scholarly journals CO-St (COVID 19- study): impact of the management of men versus women in the treatment of Covid 19. A Multi-Centric Observational study

2021 ◽  
Author(s):  
Tiziana Ciarambino ◽  
filomena pietrantonio ◽  
Sara Rotunno ◽  
Alessandra Fiorentini ◽  
Rosalba Cipriani ◽  
...  
Keyword(s):  
Oxygen Therapy ◽  
Signs And Symptoms ◽  
Epidemiological Data ◽  
Cross Sectional Study ◽  
Antiviral Drugs ◽  
Laboratory Findings ◽  
Cross Sectional ◽  
Significant Difference ◽  
Rehabilitation Ward ◽  
Epidemiological Link

Background: from December 2019 and the spreading of syndemics, a lot of medical centers reg-istered data about their patients. In Italy, the most relevant quantity of patients was hospitalized in internal medicine wards. Methods: In this observational, retrospective cross-sectional study, all data of the COVID-19 patients, admitted Latio hospitals, from March 01 to December 31, 2020, were collected and their Epidemiological data, demographics, signs and symptoms on admission, comorbidities, laboratory findings, chest radiography and CT findings, treatment received and mortality rate were analyzed by gender to find any differences of gravity of disease. Clinician details were registered on database (one for every hospital). Cost analysis was performed by length of stay and antiviral drugs use, using point of view of Italian Healthcare System. Results: 2256 patients with mean age of 71.01 ± 28.02 years were included. For men, frequency of hyper-tension, COPD, use of oxygen therapy, Tocilizumab were significantly higher and epidemiolog-ical link was related to rehabilitation ward and community. The gender difference about hospi-talization was one day more for man. No strong significant difference by gender in the death rate was observed. Considering antiviral drugs and hospitalization, a man costs €1000 more than woman. Conclusions: In male patients, hypertension and COPD were observed more frequently and the epidemiological link was related to rehabilitation ward and community. In female sub-jects, the epidemiological link was related to Hospital and we observed significantly higher atypical chest-X ray. Tocilizumab, oxygen therapy and antiviral drugs were prescribed more in male subjects. No differences by gender we report in other treatments and outcomes. Future studies should be analyzed to get a more comprehensive understanding of COVID-19 by gender.

A Cross-Sectional Study to Compare Differences on Clinical and Laboratory Findings in Children with Seropositive and Seronegative Lupus

2021 ◽  
Author(s):  
Shima Salehi ◽  
Rozita Hosseini Shamsabadi ◽  
Hassan Otukesh ◽  
Reza Shiari ◽  
Monir Sharafi
Keyword(s):  
Autoimmune Disease ◽  
Disease Diagnosis ◽  
Cross Sectional Study ◽  
Rapid Identification ◽  
The Body ◽  
Musculoskeletal Symptoms ◽  
Laboratory Findings ◽  
Cross Sectional ◽  
Significant Difference ◽  
History Of

Abstract Background: Lupus is an inflammatory and autoimmune disease that involves various tissues and organs of the body. Identification of diagnostic elements to rapid identification of seronegative lupus cases is very important in order to prevent morbidity and progression of disease. This study aimed to compare clinical and laboratory findings of seropositive cases with seronegative lupus patients. Methods: This cross-sectional analytic study was performed on 43 children (17 seronegative and 26 seropositive) with lupus who were admitted to Ali Asghar Hospital during 2007-2017. Seropositive patients had anti-nuclear antibody (ANA) titration >1/80, while seronegative patients had ANA titration <1/80 (at the time of disease diagnosis). Clinical and laboratory findings were compared between two groups.Results: Serositis in patients with ANA- was significantly higher than ANA+ (41.17% vs. 23.07%; p = 0.042). ANA- group had higher autoimmune disease history than ANA+ group (42.85% vs. 15.0%; p = 0.041). The family history of the disease in the ANA- group was greater than ANA+ group (50% vs. 23.52%). The percentage of hypertensive patients in ANA- group was higher than ANA+ group (52.94% vs. 26.92%; p = 0.037). Neurologic symptoms in ANA+ and ANA- groups were 38.46% and 17.64%, respectively (p = 0.043). The frequency of patients with thrombocytopenia in ANA+ group was significantly greater than ANA- group (32% vs. 12.5%; p=0.041). There was no significant difference in other clinical and laboratory findings between two groups. Conclusion: Seronegative lupus patients had higher percentage of musculoskeletal symptoms, autoimmune disease history, familial history of disease, and hypertension, while neurological and thrombocytopenia symptoms were higher in seropositive patients compared to seronegative cases. Therefore, evaluation of these factors can be helpful to diagnosis of seronegative patients.

