Nikolayevna Arzhanova

Keyword(s):

Plasma Level ◽

Pregnant Women ◽

Homocysteine Level ◽

Late Pregnancy ◽

Folate Metabolism ◽

Premature Delivery ◽

Essential Condition ◽

Delivery Outcome ◽

Pregnancy And Delivery ◽

High Smoking Rate

Tobacco smoking is one of the pressing issues of public health. Russia ranks among the countries with a very high smoking rate. Smoking frequency among pregnant women in St. Petersburg is about 26.4%, among which 18.9% of the women smoke every day, and the rest 7.5% of them on the occasion. Complications from pregnancy (threatening miscarriage, premature delivery, anaemia) and from labour and delivery (labour abnormalities) in the smoking women occurs at almost twice the rate in those non-smoking, threatening miscarriage and anaemia notably having a more severe clinical picture and being more reluctant to the therapy. Smoking is one of the risk factors of hyperhomocysteinemia, which is in turn a marker of the folate metabolism impairment in the organism. It has been shown that homocysteine plasma level increases in the smoking pregnant women. Besides, a significant decrease in folate plasma level has been found in the same women. It is a folate deficiency that most of all raises homocysteine level in blood plasma. It has been proved that elevated homocysteine level has a direct toxic effect on the endothelium. Microthrombosis and microcirculation loss result in a series of obstetric complications. In late pregnancy, hyperhomocysteinemia causes chronic fetoplacental insufficiency and chronic intrauterine hypoxia. Therefore, many complications from pregnancy, such as gestosis and fetoplacental insufficiency, are associated with hyperhomocysteinemia, which is most probably caused by the smoking derived folate metabolism impairment. Supplementary folate and vitamin B complex therapy may possibly improve the pregnancy and delivery outcome in the pregnant women with high homocysteine plasma level. This, however, requires supportive clinical trials. Smoking cessation at birth spacing and prevention of hyperhomocysteinemia must be an essential condition for favourable prognosis for pregnancy.

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Obstetric outcomes of women referred for delivery to a tertiary hospital in northern Tanzania– a descriptive retrospective study based on a hospital birth registry

10.21203/rs.2.24072/v1 ◽

2020 ◽

Author(s):

Carolyn Lissu ◽

Helena Volgsten ◽

Festu Mazuguni ◽

Eusebious Maro

Keyword(s):

Retrospective Study ◽

Pregnant Women ◽

Tertiary Hospital ◽

Health Facilities ◽

Obstetric Outcomes ◽

Birth Registry ◽

Maternal Deaths ◽

Hospital Birth ◽

Northern Tanzania ◽

Lower Health

Abstract Background: Maternal mortality remains a great challenge in a low-income country like Tanzania, despite global and national efforts to improve women’s reproductive health. Timeliness and appropriateness of referral from a lower- to higher-level health facility comprise an important factor for the obstetrics outcome for pregnant women. This study aimed to determine the obstetric outcomes, such as maternal deaths, of women referred to KCMC, a tertiary hospital in northern Tanzania. Methods: A descriptive retrospective study based on a hospital birth registry was conducted, using consecutive stored data on pregnant women referred while in labor and managed at the KCMC tertiary hospital in northern Tanzania between the years 2000 and 2015. All referred pregnant women whose labor status information was missing during admission were excluded from the study. Results: During the study period, a total of 53662 deliveries were managed at KCMC. Among these, 6066 women were referred from lower health facilities, with 4193 (69.2%) of them being referred while in labor. The main reason for referral was poor progress of labor (31.0%), followed by prolonged labor (27.1%) and obstructed labor (19.5%). For 1859 (44.6%) women, delivery was by caesarean section. A total of 292 maternal deaths occurred between 2000 and 2015. Of these, almost a quarter (22.6%) occurred in women referred from other health facilities while in labor. Conclusions: Most of the maternal complications during labor and delivery were prevalent among women referred from lower health facilities. This underscores the need to strengthen lower health facilities’ ability to detect complications in timely manner and provide effective emergency obstetric care, as well as to refer women to higher-level facility.

