scholarly journals Revisiting Temperaments with a Fine-Tuned Categorization Using Iranian Traditional Medicine General Ontology

Author(s):  
Ayeh Naghizadeh ◽  
Donya Hamzeheian ◽  
Shaghayegh Akbari ◽  
Hossein Rezaeizadeh ◽  
Mahdi Alizadeh Vaghasloo ◽  
...  

Background: Iranian traditional medicine is a holistic school of medicine with a long prolific history. It describes numerous concepts and the relationships between them. However, no unified terminology has been proposed for the concepts of this medicine up to the present time. Considering the extensive use of concepts in the numerous textbooks written by the scholars over centuries, comprehending the totality of the terminology is obviously a very challenging task. To resolve this issue and overcome the obstacles, and code the concepts in a reusable manner, constructing an ontology of the concepts of Iranian traditional medicine seems a necessity.Methods: Makhzan al-Advieh, an encyclopedia of materia medica compiled by Mohammad Hossein Aghili Khorasani, was selected as the resource to create an ontology of Mizaj. The steps followed to accomplish this task included (1) compiling the list of classes for Mizaj; (2) arranging the classes in taxonomy; (3) determining object properties and their cardinalities; (4) specifying annotation properties including codes, labels, synonyms, and definitions for each concept; (5) reviewing the fields pertaining to Mizaj of all monographs in Makhzan al-Advieh. The ontology was created using Protégé with adherence to the principles of ontology development provided by the Open Biological and Biomedical Ontology (OBO) foundry. Results: Mizaj ontology was constructed with a final inclusion of 105 classes, three object properties, and 1078 axioms in the Iranian Traditional Medicine General Ontology database, IrGO, freely available at http://jafarilab.com/irgo/. An indented tree view and an interactive graph view using WebVOWL were used to visualize the ontology. All classes were linked to their instances in the UNaProd database to create a knowledge-base of Mizaj. Conclusion: We constructed an ontology-based knowledge base of ITM concepts of Mizaj in the domain of materia medica to help offer a shared and common understanding of this concept, enable reuse of the knowledge, and make the assumptions explicit. Extending IrGO will bridge the gap between traditional and conventional schools of medicine and help guide future research on new treatment options.

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Ayeh Naghizadeh ◽  
Mahdi Salamat ◽  
Donya Hamzeian ◽  
Shaghayegh Akbari ◽  
Hossein Rezaeizadeh ◽  
...  

Abstract Background Iranian traditional medicine, also known as Persian Medicine, is a holistic school of medicine with a long prolific history. It describes numerous concepts and the relationships between them. However, no unified language system has been proposed for the concepts of this medicine up to the present time. Considering the extensive terminology in the numerous textbooks written by the scholars over centuries, comprehending the totality of concepts is obviously a very challenging task. To resolve this issue, overcome the obstacles, and code the concepts in a reusable manner, constructing an ontology of the concepts of Iranian traditional medicine seems a necessity. Construction and content Makhzan al-Advieh, an encyclopedia of materia medica compiled by Mohammad Hossein Aghili Khorasani, was selected as the resource to create an ontology of the concepts used to describe medicinal substances. The steps followed to accomplish this task included (1) compiling the list of classes via examination of textbooks, and text mining the resource followed by manual review to ensure comprehensiveness of extracted terms; (2) arranging the classes in a taxonomy; (3) determining object and data properties; (4) specifying annotation properties including ID, labels (English and Persian), alternative terms, and definitions (English and Persian); (5) ontology evaluation. The ontology was created using Protégé with adherence to the principles of ontology development provided by the Open Biological and Biomedical Ontology (OBO) foundry. Utility and discussion The ontology was finalized with inclusion of 3521 classes, 15 properties, and 20,903 axioms in the Iranian traditional medicine General Ontology (IrGO) database, freely available at http://ir-go.net/. An indented list and an interactive graph view using WebVOWL were used to visualize the ontology. All classes were linked to their instances in UNaProd database to create a knowledge base of ITM materia medica. Conclusion We constructed an ontology-based knowledge base of ITM concepts in the domain of materia medica to help offer a shared and common understanding of this concept, enable reuse of the knowledge, and make the assumptions explicit. This ontology will aid Persian medicine practitioners in clinical decision-making to select drugs. Extending IrGO will bridge the gap between traditional and conventional schools of medicine, helping guide future research in the process of drug discovery.