scholarly journals Teething Problems and Parental Beliefs in Nigeria

2009 ◽  
Vol 10 (4) ◽  
pp. 75-82 ◽  
Author(s):  
Foluso J. Owotade ◽  
Morenike O. Folayan ◽  
Temitope A. Esan ◽  
Elizabeth O. Oziegbe ◽  
Comfort A. Adekoya-Sofowora
Keyword(s):  
Signs And Symptoms ◽  
Cross Sectional Study ◽  
Parental Beliefs ◽  
Cross Sectional ◽  
Socioeconomic Class ◽  
Low Socioeconomic ◽  
Significant Difference ◽  
And Gender ◽  
Symptoms And Signs ◽  
Rule Out

Abstract Aim To determine signs and symptoms associated with teething, parental beliefs about teething, and the effects of socioeconomic status on teething in Nigerian children. Methods and Materials A cross-sectional study consisting of 1,013 mothers of children between the ages four to 36 months who visited the immunization clinics at the Community Health Centres in Ife Central and Ife East Local Government Areas. Data was analyzed using STATA (Intercooled release 9) for Windows. Results A total of 765 mothers (75.5%) reported systemic signs and symptoms in their children. Fever (51.8%), diarrhea (12.5%), and vomiting (2.9%) were the most prevalent symptoms and signs reported. Teething problems were reported by 60% of mothers from a high socioeconomic class, as well as 76.7% and 77.9% from middle and low socioeconomic classes, respectively. Interestingly, 65.5% of mothers believed teething should be accompanied with systemic signs and symptoms such as fever (42.1%), diarrhea (13.9%), and vomiting (0.6%). No significant difference was noted between breastfeeding status, gender of the child, and reported systemic signs and symptoms noticed by the mothers. Conclusion Most mothers in the study reported signs and symptoms adduced to teething in their children irrespective of their beliefs. Fever ranked highest of the signs and symptoms reported. Mothers of children from the high socioeconomic class reported fewer teething symptoms. Breastfeeding status and gender of the child had no effect on teething problems in the children studied. Clinical Significance Most signs and symptoms adduced to teething by parents may actually be due to underlying infections. Thus, there is a need to rule out occult infection during the tooth eruption period. Citation Oziegbe EO, Folayan MO, Adekoya-Sofowora CA, Esan TA, Owotade FJ. Teething Problems and Parental Beliefs in Nigeria. J Contemp Dent Pract 2009 July; (10)4:075-082.

scholarly journals Risk factors associated with COVID-19 Intensive Care Unit hospitalisation in Guyana: A cross-sectional study

2021 ◽  
Author(s):  
Steven A. Seepersaud
Keyword(s):  
Risk Factors ◽  
Retrospective Chart Review ◽  
Binary Logistic Regression ◽  
Signs And Symptoms ◽  
Cross Sectional Study ◽  
Laboratory Findings ◽  
Cross Sectional ◽  
Factors Associated ◽  
Independent Variables ◽  
Icu Admission

