DIETARY PATTERNS AND CARDIOVASCULAR HEALTH OF THE POPULATION (ESSE-RF) STUDY IN THE KEMEROVO REGION

Nutrition is the one of the most important factors of the formation of a state of health of the person that requires the solution of two main objectives: determination of main population tendencies in the dietary patterns (DP) and the study of the influence of consumption of certain feedstuffs, products and groups of products on a state of health of the person. Within multicenter epidemiological research of the ESSE-RF the analysis of DP of the population of the Kemerovo region (1628 people aged of 25-64 years) and their association with indices of cardiovascular health is carried out. For grouping (determination of DP) frequencies of consumption of 13 groups of foodstuff the factorial analysis were used (a method of main components). The characteristic of commitment to the allocated DP in various age, gender and social-economic groups of the population, and also association of commitment to DP with factors of cardiovascular risk and some cardiovascular diseases is given. There were selected four DP types explaining of 44.8% of the structure of the frequency of consumption of foodstuff. In three out of four DPs there were revealed associations with the age and gender structure and education level of the population. According to two DPs multiple associations with indices of the cardiovascular health were noted: systolic and diastolic blood pressure, the waist circumference, the level of cholesterol, triglycerides, glucose, presence of arterial hypertension, obesity, hypertriglyceridemia. The obtained associations allow to characterize “dairy” DP (high frequency of consumption of milk, sour cream, cottage cheese and cheese) as favorable, and “meat” DP (high frequency of consumption of meat, fish and seafood, birds) as adverse in respect of cardiovascular health that correspond to results of other investigations. The performed analysis has allowed characterize food preferences of the population of the Siberian region as in general on population, and on age, gender and social-economic groups. The obtained associations of two out of four DP with indices of cardiovascular health correspond to results of other Russian and foreign investigations.

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Energy Poverty: Energy Equity in a World of High Demand and Low Supply

10.1093/oxfordhb/9780190633851.013.18 ◽

2018 ◽

Author(s):

Karl-Michael Brunner ◽

Sylvia Mandl ◽

Harriet Thomson

Keyword(s):

Social Economic ◽

Energy System ◽

Developed Countries ◽

Rural Electrification ◽

The European Union ◽

Energy Poverty ◽

And Gender ◽

The One ◽

Sustainable Energy System ◽

Different Characteristics

The chapter provides insights into the different characteristics and manifestations of energy poverty—a condition that prevents the achievement of socially and materially necessary levels of domestic energy services. On the one hand, the discourse on energy poverty in developed countries (known as “fuel poverty”) is discussed (especially in the European Union), focusing on different forms of definitions and measurement, coping strategies, and attempts to combat the problem. On the other hand, the discourse on energy poverty in developing countries is outlined, highlighting especially rural electrification processes and gender relations. It is shown that energy poverty is deeply embedded in wider social, economic, political, and cultural structures, reflecting inequalities both within and across nations. Therefore, the chapter concludes that measures and interventions to tackle energy poverty must take into account wider societal structures and power relations in order to achieve a just and sustainable energy system and society.

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Detection of Circulating Tissue Factor and Factor VII in a Normal Population

Thrombosis and Haemostasis ◽

10.1055/s-0038-1650365 ◽

1996 ◽

Vol 75 (05) ◽

pp. 772-777 ◽

Cited By ~ 30

Author(s):

Sybille Albrecht ◽

Matthias Kotzsch ◽

Gabriele Siegert ◽

Thomas Luther ◽

Heinz Großmann ◽

...

Keyword(s):

Tissue Factor ◽

Normal Population ◽

Mean Value ◽

Factor Vii ◽

Significant Difference ◽

Age Dependent ◽

The Mean ◽

Highly Correlated ◽

And Gender

SummaryThe plasma tissue factor (TF) concentration was correlated to factor VII concentration (FVIIag) and factor VII activity (FVIIc) in 498 healthy volunteers ranging in age from 17 to 64 years. Immunoassays using monoclonal antibodies (mAbs) were developed for the determination of TF and FVIIag in plasma. The mAbs and the test systems were characterized. The mean value of the TF concentration was 172 ± 135 pg/ml. TF showed no age- and gender-related differences. For the total population, FVIIc, determined by a clotting test, was 110 ± 15% and the factor VIlag was 0.77 ± 0.19 μg/ml. FVII activity was significantly increased with age, whereas the concentration demonstrated no correlation to age in this population. FVII concentration is highly correlated with the activity as measured by clotting assay using rabbit thromboplastin. The ratio between FVIIc and FVIIag was not age-dependent, but demonstrated a significant difference between men and women. Between TF and FVII we could not detect a correlation.

