scholarly journals Evaluation of Adherence to Oral Hypoglycemic Agent Prescription in Patients with Type 2 Diabetes

2020 ◽  
Vol 16 (1) ◽  
pp. 41-45
Author(s):  
Mahtab Irani ◽  
Mohammad Sarafraz Yazdi ◽  
Meisam Irani ◽  
Sina Naghibi Sistani ◽  
Sahar Ghareh
Keyword(s):  
Type 2 Diabetes ◽  
Medication Adherence ◽  
Hemoglobin A1c ◽  
Statistical Tests ◽  
Personal Characteristics ◽  
Adherence To Treatment ◽  
Adherence To Medication ◽  
Treatment Of Diabetes ◽  
Global Health Problem

BACKGROUND: Diabetes is a global health problem that has affected more than 400 million people worldwide. Adherence to treatment is considered to be one of the most impor tant and deterministic factors in the treatment of diabetes. This study investigates medication adherence and factors af fecting it in patients with type 2 diabetes. METHODS: This crosssectional study investigated 136 patients with type 2 diabetes in 2018-2019. Data collection was done using a checklist that included information on personal characteristics, medication, and healthcare. The collected data were analyzed by statistical tests in SPSS 25 software. RESULTS: 79.4% of the patients adhered to prescribed medication. Medication adherence had no significant relationship with taking other dr ugs, fasting blood sugar (FBS), and the daily number of hypoglycemic tablets (p > 0.05). However, adherence to medication was significantly associated with age, gender, income, hemoglobin A1c, medication period, and hypoglycemia (p < 0.05). CONCLUSIONS: Higher levels of adherence werè obser ved among females aged below 60 years, with higher income, a hemoglobin A1c level below 7%, a medication period of less than 10 years, and among patients without hypoglycemia. Regarding drug type, adherence levels were lower in people taking glibenclamide.

scholarly journals Gut microbiota imbalances in Tunisian participants with type 1 and type 2 diabetes mellitus

2019 ◽  
Vol 39 (6) ◽  
Author(s):  
Meriem Fassatoui ◽  
Mireia Lopez-Siles ◽  
Diana A. Díaz-Rizzolo ◽  
Haifa Jmel ◽  
Chokri Naouali ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Multivariate Analysis ◽  
Gut Microbiota ◽  
Glycated Hemoglobin ◽  
Statistical Tests ◽  
Treatment Of Diabetes

Abstract Gut microbiota plays an important role in the regulation of the immune system and host’s metabolism. We aimed to characterize the gut microbiota of Tunisian participants with and without diabetes. We enrolled ten participants with type 1 diabetes mellitus (T1DM), ten patients with type 2 diabetes mellitus (T2DM), and 11 subjects without diabetes. Bacteria was quantified in fecal samples by quantitative PCR (qPCR). Statistical tests and multivariate analysis were performed using RStudio program. Results showed that the proportions of Firmicutes, Akkermansia muciniphila, and Faecalibacterium prausnitzii (P≤0.041), as well as, the ratio Firmicutes/Bacteroidetes decreased in participants with T1DM compared with those without diabetes (p = 0.036). Participants with T2DM presented a reduction in the amounts of A. muciniphila and F. prausnitzii compared with those without diabetes (P≤0.036). Furthermore, A muciniphila is negatively correlated with glucose level (P=0.022) and glycated hemoglobin (HbA1c) (P=0.035). Multivariate analysis revealed that participants with diabetes formed a cluster apart compared with those without diabetes. In conclusion the gut bacteria of Tunisian participants with diabetes was altered. The gut bacterial profile, especially the distribution of A muciniphila in participants with diabetes was affected by glycemic dysregulation. The investigation of the gut microbiota may help clinicians to improve diagnosis and treatment of diabetes and its complications.

