scholarly journals Pengaruh Lama Penyeduhan Terhadap Kualitas dan Jumlah Padatan Minuman Kopi Seduh Dingin Kopi Arabika Flores Bajawa

2021 ◽  
Vol 4 (2) ◽  
pp. 7-13
Author(s):  
Rezky Haryono ◽  
Ridawati ◽  
Mariani
Keyword(s):  
Antioxidant Activity ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Reflux Disease ◽  
Coffee Consumption ◽  
Health Benefit ◽  
Benefit And Risk

Kopi merupakan salah satu komoditas yang paling sering diperdagangkan di dunia, dikutip dari website oec.world (2018) dengan total perdagangan 30.9 miliar USD. Mengkonsumsi kopi memiliki banyak manfaat positif, dikutip dari jurnal review on health benefit and risk of coffee consumption mengkonsumsi kafein dalam kopi dapat meningkatkan kinerja fisik, membakar lemak, mengurangi resiko stroke, kanker hati dan prostat sebanyak 20%. Dikutip dari jurnal acidity and antioxidant activity of cold brew (2018) minuman kopi seduh dingin memiliki kadar keasaman yang lebih rendah jika dibandingkan dengan minuman kopi yang diseduh menggunakan air panas, sehingga membuatnya menjadi pilihan yang lebih dapat diterima bagi mereka yang menderita GERD (gastroesophageal reflux disease atau asam lambung) dan maag (www.healthline.com, 2018). Penelitian ini bertujuan untuk meneliti lama penyeduhan yang berbeda-beda (6, 12, 18 dan 24 jam) dengan menguji kualitas minuman kopi seduh dingin dari berbagai aspek kualitas seperti aroma, flavor, balance, aftertaste, acidity, sweetness, body dan jumlah padatan terlarut kepada panelis ahli dengan menggunakan metode eksperimen. Hasil penelitian menunjukan terdapat pengaruh sensoris pada kopi seduh dingin dengan lama penyeduhan yang berbeda-beda. Berdasarkan penelitian, kopi seduh dingin dengan lama penyeduhan 24 jam memiliki nilai tertinggi di setiap aspek dibandingkan dengan waktu penyeduhan 6, 12 dan 18 jam. Dimana pada aspek flavor memiliki nilai 7,02 (very good), balanced memiliki nilai 6,93 (good), aftertaste memiliki nilai 7,01 (very good), avidity memiliki nilai 6,85 (good), sweetness memiliki nilai 6,87 (good) dan body memiliki nilai 6,97 (good).

scholarly journals TOTAL ANTIOXIDANT ACTIVITY AND INFLAMMATION MARKERS DURING PROGRESSION OF GASTROESOPHAGEAL REFLUX DISEASE IN YOUNG PATIENTS WITH AUTOIMMUNE THYROIDITIS

2021 ◽  
Vol 21 (1) ◽  
pp. 44-48
Author(s):  
T.M. Pasiieshvili
Keyword(s):  
Antioxidant Activity ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Autoimmune Thyroiditis ◽  
Reflux Disease ◽  
Young Patients ◽  
Total Antioxidant Activity ◽  
Histological Changes ◽  
Oesophageal Mucosa ◽  
Total Antioxidant

The aim of this study is to establish the content of inflammation markers (tumour necrosis factor alpha and interleukin 18) and the index of total antioxidant activity in young patients with comorbidity between gastroesophageal reflux disease and autoimmune thyroiditis and to determine their dependence on morpho-histological changes in the oesophageal mucosa. Materials and methods. The study involved 182 students aged 18 to 25 years: 120 patients with comorbidity between gastroesophageal reflux disease and autoimmune thyroiditis, 42 those having an isolated course of autoimmune thyroiditis. The methodology included complex clinical, instrumental, immunological, statistical methods. Results. Determining the activity of proinflammatory cytokines has revealed their statistically significant increase. The level of these cytokines depends on morpho-histological changes in the mucous membrane and reaches the maximum during the erosive process. At the same time, the indicator of total antioxidant activity significantly decreases. In this case, the erosive form of the disease is accompanied by more expressive changes in this indicator. Conclusions. The inflammatory process in the oesophagus is accompanied by the activation of the pro-inflammatory segment of immunity against the background of the suppression of the antioxidant system, which is dependent on morphological changes in the oesophageal mucosa. These changes will contribute to the development of pathological apoptosis and the progression of nosologies.

