scholarly journals Hubungan antara Kadar Feritin dengan Malondialdehyde pada Pasien Talasemia β Mayor di RSD dr. Soebandi Jember

2020 ◽  
Vol 7 (1) ◽  
pp. 52
Author(s):  
Trinita Diyah Permatasari ◽  
Rini Riyanti ◽  
Desie Dwi Wisudanti

Repeated blood transfusions, increased iron absorption, and ineffective erythropoiesis in major β thalassemia patients lead to iron overload characterized by elevated ferritin levels. Free iron will catalyze reactive oxygen species (ROS) formation by Fenton reaction that cause oxidative stress. Malondialdehyde (MDA) is the lipid peroxidation end product used to measure the oxidative stress. This study aimed to determine the correlation between ferritin levels and MDA levels in major β thalassemia patients at dr. Soebandi Hospital Jember. An analitic observational study with cross sectional study design which the subjects were 15 patients with major β thalassemia in the Pediatric Department at dr. Soebandi Hospital Jember who met inclusion and exclusion criteria. Ferritin levels measured by Enzyme-Linked Fluorescent Immuno Assay (ELFA) method and MDA levels measured by Thiobarbituric Acid Reactive Substances (TBARS) method using spectrophotometer at 535 nm. Data was analyzed with Shapiro Wilk normality test and Pearson correlation test. The mean of ferritin levels was 3540,46±3925,37 ng/mL and MDA levels was 4,77±2,03 nmol/mL. The result showed that there is strong positive correlation between ferritin levels and MDA levels with p value=0,001 and r=0,786 in major β thalassemia patients at dr. Soebandi Hospital Jember.

2020 ◽  
Vol 11 (2) ◽  
pp. 175
Author(s):  
Nauri Anggita Temesvari ◽  
Desmayanti Br Subakti

<p>Job satisfaction in hospitals was needed to improve the performance to be achieved by the hospital. Job satisfaction could have an impact on whether or not happy employees do their jobs. One factor that affects job satisfaction is work facilities. Job satisfaction in the PGI Cikini Hospital medical record unit looks not good. This could be seen from the absence of employees by 15%. The problem complained by employees was the lack of work equipment provided by hospitals. The purpose of this study was to analyze the correlation between work facilities and job satisfaction at medical record unit PGI Cikini Hospital. This study used a cross-sectional study design with a total sample of all employees of the PGI Cikini Hospital Medical Record Unit with a total of 30 persons. The study was conducted from March to December 2019. The instrument used was a questionnaire. Analysis conducted descriptively to display the data of each variable and also analytically with Pearson correlation test to analyze the relationship between work facilities and job satisfaction. There was a strong, positive correlation between work facilities and job satisfaction (rxy=0,609). Work facilities and job satisfaction have a statistically significant linear relationship (p-value 0,000). There was a correlation between work facilities and job satisfaction at medical record unit PGI Cikini Hospital.</p>


Author(s):  
Evin Novianti ◽  
Noer Aeni Zam Zam Mia

Abstrak Latar belakang: Masa remaja dianggap sebagai transisi antara masa kanak-kanak ke masa dewasa yang ditandai dengan perubahan fisik atau biologis, kognitif dan psikososial. Perubahan yang dialami selama masa remaja berbagai masalah internal dan eksternal pada remaja yang dapat berupa stres, salah satunya adalah bullying. Dukungan sosial dibutuhkan remaja untuk menjalani masa transisi. Studi ini ditujukan untuk menilai pengaruh dukungan keluarga terhadap tingkat kecemasan pada remaja yang mengalami bullying di SMA Negeri 7 Jakarta. Metode: Studi Cross Sectional dengan simple random sampling dari Februari sampai Juni 2020 di SMA Negeri 7 Jakarta. Jumlah sampel penelitian 148 responden yang diwawancarai secara daring menggunakan google form. Uji Korelasi Pearson dan uji T-Independent digunakan untuk menganalisis data. Hasil: Studi ini menemukan pengaruh hubungan dukungan keluarga dengan tingkat kecemasan pada remaja pelaku bullying di SMA Negeri 7 Jakarta (p value=0,000). Kesimpulan: Perawat dapat memberikan edukasi terkait kecemasan yang dialami remaja dengan bullying, sekolah diharapkan dapat memberikan bimbingan konseling kepada siswa yang menjadi korban dan pelaku bullying, dan bagi keluarga khususnya orang tua diharapkan dapat meningkat. dukungan untuk anak remaja mereka.   The Effect of Family Support on Anxiety Levels in Teenagers Experience Bullying Abstract Background: Adolescence is considered as a transition between childhood to adulthood characterized by physical or biological, cognitive and psychosocial changes. Changes experienced during adolescence are various internal and external problems in adolescents which can be in the form of stress, one of which is bullying. Social support is needed by adolescents to undergo a transition period. This study aimed to determine the effect of family support and anxiety levels in adolescents with bullying at SMA Negeri 7 Jakarta. Methods: A cross sectional study was done from February to June 2020 at SMA Negeri 7 Jakarta. Total 148 students were selected using simple random sampling who were interviewed online using google form. Pearson Correlation Test and T-Independent test was performed to analysed the data. Results: The results of this study found that there was a relationship between family support and the level of anxiety among bullying adolescents at SMA Negeri 7 Jakarta (p value = 0,000). Conclusion: Nurses can provide education regarding the anxiety experienced by adolescents with bullying, schools are expected to provide counseling guidance to students who are victims and perpetrators of bullying, and for families, especially parents, it is expected to increase. support for their teenagers.