Medication Adherence and Associated Hemoglobin A1c in Type 2 Diabetes

2004 ◽  
Vol 38 (9) ◽  
pp. 1357-1362 ◽  
Author(s):  
Kimberley Krapek ◽  
Kathleen King ◽  
Susan S Warren ◽  
Karen G George ◽  
Dorothy A Caputo ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Medication Adherence ◽  
Hemoglobin A1c

scholarly journals Assessment of medication adherence and quality of life among patients with type 2 diabetes mellitus in a tertiary hospital in Kelantan, Malaysia

2021 ◽  
Vol 1 (2) ◽  
pp. 79-86
Author(s):  
Nazmi Liana Azmi ◽  
Nurul Aida Md Rosly ◽  
Hock Chun Tang ◽  
Anis Fariha Che Darof ◽  
Nor Dini Zuki
Keyword(s):  
Quality Of Life ◽  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Medication Adherence ◽  
Life Questionnaire ◽  
Adherence To Medication ◽  
The Mean

Introduction: Previous studies have reported the relationship between medication adherence and quality of life are interrelated. However, many of the results were found to be conflicting. This study aimed to assess the level and association of medication adherence and quality of life among type 2 diabetes mellitus patients in Raja Perempuan Zainab II Hospital, Kelantan, Malaysia. Materials and methods: A cross-sectional survey was conducted among adult type 2 diabetes mellitus patients on treatment for over 1 year using convenience sampling at outpatient.  Medication Compliance Questionnaire (MCQ) and revised Diabetes Quality of Life Questionnaire (DQOL) instrument were self-administered to eligible subjects. Data were analysed using GNU PSPP version 0.8.5 and reported for descriptive statistics as well as correlation of both parameters. Results: A total of 200 patients were recruited and they were mostly at the age of 40 to 60 years old. The mean (SD) score for MCQ was 26.0 (1.6) with the majority of them were non-adherent (55.0%, n=110). The mean (SD) score for overall revised DQOL instrument was 25.5 (8.9) while each domain of “satisfaction”, “impact” and “worry” had mean (SD) scores of 12.0 (5.0), 7.7 (3.4) and 5.9 (2.7), respectively. The scores obtained were only approximately half of the possible range of scores for QoL. There was no significant correlation between total score of medication adherence and quality of life when tested using Pearson’s correlation (r=-0.083, p=0.240). Independent t-test also demonstrated no significant relationship between medication adherence status and quality of life (p=0.883). Conclusion: Type 2 diabetes mellitus patients in our setting had unsatisfactory adherence but exhibited acceptable quality of life. We observed that both variables were not associated with one another. Further research is warranted to identify potential factors affecting non-adherence to medication.

scholarly journals A Feasibility Pilot Trial of a Peer-support Educational Behavioral Intervention to Improve Diabetes Medication Adherence in African Americans

2021 ◽  
Author(s):  
Olayinka Shiyanbola ◽  
Martha Maurer ◽  
Mattigan Mott ◽  
Luke Schwerer ◽  
Nassim Sarkarati ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Medication Adherence ◽  
African Americans ◽  
Effect Size ◽  
Self Efficacy ◽  
Hemoglobin A1c ◽  
The United States ◽  
Post Intervention ◽  
Phone Calls

Abstract BackgroundAfrican Americans are twice as likely to die from diabetes, compared to other racial and ethnic groups in the United States. Poor adherence to diabetes medications is common among African Americans and contributes to these disproportionally worse outcomes. A pilot study was conducted to determine the feasibility and acceptability of a peer-supported intervention targeting diabetes and medication beliefs, communication, and self-efficacy skills to enhance medication adherence among African Americans with type 2 diabetes. MethodsBased on the extended self-regulatory model and information-motivation-behavioral skills model, this intervention was piloted using a single group pre/post-intervention study design at two sites. Seventeen African Americans who self-reported as adherent to diabetes medicines (ambassadors), were paired with 22 African Americans with self-reported poor medication adherence (buddies). Measures assessed at baseline and one-month post-intervention included glycemic control (hemoglobin A1c), self-reported medication adherence, diabetes beliefs, concerns about diabetes medicines, and diabetes self-efficacy. Wilcoxon signed rank tests assessed for differences in mean scores of outcome variables at baseline compared with 3-months follow-up. Semi-structured 60-minute interviews were conducted with each buddy to explore their acceptability of the intervention. To ensure the rigor of the qualitative data, we focused on analytic criteria such as credibility, confirmability, and transferability.ResultsMost buddies and ambassadors were female and about 56 years old. Feasibility outcomes included recruitment success rates of 73% for buddies and 85% for ambassadors relative to our goals. Retention rate for hemoglobin A1c and medication adherence outcome assessment was 95% for buddies. Both buddies and ambassadors had excellent intervention adherence, with buddies having a mean attendance of 7.76 out of 8 sessions/phone calls and ambassadors completing > 99% of the 105 intervention calls with Buddies. Results showed a signal of change in hemoglobin A1c (effect size = 0.14) and medication adherence (effect size = 0.35) among buddies, reduction in buddies’ negative beliefs about diabetes and an increase in necessity beliefs of diabetes medicines. Summative interviews with buddies showed they valued ambassador’s encouragement of self-management behaviors. ConclusionsResults support conduct of an efficacy trial to address medication adherence for African Americans with type 2 diabetes using a peer-supported tailored intervention.

