scholarly journals Density of Nocturnal Mammals in a Forest Patch in Bangladesh

2020 ◽  
Author(s):  
Hassan Al-Razi ◽  
Sabit Hasan ◽  
Tanvir Ahmed ◽  
Sabir Bin Muzaffar
Keyword(s):  
Distance Sampling ◽  
Apex Predators ◽  
Slow Loris ◽  
Forest Patch ◽  
Term Survival ◽  
Wide Range ◽  
The Common ◽  
Nocturnal Mammals ◽  
Severe Disturbance

Tropical forests harbor complex communities that are linked together by biotic relationships. Asian forests in particular have lost many apex predators due to habitat loss. We studied a small forest patch in northeastern Bangladesh, Satchari National Park, to determine density and diversity of nocturnal mammals and evaluate their relationships. Transects were walked from February 2015 to July 2016 and density was estimated using distance sampling. Nine species of mammals (5 arboreal and 4 ground-dwelling) were encountered. Densities of the common palm civets, Paradoxurus hermaphrodites, Bengal slow loris, Nycticebus bengalensis, were the highest (19.48 and 15.03 individuals/km2). Density of small Indian civets, large Indian civets and Indian mongoose were lower (2.31-5.55 individuals/km2). Unexpectedly, a wide range of nocturnal mammals co-existed in this forest patch, in spite of fragmentation and severe disturbance. We did not find any significant association between any of the species studied, although this could be an artifact of low sample size. Conservation in Bangladesh remains a challenge due to high human population density. Thus, strict conservation measures are needed to permit the long-term survival of these species.

scholarly journals From young massive star clusters to old globulars: long-term survival chances

2006 ◽  
Vol 2 (S237) ◽  
pp. 408-408
Author(s):  
Richard de Grijs
Keyword(s):  
Galaxy Formation ◽  
Massive Star ◽  
Cluster Formation ◽  
Star Clusters ◽  
Term Survival ◽  
Star Forming ◽  
Distant Galaxies ◽  
Wide Range ◽  
Galaxy Collisions

Young, massive star clusters (YMCs) are the most notable and significant end products of violent star-forming episodes triggered by galaxy collisions and close encounters. The question remains, however, whether or not at least a fraction of the compact YMCs seen in abundance in extragalactic starbursts, are potentially the progenitors of (≳10 Gyr) old globular cluster (GC)-type objects. If we could settle this issue convincingly, one way or the other, the implications of such a result would have far-reaching implications for a wide range of astrophysical questions, including our understanding of the process of galaxy formation and assembly, and the process and conditions required for star (cluster) formation. Because of the lack of a statistically significant sample of YMCs in the Local Group, however, we need to resort to either statistical arguments or to the painstaking approach of case-by-case studies of individual objects in more distant galaxies.

scholarly journals Constitutive expression of bcl-2 in B cells causes a lethal form of lupuslike autoimmune disease after induction of neonatal tolerance to H-2b alloantigens.

1996 ◽  
Vol 183 (6) ◽  
pp. 2523-2531 ◽  
Author(s):  
M López-Hoyos ◽  
R Carrió ◽  
R Merino ◽  
L Buelta ◽  
S Izui ◽  
...  
Keyword(s):  
B Cells ◽  
Autoimmune Disease ◽  
Constitutive Expression ◽  
Systemic Autoimmune Disease ◽  
Spleen Cells ◽  
Term Survival ◽  
F1 Hybrid ◽  
Wide Range