2020 ◽  
Vol 2020 ◽  
pp. 1-14
Author(s):  
Ayeh Naghizadeh ◽  
Donya Hamzeheian ◽  
Shaghayegh Akbari ◽  
Fahimeh Mohammadi ◽  
Tohid Otoufat ◽  
...  

Background. Iranian traditional medicine (ITM) is a holistic medical system that uses a wide range of medicinal substances to treat disease. Reorganization and standardization of the data on ITM concepts is a necessity for optimal use of this rich source. In an initial step towards this goal, we created a database of ITM materia medica. Main Body. Primarily based on Makhzan al-Advieh, which is the most recent encyclopedia of materia medica in ITM with the largest number of monographs, a database of natural medicinal substances was created using both text mining methods and manual editing. UNaProd, a Universal Natural Product database for materia medica of ITM, is currently host to 2696 monographs, from herbal to animal to mineral compounds in 16 diverse attributes such as origin and scientific name. Currently, systems biology, and more precisely systems medicine and pharmacology, can be an aid in providing rationalizations for many traditional medicines and elucidating a great deal of knowledge they can offer to guide future research in medicine. Conclusions. A database of materia medica is a stepping stone in creating a systems pharmacology platform of ITM that encompasses the relationships between the drugs, their targets, and diseases. UNaProd is hyperlinked to IrGO and CMAUP databases for Mizaj and molecular features, respectively, and it is freely available at http://jafarilab.com/unaprod/.


2019 ◽  
Vol 58 (06) ◽  
pp. 194-204 ◽  
Author(s):  
Hassan Shojaee-Mend ◽  
Haleh Ayatollahi ◽  
Azam Abdolahadi

Abstract Background Development of ontologies in traditional medicine can be a foundation for other applications of informatics in this field. Despite the importance of the development of ontologies in traditional medicine, there are few review studies in this area. This study aims to review different methods for ontology development and evaluation in traditional medicine. Methods This review study was performed in 2019. To find related papers, six databases including Scopus, Web of Science, PubMed, Embase, IEEE Xplore, and SpringerLink were searched. Initially, 761 articles were identified. After applying inclusion and exclusion criteria, 22 articles were selected to review different methods for ontology development and evaluation in traditional medicine. Results Five different methods were used for ontology development in traditional medicine, namely conventional, customized, semiautomatic, upper-level, and large-scale methods. The results showed that ontology evaluation was only considered in 32% of the studies. The common methods used for ontology evaluation were competency questions, expert-based evaluation, and automatic detection of inconsistency errors. Conclusion Development of ontologies is of high importance for organizing knowledge in traditional medicine, as this branch of medicine is often not documented or is documented in local languages. The results of this study can help ontology developers to be familiar with the common methods of ontology development and evaluation in traditional medicine and use them for future research.


Planta Medica ◽  
2010 ◽  
Vol 76 (12) ◽  
Author(s):  
F Naghibi ◽  
M Mosaddegh ◽  
S Esmaeili

2021 ◽  
pp. 004208592110179
Author(s):  
Audrey Addi-Raccah ◽  
Paola Dusi ◽  
Noa Seeberger Tamir

We present an empirical overview of current research in the area of parental involvement (PI) based on a bibliometric analysis of 544 articles published between 2014 and 2018, and a thematic review of 39 of the Q1-journal articles in the sample, which contributed to a more detailed illustration of the knowledge base of PI research. The findings reveal an ongoing increase in the intensity of research in five distinct foci. The research is shown to be largely urban- and US-centric and dominated by diverse psychological and sociological perspectives. Implications and avenues for future research have been suggested.