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Incidence of Urinary Tract Infection among Pregnant Women Attending Antenatal Clinic at Federal Medical Centre, Bida, Niger-State, North Central Nigeria: A Retrospective Study

Challenges in Disease and Health Research Vol. 7 ◽

10.9734/bpi/cdhr/v7/1587c ◽

2021 ◽

pp. 65-74

Author(s):

O. A. Akobi ◽

E. G. Emumwen ◽

P. O. Uyigue ◽

E. C. Akobi ◽

S. O. Akinola ◽

...

Keyword(s):

Urinary Tract Infection ◽

Retrospective Study ◽

Urinary Tract ◽

Tract Infection ◽

Pregnant Women ◽

Antenatal Clinic ◽

Medical Centre ◽

North Central

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RUPTURE OF AMNIOTIC MEMBRANES IN PRETERM, AS A FACTOR IN THE DEVELOPMENT OF OBSTETRICS COMPLICATIONS

Doctor's Herald/ Доктор ахборотномаси /Вестник врача ◽

10.38095/2181-466x-2020931-76-79 ◽

2020 ◽

Vol 93 (1) ◽

pp. 76-79

Author(s):

Iroda Tosheva ◽

◽

N. Ashurova ◽

Gulchekhra Ikhtiyarova

Keyword(s):

Retrospective Study ◽

Pregnant Women ◽

Significant Role ◽

Perinatal Complications ◽

Premature Rupture ◽

Perinatal Center ◽

History Of ◽

Amniotic Membranes

This article presents the results of the retrospective study of the childbirth history of 106 pregnant women in whom labor was complicated by premature rupture of the membranes, delivery in the Bukhara regional perinatal center for the period 2017-2019 years. The results show the significant role of premature rupture of the membranes in the development of obstetrics and perinatal complications, especially in women with a history of somatic and gynecological anamnesis

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Clinical analysis of ten pregnant women with COVID-19 in Wuhan, China: A retrospective study

International Journal of Infectious Diseases ◽

10.1016/j.ijid.2020.04.047 ◽

2020 ◽

Vol 95 ◽

pp. 294-300 ◽

Cited By ~ 25

Author(s):

Dongmei Cao ◽

Heng Yin ◽

Jun Chen ◽

Fei Tang ◽

Min Peng ◽

...

Keyword(s):

Retrospective Study ◽

Pregnant Women ◽

Clinical Analysis

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The Effect of Nicoumalone on Embryogenesis: A Retrospective Study

Indian Journal of Cardiovascular Disease in Women WINCARS ◽

10.1055/s-0038-1677057 ◽

2018 ◽

Vol 03 (02/03) ◽

pp. 189-192

Author(s):

Chaitanya Nelavayi ◽

Kumar Achukatla ◽

Bhanu Badhvel ◽

Sree Gurram ◽

Vanajakshamma Velam ◽

...

Keyword(s):

Retrospective Study ◽

Pregnant Women ◽

Valve Replacement ◽

Heart Valve ◽

Mechanical Heart Valve ◽

Medical Sciences ◽

Live Births ◽

Replacement Surgery ◽

Valve Prostheses ◽

Valve Replacement Surgery

Abstract Objective To study the effect of nicoumalone on embryogenesis in women who have undergone mechanical heart valve replacement surgery. Design It is a retrospective study done at Sri Venkateswara Institute of Medical Sciences (SVIMS), Tirupati. Results Total 28 pregnancies were reported in 12 women with mechanical heart valve prostheses. Of these, 19 were live births, 9 abortions, and no stillbirths and miscarriages were noted in pregnant women. There were 11 hemorrhagic, 3 neurologic, 2 thromboembolic, and 1 stuck valve complications observed in mothers; and 2 low birth weights, 2 pneumonia, and 1 jaundice observed in the child. Conclusion There were no abnormalities observed in children whose mothers were taking nicoumalone throughout pregnancy based on echo results and clinical examination.

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