scholarly journals LIPOID NECROBIOSIS: A REVIEW

2018 ◽  
Vol 21 (1) ◽  
pp. 40-44
Author(s):  
L. M Smirnova ◽  
Yulia A. Semenchak ◽  
L. A Panchenko

Necrobiosis lipoidica (syn.: skin disclipines, diabetic lipoid necrobiosis of Urbach, disease Oppenheim--Urbach, mottled atrophic necrobiosis diabetic dermatitis Oppenheim, pseudocertainty symmetrical chronic granulomatous disease Gottron, etc.) - is a chronic granulomatous disease characterized by multifactorial genesis in the background of immunological changes, disorders of carbohydrate and lipid metabolism and pathology of microcirculatory processes. This article presents a review of the current literature on the etiology and pathogenesis, clinical picture, classification, differential diagnosis of disease and on methods of conducting and treatment of patients.

2017 ◽  
Vol 8 (2) ◽  
pp. 87 ◽  
Author(s):  
Daniel Kotlarz ◽  
Odul Egritas Gurkan ◽  
Zehra Sule Haskologlu ◽  
Ozgur Ekinci ◽  
Aysel Aksu Unlusoy ◽  
...  

2016 ◽  
Vol 56 (2) ◽  
pp. 80-86
Author(s):  
N. A. Kravchun ◽  
I. V. Chernyavskay ◽  
O. V. Zemlianitsyna ◽  
I. P. Romanova

This article describes a clinical case of Lawrence lipoatrophic diabetes patient who was born in 1963. The differential diagnosis with gipermuskulin lipodystrophy. Diagnostic criteria of Lawrence lipoatrophic diabetes were shown. They are specific patient’s appearance big changes in carbohydrate and lipid metabolism. The dynamics of the patient’s status on the background of symptomatic therapy was evaluated.


Author(s):  
Gözde Emel Gökçek ◽  
Özge Şeyda Şaka ◽  
Emine Çölgeçen ◽  
Murat Borlu ◽  
Özlem Canöz

Necrobiosis lipoidica is a rare chronic granulomatous disease that has historically been associated with diabetes mellitus, but recently it is thought to be secondary to microangiopathic changes. We report a necrobiosis lipoidica case of a five-year-old girl with diabetes since the age of two, because it is exceptionally unusual in pediatric diabetes. Necrobiosis lipoidica should be considered in pediatric patients with slowly expanded erythematous plaques and patches. This will help protect the patient from other important diabetic microangiopathic complications, such as nepropathy and retinopathy and also malignant progression, such as squamous cell carcinoma.


Author(s):  
Kashish Narula ◽  
Narendra Kumar Dara ◽  
Shyam Lal Meena

Background: Thyroid hormones influence nearly all major metabolic pathways. Their most obvious and well-known action is the increase in basal energy expenditure obtained by acting on protein, carbohydrate and lipid metabolism. The lipid metabolism is more influenced by the thyroid hormone. Methods: A cross-sectional study was conducted on 100 patients with suspicion of thyroid disorders were taken as cases. One hundred patients with normal thyroid profile and no history of other chronic diseases were taken as control group. Results: The serum TC, TG and LDL levels in hypothyroid individuals (both overt and subclinical) were significantly higher than euthyroid subjects but the levels were comparable between hyperthyroid and euthyroid group. Conclusion: Dyslipidemias are associated with thyroid disorders, so biochemical screening for thyroid dysfunction in all dyslipidemic patients. Therefore, patients presenting with dyslipidemia are recommended for investigation to explore thyroid dysfunction. Keywords: Thyroid profile, Total cholesterol, Triglycerides and LDL


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