The bcl-2 protooncogene has been shown to provide a survival signal to self-reactive B cells, but it fails to override their developmental arrest after encounter with antigen. Furthermore, constitutive expression of bcl-2 in B cells does not promote the development of autoimmune disease in most strains of mice, indicating that signals other than those conferred by bcl-2 are required for long-term survival and differentiation of self-reactive B cells in vivo. To further examine the factors that are required for the pathogenesis of autoimmune disease, we have assessed the effect of bcl-2 overexpression on the development of host-versus-graft disease, a self-limited model of systemic autoimmune disease. In this model, injection of spleen cells from (C57BL/6 x BALB/c)F1 hybrid mice into BALB/c newborn parental mice induces immunological tolerance to donor tissues and activation of autoreactive F1 donor B cells through interactions provided by allogeneic host CD4+ T cells. BALB/c newborns injected with spleen cells from (C57BL/6 x BALB/c)F1 mice expressing a bcl-2 transgene in B cells developed high levels of anti-single-stranded DNA and a wide range of pathogenic autoantibodies that were not or barely detectable in mice injected with nontransgenic spleen cells. In mice injected with transgenic B cells, the levels of pathogenic autoantibodies remained high during the course of the study and were associated with long-term persistence of donor B cells, development of a severe autoimmune disease, and accelerated mortality. These results demonstrate that bcl-2 can provide survival signals for the maintenance and differentiation of autoreactive B cells, and suggest that both increased B cell survival and T cell help play critical roles in the development of certain forms of systemic autoimmune disease.

scholarly journals The tonkin snub-nosed monkey Rhinopithecus avunculus population in the Quan Ba forest, north-east Vietnam: an identification of priority habitat for conservation

2019 ◽  
Vol 41 (3) ◽  
Author(s):  
Nguyen Xuan Dang ◽  
Nguyen Xuan Nghia ◽  
Pham Van The
Keyword(s):  
Conservation Area ◽  
Forest Patch ◽  
Term Survival ◽  
Forest Farming ◽  
North East ◽  
Broad Leaved Forest ◽  
Priority Habitat ◽  
The Hill ◽  
Leaved Forest

The Tonkin Snub-nosed Monkey Rhinopithecus avunculus is among the World’s 25 most endangered primates. At present, the species is found only in few forest areas in Ha Giang and Tuyen Quang Provinces, north-east Vietnam with a total number not exceeding 250 individuals.  The forest block in Cao Ma Po, Ta Van and Tung Vai Communes of Quan Ba District, Ha Giang Province (the Cao - Ta - Tung forest) harbors the second largest population of Tonkin Snub-nosed Monkey. This population was estimated to be conisted of about 30–35 individuals in 2007.  However, it faces a number of serious threats (wildlife hunting, habitat degradation by widespread forest farming of Tsao-ko cardamom plant, etc.) that may lead the population to be extinct in near future. The population was reduced to 15–21 individuals in 2016 due to these threats. In 2017–2018, we conducted a study to identify a priority habitat area to establish the Quan Ba Tonkin Snub-nosed Monkey Conservation Area. The results of our study show that the distribution of  the Quan Ba Tonkin Snub-nosed Monkey  population is  confined to a small area (about 5,000 ha) belonging to the Theng Chu Phin, Dao Dan Chai, Ta Lay mountains, the Hill 754 and a forest patch along the Vietnam-China  border  from the Post 283  to Post 295. This area harbors the best forest of the Cao - Ta - Tung area. The forest covers 92.3% of the area, and only 7.7% of the area is a non-forest land. There are two types of forest: evergreen broad-leaved forest (50.0% of total area) and limestone evergreen broad-leaved forest (42.3%).  The evergreen broad-leaved forest has been degraded to medium and restoration status. Tsao-ko cardamom Amomum tsao-ko fields are widespread. The limestone evergreen broad-leaved forest of almost primary status remains in very steep slopes and limestone mountains. The Cao - Ta - Tung forest was designated as a watershed protection forest that allows farming of agricultural and medicinal plants inside the forest and the forest farming of Tsao-ko cardamom is widespread becoming the most serious threat to the long-term survival of the Tonkin Snub-nosed Monkey population. In order to ensure long-term survival of the Quan Ba Tonkin Snub-nosed Monkey population, the  area of the Theng Chu Pin, Dao Dai Chai, Ta Lay, Tung Lau mountains,  the Hill 754 and a forest patch along the Vietnam-China border from the Post 283 to Post 285 must be designated as a special-use forest, i.e. to establish a Quan Ba Tonkin Snub-nosed Monkey Conservation Area. 

