scholarly journals A Study on Bacterial Etiology of Cholecystitis due to Gallstones and their Antimicrobial Susceptibility Pattern in A Tertiary Care Hospital

Author(s):  
B. Gomathi Manju N. Rathna Priya ◽  
G. Jayalakshmi

Cholelithiasis is a very common condition affecting the Gallbladder. Gallstones are present in 10 -15 % of the adult population. Females are three times more likely to develop Gallstones than male. Gall stones are classified into cholesterol and pigment stone. About 80% of them are cholesterol stone and 15-20% pigment stone. Obstruction and infections are the common complications of Cholelithiasis. Approximately 1-2% of the patients become symptomatic and warrants cholecystectomy (1). With this background we conducted a cross sectional study in the Institute of Microbiology, MMC & RGGGH, for 72 consecutive patients who underwent cholecystectomy. The most common age group affected 41-60 yrs. The most common symptoms are abdominal pain, dyspepsia and Jaundice. In this study Gallstones are collected after surgery, processed and Antibiogram pattern also studied as per standard guidelines. Out of 72 samples studied 35 (48.6%) are culture positive. Escherichia coli is the predominant organism isolated followed by Klebsiella pneumonia(52). Most of the isolates were sensitive to commonly used antibiotics for Gram Negative bacilli.

Author(s):  
Priyanka Pradhan Sneha Mohan ◽  
Tarana Sarwat Dalip Kakru

Methicillin resistant Staphylococcus aureus (MRSA) is major cause of nosocomial and community infections. Its prevalence varies with country and with hospitals within a country. Therefore, it is important for continuous surveillance in hospitals and other healthcare facilities in order to limit the spread of infections caused by MRSA. To determine the antibiogram of Staphylococcus aureus in a tertiary care hospital and to determine the change in trends in the antimicrobial susceptibility pattern of Staphylococcus aureus. To determine the prevalence of MRSA in a tertiary care hospital. This cross- sectional study was conducted at the Department of Microbiology, SMSR, Sharda University and Hospital. A total of 100 strains identified by morphological and biochemical characteristics were tested for antibiotic susceptibility using Kirby-Bauer disc diffusion method and the Prevalence of Inducible Clindamycin Resistance among the isolates. 100 out of 13,639 isolates clinical comprising samples were obtained Pus (78.6%), Blood (7%), Swab (4.1%), Sputum (4.1%), Urine (4.1%), Semen (2%). Maximum MRSA were obtained from pus samples (81%). However, out of total 7 isolates of Staphylococcus aureus obtained from blood 4 were MRSA and 3 were MSSA. The prevalence of MRSA that is (40%) infections was a high in our setup and is comparable to studies done earlier. This trend is particularly alarming for Staphylococcus aureus because of the severity and diversity of disease caused by this uniquely versatile pathogen.


Author(s):  
Praveen Gowda ◽  
Subhashini K. J. ◽  
Siddharam S. Metri ◽  
M. Sundar

Background: Animal bites cause a big burden in terms of morbidity and mortality throughout the world. These bites could be caused by rabid animals causing rabies. Annually about 59,000 persons die of rabies, of which 20,000 is from India alone. Rabies though 100% fatal is preventable with post-exposure prophylaxis which includes wound wash, anti-rabies vaccination (ARV) and rabies immunoglobulin. The objectives of the present study was to describe the demographic profile of animal bite cases and to assess the management practices of animal bite cases reporting to dedicated anti-rabies clinic (ARC) of a tertiary care hospital, Hassan, Karnataka.Methods: A cross-sectional study was conducted from the inception of anti-rabies clinic (12th October 2017) to August 2018 among animal bite cases reported to ARC. They were interviewed by using a semi-structured, pre-designed and pre-tested proforma. Data regarding socio-demographic profile were collected from the animal bite victims. All the animal bite cases were managed as per WHO guidelines.Results: The total number of animal bite victims reported to ARC during the study period was 3500. Majority of the bite victims belonged to adult population (20-60 years). Majority were males (66.2%). 77% belonged to the rural population. Dogs (97.1%) were the most common biting animal. 79% of the bites were provoked. Turmeric powder was the most commonly used irritant. Most bites belonged to Category III (84%). Category I, II, III bites were managed appropriately according to WHO guidelines.Conclusions: Knowing the burden, socio-demographic characteristics and the management of animal bite victims in the dedicated ARC of HIMS has helped the programme officer in implementing the National Rabies Control Programme in Hassan district.