Objective The purpose of the study was to determine risk factors associated with COVID-19 ICU hospitalisation at Georgetown Public Hospital Corporation (GPHC), Guyana. Methods A retrospective chart-review was conducted on all COVID-19 admissions from March to September 2020. The predictive factors were demographics, comorbidities, signs and symptoms of COVID-19 and laboratory findings on admission. Descriptive frequency analysis was done for all independent variables and the Chi-square test was used to compare differences between groups where suitable. Univariate and multivariate binary logistic regression was used to examine the association between the independent variables and the risk for ICU hospitalisation. Results There were 136 patients with COVID-19 at GPHC during March to September 2020 and after exclusion, 135 patients were used in the study. There were 72 (53.4%) patients who required non-ICU care, while 63 (46.6%) ICU care and average age ± SD (median) was 51 ±16 (n= 49) and 56 ±18 (n= 60), respectively. In the multivariate regression model, the odds of ICU admission for those aged 40-65 was 0.14 (p <.01) compared to those > 65 years. Patients with class 2 and above obesity had higher odds of ICU admission compared to non-obese patients OR 11.09 (p= .006). Patients with 2 and 3 or more comorbidities also had higher odds of ICU admission compared to those with no comorbidities OR 7.83 (p= .03) and 132 (p <.001), respectively. Patients with LDH 228-454 U/L and > 454 U/L on admission had higher odds of ICU admission compared to those with normal LDH OR 19.88 (p= .001) and 23.32 (p= .001), respectively. Patients with albumin < 3.50 mg/dL on admission also had higher odds of ICU admission compared to those with normal albumin OR 5.78 (p= .005). Conclusion Risk factors associated with ICU hospitalisation were advanced age, obesity, multiple comorbidities, elevated LDH and low albumin. Protecting the population at risk for ICU admission and prioritizing them for vaccination is recommended to reduce the risk of running out of ICU capacity.

Effect of Online Classes on Dry Eye Disease in Children: A Hospital Based Survey

2021 ◽  
Vol 37 (4) ◽  
Author(s):  
Sangameshwarayya Salimath ◽  
Salma Sultana ◽  
Brijesh Appasaheb Patil ◽  
Kalpana R Kulkarni ◽  
Shishir K. Nyamagoudar
Keyword(s):  
Dry Eye ◽  
Signs And Symptoms ◽  
Cross Sectional Study ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
P Value ◽  
Online Classes ◽  
Cross Sectional ◽  
Department Of Ophthalmology ◽  
Significant Difference

Purpose:  To determine the effect of online classes on dry eye disease in children. Study Design:  Cross sectional study. Place and Duration of Study:  Department of Ophthalmology HSK hospital, Navanagar, Bagalkot, India, from October 2020 to November 2020. Methods:  A total of 454 students attending online classes between the ages of 3 – 18 years were selected. Questionnaire was presented which included name, age, sex, residence, duration of online studies and duration in hours per day along with the various signs and symptoms according to SPEED questionnaire. Statistical analysis was performed using the IBM SPSS version 17. Quantitative variables were presented as mean ± standard deviation, while qualitative data was presented as frequency and percentages and compared by chi square test. P-value of < 0.005 was considered as significant. Results:  Of the 454 responses, 316 (69.6%) had symptoms of dry eye disease, of which 159 were girls and 157 boys. There was no significant difference between boys and girls. Children taking online classes for 2 – 3 hours and for 4 to 6 months duration were more affected by the dry eye disease. Based on severity of grading system, 246 (84.2%) had mild symptoms, 42 (9.3%) had moderate symptoms and 28 ([6.2%) had severe symptoms. One hundred and twenty children visited ophthalmologist and 28.5% had their treatment of dry eye started. Conclusion:  Online classes have resulted in increase in the frequency of dry eye disease in children. Proper education about the usage of screen time and educating parents about early treatment is essential. Key Words:  Dry eye disease, Symptoms, Headache, Online learning.

scholarly journals Spino-pelvic radiological parameters in normal Indian population

SICOT-J ◽  
2018 ◽  
Vol 4 ◽  
pp. 14 ◽  
Author(s):  
Roop Singh ◽  
Sushil Kumar Yadav ◽  
Sushma Sood ◽  
Rohtas Kumar Yadav ◽  
Ravi Rohilla
Keyword(s):  
Indian Population ◽  
Epidemiological Data ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Mean Values ◽  
Pelvic Parameters ◽  
Radiographic Parameters ◽  
Study Results ◽  
Significant Difference ◽  
Physiological Values

