scholarly journals Effect of Black Soybean (Glycine max (L.) Merrill) Flour Intervention on Blood Pressure, Fasting Blood Glucose Level and Lipid Profile of Hypertensive Postmenopausal Women

Author(s):  
Neetu Dobhal ◽  
Rita Singh Raghuvanshi
2019 ◽  
Vol 7 (2) ◽  
pp. 107-114
Author(s):  
Shafira Tri Handayani ◽  
Yuwono Setiadi ◽  
Yuniarti Yuniarti

Background : Obesity in adolescence associated with the incidence of metabolic syndrome. The metabolic syndrome is a group of metabolic disorders characterized by high blood pressure, high fasting blood glucose, high triglycerides, low HDL and central obesity. An increasing number of metabolic syndrome in line with the increase in the number of obesity. Based on RISKESDAS 2013 increased the proportion of central obesity from 2007 to 2013 by 18.8% to 26.6%. The prevalence of central obesity in Semarang 21.5%.Aim : Knowing the relationship among intake with waist circumference, fasting blood glucose level and blood pressure in obese adolescents in SMAN 9 Semarang.Method : This study was an observational study with cross-sectional design. Sampling was conducted randomized to receive 47 samples. The data collected is macro nutrients intake factors with 24 hours recall method, weight, height, waist circumference, fasting blood glucose level and blood pressure. Data was collected by the method of anthropometry; interviews, blood pressure measurement and fasting blood glucose level measurement. The correlations test using linear regression.Results: There is a correlation between intake with waist circumference (p 0.046 0.05) with a moderate relationship (R = 0.454) and contributed 20.6%, there is a correlation between intake with fasting blood glucose level (0.039 p 0.05) with the level of relationship is (R = 0.448) and contributed 20.1%, there is a correlation between intake with systolic blood pressure (p 0.004 0.05) with a strong correlation (R = 0.556) and contributed 30.6%, and there is no correlation between intake factor with diastolic blood pressure (p 0.113 0.05) and contributed 16.3%.Conclusion: There is a correlation among intake with waist circumference, fasting blood glucose level and systolic blood pressure. There is no correlation between intake with diastolic blood pressure.


2018 ◽  
Vol 3 (6) ◽  
pp. e001002 ◽  
Author(s):  
Stephanie A Kujawski ◽  
Hannah H Leslie ◽  
Dorairaj Prabhakaran ◽  
Kavita Singh ◽  
Margaret E Kruk

IntroductionIn India, for most patients, primary healthcare remains the intended entry point for the management of non-communicable disease risk factors. The extent and determinants of non-utilisation of public primary care among households with hypertension are not well examined. We explored health facility utilisation patterns and reasons for non-utilisation of public facilities in 21 states and union territories in India, with a focus on hypertension.MethodsWe used data from the 2012–2013 District Level Household and Facility Survey. We examined the self-reported usual source of care for all households, households with hypertension and─to understand multimorbidity for those with hypertension─households with hypertension and diabetes. Hypertension was defined by self-reported diagnosis or measurement of systolic blood pressure ≥140 mm Hg or diastolic blood pressure ≥90 mm Hg. Diabetes was defined by self-reported diagnosis or fasting blood glucose level ≥ 7.0 mmol/L or non-fasting blood glucose level ≥ 11.1 mmol/L. We assessed facility utilisation choice and reasons for non-utilisation of public facilities by household with the presence of hypertension alone and hypertension with diabetes.ResultsIn 336 305 households, 37.6% (N=126 597) had at least one household member with hypertension, while 15.9% (N=53 385) had members with hypertension and diabetes. 20.0% of households sought care at public primary clinics, 29.9% at public hospitals and 48.3% at private facilities. Choice of private facilities increased with the burden of disease. Households with hypertension only and hypertension and diabetes cited quality reasons for non-utilisation of public facilities more than households without hypertension.ConclusionHouseholds, particularly those with hypertension, chose private over public primary facilities for usual care. Quality of care was an important determinant of facility choice in households with hypertension and diabetes. With the increase in hypertension and cardiovascular disease in India, quality of public primary healthcare must be addressed for current policy to become reality.


2021 ◽  
Author(s):  
Yordanos Berihun Yohannes ◽  
Berhanu Teshome Woldeamanuel ◽  
Buzuneh Ayano

Abstract Background: Diabetes describes a group of metabolic disorders characterized and identified by hyperglycemia without treatment. It includes defects in insulin secretion, insulin action, or both, and disturbances of carbohydrate, fat, and protein metabolism. The study aimed to assess fasting blood glucose level progression and its associated factors among diabetic patients attending insulin and metformin follow-up in fiche and Chancho hospitals.Methods: A retrospective study was conducted to obtain secondary data among diabetic patients attending treatment from September 2016 to August 2018 in the hospital. The linear- mixed effects model for longitudinal data was employed to measure the changes in fasting blood glucose level.Result: The result of the study revealed that age, body mass index, systolic blood pressure, diastolic blood pressure, marital status, regime, and education level were significantly associated factors for the progression of fasting blood glucose levels among diabetic patients. Conclusion: The study recommended that the progression of blood glucose level was higher among diabetic patients, and the health professionals, health sectors, and government should be paid an intervention on patients who had high systolic and diastolic blood pressure, who had high BMI, and older age patients.