scholarly journals The tonkin snub-nosed monkey Rhinopithecus avunculus population in the Quan Ba forest, north-east Vietnam: an identification of priority habitat for conservation

2019 ◽  
Vol 41 (3) ◽  
Author(s):  
Nguyen Xuan Dang ◽  
Nguyen Xuan Nghia ◽  
Pham Van The
Keyword(s):  
Conservation Area ◽  
Forest Patch ◽  
Term Survival ◽  
Forest Farming ◽  
North East ◽  
Broad Leaved Forest ◽  
Priority Habitat ◽  
The Hill ◽  
Leaved Forest

The Tonkin Snub-nosed Monkey Rhinopithecus avunculus is among the World’s 25 most endangered primates. At present, the species is found only in few forest areas in Ha Giang and Tuyen Quang Provinces, north-east Vietnam with a total number not exceeding 250 individuals.  The forest block in Cao Ma Po, Ta Van and Tung Vai Communes of Quan Ba District, Ha Giang Province (the Cao - Ta - Tung forest) harbors the second largest population of Tonkin Snub-nosed Monkey. This population was estimated to be conisted of about 30–35 individuals in 2007.  However, it faces a number of serious threats (wildlife hunting, habitat degradation by widespread forest farming of Tsao-ko cardamom plant, etc.) that may lead the population to be extinct in near future. The population was reduced to 15–21 individuals in 2016 due to these threats. In 2017–2018, we conducted a study to identify a priority habitat area to establish the Quan Ba Tonkin Snub-nosed Monkey Conservation Area. The results of our study show that the distribution of  the Quan Ba Tonkin Snub-nosed Monkey  population is  confined to a small area (about 5,000 ha) belonging to the Theng Chu Phin, Dao Dan Chai, Ta Lay mountains, the Hill 754 and a forest patch along the Vietnam-China  border  from the Post 283  to Post 295. This area harbors the best forest of the Cao - Ta - Tung area. The forest covers 92.3% of the area, and only 7.7% of the area is a non-forest land. There are two types of forest: evergreen broad-leaved forest (50.0% of total area) and limestone evergreen broad-leaved forest (42.3%).  The evergreen broad-leaved forest has been degraded to medium and restoration status. Tsao-ko cardamom Amomum tsao-ko fields are widespread. The limestone evergreen broad-leaved forest of almost primary status remains in very steep slopes and limestone mountains. The Cao - Ta - Tung forest was designated as a watershed protection forest that allows farming of agricultural and medicinal plants inside the forest and the forest farming of Tsao-ko cardamom is widespread becoming the most serious threat to the long-term survival of the Tonkin Snub-nosed Monkey population. In order to ensure long-term survival of the Quan Ba Tonkin Snub-nosed Monkey population, the  area of the Theng Chu Pin, Dao Dai Chai, Ta Lay, Tung Lau mountains,  the Hill 754 and a forest patch along the Vietnam-China border from the Post 283 to Post 285 must be designated as a special-use forest, i.e. to establish a Quan Ba Tonkin Snub-nosed Monkey Conservation Area. 

scholarly journals Epidemiology and long-term outcome in outpatients with chronic heart failure in Northwestern Europe

Heart ◽  
2019 ◽  
Vol 105 (16) ◽  
pp. 1252-1259 ◽  
Author(s):  
Hanna Fröhlich ◽  
Niklas Rosenfeld ◽  
Tobias Täger ◽  
Kevin Goode ◽  
Syed Kazmi ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Ejection Fraction ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Term Survival ◽  
Period 2 ◽  
Wide Range ◽  
Ambulatory Patients

