scholarly journals The Relation Between IGF-1 Levels and Fasting Blood Glucose in Obese Women

2020 ◽  
Vol 9 (1) ◽  
pp. 140-146
Author(s):  
Zakaria Sendy Wardana ◽  
Gadis Meinar Sari ◽  
Damayanti Tinduh

This study used a cross sectional study method using 39 obese women aged 19-22 years old, Body Mass Index (BMI) 25-35 kg / m2 and Percentage Body Fat (PBF) above 30%, normal blood pressure, heart rate normal rest and normal Hemoglobin (Hb). IGF-1 levels were measured using the Enzym Link Immunosorbent Assay (ELISA) method, while the FBG measurements used ACCU-CHEK® Performance. Data analysis techniques used the Pearson Correlation test with the Statistical Package for Social Science (SPSS). The results obtained an average level of IGF-1 (11,530 ± 4,397) ng / mL and an average FBG (90,153 ± 6,659) mg / dL       (r = 0.379) and (p = 0.017). Based on the results of the study, it’s concluded that there is a positive correlation of IGF-1 levels with FBG in obese women. Further research is needed to explain the physiological mechanism of the relation between IGF-1 and FBG in more detail

2020 ◽  
Vol 9 (2) ◽  
pp. 450-455
Author(s):  
Aryaputra Aryaputra ◽  
Bambang Purwanto ◽  
Achmad Widodo

This study aims to analyze the relationship between hemoglobin concentration and maximal oxygen volume in obese women. This study used a cross sectional study method using 40 obese women aged 18-22 years, body mass index 25-35 kg/m2 and percentage body fat above 30%, normal blood pressure, resting heart normal rate and fasting blood glucose below 100 mg / dL. Measurement of Hb concentration using Easy Touch with a unit concentration of g/dL, while VO2max measurement using the Astrand 6-minute cycle test method. Data analysis techniques used the Pearson Correlation test. The results obtained mean Hb (15,365±1,467) g/dL and VO2max (28,635 ± 4,256) ml/kg /min. Based on the results of the study concluded that there is a positive correlation between Hb levels with maximum oxygen capacity in obese women. Further research is needed to explain the physiological mechanism of the relationship between hemoglobin concentration and maximal oxygen volume in more detail


2020 ◽  
Vol 9 (1) ◽  
pp. 78-84
Author(s):  
Pradika Gita Baskara ◽  
Lilik Herawati ◽  
Purwo Sri Rezeki

This study aims to analyze the correlation between the levels of betatrophin and fasting blood glucose (FBG) in obese females. This study used a cross sectional study method of 26 obese female aged 18-23 years old, body mass index (BMI) 25-35 kg/m2 and body fat percentage (PBF) above 30%. Betatrophin levels were measured by ELISA method, while FBG measurements used ACCU-CHEK® Performance. The data analysis techniques used the Pearson Correlation test with the Statistical Package for Social Sciences (SPSS). The results obtained the average of betatrophin level (165.707 ± 96.124) pg / mL and the average of FBG (90.576 ± 7.094) g / dL (p = 0.021). Based on the results of the study it can be concluded that there is a correlation between levels of betatrophin and FBG in obese adolescent girls with a negative correlation direction


2020 ◽  
Vol 9 (2) ◽  
pp. 1041-1046
Author(s):  
Adek Ardiansyah ◽  
Lilik Herawati ◽  
Damayanti Tinduh

This study aimed to analyze the relationship of insulin-like growth factor 1 with bone mass in obese female. This study used a cross sectional study method using 30 obese women aged 19-23 years, body mass index (BMI) 25-35 kg / m2, normal blood pressure, normal resting heart rate (RHR), normal hemoglobin (Hb). and fasting blood glucose (FBG) <100 mg / dL. Measurement of IGF-1 levels used the Enzym Link Immunosorbent Assay (ELISA) method. Measurement of bone mass using TANITA (Body Composition Analyzer DC3607601 (2) -1604 FA, TANITA Corporation of America, Inc., USA). The data analysis technique used the Pearson product-moment test with Statistical Package for Social Science (SPSS). The results showed that mean levels of IGF-1 (1.17 ± 0.10) ng / mL and bone mass (2.49 ± 0.06) kg (r = 0.712, P ≤ 0.001). Our findings suggest that there was a positive correlation between IGF-1 levels and bone mass