Introduction: There is increasing emphasis on the sagittal spino-pelvic alignment and its interpretation is of critical importance in the management of spinal disorders. A cross-sectional study of several spino-pelvic radiographic parameters was conducted to determine the physiological values of these parameters, to calculate the variations of these parameters according to epidemiological data, and to study the relationships among these parameters. Material and method: Fifty normal healthy volunteers (29 males and 21 females) with no history of back pain were selected and were subjected to standing sagittal spino-pelvic radiographs. All the measurements of various radiographic parameters were performed with use of a software program. A statistical analysis was done to study the relationships among them. Results: The mean values of pelvic incidence (PI) and lumbar Lordosis Angle (LLA) were 48.52 ± 8.99 and 58.78 ± 9.51, respectively. There was statistical difference between male and female parameters in LLA, lumbo-sacral angle (LSA), sacral horizontal angle (SHA), sacral inclination angle (SIA), sacropelvic angle (PRS1), pelvisacral angle (PSA), and PI. A majority of parameters had higher values for female subjects when compared to male subjects. PI was positively correlated with LLA, pelvic angle (PA), pelvic overhang (PO), pelvic tilt (PT), sacrofemoral distance (SFD), SHA, and sacropelvic translation (SPT), which were highly significant, whereas LLA was positively correlated with SHA and SIA only. PI and LLA were both negatively correlated with PSA, pelvic thickness (PTH), and PRS1. Conclusions: This study presents the various spino-pelvic radiographic parameter values of a sample of the normal asymptomatic Indian population. There was significant difference in radiographic parameters between males and females in about half of the parameters studied in the sample. The values obtained are comparable with the values presented as normal in the literature. A comparison of the study results with data published about other populations revealed no differences in any of the pelvic parameters between the Indian, Brazilian, and Korean populations.

scholarly journals Indicators of Adrenal Insufficiency in TB-suspect Patients Presenting with Signs and Symptoms of Adrenal Insufficiency at Three South African Hospitals in Pretoria

2020 ◽  
Vol 13 (1) ◽  
pp. 178-187
Author(s):  
Langalibalele H. Mabuza ◽  
Daniel F. Sarpong
Keyword(s):  
Adrenal Insufficiency ◽  
District Hospital ◽  
Signs And Symptoms ◽  
Cross Sectional Study ◽  
Serum Glucose ◽  
Cd4 Count ◽  
Fasting Serum ◽  
Laboratory Findings ◽  
Cross Sectional ◽  
Fasting Serum Glucose

Background: Primary adrenal insufficiency occurs when the function of the adrenal cortex to produce cortisol is impaired. Infections, such as disseminated Tuberculosis (TB) and malignancies, are the major causes of Adrenal Insufficiency (AI) in developing countries. AI is characterized by specific symptoms, signs, and laboratory findings. Objective: To determine indicators of AI in TB-suspect patients presenting with signs and symptoms of AI. Methods: A cross-sectional study was conducted at the primary health care ward of Dr. George Mukhari Academic Hospital, Jubilee District Hospital, and Odi District Hospital. The population comprised all TB-suspects, from whom a sample of 75respondents was obtained. A researcher administered questionnaire was used to collect data related to their signs, symptoms, and laboratory findings. Results: Of the 75 respondents, 47 (62.37) and 28 (37.3%) were classified as Adrenal Sufficiency (AS) and AI, respectively. The most occurring symptoms were craving for salt, dry, itchy skin, and vomiting (prevalence: 79.7%, 68.1%, and 69.0%, respectively). Signs or symptoms by themselves did not discriminate persons with a high likelihood of AI. However, a fasting serum glucose (≤ 5.25 mmol/L), a positive GeneXpect, a low CD4 count (≤ 274.5 cells/ml), with a combination of signs and symptoms (9.5) constituted a discriminator for AI in TB-suspect patients (87.5% likelihood). Conclusion: A low fasting serum glucose, a positive GeneXpect, a low CD4 count with a minimum of ten signs and symptoms constitute a discriminator for AI in TB-suspect patients, necessitating treatment initiation to save patient lives in laboratory resource-limited settings.

scholarly journals Signs and symptoms related to inhalation of surgical smoke in the nursing team