2020 ◽  
Author(s):  
Mahalul Azam ◽  
Fetty Nur Hidayati ◽  
Arulita Ika Fibriana ◽  
Udin Bahrudin ◽  
Syed Mohamed Aljunid

AbstractThe present study aimed to explore the prevalence of isolated systolic hypertension (ISH) and its risk factors among diabetes mellitus (DM) subjects in the community setting study in Indonesia. This cross-sectional study extracted secondary data from basic health survey (Riset Kesehatan Dasar; RISKESDAS) conducted in 2018. DM subjects were defined based on fasting blood glucose level ≥ 126 mg/dL or 2 hours postprandial and random blood glucose level ≥ 200 mg/dL or previously had been diagnosed by a doctor; while ISH was determined based on systolic blood pressure ≥ 140 mmHg and diastolic blood pressure < 90 mmHg. We also observed the subject’s characteristics, such as demography, lipid profile, and subject’s compliance. Data were then analyzed using Chi-square and Binary logistic regression. Study involved 3,911 DM subjects, revealed the overall prevalence of ISH 17.5%. Age category of 35-44 years old (POR= 10.80; 95%CI: 2.595-44.957), 45-54 years old (POR=22.81; 95%CI: 5.616-92.677), 55-64 years old (POR=46.12; 95% CI: 11.393-186.720); 65-74 years old (POR= 81.82; 95% CI: 20.110-332.868); ≥75 years old (POR=109.64; 95% CI: 26.373-455.789), low HDL cholesterol (POR= 0,80; 95% CI: 0.653-0.972); duration of DM (POR= 1.73; 95% CI: 1.257-2.389) were associated with the ISH. The prevalence of ISH among DM subjects was 17.5%. Older DM subjects, low HDL cholesterol, and duration of DM were associated with the ISH, suggesting that modification lipid profile, especially the HDL cholesterol level, is an important measure to delay ISH in elderly and long-duration DM subjects.


Author(s):  
Shibu Narayan Jana ◽  
Papiya Mitra Mazumder

Objective: The present study was aimed at the development of partial pancreatectomy in a murine model for diabetes.Methods: Diabetes model was successfully developed by partial pancreatectomy method. In this study, cyclosporine was used for influenced the glycaemic status. Diabetes status was evaluated by fasting blood glucose level (FBG), lipid profile (by estimation of total cholesterol level and HDL-level), serum amylase and biochemical assay like glutathione estimation.Results: We report here the restoration of euglycaemic status in cyclosporine-induced diabetic in swiss albino mice after 30% pancreatectomy. In this study, Pancreatectomised (partial) group of animals showed a rapid elevation of glycaemic status, starting from 15th post observational d, but the level of significance decreased gradually from 15th (P<0.01) to 60th (P<0.05) d. This was probably due to nesidioblastotic activity which shifted the fasting blood glucose level towards normoglycaemic status with β-cells regeneration. Cyclosporine treated a group of mice showed normoglycaemic status throughout the whole experimental period, but the cholesterol level remained significant (P<0.001) till the end of the experimental d. Gradually decrements in glycaemia of the diabetic pancreatectomised animals demonstrate islets neogenesis occurring after the operative activity, leading to normoglycaemic condition, probably attributed to β-cells proliferation.Conclusion: The biochemical and histopathological evaluations suggest that there is the development of the diabetic model in the pancreatectomized group and diabetes status induced by pancreatectomy is curable to a certain extent due to the regeneration of β-cells.


2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Kimimasa Sasaki ◽  
Shin Kobayashi ◽  
Masashi Kudo ◽  
Motokazu Sugimoto ◽  
Shinichiro Takahashi ◽  
...  

Abstract Background Immune checkpoint inhibitors (ICIs) are emerging agents used for the treatment of various malignant tumors. As ICIs are generally used for unresectable malignant tumors, there have been only a few reports of patients who underwent surgery after receiving these drugs. Therefore, it remains unclear how immune-related adverse events (irAEs) affect the postoperative course. Here, we report a patient with advanced gastric cancer who underwent laparoscopic hepatectomy for liver metastases after an objective response with lenvatinib plus pembrolizumab and developed hypothyroidism and hypopituitarism as irAEs in the immediate postoperative period. Case presentation A 73-year-old man had undergone total gastrectomy for pT4aN2M0 gastric cancer followed by adjuvant chemotherapy with S-1 and docetaxel, and developed liver metastases in segments 6 and 7. He was enrolled in phase 2 clinical trial of lenvatinib plus pembrolizumab. He continuously achieved a partial response with the study treatment, and the liver metastases were decreased in size on imaging. The tumors were judged to be resectable and the patient underwent laparoscopic partial hepatectomy for segments 6 and 7. From the 1st postoperative day, the patient continuously presented with fever and general fatigue, and his fasting blood glucose level remained slightly lower than that before the surgery. On the 4th postoperative day, laboratory examination revealed hypothyroidism and hypopituitarism, which were suspected to be irAE caused by lenvatinib plus pembrolizumab after surgery. He received hydrocortisone first, followed by levothyroxine after adrenal insufficiency was recovered. Subsequently, his fever, general fatigue, and any abnormality regarding fasting blood glucose level resolved, and he was discharged on the 12th postoperative day. After discharge, his laboratory data for thyroid and pituitary function remained stable while receiving hydrocortisone and levothyroxine without recurrence of gastric cancer. Conclusion We present a case of laparoscopic hepatectomy after receiving lenvatinib plus pembrolizumab and developed hypothyroidism and hypopituitarism after surgery. Regarding surgery after ICI therapy, it is important to recognize that irAEs might occur in the postoperative period.


Sign in / Sign up

Export Citation Format

Share Document