2020 ◽  
Vol 7 (1) ◽  
pp. 27
Author(s):  
Anggun P Yuniaswan ◽  
Santoso Basuki ◽  
Delya Widasmara

Macrophage and Schwann cells are target cell on leprosy disease, where apoptotic is assumed as one of elimination mechanism of macrophage previously infected by M.leprae. Several study showed various result in apoptotic on leprosy disease. Apoptotic level can be evaluated by observing caspase-3 activity, an executioner caspase on cell death. This study is aimed to observe the relationship of caspase-3 expression with paucibacillary and multibacillary types of leprosy. We used observational analytic and cross sectional study with consecutive sampling method. The subject was leprosy patient which had been diagnosed on dermatovenereology division outpatient clinic Saiful Anwar Hospital, and fullfilled the inclusion-exclusion criteria. Total subject was 19 persons (11 multibacillary and 8 paucibacillary). Sampling was taken with punch biopsy on skin lession, followed by immunohistochemical staining with caspase-3 antibody, and caspase-3 expression was measured by ImmunoRatio method. Comparation test revealed significant difference (p<0.05%) between caspase-3 expression mean on paucibacillary patient (84.46%) compared to multibacillary patient (65.39%). Pearson correlation test revealed caspase-3 expression tend to be higher in paucibacillary patient than multibacillary (coefficient correlation -0.759). In conclusion, there is a significance relationship between caspase-3 expression with leprosy type.


2018 ◽  
Vol 3 (1) ◽  
pp. 1 ◽  
Author(s):  
Siti Afina ◽  
Retnaningsih Retnaningsih

<p class="Default"><em>This research was to analyze the influence of students’ knowledge and attitude toward functional foods consumption behavior. This research used cross sectional study design and was conducted at Institut Pertanian Bogor, Dramaga. Samples in this research were 204 students of Institut Pertanian Bogor chosen using simple random sampling method. Data were collected by self-administered technique using questionnaires. The results showed that the average of functional foods consumption frequency was 47 times a month and the number of types consumed was seven. The results of Pearson correlation test showed that students’ allowance, attitudes, and frequency of functional foods consumption was significantly positively correlated. Factors that have significant positive effect toward consumption frequency are allowance and students’ attitude. The number of functional foods types consumed was influenced by students’ attitude. </em></p><p class="Default"><strong> </strong></p>


2018 ◽  
Vol 48 (1) ◽  
pp. 46
Author(s):  
Fifin Pradina Duhitatrissari ◽  
Endang Retnoningsih ◽  
Iriana Maharani

