scholarly journals Fuzzy logical conclusions and conclusions in expert systems of medical diagnostics

Author(s):  
Yuriy Zack

The main problems in making a correct diagnosis are: subjectivity and insufficient qualifications of the doctor, difficulties in correctly assessing the patient’s complaints, signs and symptoms of the disease observed in the patient, as well as individual manifestations of the symptoms of the disease. In publications on the use of expert systems for medical diagnostics using fuzzy logic, the main attention was paid to the medical features of the problem. In this work, for the first time, general methodological aspects of building such systems, creating databases, representing by fuzzy sets of real numbers, digital scales, linguistic and Boolean data of symptom values are formulated. The types of membership functions that are advisable to use to represent the symptoms of diseases are proposed. In fuzzy-logical conclusions, not only the values of the characteristic functions of the logical terms of individual symptoms, but also complex arithmetic functions of their values are used.

2016 ◽  
Vol 5 (08) ◽  
pp. 4744
Author(s):  
Zahra Ibrahim El-Gali

This study was carried out to identify the unknown different symptoms and their causes as plant pathogenic fungi from Al-Jabal Al-Akhdar District. Plant materials with fungal signs and symptoms were collected and examined. The main fungi consistently isolated from symptomatic leaves and twigs were Pestalotiopsis spp. Morphology, colony characteristics, and pathogenicity of the isolates were examined. My report the occurrence of Pestalotiopsis spp. on leaves of mastic (Pistacia lentiscus) for the first time in Libya.


2021 ◽  
Vol 51 (1) ◽  
pp. 10-15
Author(s):  
Kenneth V Iserson ◽  
Sri Devi Jagjit ◽  
Balram Doodnauth

Acute thoracic aortic dissection is an uncommon, although not rare, life-threatening condition. With protean signs and symptoms that often suggest more common cardiac or pulmonary conditions, it can be difficult to diagnose. Ultrasound has proven useful in making the correct diagnosis. This case demonstrates that training gained using standard ultrasound machines can be easily and successfully adapted to newer handheld ultrasound devices. The examination technique using the handheld device is illustrated with photos and a video.


Author(s):  
Ellahe Azizlou ◽  
Mohsen AminSobhani ◽  
Sholeh Ghabraei ◽  
Mehrfam Khoshkhounejad ◽  
Abdollah Ghorbanzadeh ◽  
...  

Extraoral sinus tracts of odontogenic origin often develop as the result of misdiagnosis of persistent dental infections due to trauma, caries, or periodontal disease. Due to these lesions' imitation from cutaneous lesions, misdiagnosis, and mismanagement, which we frequently encounter, this article aims to describe four cases with manifestations in different parts of the face and the neck. Patients were referred to an endodontist with a history of several surgical procedures and/or antibiotic therapy due to misdiagnosis. After comprehensive examinations, root canal treatment was performed. The resolution of signs and symptoms during the follow-up period confirmed the correct diagnosis. Dermatologists and other physicians should be aware of the possibility of the relationship of extraoral sinus tracts with dental infections. Precise examination and taking a comprehensive history can aid to prevent unnecessary and incorrect therapeutic and/or pharmaceutical interventions. Elimination of dental infection leads to complete recovery in such patients.


Fuzzy Systems ◽  
2017 ◽  
pp. 935-968
Author(s):  
A. B. Bhattacharya ◽  
Arkajit Bhattacharya

This chapter presents the importance of fuzzy expert systems in the medical field. Efficient and suitable medical work becomes difficult many times without the knowledge of the rules of logic. The chapter highlights the ways of implementing both classical logic and non-classical approach (e.g. temporal and fuzzy logic) in some adverse areas of medical diagnostics. The implementation of fuzzy expert systems is supported by some examples illustrating how indispensable the cognition of logic and showing how applying logic can effectively improve work in medicine. Fuzzy Expert Systems for diagnosis of urinary incontinence, Parkinson's disease, including neurological signs in domestic animals, as well as its implementation for diagnosis of prostate cancer are elaborately discussed.


Author(s):  
E Spinelli ◽  
G Blevins ◽  
J Mailo ◽  
L Atilano ◽  
H Leonard ◽  
...  

Background: Sarcoidosis is a multiorgan autoimmune disease characterized by the presence of non-caseating granulomas. The diagnosis can be difficult, particularly with central nervous system (CNS) involvement, and pathology outside of the CNS has to be carefully evaluated. Early and correct diagnosis is crucial for appropriate management particularly in children where sarcoidosis and neurosarcoidosis are rare. Methods: We describe a 16 year old previously healthy boy who presented with progressive pyramidal neurological signs and symptoms localizable primarily to the brain stem. Results: Initial imaging revealed striking brainstem, as well as cerebral, cerebellar and spinal cord perivascular enhancement. Lung involvement was subclinical with a miliary pattern on chest imaging and needle biopsy revealed an interstitial lymphocytic infiltration. Extensive serum and CSF rheumatological, autoimmune and infectious investigations were noncontributory. Serum ACE levels were at first within normal limits. Steroid treatment stabilized symptoms and perhaps coincidentally, separate rituximab treatments were followed within days by vertigo (with a new pontine lesion) or a respiratory decompensation. A wedge lung biopsy revealed granulomatosis. Current treatment consists of mycophenolate, methotrexate with a prednisone wean. Conclusions: This case report reinforces the varied manifestations and mimics of sarcoidosis (including CLIPPERS) and highlights the need for a high index of suspicion despite apparently negative investigations.


