scholarly journals ФАРМАКОЛОГИЧЕСКИЕ СВОЙСТВА РАСТИТЕЛЬНЫХ КОМПОЗИЦИЙ ЭКСТРАКТОВ RHAPONTICUM CARTHAMOIDES И ШРОТА VACCINIUM OXYCOCCUS

Author(s):  
Д.А. Халикова ◽  
◽  
С.В. Аньков ◽  
Т.Г. Толстикова ◽  
◽  
...  
2021 ◽  
Vol 11 (6) ◽  
pp. 2555
Author(s):  
Lyudmila Asyakina ◽  
Svetlana Ivanova ◽  
Alexander Prosekov ◽  
Lyubov Dyshlyuk ◽  
Evgeny Chupakhin ◽  
...  

This work aims to study the qualitative composition of biologically active substance (BAS) extracts in vitro callus, cell suspension, and root cultures of the medicinal plant Rhaponticum carthamoides. The research methodology is based on high-performance liquid chromatography, and 1H nuclear magnetic resonance (NMR) spectra, to study the qualitative and quantitative analysis of BAS. The results of the qualitative composition analysis of the dried biomass extracts of in vitro callus, cell suspension and root cultures showed that the main biologically active substances in the medicinal plant Rhaponticum carthamoides are 2-deoxy-5,20,26-trihydroxyecdyson (7 mg, yield 0.12%), 5,20,26-trihydroxyecdyson 20,22-acetonide (15 mg, yield 0.25%), 2-deoxy-5,20,26-trihydroxyecdyson 20,22-acetonide (6 mg, yield 0.10%), 20,26-dihydroxyecdyson 20,22-acetonidecdyson 20,22-acetonide (5 mg, yield 0.09%), and ecdyson 20,22-acetonide (6 mg, yield 0.10%). In the future, it is planned to study the antimicrobial, antioxidant, and antitumor activity of BAS of extracts of in vitro callus, cell suspension, and root cultures of the medicinal plant Rhaponticum carthamoides, for the production of pharmaceuticals and dietary supplements with antitumor, antimicrobial and antioxidant effects.


2019 ◽  
Vol 49 (5) ◽  
pp. 52-60
Author(s):  
V. A. Voloshin ◽  
D. A. Matolinets ◽  
N. A. Morozkov ◽  
G. P. Maysak

The results of studies of the use of rhaponticum carthamoides for feeding dairy cows are presented. The experiment was carried out on Holstein cows of black-and-white breed in Perm Territory. Vitaminherbal fl our from green mass of rhaponticum carthamoides at a dose of 0.4 and 1.0 kg per head per day in the period of 10-16 days before calving and in the fi rst 30 days of lactation was introduced into the feeding rations of two experimental groups of cows. High sugar content in rhaponticum carthamoides (from 4.15 to 11.2% in dry matter and metabolic energy from 10.87 to 12.12 MJ/ kg) was noted. In the studied material from this plant, the content of the 20-hydroxyecdysone was 0.49% of active ingredients in the dry matter of the product at a rate of 0.25%. The introduction of rhaponticum carthamoides in the diet of feeding animals contributed to the increase in the intensity of metabolic processes in the body. A gradual increase in cholesterol levels in all experimental groups was noted. The most signifi cant growth was observed in cows of the second experimental group by 0.82 mmol / l or 29.50% (p <0.01). Compared with the fi rst experimental group, the increase was 0.13 mmol / l or 5.2%, and the control group – 0.36 mmol / l or 14.17%. Stimulation of metabolic processes in the body of cows of the experimental groups had a positive impact on reproduction, which was manifested in the reduction of the service period duration, compared with the control group.


2021 ◽  
pp. 179-209
Author(s):  
Ugiloy Yusufovna Yusupova ◽  
Nurmurod Sheralievich Ramazonov ◽  
Vladimir Nikolaevich Syrov ◽  
Shomansur Shosaidovich Sagdullaev

Author(s):  
K. Subramanya Sastry ◽  
Bikash Mandal ◽  
John Hammond ◽  
S. W. Scott ◽  
R. W. Briddon

2016 ◽  
Vol 2016 ◽  
pp. 1-10 ◽  
Author(s):  
Ewa Skała ◽  
Patrícia Rijo ◽  
Catarina Garcia ◽  
Przemysław Sitarek ◽  
Danuta Kalemba ◽  
...  

The essential oils were isolated by hydrodistillation from the hairy roots (HR) and roots of soil-grown plants (SGR) of Rhaponticum carthamoides and were analyzed by GC-MS method. In the both essential oils 62 compounds were identified. The root essential oils showed the differences in the qualitative and quantitative composition. The sesquiterpene hydrocarbons (55–62%) dominated in both essential oils. The major compounds of HR essential oil were cyperene, 13-norcypera-1(5),11(12)-diene, and cadalene while aplotaxene, nardosina-1(10),11-diene, and dauca-4(11),8-diene dominated in SGR essential oil. Both essential oils showed antibacterial activity especially against Enterococcus faecalis (ATCC 29212) and Pseudomonas aeruginosa (ATCC 27853) (MIC value = 125 µg/mL). HR and SGR essential oils also decreased the expression of IL-1β, IL-6, and TNF-α and the ROS level in LPS-treatment astrocytes. This is the first report to describe the chemical composition of R. carthamoides essential oil from hairy roots, its protective effect against LPS-induced inflammation and ROS production in astrocytes, and its antimicrobial potential. The results show that R. carthamoides hairy roots may be a valuable source of the essential oil and may be an alternative to the roots of soil-grown plants.


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