scholarly journals Diabetic Patients’ Quality of Life and Their Relationship in Compliance with Antidiabetic Treatment. Case Study of Patients in a Public Hospital in Greece

2020 ◽  
Vol 17 ◽  
Keyword(s):  
Quality Of Life ◽  
Type 2 Diabetes ◽  
Diabetes Management ◽  
Medical Science ◽  
Diabetic Patients ◽  
Adherence To Treatment ◽  
Adherence To Medication ◽  
Antidiabetic Treatment

Background & Aim: Diabetes is a chronic disease that affects nearly half a million people worldwide. Although advances in technology and medical science have made diabetes management easier today, self-care and adherence to treatment (medication, diet, exercise, etc.) remain a major challenge for diabetic patients. The purpose of this study is to study the quality of life of patients with type 2 diabetes, their levels of compliance with antidiabetic treatment, and the relationship between the two. Methods & Materials: The present work followed the quantitative approach. A well-structured and reliable questionnaire used in a previous study was distributed to patients with type 2 diabetes mellitus. The results were analysed in SPSS statistical program and the correlation between antidiabetic treatment and quality of life was examined using Pearson coefficient. Results: The study involved 165 patients with type 2 diabetes who were hospitalized at the General Hospital of Messinia. Among the dimensions of adherence to treatment, only personal care behaviour (p <0.05) and adherence to care (p <0.05) were significantly and positively correlated with the physical quality of life health. Conclusion: Patients with type 2 diabetes have moderate the low quality of life, in line with previous research findings. Lower extremity care compliance was associated with the quality of life of diabetic patients with physical health, although previous studies have generally found that compliance with a diet regimen as well as adherence to medication is associated with the quality of life of diabetic patients. Future research needs to address the same issue by taking larger and more representative samples.

Factors Associated with Poor Hemoglobin A1c Control in Patients with Type 2 Diabetes

2019 ◽  
Vol 15 (2) ◽  
pp. 164-170 ◽  
Author(s):  
Salam Alqudah ◽  
Anan S. Jarab ◽  
Eman A. Alefishat ◽  
Fadia Mayyas ◽  
Maher Khdour ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Medication Adherence ◽  
Glycemic Control ◽  
Hemoglobin A1c ◽  
Diabetes Management ◽  
Blood Glucose Control ◽  
Clinical Pharmacy Service ◽  
Diabetes Clinic ◽  
Factors Associated

Background: The limited implementation of clinical pharmacy service programs and the lack of studies identifying barriers to achieve blood glucose control have all attributed to the increased proportion of type 2 diabetes patients who have poor glycemic control in Jordan. Objective: To explore factors associated with higher HbA1c in patients with type 2 diabetes in Jordan. Methods: Variables including socio-demographics, disease and treatment factors were collected from171 patients with type2 diabetes at an outpatient diabetes clinic in Amman. Validated questionnaires were used to assess medication adherence, self-care activities, diabetes knowledge and healthrelated quality of life in addition to data collected from medical records. After the single-predictor analysis, stepwise linear regression was performed to develop a model with variables that best predicted hemoglobin A1c. Results: Medication adherence was inversely associated with HbA1c values (β = -0.275; t = 2.666; P < 0.01), indicating better glycemic control. Receiving insulin therapy was also associated with less HbA1c values and better glycemic control (β = - 0.184; t = 2.080; P < 0.05). Patients who had one or more comorbid conditions (β = 0.215; t = 2.264; P < 0.05) and those with longer diabetes duration (β = 0.092; t = 1.339; P < 0.05) were found to have significantly higher HbA1c values. Conclusion: Emphasizing medication adherence, particularly for patients with longer duration of diabetes and those with multiple comorbid diseases should be strongly considered in future diabetes management programs implemented to improve glycemic control in patients with type 2 diabetes.