Effects of morphological changes in the esophageal mucosa in gastroesophageal reflux disease on the indicators of the antioxidant system in students with autoimmune thyroiditis

2021 ◽  
Author(s):  
T. M. Pasiieshvili
Keyword(s):  
Antioxidant Activity ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Glutathione Peroxidase ◽  
Reflux Disease ◽  
Manganese Superoxide Dismutase ◽  
Esophageal Mucosa ◽  
Total Antioxidant Activity ◽  
Manganese Superoxide ◽  
Total Antioxidant

Objective — to establish changes in indicators of the antioxidant defence system, taking into account the morphological form of the esophageal mucosa lesions in patients with gastroesophageal reflux disease (GERD), occurring against the background of autoimmune thyroiditis (AIT). Materials and methods. The study involved 120 students with GERD and AIT, aged 18 to 25 years; from them 93 (77.5 %) females and 27 (22.5 %) males. The disease duration did nit exceed 3 years. Fibrogastroduodenoscopic examination has shown an erosive form of gastroesophageal reflux disease in 34 patients (28.3 %) and non‑erosive form of the disease was in 86 cases (71.7 %). Indicators of the total antioxidant activity of glutathione peroxidase and mitochondrial manganese superoxide dismutase were examined. Results. A decrease in the total indicator of the total antioxidant activity was established, which was estimated as the failure of the first phase of the antioxidant defence system. At the same time, an increase in the activity of manganese superoxide dismutase and a decrease in the production of glutathione peroxidase were noted. The levels of total antioxidant activity and glutathione peroxidase correlated with morphological changes in the esophageal mucosa: the presence of the erosive form of the disease had a greater impact on the changes in these parameters. Conclusions. The combined course of gastroesophageal reflux disease and autoimmune thyroiditis in students was accompanied by a decrease in the indicators of total antioxidant activity and glutathione peroxidase and an increase in the activity of manganese superoxide dismutase. The presence of erosions in the esophageal mucosa had a greater impact on the changes in the parameters of total antioxidant activity and glutathione peroxidase.  

scholarly journals Hubungan antara Konsumsi Kopi dengan Gejala Gastroesophageal Reflux Disease (GERD)

2021 ◽  
Vol 2 (1) ◽  
pp. 177-184
Author(s):  
Alika Putri Saraswati ◽  
Efyluk Garianto ◽  
Mulyarjo
Keyword(s):  
Data Analysis ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Significant Relationship ◽  
Reflux Disease ◽  
Coffee Consumption ◽  
Spearman Correlation ◽  
Cross Sectional ◽  
Correlation Test ◽  
Spearman Correlation Test

Introduction: Gastroesophageal Reflux Disease (GERD) is a condition that develops when there is the retrograde flow of gastric contents causing some symptoms or complications. One of the risk factors for GERD is the habit of consuming coffee, which has become a trend in everyday life without realizing it. Purpose: The purpose of this study was to determine the relationship between coffee consumption and symptoms of GERD. Method: This research is an analytic observational study using a cross-sectional study design with a sample size of 86 people. Results: The results showed that most respondents were women with a total of 66 people (73.3%). Of the 86 respondents, 55 people (64%) had coffee consumption habits and 31 people (36%) did not. Respondents who did not have the possibility of suffering from GERD were 74 people (86.0%) and those who had the possibility of suffering GERD were 12 people (14.0%). Data analysis using the Spearman correlation test showed no significant relationship (p = 0.428) between the frequency of coffee consumption and symptoms of GERD. Of the 55 respondents who consumed coffee, 12 respondents (21.8%) consumed ready-to-drink liquid coffee, 19 respondents (34.5%) consumed ground instant coffee, and 24 respondents (43.6%) consumed ground/brewed coffee. Discussion: Data analysis using the Spearman correlation test showed no significant relationship (p = 0.193) between the type of coffee consumed and the symptoms of GERD. The conclusion of this study is that there is no significant relationship between coffee consumption and GERD symptoms in students of the Faculty of Medicine, University of Hang Tuah Surabaya, class 2016-2018.