Author(s):  
Bershic Valantine ◽  
R. Prahan Kumar ◽  
Senthilvel Vasudevan ◽  
Jayanthi Sureshbabu ◽  
Zile Singh

Background: Dengue is one of the world’s emerging and rapidly spreading pandemic disease of public health importance.  High rainfall and low temperatures are associated with increased number of dengue cases.Methods: A hospital based cross sectional study was conducted between 15th August 2013 and 15th October 2013 with a sample of 200 in a tertiary care multi-speciality hospital in Puducherry using pre-designed and pre-tested questionnaire. The study protocol was approved by ICMR and Institutional (PIMS) Ethical Committee.  Participants were included in the study based on the following criteria: (1) More than 20 years of age. (2) Permanent resident of Pondicherry.Results: Out of the 200 participants 68% were males and 32% were females. Most of them (64%) had gone to schools, while 9.5% were illiterates. Of the 200 participants, 180 (90%) knew that mosquito is the vector for Dengue. 162 (81%) of participants felt hospitalisation is necessary for dengue management. 80% of participants mentioned use of ceiling fan as a predominantly used preventive measure against mosquito bite, whereas 43% of them use mosquito coils to avoid mosquito bites. Majority of the respondents (66%) spend less than Rs.100 ($ 1.47) in a month for various mosquito preventive measures.Conclusions: The knowledge about dengue was good, although more awareness needs to be created to identify the clinical signs of dengue. The overall attitude and practices of the participants towards dengue care, prevention and control is good. 


Author(s):  
Rakesh K. Nayak ◽  
Raghavendra D. Kulkarni ◽  
Ganavalli S. Ajantha

Background: The prevalence of HIV among the adult population has continued a steady decline at the national level from an estimated peak of 0.4% in 2000 down to 0.26% in 2015. The data generated by ICTC may provide important clues to understand the epidemiology of the disease in a specific area, as well as pattern of risk behavior of the population.Methods: The present retrospective record based cross sectional study was carried out at the ICTC Centre of SDM College of Medical Sciences and Hospital, Dharwad. Retrospective data for the past six years (2012-13 to 2017-18) on clients visiting the ICTC was collected from the ICTC registers.Results: A total of 45,066 clients attended the ICTC over a period of 6 years, among which 61.6% were females and 38.4% were males. Among the total females, 55% were antenatal mothers. Out of the total clients tested, 99.75% of clients underwent post-test counseling. Among the total clients, 669 were HIV sero-positive clients out of which majority (61.7%) were males. The total positivity rate was 1.48% among the ICTC attendees. 47 clients had co-infections with TB.Conclusions: The challenge is to increase access to and uptake of HIV testing priority. Intense IEC activities for behaviour change at grass root level populations should be encouraged. 


Vacunas ◽  
2020 ◽  
Vol 21 (2) ◽  
pp. 95-104 ◽  
Author(s):  
Y.M. AlGoraini ◽  
N.N. AlDujayn ◽  
M.A. AlRasheed ◽  
Y.E. Bashawri ◽  
S.S. Alsubaie ◽  
...  

Author(s):  
Nandini Chatterjee ◽  
Supratick Chakraborty ◽  
Mainak Mukhopadhyay ◽  
Sinjon Ghosh ◽  
Bikramjit Barkandaj ◽  
...  

2020 ◽  
Vol 32 (1) ◽  
Author(s):  
Nearmeen M. Rashad ◽  
Marwa G. Amer ◽  
Waleed M. Reda Ashour ◽  
Hassan M. Hassanin

Abstract Background Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system with varied clinical features. Disease-modifying drugs (DMDs) of MS associated with different types of thyroiditis. In this cross-sectional study, we aimed to assess the prevalence of thyroid dysfunction in MS and to investigate the association between DMDs and the risk of thyroiditis in MS. A cross-sectional study included 100 patients with relapsing-remitting multiple sclerosis (RRMS) in relapse, and the diagnosed was according to revised McDonald’s criteria 2010. Results Our results revealed that the prevalence of thyroiditis was 40%; autoimmune (34%) and infective (6%) among patients with RRMS in relapse and cerebellar symptoms were significantly higher in patients with thyroiditis compared to patients without thyroiditis. Regarding the association between DMDs and thyroiditis, the prevalence of patients treated with interferon-beta-1b was higher in MS patients with thyroiditis compared to MS patients without thyroiditis. However, the prevalence of patients treated with interferon-beta-1a was lower in MS patients with thyroiditis compared to MS patients without thyroiditis. In addition, we found CMV infection was more common in patients treated by interferon beta-1b and candida infection was common in patients treated by fingolimod. Conclusions Thyroiditis is commonly observed in patients with RRMS in relapse and higher prevalence of patients treated with interferon-beta-1b which is commonly associated with thyroiditis and CMV infection; however, candida thyroid infection was common in MS patients treated by fingolimod.


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