EVALUATION OF ANTI-DIARRHEAL PROPERTY OF CRUDE EXTRACTS AND DIFFERENT FRACTIONS OF STEM BARK AND FRUITS OF OROXYLUM INDICUM

2017 ◽  
pp. 161-168
Author(s):  
Majedul Islam
Keyword(s):  
Stem Bark ◽  
Oroxylum Indicum ◽  
Crude Extracts

Antioxidant and antimicrobial activities of stem bark extracts of Oroxylum indicum Vent. (Bignoniaceae) ‐ A medicinal plant of northeastern India

2011 ◽  
Vol 1 (3) ◽  
pp. 152-157
Author(s):  
Vimal Kumar ◽  
A. K. Chaurasia ◽  
Ashok Naglot ◽  
Reji Gopalakrishnan ◽  
B. J. Gogoi ◽  
...  
Keyword(s):  
Ethyl Acetate Extract ◽  
Water Extract ◽  
Stem Bark ◽  
Antimicrobial Activities ◽  
Chloroform Extract ◽  
Antioxidant Ability ◽  
Oroxylum Indicum ◽  
Ic50 Value ◽  
Trolox Equivalent ◽  
Antioxidant And Antimicrobial Activities

The antioxidant activity of extracts of Oroxylum indicum stem bark wasevaluated using different methods. The ethyl acetate extract (EAE) showedthe lowest IC50 value (0.76 mg/ml) with the highest inhibition of DPPH. In theFRAP assay, the hexane extract (HE) showed the highest ferric reducing abilitywhereas the EAE showed better antioxidant ability with lowest IC50 value(0.80mg/ml) in βCL assay. The EAE and HE showed highest ascorbic acidequivalent (6.60 ± 0.22) and trolox equivalent (2.04 ± 0.07) values in antioxidativecapacity of ACW and ACL in PCL assay. During antimicrobial evaluationHE, Chloroform extract (CE) and EAE were found effective against thetested bacteria while the water extract (WE) showed better activity (14.25 ±0.478) against yeast.

scholarly journals Phytochemical, cytotoxicity and antioxidant studies on the stem bark of Piper arborescens

2017 ◽  
Vol 13 (4) ◽  
pp. 840-845 ◽  
Author(s):  
Nicholas Anak Daniel ◽  
Fasihuddin Badruddin Ahmad ◽  
Zaini Assim ◽  
Chua Hun Pin
Keyword(s):  
Brine Shrimp ◽  
Antioxidant Activities ◽  
Stem Bark ◽  
Artemia Salina ◽  
Methyl Eugenol ◽  
Gas Chromatography Mass Spectrometry ◽  
Caryophyllene Oxide ◽  
Phytochemical Study ◽  
Crude Extracts ◽  
High Cytotoxicity

Phytochemical study on the stem bark of P. arborescens has isolated six secondary metabolites from the crude extracts by using column chromatography, while identification was performed by using Gas Chromatography - Mass Spectrometry (GC-MS), Nuclear Magnetic Resonance (NMR) and Fourier Transform Infrared (FTIR). The isolated metabolites were identified as caryophyllene oxide (1), α-bisabolol (2), benzamide 2-(methylamino) (3), 2-ethylpiperidine (4), piperine (5) and methyl eugenol (6). Toxicity test on the four crude extracts of P. arborescens shows a high cytotoxicity against Artemia salina brine shrimp with LC50 values ranging from 13.12 to 58.70 µg/mL. Greater cytotoxicity of the crude extracts of P. arborescens indicated the presence of potent cytotoxic components in this Piper spp. Antioxidant assay of P. arborescens against 2-diphenyl-1-picrylhydrazyl (DPPH) indicated moderate antioxidant activities of methanol, dichloromethane, chloroform and hexane crude extracts with EC50 values of 21.68, 23.82, 32.88 and 36.88 µg/mL, respectively.

scholarly journals In-vitro Antimicrobial Activities and Phytochemical Screening of Selected Plant Extracts against Some Medically and Agriculturally Important Pathogens

2020 ◽  
pp. 167-189
Author(s):  
Yirgashewa Asfere ◽  
Ameha Kebede ◽  
Dejene Zinabu
Keyword(s):  
Stem Bark ◽  
Antibacterial Activities ◽  
Antimicrobial Activities ◽  
Plant Parts ◽  
Antibacterial And Antifungal Activities ◽  
Ruta Chalepensis ◽  
Crude Extracts ◽  
Growth Inhibitory ◽  
Scientific Justification