Latar Belakang: Prevalensi rinosinusitis kronik (RSK) jamur saat ini cenderung meningkat. Jamurberperan sebagai mikroorganisme dan merupakan salah satu penyebab RSK. Pemeriksaan immunoglobulinE (IgE) Aspergillus fumigatus (Af) digunakan untuk menegakkan diagnosis rinosinusitis jamur tanpa harusmelalui tindakan invasif. Perubahan rasio neutrofil/eosinofil (RNE) digunakan untuk memahami responinflamasinya. Tujuan: Mengetahui korelasi antara kadar IgE Af terhadap perubahan RNE mukosa dandarah pada penderita RSK jamur. Metode: Penelitian cross sectional, melibatkan 13 subjek penelitiandengan pengambilan darah dan mukosa sinus maksila untuk diidentifikasi Af dengan Polymerase ChainReaction (PCR), dilanjutkan ELISA untuk mengukur kadar IgE Af serta flowcytometry untuk mengukurkadar neutrofil dan eosinofil mukosa sinus maksila dan darah. Hasil: Rerata IgE Af mukosa 1,112±0,883kU/mL, darah 1,041±0,876 kU/mL (N<0,35 kU/L). Dengan uji T berpasangan didapatkan kesesuaian antarakadar IgE Af darah dan mukosa (p=0,852). Rerata eosinofil mukosa 3,9±1,92% (N:0,3-0,7%) dan darah4,88±2,02% (N:3-9%). Rerata neutrofil mukosa 4,28±2,04 (N:1,1-1,7%) dan darah 49,41±13,98% (N:55,8-59,6%). Rerata RNE mukosa 1,77±2,28 (N:2,8). Rerata RNE darah 12,12 ± 6,25 (N:9,6). Didapatkan93,3% mukosa subjek penelitian mengalami inflamasi eosinofilik, 53,3% mengalami inflamasi eosinofilikpada darah. Dengan uji T berpasangan terdapat ketidaksesuaian RNE mukosa dengan darah (p:0,000).Tes korelasi Pearson antara IgE Af dengan RNE mukosa, tidak terdapat korelasi bermakna (p:0,523) danantara IgE Af dengan RNE darah, tidak terdapat korelasi bermakna (p:0,607). Kesimpulan: Terdapatkesesuaian antara kadar IgE Af mukosa dan darah, tetapi tidak terdapat kesesuaian antara RNE mukosadan darah. Tidak terdapat korelasi antara peningkatan kadar IgE Af dengan RNE pada mukosa dan darah.  ABSTRACTBackground: The prevalence of chronic fungal rhinosinusitis (CFR) nowadays tends to increase.Fungi act as microorganisms and is one of the causes of chronic rhinosinusitis. The examination ofimmunoglobulin E (IgE) Aspergillus fumigatus (Af) is applied to establish the diagnosis of CFR withouthaving to do invasive actions. Neutrophil/eosinophil ratio (NER) changes are used to understand theinflammatory response. Purpose: To determine the correlation between IgE Af levels on changes ofmucosal and blood NER in CFR patients. Method: A cross-sectional study, involving 13 subjects bytaking sample of the blood and maxillary sinus mucosa to identify Af with Polymerase Chain Reaction(PCR), followed by ELISA to measure the levels of IgE Af, and flowcytometry to measure the levels ofneutrophils and eosinophils of the blood and mucosa of maxillary sinuses. Results: The mean IgE ofmucosa: 1.112±0.883kU/mL, and of blood: 1.041± 0.876kU/mL (N<0.35kU/L). With paired T-test,there was a match between blood and mucosal IgE level (p=0.852). The mean eosinophil of mucosa:3.9±1.92%,(N:0.3-0.7%) and of blood 4.88±2.02% (N:3-9%). The mean neutrophil of mucosa:4.28±2.04%(N:1.1-1.7%) and of blood 49.41± 13.98%(N:55.8-59.6%). The mean NER of mucosa:1.77±2.28(N:2.8), and of blood: 12.12±6.25(N:9.6). It was revealed that 93.3% of mucosal subjects hadeosinophilic inflammation, 53.3% had eosinophilic inflammation in blood. With paired T-test there wasa mucosal NER mismatch with blood (p:0.000). The Pearson correlation-test between IgE Af and NERmucosa had no significant correlation (p:0.523), and between IgE Af with NER of blood there was no significant correlation (p:0.607). Conclusion: There was a correspondence between IgE Af of mucosaand blood levels, but there was no match between the mucosal and blood NERs. There was no correlationbetween elevated levels of IgE Af and NER in the mucosa and blood.


Author(s):  
Juhi Lohiya ◽  
Vrinda Saxena ◽  
Swapnil Jain ◽  
Vijayta Sharva ◽  
Shweta Chaturvedi ◽  
...  

Background: The representation of dental morbidity and mortality through the implication of Lockers model was scientifically designed. Main focus of the study to assess the oral health related quality of life among one of the most stressful and preoccupied professionals.Methods: Descriptive cross-sectional study was conducted among the 250 lawyers of Bhopal city to integrate oral health with quality of life integrated with oral health component. Morbid condition of dentition was assessed by WHO Dentition status and treatment needs 1997 Performa and its application on Leao and Shiham 5 scale questionnaire comparing it with quality of life. Data was collected; the relationship of DIDL scale was compared with each construct of Locker’s conceptual model on oral health. The collected data was tabulated using excel and analysis was done using SPSS 17.0 version. Pearson correlation test, ANOVA and post hoc were used to test the significance.Results: It was observed that 29.6% of lawyers had impaired quality of life due to morbid condition of dentition and mortality related issues. This shows high dissatisfaction on the part of lawyers related to the oral health. All the dimensions of DIDL scale show statically positive correlation with each other eating restriction and DMFT due to missing component and painful incidences were observed.Conclusions: Dental diseases or problems have definitive effects on individuals’ quality of life with different aspects of their oral health concerns. Such morbid condition has high impact on psychological discomfort.


