scholarly journals Urinary schistosomiasis and iron deficiency anemia among Malian school children

2009 ◽  
Vol 9 (30) ◽  
pp. 1845-1858
Author(s):  
Mohamed Ayoya ◽  
◽  
KM Koné ◽  
AK Traoré ◽  

Anemia continues to be a major public health problem in many countries. The prevalence and intensity of urinary schistosomiasis, which contributes to anemia, often peak at school age adding to that age group’s nutrition and disease burdens. However, unlike malaria and hookworm infections, little is known on the role of urinary schistosomiasis in iron deficiency anemia. The objective of this study was to assess the prevalence of iron deficiency anemia and the effect of iron supplementation on hemoglobin (Hb) and serum ferritin (SF) levels among school children infected with Schistosoma haematobium in Bamako, the capital city of Mali. A total of 150 anemic school children between 7 and 12 years were randomly assigned to receive either 40mg/kg of praziquantel or 40mg/kg of praziquantel (P) + daily 66 mg of iron (Fe), five days a week for three months. Hb and SF were measured at baseline and at 6 and 12 weeks of the intervention. Only children who had complete Hb and SF data at each stage of the trial were included in the statistical analyses (n = 74 in the P+Fe group; n = 66 in the P group). At baseline, mean Hb (g/dl) was 10.53±0.93 in the P group and 10.47±1.17 in the Fe+P group; mean SF (µg/l) was 34.39±37.58 in the P group and 29.82±23.34 in the Fe+P group, and the prevalence of iron deficiency was 17.2%. At 6 and 12 weeks of the intervention, there was an important reduction in anemia and in iron deficiency in both treatment groups. Mean Hb (g/dl) was higher in the Fe+P group (11.63±0.88 and 11.55±0.94) than in the P group (11.14±0.98 and 10.84±0.86) at 6 and 12 weeks, respectively. Mean SF (µg/l) was also higher in the P+Fe group (74.26±40 and 100.29±53.92) than in the P group(40.65±35.63 and 40.70±29.57) at 6 and 12 weeks, respectively. In these Schistosoma haematobium infected children, iron deficiency was prevalent and treatments with P alone or in combination with Fe supplementation were able to increase hemoglobin and iron stores. Neither P nor P+Fe by alone completely reversed anemia in this sample population.

Nutrients ◽  
2022 ◽  
Vol 14 (2) ◽  
pp. 277
Author(s):  
Ali Sungkar ◽  
Saptawati Bardosono ◽  
Rima Irwinda ◽  
Nurul R. M. Manikam ◽  
Rini Sekartini ◽  
...  

Iron deficiency anemia (IDA) has a long-term impact on each life stage and remains worldwide a major public health problem. Eleven experts were invited to participate in a virtual meeting to discuss the present situation and the available intervention to prevent iron deficiency anemia in Indonesia. The experts consisted of obstetric gynecologists, pediatricians, nutritionists, midwives, a clinical psychologist, and an education expert. Existing interventions focus attention on preconception and early childhood stages. Considering the inter-generational effects of IDA, we call attention to expanding strategies to all life stages through integrating political, educational, and nutritional interventions. The experts agreed that health education and nutritional intervention should be started since adolescence. Further research to explore the effectiveness of these interventions would be important for many regions in the world. The outcome of this Indonesian consensus is applicable worldwide.


Anemia ◽  
2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Abdullah Ahmed Al-alimi ◽  
Salem Bashanfer ◽  
Mohammed Abdo Morish

Background. Iron deficiency anemia (IDA) is one of the most common types of nutritional anemia in the worldwide and considered a major public health problem in developing countries especially in Yemen. Therefore, this cross-sectional study was conducted to determine the prevalence and risk factors of IDA among apparently healthy Yemeni students at Hodeida University. Method. Five hundred blood samples (326 males and 174 females) were collected randomly from medical students at Hodeida University. Participants were subjected to different tests including complete blood counts (CBC), serum ferritin (SF), serum iron (SI), and total iron binding capacity (TIBC). Moreover, a questionnaire was designed to collect demographics, food and drink habits, and socioeconomic status. Result. The overall prevalence of IDA was 30.4%  (n=152), of whom 54.00% were females (n=82) and 46.0% were males (n=70). Students aged 20–22 years were found more anemic with prevalence 59.2% than students aged 17–19 years (25.0%) and 23–25 years (15.8%). Statistical analysis showed regularly having breakfast had significant (p < 0.001) role in preventing development of IDA compared with irregularly having breakfast. Infrequent consumption of vegetables/fruits; meat, fish, chicken; tea drinking; low household income; smoking and khat (Catha edulis) chewing showed a significant role (p < 0.001) in provoking of IDA, whereas consumption of coffee and cola showed insignificant influence (p=0.585; p=0.513) on IDA. Conclusion. This study revealed that the majority of university students, especially females, have IDA that might become worse by malnutrition, lifestyle habits, and lack of awareness. Our results suggest that IDA can be prevented by providing proper knowledge on the healthful diet, improved lifestyle, and harmful effect of IDA to the students.


QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Karam M Bayoumy ◽  
Nermeen A. M Elghareeb ◽  
Samar G Ragab

Abstract Background Iron deficiency anemia (IDA) is a major public health problem in Egypt, especially among pregnant women. The most commonly used treatment is oral administration of iron as ferrous sulfate which often fails to exert significant effects with many adverse effects. Lactoferrin is a glycoprotein which belongs to proteins capable of binding and transferring iron. This study was done to evaluate the effectiveness, safety and acceptability of lactoferrin in comparison to ferrous sulfate. Methods This randomized clinical trial was conducted in outpatient clinic under supervision of department of Obstetrics and Gynecology, Faculty of medicine, Ain Shams University, Cairo, Egypt from August 2019 to February 2020. 140 women with iron deficiency anemia in second trimester were recruited and randomly assigned to either group. First group received lactoferrin 200 mg sachets once daily and second group received 100 mg of dried ferrous sulfate capsules twice daily for 4 consecutive weeks. Hemoglobin, hematocrit levels, mean corpuscular volume, and serum ferritin were assessed before and after therapy. Results The increase in haemoglobin was significantly higher in lactoferrin group. Number of cases achieved Hb level ≥10.5 was significantly more frequent in lactoferrin group. Compliance was significantly more frequent in lactoferrin group than in ferrous sulfate group. Maternal side effects were significantly less frequent in lactoferrin group than in ferrous sulfate group. Conclusion Oral lactoferrin is well tolerated and effective as compared to traditional treatment by ferrous sulfate.


2021 ◽  
Vol 01 (01) ◽  
pp. 24-28
Author(s):  
Laxmi Shukla ◽  
◽  
Dimpal Singh ◽  
Ranjeet Kumar ◽  
Sabiya Khatoon ◽  
...  

Background of the study: Anemia continues to be a major public health problem in developing countries including India. It is the most common cause of malnutrition in the world and is the eighth leading cause of diseases in girls and women in developing counties. About one third of the global population is anemic (WHO 2010) [1]. Knowledge regarding the causes, prevention and management of iron deficiency among reproductive age women plays an important role in reducing the mortality and morbidity rates. The aim of this study is to assess the knowledge regarding iron deficiency anemia among reproductive age group women. Methodology: By using descriptive survey design, 50 women who met the criteria were selected by purposive sampling technique. Structured questionnaire was used to gather the data Data were analyzed by descriptive and inferential statistics. Results: Findings shows that 6% of reproductive age group women had inadequate level of knowledge regarding anemia, 72% had moderate level of knowledge and 22% of them had adequate level of knowledge. Conclusion: Overall findings of this study revealed that knowledge on iron deficiency anemia was inadequate among reproductive age group women. There is a need to improve the health care services, facilities and more importantly knowledge among the women on topics related to anemia and its prevention.


Author(s):  
L. S. Amarnath ◽  
Loushambam Samananda Singh ◽  
Ksh. Gomti Devi ◽  
R. K. Ranjit

Background: Iron deficiency anemia (IDA), one of the most common types of nutritional anemia worldwide is considered a major public health problem in developing countries. Prevalence in India remains alarmingly high. Population of Manipur, a small state in the north-eastern part of India, is different with distinct race, culture, socio-demographic pattern and dietary habits. Therefore, this cross-sectional study was conducted to determine the prevalence and risk factors of IDA among apparently healthy school children of Manipur, India. Methods: Three hundred and seventy-nine blood samples (163 males and 216 females) were collected randomly from urban and rural school children in the age group of 13 to 19 years from Imphal west and Thoubal districts of Manipur respectively. Eligible participants were subjected to haemoglobin (Hb) estimation and serum ferritin (SF) assay. Moreover, a questionnaire was designed to collect demographics, food and drink habits, hygienic practices and socioeconomic status. BMI of the students were also recorded. Results: The overall prevalence of IDA was 23.2% (n = 88), of whom 81.81% were females (n = 72) and 18.18% were males (n = 16). Prevalence of IDA among the males and females was higher in the rural compared to urban schools but not statistically significant. Correlation between BMI and Hb was significant (p < 0.05) but not with serum ferritin status. Students belonging to the middle income group had the highest prevalence of ferritin deficiency followed by the high income group and low income group respectively. Both the Hb and serum ferritin levels of students who do hand wash before meals were significantly higher than those who do not. Both hemoglobin and serum ferritin levels do not differ significantly among students who prefer home-made traditional food and junk food. Conclusion: This study revealed that the majority of the students, especially females, have IDA that might become worse by malnutrition, lifestyle habits, and lack of awareness. Our results suggest that IDA can be prevented by providing proper knowledge on the healthful diet, improved lifestyle, and harmful effect of IDA to the students.


Foods ◽  
2020 ◽  
Vol 9 (12) ◽  
pp. 1871
Author(s):  
Ângela Liberal ◽  
José Pinela ◽  
Ana Maria Vívar-Quintana ◽  
Isabel C. F. R. Ferreira ◽  
Lillian Barros

Iron deficiency remains one of the main nutritional disorders worldwide and low iron intake and/or bioavailability are currently the major causes of anemia. To fight this public health problem, the scientific challenge is to find an iron form with sufficient bioavailability to increase its levels in humans through food fortification. In turn, biofortification appears as a comparatively advantageous and bearable strategy for the delivery of vitamins and other micronutrients for people without access to a healthy and diverse diet. This approach relies on plant breeding, transgenic techniques, or agronomic practices to obtain a final food product with a higher iron content. It is also known that certain food constituents are able to favor or inhibit iron absorption. The management of these compounds can thus successfully improve the absorption of dietary iron and, ultimately, contribute to fight this disorder present all over the world. This review describes the main causes/manifestations of iron-deficiency anemia, forms of disease prevention and treatment, and the importance of a balanced and preventive diet. A special focus was given to innovative food fortification and biofortification procedures used to improve the iron content in staple food crops.


2009 ◽  
Vol 8 (3) ◽  
pp. 259-263 ◽  
Author(s):  
Muhammad Ramzan ◽  
Irshad Ali ◽  
Abdus Salam

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