scholarly journals BINARY METHOD OF THE EPIDEMIOLOGICAL ANALYSIS OF INFECTIOUS INCIDENCE

2018 ◽  
Vol 23 (5) ◽  
pp. 212-219
Author(s):  
Sergey L. Kolpakov
Keyword(s):  
Social Factors ◽  
Ecological Systems ◽  
Binary Analysis ◽  
Biological Factors ◽  
Immunological Mechanism ◽  
Epidemiological Analysis ◽  
Binary Method ◽  
Epidemic Process ◽  
Natural Factors

Article purpose. To present the binary method of the epidemiological analysis of infectious incidence recommended for the characteristic of factors of social-and-ecological systems her defining. Materials and methods. The method of the binary analysis is developed on the basis of the methods of complex studying of epidemic process used in domestic epidemiology which have received the name “retrospective epidemiological analysis of incidence”. For demonstration long-term and annual dynamics of incidence of chicken pox in Vladivostok from 1997 to 2009 is used. The received results. In the binary analysis consecutive division of cumulative incidence into components is carried out, in the beginning, on the leading approaches characterizing biological, social and natural essence of epidemic process and then, by additional criteria, allows to create the statistical model of the studied object suitable for a research of the global phenomena. From biological factors - participation and a role of the infectious and immunological mechanism. Among natural factors - seasonal and year-round elements; social factors - casual and natural manifestations. In Vladivostok from 1997 to 2009 the share of periodic incidence has made 16,7%, basic incidence - 83,3%. Basic incidence was formed due to year-round incidence (17,8%) and seasonal, the main share. In general 82,2% are the share of seasonal incidence and, it forms both the most part of basic incidence, and all periodic incidence. Share of random factors in incidence not of a bike (7,3%). Incidence is formed by mainly natural factors - 92,7%. Conclusion. Use of a binary method has allowed to create logical model of development of epidemic process at chicken pox in Vladivostok. The accounting of a role of the leading factors will be useful to optimization of epidemiological surveillance. The technique of studying of structural elements of the social-and-ecological systems defining formation of incidence of the population is presented in article. Biological factors are the participation and the role of the infectious and immunological mechanism. Natural factors are seasonal and year-round elements; social factors are casual and natural manifestations.

scholarly journals BINARY METHOD OF THE EPIDEMIOLOGICAL ANALYSIS OF INFECTIOUS INCIDENCE

2018 ◽  
Vol 23 (5) ◽  
pp. 212-219
Author(s):  
Sergey L. Kolpakov
Keyword(s):  
Social Factors ◽  
Ecological Systems ◽  
Binary Analysis ◽  
Biological Factors ◽  
Immunological Mechanism ◽  
Epidemiological Analysis ◽  
Binary Method ◽  
Epidemic Process ◽  
Natural Factors

Article purpose. To present the binary method of the epidemiological analysis of infectious incidence recommended for the characteristic of factors of social-and-ecological systems her defining. Materials and methods. The method of the binary analysis is developed on the basis of the methods of complex studying of epidemic process used in domestic epidemiology which have received the name “retrospective epidemiological analysis of incidence”. For demonstration long-term and annual dynamics of incidence of chicken pox in Vladivostok from 1997 to 2009 is used. The received results. In the binary analysis consecutive division of cumulative incidence into components is carried out, in the beginning, on the leading approaches characterizing biological, social and natural essence of epidemic process and then, by additional criteria, allows to create the statistical model of the studied object suitable for a research of the global phenomena. From biological factors - participation and a role of the infectious and immunological mechanism. Among natural factors - seasonal and year-round elements; social factors - casual and natural manifestations. In Vladivostok from 1997 to 2009 the share of periodic incidence has made 16,7%, basic incidence - 83,3%. Basic incidence was formed due to year-round incidence (17,8%) and seasonal, the main share. In general 82,2% are the share of seasonal incidence and, it forms both the most part of basic incidence, and all periodic incidence. Share of random factors in incidence not of a bike (7,3%). Incidence is formed by mainly natural factors - 92,7%. Conclusion. Use of a binary method has allowed to create logical model of development of epidemic process at chicken pox in Vladivostok. The accounting of a role of the leading factors will be useful to optimization of epidemiological surveillance. The technique of studying of structural elements of the social-and-ecological systems defining formation of incidence of the population is presented in article. Biological factors are the participation and the role of the infectious and immunological mechanism. Natural factors are seasonal and year-round elements; social factors are casual and natural manifestations.

scholarly journals Invasion landscapes as social‐ecological systems: Role of social factors in invasive plant species control