2019 ◽  
Vol 23 (3) ◽  
Author(s):  
Ana Claudia Saito ◽  
Amanda Salles Margatho ◽  
Aryane Apolinario Bieniek ◽  
Nathanye Crystal Stanganelli ◽  
Renata Perfeito Ribeiro
Keyword(s):  
Signs And Symptoms ◽  
Cross Sectional Study ◽  
University Hospital ◽  
Cross Sectional ◽  
Surgical Smoke ◽  
Exact Test ◽  
Significant Difference ◽  
Surgical Technologists ◽  
Nursing Professionals ◽  
Electrocautery Smoke

ABSTRACT Objective: To compare the prevalence of signs and symptoms related to inhalation of surgical smoke among surgical technologists and non-surgical technologists nursing professionals. Method: A cross-sectional study with 46 professionals from a university hospital. To evaluate the prevalence, an instrument with signs/symptoms related to the inhalation of electrocautery smoke was used. To verify the comparison between the prevalence of signs/symptoms, the Fisher’s exact test was performed. Results: Higher prevalence of all signs/symptoms among surgical technologists, with a statistically significant difference between the act of instrumenting with the presence of at least one signs/symptoms related to inhalation of surgical smoke (p=0.01); eye irritation (p=0.02); irritation of nasal mucosa and oral cavity (p=0.03); headache (p=0.04). Conclusion: The presence of problems related to surgical smoke in nursing workers elicits more attention. Implications for practice: Health units must be aware of the risk of such exposure and take measures to preventing it.

scholarly journals Clinical and laboratory findings and PCR results in severe and non-severe COVID19 patients based on CURB-65 and WHO severity indices

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Farnaz Karimi ◽  
Mahshid Saleh ◽  
Amir Abbas Vaezi ◽  
Mostafa Qorbani ◽  
Foroogh Alborzi Avanaki
Keyword(s):  
Oxygen Saturation ◽  
Vital Signs ◽  
Signs And Symptoms ◽  
National Guideline ◽  
Inclusion Criteria ◽  
Laboratory Findings ◽  
Cross Sectional ◽  
Chronic Heart Disease ◽  
Significant Difference ◽  
Severity Of The Disease

Abstract Background The importance of clinicolaboratory characteristics of COVID-19 made us report our findings in the Alborz province according to the latest National Guideline for the diagnosis and treatment of COVID-19 in outpatients and inpatients (trial five versions, 25 March 2020) of Iran by emphasizing rRT-PCR results, clinical features, comorbidities, and other laboratory findings in patients according to the severity of the disease. Methods In this study, 202 patients were included, primarily of whom 164 had fulfilled the inclusion criteria. This cross-sectional, two-center study that involved 164 symptomatic adults hospitalized with the diagnosis of COVID-19 between March 5 and April 5, 2020, was performed to analyze the frequency of rRT-PCR results, distribution of comorbidities, and initial clinicolaboratory data in severe and non-severe cases, comparing the compatibility of two methods for categorizing the severity of the disease. Results According to our findings, 111 patients were rRT-PCR positive (67.6%), and 53 were rRT-PCR negative (32.4%), indicating no significant difference between severity groups that were not related to the date of symptoms' onset before admission. Based on the National Guideline, among vital signs and symptoms, mean oxygen saturation and frequency of nausea showed a significant difference between the two groups (P < 0.05); however, no significant difference was observed in comorbidities. In CURB-65 groups, among vital signs and comorbidities, mean oxygen saturation, diabetes, hypertension (HTN), hyperlipidemia, chronic heart disease (CHD), and asthma showed a significant difference between the two groups (P < 0.05), but no significant difference was seen in symptoms. Conclusion In this study, rRT-PCR results of hospitalized patients with COVID-19 were not related to severity categories. From initial clinical characteristics, decreased oxygen saturation appears to be a more common abnormality in severe and non-severe categories. National Guideline indices seem to be more comprehensive to categorize patients in severity groups than CURB-65, and there was compatibility just in non-severe groups of National Guideline and CURB-65 categories.

scholarly journals Pediatric Logistic Organ Dysfunction (PELOD) Score as prognosis of multiple organ failure in sepsis