scholarly journals Pendidikan Kesehatan Tentang Kepatuhan Minum Obat Pada Pasien Diabetes Melitus Tipe 2 Di Rumah Sakit TK II Putri Hijau Medan

2021 ◽  
Vol 1 (3) ◽  
pp. 252-263
Author(s):  
Nurul Fadhilah ◽  
Khairunnisa Batubara
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Medication Adherence ◽  
Health Education ◽  
Scientific Paper ◽  
Peripheral Tissues ◽  
Adherence To Medication ◽  
Diabetes Melitus

 ABSTRACT: HEALTH EDUCATION ON MEDICINE COMPLIANCE IN TYPE 2 DIABETES MELLITUS PATIENTS IN TK II PUTRI GREEN HOSPITAL, MEDAN Introduction: Type 2 diabetes mellitus is a hyperglycemic condition that occurs even though endogenous insulin is available where the insulin levels produced are damaged by insulin resistance in peripheral tissues. Actions that can be given to clients with type 2 diabetes mellitus that can be chosen to overcome the problem of knowledge about medication adherence are by providing health education. Health education is an activity that educates the public about health by presenting the information.Purpose: The purpose of this scientific paper is to carry out education about medication adherence in patients with Type 2 Diabetes Mellitus at the Tk II Putri Hijau Hospital, Medan.Methods: This research method is a descriptive study with a health education study design regarding medication adherence in patients with type 2 diabetes mellitus using a process approach. This study was conducted on two patients with the same diagnosis of type 2 diabetes mellitus in recurrent patients who do not adhere to medication.Results: The results of the health education research given about medication adherence can increase changes in a healthy life.Conclusion: For further researchers to explore more about medication adherence Keywords: Health education, adherence to medication, Type 2 diabetes  INTISARI: PENDIDIKAN KESEHATAN TENTANG KEPATUHAN MINUM OBAT PADA PASIEN DIABETES MELITUS TIPE 2 DI RUMAH SAKIT TK II PUTRI HIJAU MEDAN  Pendahuluan: Diabetes Melitus tipe 2 adalah suatu kondisi hiperglikemia yang terjadi meski tersedia insulin endogen dimana kadar insulin yang dihasilkan dirusak oleh resistensi insulin dijaringan perifer. Tindakan keperawatan yang bisa diberikan kepada klien dengan Diabetes mellitus tipe 2 yang dapat dipilih untuk mengatasi masalah kurang pengetahuan tentang kepatuhan minum obat adalah dengan memberikan pendidikan kesehatan. Pendidikan kesehatan adalah suatu kegiatan yang mendidik masyarakat tentang kesehatan dengan pemaparan informasi.Tujuan: Tujuan dari Karya Tulis Ilmiah ini untuk melaksanakan pendidikan kesehatan tentang kepatuhan minum obat pada pasien Diabetes Melitus Tipe 2 Di Rumah Sakit Tk II Putri Hijau Medan.Metode: Metode penelitian ini adalah penelitian deskriptif dengan rancangan studi pendidikan kesehatan tentang kepatuhan minum obat pada pasien diabetes mellitus tipe 2 menggunakan pendekatan proses keperawatan. Penelitian ini dilakukan pada dua orang pasien dengan diagnosa yang sama dengan masalah penyakit diabetes mellitus tipe 2 pada pasien berulang yang tidak patuh minum obat.Hasil: Hasil penelitian diperoleh pendidikan kesehatan yang diberikan tentang kepatuhan minum obat dapat meningkatkan perubahan hidup sehat.Kesimpulan: Untuk peneliti selanjutnya hendaknya mendalami lagi tentang kepatuhan minum obat Kata kunci : Pendidikan kesehatan, Kepatuhan minum obat,  DM Tipe 2 

scholarly journals Use of Brief Messages Based on Behavior Change Techniques to Encourage Medication Adherence in People With Type 2 Diabetes: Developmental Studies (Preprint)