2021 ◽  
Author(s):  
Johanna Yletyinen ◽  
George L. W. Perry ◽  
Olivia R. Burge ◽  
Norman W. H. Mason ◽  
Philip Stahlmann‐Brown
Keyword(s):  
Plant Species ◽  
Social Factors ◽  
Invasive Plant ◽  
Ecological Systems ◽  
Invasive Plant Species ◽  
Social Ecological Systems ◽  
Social Ecological

scholarly journals Measles Epidemic Process in Various Vaccinal Periods

2015 ◽  
Vol 14 (2) ◽  
pp. 80-87 ◽  
Author(s):  
O. V. Tsvirkun ◽  
N. T. Tihonova ◽  
G. V. Yushchenko ◽  
A. G. Gerasimova
Keyword(s):  
Social Factors ◽  
Adult Population ◽  
Biological Factors ◽  
Epidemic Process ◽  
Seasonal Factors ◽  
Measles Vaccination ◽  
First Time ◽  
Factual Data ◽  
External Migration ◽  
Measles Vaccination Coverage

The considerable factual data enabled us for the first time to reveal the peculiarities of measles epidemic process manifestations in different stages of the prophylaxis. It was shown that some determinants of measles epidemic process changed during the period of high measles vaccination coverage of children and adult population: measles mortality was eliminated, the seasonal factors do not influence on the dynamics of epidemic process within a year, fluctuations of measles incidences became stochastic over many last years, the measles ceased to be a children infection. Increasing impact on the epidemic process of measles by social factors and less biological factors, which manifests itself in an increase in the proportion of cases among socially deviant groups, individuals decreed professions. Significant role in the epidemic process play internal and external migration.

scholarly journals Microscopic dynamics modeling unravels the role of asymptomatic virus carriers in SARS-CoV-2 epidemics at the interplay between biological and social factors

2021 ◽  
Author(s):  
Bosiljka Tadić ◽  
Roderick Melnik
Keyword(s):  
Social Factors ◽  
Critical Role ◽  
Critical Threshold ◽  
Model Parameters ◽  
Recent Experience ◽  
Biological Factors ◽  
Dynamics Modeling ◽  
Infection Level ◽  
Virus Survival

The recent experience of SARS-CoV-2 epidemics spreading revealed the importance of passive forms of infection transmissions. Apart from the virus survival outside the host, the latent infection transmissions caused by asymptomatic and presymptomatic hosts represent major challenges for controlling the epidemics. In this regard, social mixing and various biological factors play their subtle, but often critical, role. For example, a life-threatening condition may result in the infection contracted from an asymptomatic virus carrier. Here, we use a new recently developed microscopic agent-based modelling framework to shed light on the role of asymptomatic hosts and to unravel the interplay between the biological and social factors of these nonlinear stochastic processes. The model accounts for each human actor’s susceptibility and the virus survival time, as well as traceability along the infection path. These properties enable an efficient dissection of the infection events caused by asymptomatic carriers from those which involve symptomatic hosts before they develop symptoms and become removed to a controlled environment. Consequently, we assess how their relative proportions in the overall infection curve vary with changing model parameters. Our results reveal that these proportions largely depend on biological factors in the process, specifically, the virus transmissibility and the critical threshold for developing symptoms, which can be affected by the virus pathogenicity. Meanwhile, social participation activity is crucial for the overall infection level, further modulated by the virus transmissibility.

Determinants of the epidemic process of malaria

2020 ◽  
Vol 03 (04) ◽  
pp. 40-42
Author(s):  
Esmira Musa Guliyeva ◽  
◽  
Nargiz Mehman Zeynalova ◽  
Lala Islah Rustamova ◽  
Fatma Idayat Mamedova ◽  
...  
Keyword(s):  
Social Factors ◽  
Epidemiological Surveillance ◽  
Biological Factors ◽  
Epidemic Process ◽  
Sick People ◽  
Source Of Infection ◽  
Malaria Epidemic ◽  
The Republic ◽  
Key Words Malaria ◽  
Artificial Reservoirs

Malaria was found in the regions of the republic and in Baku. Natural and artificial reservoirs are a favorable breeding ground for mosquitoes. Environmental factors influence the activity and the increase and decrease in the number of mosquitoes. The mosquito activity is affected by the smells of sick people. The epidemic process of malaria is influenced by natural, social and biological factors. The epidemiological control of malaria in the country has led to the elimination of the disease. Key words: malaria, epidemic process, source of infection, mosquitoes, determinants: biological, natural and social factors, epidemiological surveillance, elimination

scholarly journals Trends and Clinico-Epidemiological Features of Human Rabies Cases in Bangladesh, 2006–2018