2010 ◽  
Vol 50 (4) ◽  
pp. 226
Author(s):  
Hendra Hendra ◽  
Ari Lukas Runtunuwu ◽  
Jeanette Irene Chistie Manoppo
Keyword(s):  
Multiple Organ Failure ◽  
Organ Failure ◽  
Cross Sectional Study ◽  
Multiple Organ ◽  
Laboratory Findings ◽  
Cross Sectional ◽  
Logistic Organ Dysfunction ◽  
Emergency Event ◽  
Significant Difference ◽  
Pelod Score

Background Sepsis is an emergency event that often found inpediatric intensive care unit. If this condition is not early detectedand promptly treated, severe complications including septic shockand multiple organ failure may result that can end up as death.Objective To discover alternative measurement as a prognosis ofmultiple organ failure in sepsis.Methods This cross sectional study was conducted in 37 patientsdiagnosed as sepsis. The age of the patients were 1 month until 13years and the patients were hospitalized in child health departmentof R. D. Kandou Hospital during June 2009 – September 2009.Result Bronchopneumonia (18) was the most commoninfection source, followed by gastroenteritis (11), encephalitis(6) and meningitis (2). The bacteria which is found was Proteusmirabilis (5), Citrobacter difersus (5), Staphylococcus aureus (3),Escherichia coli (2) and Acinetobacter baumannii (1). There wasno significant difference in gender distribution, nutrition statusand blood culture between both groups. Laboratory findings andclinical manifestations which included white blood cell (WBC)> 10.000/μL (34), platelet count > 150.000 (27) and bodytemperature 38oC – 39oC (20). There was a correlation betweenPELOD score and multiple organ failure (P=0.02). A higherPELOD score will increase opportunity to get multiple organfailure. In patient with organ failure more than two, PELODscore 0-10 (9 patients), score 11-20 (7 patients), score 21-30 (8patients), and score 31-40 (1 patient).Conclusion There was a correlation between PELOD score andmultiple organ failure in patient with sepsis. A higher PELODscore will increase opportunity to get multiple organ failure.

scholarly journals Cholera Outbreak in Hadhramout, Yemen: The Epidemiological Weeks 2019

2021 ◽  
Vol 8 (1) ◽  
pp. 40-46
Author(s):  
Eidha Ali Bin-Hameed ◽  
Huda Ameen Joban
Keyword(s):  
Epidemiological Data ◽  
Cross Sectional Study ◽  
Laboratory Culture ◽  
Watery Diarrhea ◽  
Contaminated Water ◽  
Age Group ◽  
Cholera Outbreak ◽  
Cross Sectional ◽  
Acute Watery Diarrhea ◽  
Significant Difference

Background and aims: Cholera is a disease of acute watery diarrhea caused by Vibrio cholerae usually transmitted through contaminated water. In this study, we collected and analyzed the related epidemiological data to determine cholera outbreak in Hadhramout, Yemen during the disease epidemic in 2019. Methods: A cross-sectional study was conducted according to screening rapid diagnostic and confirmatory laboratory culture testing methods for diagnosing clinically cholera cases. Results: Suspected cholera cases were tested by rapid diagnostic test (RDT) and 399 (50.5%) out of 794 cases were determined positive, and 76(9.6%) of them were confirmed by laboratory culture test (LCT) with statistically significant difference. Serotype V. cholerae O1 was also detected in patients’ diarrhea. Females were the most affected by the disease manifested in 201 (25.3%) and 43 (5.4%) when tested by RDT and LCT, respectively, with no statistically significant difference. The highest proportion of cholera cases (224) were reported in the age group less than 15 years (56.1%) with statistically significant difference when tested by RDT, and 45(13.3%) when tested by LCT with insignificant statistics difference. Hajr directorate was revealed to be the most affected with 242 (30.47%) followed by Mukalla city directorate with 108 (13.60%) when the cases were tested by RDT; while Hajr and Mukalla city directorates reported 55 (7.0%) and 15 (2.0%), respectively, when it was confirmed by LCT with a statistically significant difference. Conclusion: Severe cholera outbreak occurred during the epidemiological weeks in 2019 in Hadhramout coast. V. cholerae O1 serotype was the causative agent of cholera. Females and age group less than 15 years were the most affected by the disease. Hajr and Mukalla city directorates reported serious outbreak cholera cases.

Sign in / Sign up

Export Citation Format

Share Document