In Ethiopia, many plants are used for medicinal drive-by old-style naturopaths without any scientific justification for their therapeutic values. The principal aim of this study were to evaluate the in vitro antibacterial and antifungal activities of the leaf, root and stem bark extracts of Rhamnus prinioides (gesho), Justicia schimperiana (sensel) and Ruta chalepensis (Tena adam) against some common pathogenic species of bacteria and fungi. The results of this study shown that the crude extracts of ethanol, methanol, hexane and water crude extracts had antimicrobial activities on most bacterial and fungi species of some solvent extracts. Ethanol and methanol crude extracts had the highest growth inhibitory effects as compared with those of the aqueous and hexane crude extracts. But, the four solvent crude extracts had fewer antimicrobial activities than commercially available drug(chloramphenicol and clotrimazole). Campylobacter jejuni and Staphylococcus aureus were found to be the most vulnerable microbes to the crude ethanol (99.5%). The growth-inhibitory events of the crude extracts were found to be significantly dissimilar for both concentrations (30 and 60 mg/ml) in all plant parts (p < 0.05). In general, this study did not only indicate that the antibacterial activities of R. prinioides (gesho), J. schimperiana (sensel) and R. chalepensis (Tena adam). It also accesses a scientific justification for its old-style use against some diseases.

scholarly journals Ethnopharmacological Inspections of Organic Extract of Oroxylum indicum in Rat Models: A Promising Natural Gift

2019 ◽  
Vol 2019 ◽  
pp. 1-13 ◽  
Author(s):  
Mst. Marium Begum ◽  
Azharul Islam ◽  
Rayhana Begum ◽  
Md. Sahab Uddin ◽  
Md. Sohanur Rahman ◽  
...  
Keyword(s):  
Liver Enzyme ◽  
Glucose Level ◽  
Stem Bark ◽  
Mucosal Damage ◽  
Enzyme Concentration ◽  
Diabetic Rats ◽  
Gastric Mucosal Damage ◽  
Edema Formation ◽  
Oroxylum Indicum ◽  
Anti Inflammatory

The stem bark of Oroxylum indicum (O. indicum) was aimed at testing for anti-inflammatory, antiulcerative, antihyperglycemic, and antidyslipidemic activities. Liver enzyme concentration (SGPT, SGOT) had also been assessed. After being extracted in organic solvent, 3 distinct doses, 100, 200, and 400 mg/kg b.w. (p.o.), were used. For edema formation 0.1 ml carrageenan at a dose of 1% w/v was injected into paw of left hind. It showed a fall of edemas 37.50%, 48.34%, and 55.83% while used doses were 100, 200, and 400 mg/kg b.w. (p.o.) individually. The EtOH extract of O. indicum (50%) and its fractions PET, CLF, EtOAc, and nBUT were studied against ethanol-induced gastric mucosal damage. Only PET and n-BuOH exhibited the highest percentage of protection and were 96% and 99%, respectively, persuaded by ethanol. In OGTT glibenclamide revealed reduction of glucose level to 7.55 ± 0.22 mmol/L from 10.57 ± 0.32 mmol/L after 30 minutes. Antihyperglycemic activities were assessed for 8- and 12-week duration in diabetic rats. Glibenclamide reduced glucose level from 33.50±0.31 to 7.90±0.19 mmol/L in 12 weeks. In 12 and 8 weeks, combination therapy lowered blood glucose level to a normal extent by 79% and 61% individually. In antidyslipidemic activities after 12-week treatment, it revealed simvastatin; MEOI (400 mg/kg b.w.) and combination of both reduced TC level by 44%, 28%, and 48% consequently followed by TG and LDL. In 8-week treatment, HDL levels were increased by 34%, 13%, and 36%, and in 12 weeks increased by 36%, 8%, and 38% consequently. Liver enzyme concentration after 12 weeks of treatment with glibenclamide, 400 mg/kg b.w. (p.o.) of MEOI and combination of both, exhibited the fact that concentration of SGPT showed downturn by 43.23%, 8.01%, and 54.86% and SGOT by 42.40%, 5.31%, and 44.85%. This study remarked that O. indicum has anti-inflammatory, antiulcer, antidiabetic, and antidyslipidemic potentials but has no ameliorative effect on liver enzyme.

In vitro Antisalmonellal and Antioxidant Properties of Mangifera indica L. Stem Bark Crude Extracts and Fractions

2015 ◽  
Vol 5 (1) ◽  
pp. 29-41 ◽  
Author(s):  
Landric Noghogne ◽  
Donatien Gatsing ◽  
Fotso ◽  
Norbert Kodjio ◽  
Jean Sokoudjou ◽  
...  
Keyword(s):  
Mangifera Indica ◽  
Antioxidant Properties ◽  
Stem Bark ◽  
Crude Extracts
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