ObjectiveTo describe the epidemiology, long-term outcomes and temporal trends in mortality in ambulatory patients with chronic heart failure (HF) with reduced (HFrEF), mid-range (HFmrEF) or preserved ejection fraction (HFpEF) from three European countries.MethodsWe identified 10 312 patients from the Norwegian HF Registry and the HF registries of the universities of Heidelberg, Germany, and Hull, UK. Patients were classified according to baseline left ventricular ejection fraction (LVEF) and time of enrolment (period 1: 1995–2005 vs period 2: 2006–2015). Predictors of mortality were analysed by use of univariable and multivariable Cox regression analyses.ResultsAmong 10 312 patients with stable HF, 7080 (68.7%), 2086 (20.2%) and 1146 (11.1%) were classified as having HFrEF, HFmrEF or HFpEF, respectively. A total of 4617 (44.8%) patients were included in period 1, and 5695 (55.2%) patients were included in period 2. Baseline characteristics significantly differed with respect to type of HF and time of enrolment. During a median follow-up of 66 (33–105) months, 5297 patients (51.4%) died. In multivariable analyses, survival was independent of LVEF category (p>0.05), while mortality was lower in period 2 as compared with period 1 (HR 0.81, 95% CI 0.72 to 0.91, p<0.001). Significant predictors of all-cause mortality regardless of HF category were increasing age, New York Heart Association functional class, N-terminal pro-brain natriuretic peptide and use of loop diuretics.ConclusionAmbulatory patients with HF stratified by LVEF represent different phenotypes. However, after adjusting for a wide range of covariates, long-term survival is independent of LVEF category. Outcome significantly improved during the last two decades irrespective from type of HF.

scholarly journals Physiological Impairment as a Result of Bile Accumulation in an Apex Predator, the Tiger Shark (Galeocerdo cuvier Péron & Lesueur, 1822)

Animals ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. 2030
Author(s):  
Natascha Wosnick ◽  
Ana Paula Chaves ◽  
Yuri Vieira Niella ◽  
Veronica Takatsuka ◽  
Fábio Hissa Vieira Hazin ◽  
...  
Keyword(s):  
Bile Secretion ◽  
Lipid Absorption ◽  
Tiger Shark ◽  
Apex Predators ◽  
Term Survival ◽  
Galeocerdo Cuvier ◽  
Physiological Alterations ◽  
High Lipid ◽  
Physiological Adaptations

Physiological adaptations have evolved to help sharks face rapid periods of feast. Tiger sharks are generalist apex predators that rely on a high-lipid/protein diet. To achieve a satisfactory nutritional condition, proper lipid absorption and hepatic storage are needed. Bile secretion in sharks is low and sporadic but increases during short periods of fasting. The present study describes a physiological impairment caused by bile accumulation in juvenile tiger sharks, possibly due to prolonged fasting. These evidences suggest that, even though sharks have adaptations that prevent them from dying from starvation, alarming physiological alterations might occur. Future studies are needed to assess how such a condition can affect wild populations, as well as possible sublethal consequences that could impact their long-term survival.

Evaluation of combined modality treatment for advanced nasopharyngeal carcinoma by induction chemotherapy and radiotherapy

2006 ◽  
Vol 24 (18_suppl) ◽  
pp. 15544-15544
Author(s):  
T. Q. Tran ◽  
V. V. Vu ◽  
D. K. Vo ◽  
K. C. Pham
Keyword(s):  
Induction Chemotherapy ◽  
Overall Response Rate ◽  
Combined Treatment ◽  
Response Rates ◽  
Cancer Center ◽  
Combined Modality Treatment ◽  
Term Survival ◽  
Overall Response ◽  
The Common

15544 Background: We performed a retrospective investigation of the combined induction chemotherapy and radiotherapy for advanced nasopharyngeal carcinomas at Cancer Center-Ho Chi Minh City-Vietnam. Method: In the period 1998–2000, the treatment regimen induced 2 or 3 cycles of cisplatin and 5-Fluorouracile followed by radiation. Cisplatin was given in the dose of 100 mg/m2/day 1 and 5FU 1,000 mg/m2/d1–4. Radiotherapy included 2 lateral cervical portals and an anterior cervical portal with Cobalt 60. Results: One hundred sixteen patients (92 men and 24 women) with age ranging from 15 to 72 years were enrolled. The overall response rate to induction chemotherapy was 66% (15% complete responses (CRs) and 51% partial responses (PRs)). After combined treatment, overall response rates was 92% (82% CRs, 10% PRs). Toxicities in the chemotherapy were mainly myelosuppression (40%), nausea/vomiting (27%), mucositis (28%), and diarrhea (12%). There was 9 recurrences (2 local, 7 distant), 7 deaths and 1 refusal of radiotherapy. Conclusion: The immediate local response rates was rather high despite of the common of major myelotoxicities and expensive cost. The long-term survival benefit need to be reevaluated carefully later. No significant financial relationships to disclose.