2018 ◽  
Vol 4 (1) ◽  
pp. 18
Author(s):  
Amalia Nur Zahra ◽  
Rini Riyanti ◽  
Elly Nurus Sakinah

Repeated  blood  transfusions in patient with Major Beta Thalassemia  leads  to  iron  overload  marks by the increased of serum ferritin levels. Free iron caused the change of H2O2 to oxidants by fenton reaction and caused oxidative stress. These oxidants will be counteracted by GSH as antioxidants. The purpose of this study was to investigate the correlation between ferritin levels with GSH in patients with major beta thalassemia in RSD dr. Soebandi hospital Jember. The samples of this study are fifteen (15) patients age 1-18 years who were regularly transfused. Serum ferritin levels were measured by Enzyme-Linked Fluorescent Immuno Assay (ELFA) and plasma GSH levels were measured by Ellman method. Data was analyzed using Pearson correlation test. Serum feritin levels were increased in Major Beta Thalassemia children with average of 3540,46 ± 3925,37 ng/mL. The  mean of  GSH is 10,46 ± 2,58 µmol. We found significant and negative correlation between serum ferritin and GSH with p value=0,000 and r=-0,951 in Major beta thalassemia patient at RSD dr. Soebandi Jember. Keywords: Thalassemia, Oxidative stress, Feritin, GSH


e-GIGI ◽  
2014 ◽  
Vol 2 (2) ◽  
Author(s):  
Triska Yolanda Worang ◽  
Damajanti H. C. Pangemanan ◽  
Dinar A. Wicaksono

Abstract: Domain knowledge is very important for the formation of one's actions. Knowledge of parents is very important in the formation of the underlying behaviors that support or do not support the oral hygiene of children. Good oral hygiene will make healthy teeth and surrounding tissues. This study aims to analyze the relationship between the level of knowledge of parent swith achild's dental and oral hygiene in kinder garten Tunas Bhakti Manado. The research used the descriptive analytical study with cross sectional approach. The experiment was conducted in a kinder garten classroom Shoots Bhakti Manado. The sample in this study all children in kinder garten preschool Tunas Bhakti Manado as many as 70 children examined OHI-S and as many as 12 questions questionnaire for the elderly. Sampling technique with a total sampling method.The results of this study indicate that parental knowledge about dental and oral hygiene in either category by 45.7% with oral hygiene status of children included in the medium category at 65.7%. Based on the results obtained Pearson correlation test p value of 0.020 (p <0.05). It can be concluded that there is a relationship between the level of knowledge of parents with children's dental and oral hygiene in kindergarten Tunas Bhakti Manado. Keywords: knowledge, OHI-S, preschoolers.   Abstrak: Pengetahuan merupakan domain yang sangat penting untuk terbentuknya tindakan seseorang.Pengetahuan orang tua sangat penting dalam mendasari terbentuknya perilaku yang mendukung atau tidak mendukung kebersihan gigi dan mulut anak. Kebersihan mulut yang baik akan membuat gigi dan jaringan sekitarnya sehat. Penelitian ini bertujuan untuk menganalisis hubungan antara tingkat pengetahuan orang tua dengan kebersihan gigi dan mulut anak di TK Tunas Bhakti Manado.Jenis penelitian yang digunakan yaitu penelitian deskriptif analitik dengan pendekatan cross sectional study.Penelitian dilaksanakan di ruangan kelas TK Tunas Bhakti Manado. Sampel dalam penelitian ini seluruh anak prasekolah di TK Tunas Bhakti Manado sebanyak 70 anak diperiksa OHI-S dan kuesioner sebanyak 12 pertanyaan untuk orang tua. Teknik pengambilan sampel dengan metode total sampling. Hasil penelitian ini menunjukkan bahwa pengetahuan orang tua mengenai kebersihan gigi dan mulut dalam kategori baik sebesar 45,7% dengan status kebersihan gigi dan mulut anak termasuk dalam kategori sedang sebesar 65,7%. Berdasarkan hasil uji korelasi pearson didapatkan p value 0,020 (p<0,05). Dapat disimpulkan bahwa terdapat hubungan antara tingkat pengetahuan orang tua dengan kebersihan gigi dan mulut anak di TK Tunas Bhakti Manado. Kata kunci: pengetahuan, OHI-S, anak prasekolah.  