2020 ◽  
Vol 41 (S1) ◽  
pp. s416-s416
Author(s):  
Sumon Ghosh ◽  
Md. Sohel Rana ◽  
Sukanta Chowdhury
Keyword(s):  
Effective Means ◽  
Scale Up ◽  
Traditional Healers ◽  
Human Rabies ◽  
Epidemiological Analysis ◽  
Increasing Trend ◽  
The Mean ◽  
Death Cases ◽  
Death Data

Background: Vaccinating dogs against rabies is an effective means of reducing human rabies. Methods: We analyzed 1,327 clinically diagnosed human rabies deaths and mass dog vaccination (MDV) data during 2006–2018 to quantify the impacts of MDV on human rabies incidence in Bangladesh and a subset of rabies death data (n = 422) for clinico-epidemiological analysis. Results: We found a positive and increasing trend of dog population vaccination (P = .01 and τ = 0.71) and a negative and declining trend (P < .001 and τ = −0.88) of human rabies cases (correlation coefficient, −0.82). Among 422 human rabies death cases, most victims (78%) sought treatment from traditional healers, and 12% received postexposure prophylaxis (PEP). The mean incubation period of rabies cases with exposure sites on the head and neck (35 days) was shorter than the upper limb (mean, 64 days; P = .02) and lower limb (mean, 89 days; P < .01). MDV is effective for reducing human rabies cases in Bangladesh. Conclusions: Creating awareness among the animal bite victims to stop relying on traditional healers rather seeking PEP, addressing the role of traditional healers through an awareness education program in respect to the treatment of dog bites, ensuring availability of PEP, and continuing to scale up MDV can help prevent human rabies deaths.Funding: NoneDisclosures: None

scholarly journals Role of Pirin, an Oxidative Stress Sensor Protein, in Epithelial Carcinogenesis

Biology ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 116
Author(s):  
Francisco Perez-Dominguez ◽  
Diego Carrillo-Beltrán ◽  
Rancés Blanco ◽  
Juan P. Muñoz ◽  
Grettell León-Cruz ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cancer Development ◽  
Biological Factors ◽  
Epithelial Cancers ◽  
Physical Chemical ◽  
Sensor Protein ◽  
Cupin Superfamily ◽  
Functionally Diverse ◽  
Light Chain Enhancer

Pirin is an oxidative stress (OS) sensor belonging to the functionally diverse cupin superfamily of proteins. Pirin is a suggested quercetinase and transcriptional activator of the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) pathway. Its biological role in cancer development remains a novel area of study. This review presents accumulating evidence on the contribution of Pirin in epithelial cancers, involved signaling pathways, and as a suggested therapeutic target. Finally, we propose a model in which Pirin is upregulated by physical, chemical or biological factors involved in OS and cancer development.

scholarly journals Reopening Selves: Phenomenological Considerations on Psychiatric Spaces and the Therapeutic Stance

2021 ◽  
pp. 1-12
Author(s):  
Samuel Thoma ◽  
Isabelle Schwänzl ◽  
Laura Galbusera
Keyword(s):  
Social Factors ◽  
Phenomenological Research ◽  
Social World ◽  
Societal Implications ◽  
Structural Level ◽  
Open Door ◽  
Coercive Treatment ◽  
Psychiatric Institutions ◽  
The Individual

Classical and contemporary phenomenological approaches in psychiatry describe schizophrenia as a disorder of common sense and self-affection. Although taking into account intersubjectivity, this conceptualization still puts forward an individualistic view of the disorder, that is, the intersubjective deficit resides within the person. To overcome such individualism, in this article, we first propose that schizophrenic experience might be understood as arising from a dialectic relation between the self’s loss of openness to the world and the world’s loss of openness to the self. To show the relevance of social factors at the onset of schizophrenic experience, we propose a phenomenological analysis of trigger situations. In the second and main part of this article, we then focus on the implications of these phenomenological insights for the clinical practice: we argue that if schizophrenia is understood as a loss of openness between self and social world, psychiatric institutions should be transformed into spaces that enable a reopening of selves. We first describe <i>enclosing</i> phenomena such as coercive treatment to then, in contrast, present particular forms of <i>open psychiatric spaces</i> such as open door approaches and open dialogue. Besides the institutional-structural level, we also highlight aspects of openness at the intersubjective level of the individual agents, thus particularly emphasizing the role of an open therapeutic stance. We thus speak of (re)opening <i>selves</i> as we believe that the reopening of the patients’ self cannot but be related to and fostered by a reopening of the professionals’ self and stance. We thus argue that openness in the therapeutic stance is key to initiating the further process of recovery, which we describe as a reattunement of selves both at the bodily and narrative level. Last but not least, we sketch out possibilities for future phenomenological research on the question of psychiatric space and draw some broader societal implications.

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