2021 ◽  
Vol 9 (4) ◽  
pp. 3907-3912
Author(s):  
Subha Pragathi Kanniappan ◽  
◽  
Vishnu Vardhan G.D ◽  

Background: Osteoarthritis (OA) is one of the commonest forms of joint disease, and the knee is one of the most commonly affected joints. OA is clinically associated with pain, joint stiffness, joint deformity and swelling. Kinesiophobia is a condition in which a patient has an excessive, irritational, and debilitating fear of physical movement and activity resulting from a feeling of vulnerability to painful injury or reinjury. This study addresses the influence of biological (eg: X-ray changes) as well as severity of pain, kinesiophobia in individual physical functioning. The purpose of the study aims to know the prevalence of kinesiophobia in patients with OA knee. Methodology: A simple random sampling of 30 patients with diagnosed OA knee who visited Pravara Rural hospital (Loni) was included. The patients included were between the age group of 40 - 80 years and were screened according to inclusion and exclusion criteria. The data collection includes the application of scales (Tampa scale of Kinesiophobia-11) which includes 11 items, WOMAC (3 components), VAS to all the 30 subjects and was taken by the principal investigator. The total scores of each scale were analyzed mean and standard deviation were taken. Pearson correlation test was performed to know the correlation between each component. Result: Pearson correlation test was performed which showed a positive correlation between all the four variables i.e. stage of OA, VAS, TSK 11, WOMAC with r= 0.0312. Conclusion: The present study concluded that as there is progression in level or stage of OA there is increase in severity of pain which leads to further increase in level of kinesiophobia in individuals with OA of knee. This all components furthers leads to decrease in physical functioning in individuals with OA knee. KEY WORDS: Osteoarthritis, knee, Kinesiophobia, TSK11, WOMAC, VAS.


2015 ◽  
Vol 14 (1) ◽  
pp. 19
Author(s):  
Ayub I. Anwar

Dental caries is one of the most frequent tooth decays experienced by pre-school children which can interfere with their growth process. Maintenance instructions for oral health at home have been made byexperts. Theprogramemphasizes theprevention of caries. Parental participation is necessary in guiding, giving understanding, reminding, and providing thefacilities to children so they can maintain the cleanliness of their teeth and mouth. The purpose of this observationalanalytic cross sectional study was to determine the relation of mothers' knowledge of dental and oral health care anddental caries status of students atKusudarsini Kindergarten in Makassar. Research subjects consisted of 33 kindergartenstudents who attended and participated in the study and returned questionnaire study. Pearson correlation test was usedto see the correlation. Correlation between the mother's knowledge and the value of df-t, showed r = -0.263 and p =0.133,which means there is no statistically significant relationship between knowledge of mothers with dental caries status ofchildren. This study concluded that there is no significant relationship between mothers' knowledge of dental and oralhealth with their children’s caries status. The better the mother's knowledge, the lower df-t value.


2021 ◽  
Vol 30 (3) ◽  
pp. 211-4
Author(s):  
Dyandra Parikesit ◽  
Miftah Adityagama ◽  
Widi Atmoko ◽  
Ponco Birowo ◽  
Akmal Taher ◽  
...  

BACKGROUND Aging males’ symptoms (AMS) scale was developed to study the problems of aging males, especially related to the quality of life. Currently, there is no valid and reliable Indonesian version of the AMS scale. This study was aimed to translate and evaluate the validity and reliability of the Indonesian version of the AMS scale. METHODS This cross-sectional study translated the existing AMS scale into Indonesian, which was tested in 40 years old males from May to August 2020. Cross-cultural validation of the AMS scale was conducted by translating the questionnaire from English to Indonesian by two independent-certified translators. The validity of the Indonesian version of the AMS scale was measured by conducting a Pearson correlation (r) analysis. The reliability of this questionnaire was tested and retested in 118 participants with a 2-week interval. In addition, Cronbach’s alpha value was measured and used as a reference. The first test was conducted in a corporate blood donor event in Matraman, East Jakarta, and the retest was conducted in Cipto Mangunkusumo Hospital. RESULTS The Indonesian version of the AMS scale was valid and had a good internal consistency with a Cronbach’s alpha value of 0.74. The test-retest reliability showed good reliability with an r-value of 0.981. Pearson correlation test showed that all questions in the questionnaire were valid (p<0.05) and correlated positively. CONCLUSIONS The Indonesian version of the AMS scale derived from this study is valid and has good reliability.


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