Author(s):  
Mahdieh Momayyezi ◽  
Parisa Peigan ◽  
Hossein Fallahzadeh

Introduction: Understanding the epidemiological pattern and causes of poisoning is the first step to prevent and reduce complications and mortality due to poisoning in children. Given that no study has been conducted on this subject in Yazd, this study aimed to determine the epidemiology pattern of poisoning in children admitted to the referral teaching hospitals in Yazd and Taft cities during 2014-2019. Materials and Methods: This descriptive cross-sectional study was conducted on 238 children under the age of 15 who have been admitted to Shahid Sadoughi hospital in Yazd and Shahid Beheshti hospital in Taft city during 2014-2019. The data were analyzed by SPSS version 20.0 using descriptive statistics, Pearson correlation, and Chi-square. In all the statistical analyses, a P-value of less than 0.05 was considered significant. Results: The results showed that the frequency of poisonings was higher in girls (58%), in summer (31.1%), and in urban areas (82.8%). Most cases of poisoning aged less than 15 years (75.1%). The main cause of poisoning in children was drug poisoning (60.5%), followed by cleansing products (10.1%). The most common clinical manifestations included neurological signs (33.6%). During 2014-2019, the frequency of drugs and pesticide poisonings decreased; while poisoning due to drug-opioids and cleansing products increased (P = 0.04). Also, 3 deaths occurred due to poisoning during this period. Conclusion: The higher prevalence of drug and cleansing products poisoning in children under the age of 15 indicates involuntary poisoning in this group. Therefore, proper storage of these substances and more parental care can reduce poisonings in children.


2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Budi Santoso ◽  
Vivi Buari Putri

AbstractA first menstrual bleeding (is called menarche), as one of the sign of puberty, is veryimportant event in the reproductive life of a woman. Age at menarche is affected by twomajor factors/determinats, genetic and non genetic (environmental), reflects the healthstatus of a population. In recent years, the average age at menarche showed acontinuous trend for earlier, although this trend tends to slow down or stabilize. EarlyAAM may be associated with social and medical problems in later life. This study wasdesigned to determine the relationship of mothers age at menarche and their postmenarchealdaughters at grades 5 and 6 in three Pucangan public elementary schools(SD Negeri I, III, IV Pucangan). Similarity of Elementary School’s location (in thePucangan Village), have a tendency in common areas of residence, socioeconomicstatus, and other non-genetic determinants, so the researchers wanted to know therelationship between menarcheal age of mothers and their daughters.Subject were 31 female students at grades 5 and 6 in SD Negeri, I, III, IV Pucangan,District of Kartasura Sukoharjo. The sampling technique to be used is saturated samplinginwich all of the population to be used as sample.This cross sectional study used Pearson correlation test (with α = 0.05) to analyze dataand obtained p value of 0.402 to p > 0.05 which means that Ho : accepted and Ha :rejected. The result showed that there was no relationship between menarcheal age ofmothers and their daughters at grades 5 and 6 in SD Negeri I, III, IV Pucangan, District ofKartasura Sukoharjo.Keywords : Menarche, Age at Menarche, Genetic Determinants


2021 ◽  
Vol 3 (2) ◽  
pp. 55-63
Author(s):  
Ni Putu Dian Ayu Anggraeni ◽  
Baiq Eka Putri Saudia