2021 ◽  
pp. 238008442110144
Author(s):  
N.R. Paul ◽  
S.R. Baker ◽  
B.J. Gibson

Introduction: Patients’ decisions to undergo major surgery such as orthognathic treatment are not just about how the decision is made but what influences the decision. Objectives: The primary objective of the study was to identify the key processes involved in patients’ experience of decision making for orthognathic treatment. Methods: This study reports some of the findings of a larger grounded theory study. Data were collected through face-to-face interviews of patients who were seen for orthognathic treatment at a teaching hospital in the United Kingdom. Twenty-two participants were recruited (age range 18–66 y), of whom 12 (male = 2, female = 10) were 6 to 8 wk postsurgery, 6 (male = 2, female = 4) were in the decision-making stage, and 4 (male = 0, female = 4) were 1 to 2 y postsurgery. Additional data were also collected from online blogs and forums on jaw surgery. The data analysis stages of grounded theory methodology were undertaken, including open and selective coding. Results: The study identified the central role of dental care professionals (DCPs) in several underlying processes associated with decision making, including legitimating, mediating, scheduling, projecting, and supporting patients’ decisions. Six categories were related to key aspects of decision making. These were awareness about their underlying dentofacial problems and treatment options available, the information available about the treatment, the temporality of when surgery would be undertaken, the motivations and expectation of patients, social support, and fear of the surgery, hospitalization, and potentially disliking their new face. Conclusion: The decision-making process for orthognathic treatment is complex, multifactorial, and heavily influenced by the role of DCPs in patient care. Understanding the magnitude of this role will enable DCPs to more clearly participate in improving patients’ decision-making process. The findings of this study can inform future quantitative studies. Knowledge Transfer Statement: The results of this study can be used both for informing clinical practice around enabling decision making for orthognathic treatment and also for designing future research. The findings can better inform clinicians about the importance of their role in the patients’ decision-making process for orthognathic treatment and the means to improve the patient experience. It is suggested that further research could be conducted to measure some of the key constructs identified within our grounded theory and assess how these change during the treatment process.


2014 ◽  
Vol 2014 ◽  
pp. 1-32 ◽  
Author(s):  
Shamkant B. Badgujar ◽  
Vainav V. Patel ◽  
Atmaram H. Bandivdekar

Foeniculum vulgareMill commonly called fennel has been used in traditional medicine for a wide range of ailments related to digestive, endocrine, reproductive, and respiratory systems. Additionally, it is also used as a galactagogue agent for lactating mothers. The review aims to gather the fragmented information available in the literature regarding morphology, ethnomedicinal applications, phytochemistry, pharmacology, and toxicology ofFoeniculum vulgare. It also compiles available scientific evidence for the ethnobotanical claims and to identify gaps required to be filled by future research. Findings based on their traditional uses and scientific evaluation indicates thatFoeniculum vulgareremains to be the most widely used herbal plant. It has been used for more than forty types of disorders. Phytochemical studies have shown the presence of numerous valuable compounds, such as volatile compounds, flavonoids, phenolic compounds, fatty acids, and amino acids. Compiled data indicate their efficacy in severalin vitroandin vivopharmacological properties such as antimicrobial, antiviral, anti-inflammatory, antimutagenic, antinociceptive, antipyretic, antispasmodic, antithrombotic, apoptotic, cardiovascular, chemomodulatory, antitumor, hepatoprotective, hypoglycemic, hypolipidemic, and memory enhancing property.Foeniculum vulgarehas emerged as a good source of traditional medicine and it provides a noteworthy basis in pharmaceutical biology for the development/formulation of new drugs and future clinical uses.


2016 ◽  
Vol 22 (2) ◽  
pp. 344-346
Author(s):  
Narges Motahari Tabari ◽  
Seyde Sedighe Yousefi ◽  
Ghazaleh Heydarirad ◽  
Maryam Kardan Soraki ◽  
Payam Habibipour

Exercise, in Iranian traditional medicine, is 1 of the 6 principles recommended for maintaining good health. There are some considerations that must be taken into account before, during, and after exercise. Exercise has different terms in different individuals, seasons, and ages. According to these principles, the interval between exercise and eating food is very important. Exercise after eating is inappropriate, and it is recommended that the best time for exercise is after food has been completely digested and before the next meal. According to the opinion of traditional medicine philosophers, exercise should be done after the complete digestion of food. Exercise may be more effective if it is done according to traditional medicine view at appropriate times and conditions with sufficient intensity and duration.


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