scholarly journals Survival of and In Situ Gene Expression by Vibrio vulnificus at Varying Salinities in Estuarine Environments

2007 ◽  
Vol 74 (1) ◽  
pp. 182-187 ◽  
Author(s):  
Melissa K. Jones ◽  
Elizabeth Warner ◽  
James D. Oliver
Keyword(s):  
Gene Expression ◽  
Vibrio Vulnificus ◽  
Natural Habitat ◽  
Term Survival ◽  
Long Term Survival ◽  
Wide Range ◽  
Opportunistic Human Pathogen

ABSTRACT The opportunistic human pathogen Vibrio vulnificus survives in a wide range of ecological environments, which demonstrates its ability to adapt to highly variable conditions. Survival and gene expression under various conditions have been extensively studied in vitro; however, little work has been done to evaluate this bacterium in its natural habitat. Therefore, this study monitored the long-term survival of V. vulnificus in situ and simultaneously evaluated the expression of stress (rpoS, relA, hfq, and groEL) and putative virulence (vvpE, smcR, viuB, and trkA) genes at estuarine sites of varying salinity. Additionally, the survival and gene expression of an rpoS and an oxyR mutant were examined under the same conditions. Differences between the sampling sites in the long-term survival of any strain were not seen. However, differences were seen in the expression of viuB, trkA, and relA but our findings differed from what has been previously shown in vitro. These results also routinely demonstrated that genes required for survival under in vitro stress or host conditions are not necessarily required for survival in the water column. Overall, this study highlights the need for further in situ evaluation of this bacterium in order to gain a true understanding of its ecology and how it relates to its natural habitat.

Effect of Revascularization on Long-Term Survival in Patients With Ischemic Left Ventricular Dysfunction and a Wide Range of Viability

2010 ◽  
Vol 106 (2) ◽  
pp. 187-192 ◽  
Author(s):  
Stephen G. Sawada ◽  
Saumyadip Dasgupta ◽  
James Nguyen ◽  
Kathleen A. Lane ◽  
Irmina Gradus-Pizlo ◽  
...  
Keyword(s):  
Left Ventricular Dysfunction ◽  
Ventricular Dysfunction ◽  
Left Ventricular ◽  
Term Survival ◽  
Long Term Survival ◽  
Wide Range

scholarly journals Diversity of immune strategies explained by adaptation to pathogen statistics

2015 ◽  
Author(s):  
Andreas Mayer ◽  
Thierry Mora ◽  
Olivier Rivoire ◽  
Aleksandra M Walczak
Keyword(s):  
Mathematical Framework ◽  
Bet Hedging ◽  
Term Survival ◽  
Immune Systems ◽  
Immune Mechanisms ◽  
Pathogen Dynamics ◽  
Wide Range ◽  
Two Parameters ◽  
Biological Organisms

Biological organisms have evolved a wide range of immune mechanisms to defend themselves against pathogens. Beyond molecular details, these mechanisms differ in how protection is acquired, processed and passed on to subsequent generations -- differences that may be essential to long-term survival. Here, we introduce a mathematical framework to compare the long-term adaptation of populations as a function of the pathogen dynamics that they experience and of the immune strategy that they adopt. We find that the two key determinants of an optimal immune strategy are the frequency and the characteristic timescale of the pathogens. Depending on these two parameters, our framework identifies distinct modes of immunity, including adaptive, innate, bet-hedging and CRISPR-like immunities, which recapitulate the diversity of natural immune systems.

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