Introduction: Physical, social, mental, and psychological issues are common in the first few days after giving birth. According to some research, postpartum depression symptoms are linked to high cortisol levels. Postpartum psychological stress causes higher cortisol levels. Objective: The aim of this study was to look at postpartum mother's anxiety and cortisol levels. Methods: An Analytical Survey with a Cross-Sectional Approach is used in this analysis. With simple random sampling, there were 38 samples that met the inclusion criteria. Data was collected using the PSAS questionnaire for anxiety and an ELISA test for cortisol levels. Univariate and Pearson correlation test is used in the data analysis. Results: The majority of postpartum mothers reported mild anxiety in the first 24 hours after childbirth, with an average cortisol level of 10.034ng/ml 47.4%. The average level of the puerperal hormone cortisol in primiparous women was 14.60ng/ml higher than in multiparous women 7.42 ng/dl. Conclusion: With a p-value of 0.017, there was a substantial difference in cortisol levels between primiparous and multiparous postpartum mothers. With a p-value <0.001, there was a close connection between anxiety scores and cortisol levels. Future studies would need to focus on making it easier for postpartum mothers to feel less anxious.


2019 ◽  
Vol 5 (2) ◽  
pp. 3-7
Author(s):  
Muhammad Ilyas ◽  
Asma Khan ◽  
Syed Murad Ali Shah ◽  
Salman Khan ◽  
Junaid Nadeem Malik

OBJECTIVES: The objective of this study was to determine the correlation of chronological age with the maturation stages of mandibular third molar. METHODOLOGY: This descriptive, cross-sectional study was conducted at Sardar Begum Dental College, Gandhara University Peshawar on 384 patients from January 2018 to June 2018 and included patients having age 11-26 years with good quality Orthopantomogram showing mandibular third molar tooth germs bilaterally. Data were analyzed using SPSS version 22. p ≤ 0.05 was considered as statistically significant. RESULTS: Females 286 (74.5%) were predominant than males 98 (25.5%) with mean age presentation of 18.12±3.03 years. The most frequent stage of Demirjian’s stages of mandibular third molar was stage F (24.7%). Pearson correlation showed that maturation stages of mandibular third molars were significantly related to the chronological age ( r=0.446, p value=0.00). CONCLUSION: A correlation between maturation stages of mandibular third molars and chronological age existed.


2020 ◽  
Vol 9 (1) ◽  
pp. 140-146
Author(s):  
Zakaria Sendy Wardana ◽  
Gadis Meinar Sari ◽  
Damayanti Tinduh

This study used a cross sectional study method using 39 obese women aged 19-22 years old, Body Mass Index (BMI) 25-35 kg / m2 and Percentage Body Fat (PBF) above 30%, normal blood pressure, heart rate normal rest and normal Hemoglobin (Hb). IGF-1 levels were measured using the Enzym Link Immunosorbent Assay (ELISA) method, while the FBG measurements used ACCU-CHEK® Performance. Data analysis techniques used the Pearson Correlation test with the Statistical Package for Social Science (SPSS). The results obtained an average level of IGF-1 (11,530 ± 4,397) ng / mL and an average FBG (90,153 ± 6,659) mg / dL       (r = 0.379) and (p = 0.017). Based on the results of the study, it’s concluded that there is a positive correlation of IGF-1 levels with FBG in obese women. Further research is needed to explain the physiological mechanism of the relation between IGF-1 and FBG in more detail


2019 ◽  
Vol 8 (1) ◽  
pp. 22
Author(s):  
Ratnadewi Ratnadewi

Zinc deficiency is public health problem. Almost two million people in developing country suffered zinc deficiency. Zinc deficiency in Indonesia, 25% in breastfeeding mothers and 17% in babies. The purpose of this study was to determine the correlation of zinc level in breastmilk with 4-6 months old baby weight and length in Padang City West Sumatera. This study was done in working area of Lubuk Buaya, Padang Pasir, and Nanggalo Public Health Center. This study was done from January 2016 until January 2017. The design of this study was cross sectional, number of sample were 108 people. Samples were selected by simple random sampling. Zinc level in breastmilk was checked by AAS (Atomic Absorption Spectrophotometer). Data were analyzed by using univariate and bivariate with pearson correlation test. The correlation test, correlation was positive and patterned between log zinc level in breastmilk with 4-6 months old baby weight (r=0,272), while the length (r=0,216), correlation was positive and weak with p value <0,05. That there were significant correlation between log zinc level in breastmilk and 4-6 months old baby weight and length.


Sign in / Sign up

Export Citation Format

Share Document