2019 ◽  
Author(s):  
Yvonne Kiera Bartlett ◽  
Andrew Farmer ◽  
Rustam Rea ◽  
David P French
Keyword(s):  
Type 2 Diabetes ◽  
Medication Adherence ◽  
Behavior Change ◽  
Health Care Professionals ◽  
Text Messages ◽  
Test Theory ◽  
Behavior Change Techniques ◽  
Adherence To Medication ◽  
Adherence Support

BACKGROUND Brief messages are a promising way to improve adherence to medication for people with type 2 diabetes. However, it is often unclear how messages have been developed and their precise content, making it difficult to ascertain why certain messages are successful and some are not. OBJECTIVE The goal of the research was to develop messages that have proven fidelity to specified evidence-derived behavior change techniques (BCTs) and are acceptable to people with type 2 diabetes. METHODS Four studies were conducted: (1) a workshop (n=21) where behavioral change researchers and health care professionals developed messages based on specific BCTs or beliefs or concerns related to taking medication, (2) a focus group study with people with type 2 diabetes (n=23) to assess acceptability of the approach, (3) a survey to ascertain the acceptability of a subset of messages to people with type 2 diabetes (n=61) and, (4) a survey with behavior change researchers to assess the fidelity of a subset of messages to their intended BCT (n=18). RESULTS In study 1, 371 messages based on 38 BCTs and beliefs/concerns were developed. Workshop participants rated BCTs to be relevant to medication adherence (mean 7.12/10 [SD 1.55]) and messages to have good fidelity (mean 7.42/10 [SD 1.19]). In study 2, the approach of providing medication adherence support through text messages was found to be acceptable. In study 3, mean acceptability of all BCTs was found to be above the midpoint (mean 3.49/5 [SD 0.26]). In study 4, mean fidelity for all BCTs was found to be above the midpoint (mean 7.61/10 [SD 1.38]). CONCLUSIONS A library of brief messages acceptable to people with type 2 diabetes and representative of specific evidence-derived BCTs was developed. This approach allowed brief messages to be developed with known content that can be used to test theory.

scholarly journals Patterns of adherence to management among patients with type 2 diabetes mellitus in South-South Region of Nigeria

2015 ◽  
Vol 03 (02) ◽  
pp. 115-119 ◽  
Author(s):  
Oyewole Emmanuel ◽  
Agofure Otovwe
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Dietary Treatment ◽  
Public Healthcare ◽  
Adherence To Treatment ◽  
Patient Counseling ◽  
Cross Sectional ◽  
Adherence To Medication

Abstract Aims: The study investigated the pattern of adherence to medication and dietary treatment among type 2 diabetes mellitus patients. Settings and Design: A cross-sectional study conducted among 350 consented patients with type 2 diabetes mellitus from a secondary public healthcare facility. Materials and Methods: A semistructured questionnaire was interviewer-administered to obtain information on respondents′ sociodemographic characteristics, level of adherence to medication and dietary treatment, and suggestions on ways of improving adherence to treatment. Descriptive statistics, chi-square test, and logistic regression were used to analyze the data with level of significance set at 0.05. Results: Mean age of respondents was 57.9 ± 9.8 years, 60.9% were females and 78.0% were married. Some respondents exhibited total adherence to medication (58.9%) and dietary (67.4%) treatment, respectively. Determinants of nonadherence to medication and dietary treatment include using alternative traditional medicine (herbs) for the treatment of the disease (odds ratio (OR) = 0.42, 95% confidence interval (CI) = 0.568-1.916) and consuming foods more than recommended quantity (OR = 6.28, 95% CI = 3.919-10.083). One of the suggested ways by the respondents to improve adherence to treatment was self-discipline (46.9%). Lack of awareness on the seriousness of the disease (42.6%) was a major challenge confronting patients with type 2 diabetes mellitus. Creation of awareness on the seriousness of the disease was suggested by 39.1% of respondents. Conclusions: Use of alternative medicine (herbs) and eating more than the recommended quantity of foods remain a challenge among patients with type 2 diabetes mellitus. Comprehensive health promotion and education strategies including patient counseling on diabetes care with emphasis on adherence to medication and dietary treatment regimen should be organized regularly for diabetes patients.

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