2007 ◽  
Vol 73 (1) ◽  
pp. 58-61 ◽  
Author(s):  
Dorna Rezania ◽  
Abderrhman Ouban ◽  
Jorge Marcet ◽  
Scott Kelley ◽  
Domenico Coppola

The association between cytomegalovirus infection and inflammatory bowel disease challenges both the clinician and the pathologist to establish the correct diagnosis and to prescribe the most appropriate form of therapy. To understand this association the authors report three patients who presented with signs and symptoms mimicking reactivated inflammatory bowel disease who responded poorly to aggressive treatment of inflammatory bowel disease. Microscopic examination, in all three cases revealed numerous nuclear and cytoplasmic viral inclusions, as demonstrated by cytomegalovirus immunohistochemistry, as well as histologic findings consistent with inflammatory bowel disease (ulcerative colitis and/or Crohn's disease). Because the clinical pathologic features of cytomegalovirus colitis and inflammatory bowel disease often overlap, and because of the possible coexistence of cytomegalovirus colitis with idiopathic colitis, the possibility of cytomegalovirus infection should be always considered, so that the most appropriate therapy can be instituted for these patients.


2019 ◽  
Vol 20 (4) ◽  
pp. 244-246
Author(s):  
Ko-Hsuan Chen ◽  
Ann Blount ◽  
Brittany Justesen ◽  
Joseph H. Walter ◽  
Marcelo Wallau ◽  
...  

Myriogenospora atramentosa is an epibiont fungus that produces black, linear stromata on the leaves of warm-season grasses including Paspalum and Andropogon. Because M. atramentosa is in the family Clavicipitaceae containing several ergot alkaloid-producing fungi, its mycotoxin production and the potential risk to cattle health are of concern. Limpograss (Hemarthria altissima) is a warm-season perennial grass that plays a key role in the cattle industry of the southeastern United States. Limpograss plants with tangletop signs and symptoms were collected in October 2018 from Osceola County, Florida, U.S.A. M. atramentosa was confirmed. M. atramentosa is reported to be associated with the plant genus Hemarthria for the first time, through morphological and molecular investigations. Because of the increasing human usage, animal consumption, and global distribution of H. altissima, understanding its codistribution with M. atramentosa and the potential mycotoxin content is critical to protect plants and animals.


Blood ◽  
2006 ◽  
Vol 108 (8) ◽  
pp. 2520-2530 ◽  
Author(s):  
Giampaolo Merlini ◽  
Marvin J. Stone

AbstractThe detection of a monoclonal immunoglobulin in serum or urine usually raises concerns about the size of the underlying B-cell-derived clone and possible systemic effects caused by its expansion. However, a small clone can synthesize a very toxic protein, producing devastating systemic damage and protean clinical presentations. The resulting “monoclonal component-related diseases,” although difficult to diagnose, may be progressive and even fatal. The monoclonal protein can aggregate and deposit systemically as occurs in light-chain amyloidosis, monoclonal immunoglobulin deposition disease, crystal-storing histiocytosis, and monoclonal cryoglobulinemia. Alternatively, some monoclonal proteins possess antibody activity toward autogenous antigens and cause chronic cold agglutinin disease, mixed cryoglobulinemia, and peripheral neuropathies. Other humoral mediators may contribute to neuropathy in variant disorders such as the POEMS (polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes) syndrome. The clone synthesizing the noxious monoclonal proteins is often small, and sensitive techniques may be required to detect these immunoglobulins. A delay in diagnosis can allow irreversible organ damage and dramatically shorten survival. Prompt recognition of suggestive signs and symptoms should trigger a thorough diagnostic approach to reach the correct diagnosis quickly, because this is the key to effective therapy. Although the treatment of these conditions is not optimal, significant advances have been made, improving the duration and quality of life.


1983 ◽  
Vol 59 (4) ◽  
pp. 660-663 ◽  
Author(s):  
Abelardo Salazar ◽  
Julio Sotelo ◽  
Hector Martinez ◽  
Francisco Escobedo

✓ The fourth ventricle is frequently affected in patients with cysticercosis of the central nervous system, due either to a large cyst occluding the cavity or to granular ependymitis (ventriculitis) as a consequence of diffuse inflammation within the intraventricular and subarachnoid spaces. In some cases, the differential diagnosis between these two forms of neurocysticercosis is difficult to make, even after special radiological procedures. It is important to establish the correct diagnosis, since a surgical approach is beneficial only when the fourth ventricle is obstructed by a large cyst. In this paper, the clinical differences between fourth ventricle cysts and ventriculitis are presented in 16 patients with neurocysticercosis who were subjected to surgical exploration of the posterior fossa. Patients with a large cyst occluding the fourth ventricle had a short evolution of signs and symptoms, Bruns' syndrome, and discrete or no inflammatory reaction in the cerebrospinal fluid (CSF). Patients with ventriculitis generally had a longer duration of signs and symptoms, Parinaud's syndrome, a consistently positive complement fixation test to cysticerci, and more cells and proteins in the CSF. The clinical picture and ancillary studies can give the precise diagnosis in most patients before surgical exploration is performed.


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