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Two-Stage Procedure for the Quantitative Determination of Autoprothrombin III Concentration and Some Applications

Thrombosis and Haemostasis ◽

10.1055/s-0038-1655029 ◽

1967 ◽

Vol 18 (01/02) ◽

pp. 198-210 ◽

Cited By ~ 5

Author(s):

Ronald S Reno ◽

Walter H Seegers

Keyword(s):

Prothrombin Time ◽

Factor Vii ◽

Two Stage ◽

Pronounced Increase ◽

One Stage ◽

Assay Procedure ◽

Bovine Plasma ◽

The One ◽

Autoprothrombin C

SummaryA two-stage assay procedure was developed for the determination of the autoprothrombin C titre which can be developed from prothrombin or autoprothrombin III containing solutions. The proenzyme is activated by Russell’s viper venom and the autoprothrombin C activity that appears is measured by its ability to shorten the partial thromboplastin time of bovine plasma.Using the assay, the autoprothrombin C titre was determined in the plasma of several species, as well as the percentage of it remaining in the serum from blood clotted in glass test tubes. Much autoprothrombin III remains in human serum. With sufficient thromboplastin it was completely utilized. Plasma from selected patients with coagulation disorders was assayed and only Stuart plasma was abnormal. In so-called factor VII, IX, and P.T.A. deficiency the autoprothrombin C titre and thrombin titre that could be developed was normal. In one case (prethrombin irregularity) practically no thrombin titre developed but the amount of autoprothrombin C which generated was in the normal range.Dogs were treated with Dicumarol and the autoprothrombin C titre that could be developed from their plasmas decreased until only traces could be detected. This coincided with a lowering of the thrombin titre that could be developed and a prolongation of the one-stage prothrombin time. While the Dicumarol was acting, the dogs were given an infusion of purified bovine prothrombin and the levels of autoprothrombin C, thrombin and one-stage prothrombin time were followed for several hours. The tests became normal immediately after the infusion and then went back to preinfusion levels over a period of 24 hrs.In other dogs the effect of Dicumarol was reversed by giving vitamin K1 intravenously. The effect of the vitamin was noticed as early as 20 min after administration.In response to vitamin K the most pronounced increase was with that portion of the prothrombin molecule which yields thrombin. The proportion of that protein with respect to the precursor of autoprothrombin C increased during the first hour and then started to go down and after 3 hrs was equal to the proportion normally found in plasma.

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SIMPLIFIED DEXAMETHASONE SUPPRESSION TEST

Acta Endocrinologica ◽

10.1530/acta.0.0610219 ◽

1969 ◽

Vol 61 (2) ◽

pp. 219-231 ◽

Cited By ~ 14

Author(s):

V. H. Asfeldt

Keyword(s):

Cushing’S Syndrome ◽

Normal Subjects ◽

Cushing's Syndrome ◽

Dexamethasone Suppression Test ◽

Clinical Value ◽

Suppression Test ◽

The One ◽

Steroid Excretion ◽

Dexamethasone Suppression

ABSTRACT This is an investigation of the practical clinical value of the one mg dexamethasone suppression test of Nugent et al. (1963). The results, evaluated from the decrease in fluorimetrically determined plasma corticosteroids in normal subjects, as well as in cases of exogenous obesity, hirsutism and in Cushing's syndrome, confirm the findings reported in previous studies. Plasma corticosteroid reduction after one mg of dexamethasone in cases of stable diabetes was not significantly different from that observed in control subjects, but in one third of the insulin-treated diabetics only a partial response was observed, indicating a slight hypercorticism in these patients. An insufficient decrease in plasma corticosteroids was observed in certain other conditions (anorexia nervosa, pituitary adenoma, patients receiving contraceptive or anticonvulsive treatment) with no hypercorticism. The physiological significance of these findings is discussed. It is concluded that the test, together with a determination of the basal urinary 17-ketogenic steroid excretion, is suitable as the first diagnostic test in patients in whom Cushing's syndrome is suspected. In cases of insufficient suppression of plasma corticosteroids, further studies, including the suppression test of Liddle (1960), must be carried out.

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Internet usage patterns and gender differences: a decision tree approach

10.31124/advance.8040185 ◽

2019 ◽

Author(s):

Dijana Kovacevic ◽

Ljiljana Kascelan

Keyword(s):

Decision Tree ◽

Internet Usage ◽

The Internet ◽

Modified Model ◽

Explanatory Variables ◽

Internet Users ◽

Usage Patterns ◽

And Gender ◽

The One ◽

Web Developers

the present study deals with a more detailed, and updated, modified model that allows for the identification of internet usage patterns by gender. The model was modified due to the development of the internet and new access models, on the one hand, and to the fact that previous studies mainly focuses on various individual (non-interactive) influences of certain factors, on the other. The Decision Tree (DT) method, which is used in our study, does not require a pre-defined underlying relationship. In addition, the method allows a great many explanatory variables to be processed and the most important variables are easy to identify. Obtained results can serve as to web developers and designers, since by indicating the differences between male and female internet users in terms of their behaviour on the internet it can help in deciding when, where and how to address and appeal to which section of the user base. It is especially important to know their online preferences in order to enable the adequate and targeted placement of information, actions or products and services for the intended target groups.

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High-frequency dielectric heating installations. Test methods for the determination of power output

10.3403/01087681 ◽

1997 ◽

Keyword(s):

Power Output ◽

High Frequency ◽

Test Methods ◽

Dielectric Heating

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Acoustics. Determination of high-frequency sound power levels emitted by machinery and equipment

10.3403/30264709u ◽

2015 ◽

Keyword(s):

High Frequency ◽

Sound Power ◽

High Frequency Sound ◽

Frequency Sound

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Acoustics. Determination of high-frequency sound power levels emitted by machinery and equipment

10.3403/30264709 ◽

2015 ◽

Keyword(s):

High Frequency ◽

Sound Power ◽

High Frequency Sound ◽

Frequency Sound

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A Validated 2D-LC-UV Method for Simultaneous Determination of Imatinib and N-demethylimatinib in Plasma and Its Clinical Application for Therapeutic Drug Monitoring with GIST Patients

Current Pharmaceutical Analysis ◽

10.2174/1573412917999201124143834 ◽

2020 ◽

Vol 17 ◽

Author(s):

Houli Li ◽

Di Zhang ◽

Xiaoliang Cheng ◽

Qiaowei Zheng ◽

Kai Cheng ◽

...

Keyword(s):

Therapeutic Drug Monitoring ◽

One Dimension ◽

Therapeutic Drug ◽

Plasma Samples ◽

Column Temperature ◽

Injection Volume ◽

Target Analytes ◽

The One ◽

Middle Column

Background: The trough concentration (Cmin) of Imatinib (IM) is closely related to the treatment outcomes and adverse reactions of patients with gastrointestinal stromal tumors (GIST). However, the drug plasma level has great interand intra-individual variability, and therapeutic drug monitoring (TDM) is highly recommended. Objective: To develop a novel, simple, and economical two-dimensional liquid chromatography method with ultraviolet detector (2D-LC-UV) for simultaneous determination of IM and its major active metabolite, N-demethyl imatinib (NDIM) in human plasma, and then apply the method for TDM of the drug. Method: Sample was processed by simple protein precipitation. Two target analytes were separated on the one-dimension column, captured on the middle column, and then transferred to the two-dimension column for further analysis. The detection was performed at 264 nm. The column temperature was maintained at 40˚C and the injection volume was 500 μL. Totally 32 plasma samples were obtained from patients with GIST who were receiving IM. Method: Sample was processed by simple protein precipitation. Two target analytes were separated on the one-dimension column, captured on the middle column, and then transferred to the two-dimension column for further analysis. The detection was performed at 264 nm. The column temperature was maintained at 40˚C and the injection volume was 500 μL. Totally 32 plasma samples were obtained from patients with GIST who were receiving IM. Conclusion: The novel 2D-LC-UV method is simple, stable, highly automated and independent of specialized technicians, which greatly increases the real-time capability of routine TDM for IM in hospital.

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African Sustainability Advocacy Against Extractivism

INTERdisciplina ◽

10.22201/ceiich.24485705e.2015.7.52408 ◽

2015 ◽

Vol 3 (7) ◽

Author(s):

Patrick Bond

Keyword(s):

Social Reproduction ◽

Fossil Fuels ◽

Social Economic ◽

Social Activism ◽

Ecological Factors ◽

Energy Economics ◽

Extractive Industries ◽

The One ◽

Political Economic ◽

Critical Challenge

Abstract | The challenge of interdisciplinary intellectual and strategic work in the extractive industries is particularly acute at the interface of research and social activism. Numerous social movements which are dedicated to sustainability fail to ‘connect the dots’ between their campaigns and broader political-economic and political-ecological visions. This is becoming a critical challenge in Africa, where the extreme damage done by mining and fossil fuels has generated impressive resistance.However, the one obvious place to link these critiques from African activists was the Alternative Mining Indaba in Cape Town in February 2015, and a survey of narratives at that event leads to pessimism about interdisciplinary politics. The potential for much greater impact and deeper critiques of unsustainable extractivism lies in greater attention to combining social reproduction and production (as do eco-feminists), and to tackling social, economic, political and ecological factors with a more explicit structuralist critique and practical toolkit. Areas such as energy, economics and climate are ripe for linkages. One reason for optimism is a climate justice declaration made by leading civil society activists in Maputo in April 2015.

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