scholarly journals TOTAL ANTIOXIDANT ACTIVITY AND MANGANESE SUPEROXIDE DISMUTASE IN COMORBIDITY OF GASTROESOPHAGEAL REFLUX DISEASE AND AUTOIMMUNE THYROIDITIS IN STUDENT POPULATION

2020 ◽  
Vol 73 (12) ◽  
pp. 2644-2650
Author(s):  
Tamara M. Pasiieshvili ◽  
Natalia M. Zhelezniakova ◽  
Lyudmila M. Pasiyeshvili ◽  
Olga M. Kovalyova
Keyword(s):  
Antioxidant Activity ◽  
Superoxide Dismutase ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Autoimmune Thyroiditis ◽  
Reflux Disease ◽  
Manganese Superoxide Dismutase ◽  
Total Antioxidant Activity ◽  
Manganese Superoxide ◽  
Total Antioxidant

The aim: To determine the state of total antioxidant activity and the content of the mitochondrial enzyme – manganese superoxide dismutase in students with gastroesophageal reflux disease (GERD) and autoimmune thyroiditis (AIT) comorbidity. Materials and methods: 120 patients with GERD and AIT, 45 patients with GERD and 42 patients with AIT were examined. The patients involved in the study were students. The international standardized GerdQ questionnaire was used. Total antioxidant activity and manganese superoxide dismutase levels were determined. Results: The study showed that comorbidity of GERD and AIT was accompanied with a significant increase in the frequency and intensity of heartburn, sleep disorders and the use of additional medications to relieve symptoms. Patients with GERD and AIT had significantly lower total antioxidant activity than patients with isolated GERD and isolated AIT. At the same time, the manganese superoxide dismutase level was significantly higher in group with comorbidity than in patients with isolated diseases. Conclusions: The presence of concomitant AIT in patients with GERD among the student population contributes to some deviations in the clinical characteristics, inhibition of total antioxidant activity and activation of manganese superoxide dismutase.

scholarly journals Gastroesophageal reflux disease in residents of the Trans-Baikal Territory

2020 ◽  
Vol 101 (5) ◽  
pp. 661-668
Author(s):  
A A Zhilina ◽  
N V Lareva ◽  
E V Luzina
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Reflux Disease ◽  
Morphological Changes ◽  
Smoking Status ◽  
Erosive Esophagitis ◽  
Coffee Consumption ◽  
Esophageal Mucosa ◽  
Prevalence Of Obesity ◽  
Gerd Symptoms

Aim. To study the prevalence of gastroesophageal reflux disease (GERD) symptoms and lesions of the esophageal mucosa in residents of Zabaikalsky krai, taking into account ethnicity. Methods. The first stage: 371 residents of Zabaikalsky krai over 18 years old, were door-to-door interviewed by using the GERD questionnaire (GerdQ). The respondents with 8 or more points were classified as having GERD symptoms. Additionally, we collected passport data, smoking status, alcohol and coffee consumption, anthropometric data and social status. The second stage: we analyzed 2130 upper gastrointestinal (GI) endoscopy reports from Regional Clinical Hospital in Chita. Results. 48 (12.9%) of 371 respondents had GERD symptoms. 135 (36.4%) respondents were Buryats, and 236 (63.6%) were non-Buryats, with the latter more often had GerdQ total score of 8 or more [38 (16.1%) non-Buryats and 10 (7.4%) Buryats, p=0.009]. The average age of non-Buryats respondents with GERD symptoms was 53.417.47 years and exceeded that in the group without symptoms (46.219.2 years), p=0.035. The age of Buryats with and without GERD symptoms did not differ (42.6711.52 and 37.8915.54 years, respectively, р=0.087). The prevalence of obesity, smoking, alcohol and coffee consumption of respondents with and without GERD symptoms, both among Buryats and non-Buryats was the same. Of the 2130 patients who underwent endoscopy, 164 (7.8%) had morphological changes in the esophagus, 105 (4.9%) had erosive esophagitis (EE). Catarrhal and erosive changes in the esophagus were detected in 156 non-Buryats (91 men and 66 women) (7.7%), while EE was diagnosed in 97 (4.8%) patients. 6.5% (5 women and 3 men) Buryats had the esophagus pathology, which caused by erosion. It was found that in non-Buryats group EE develop more often in male respondents (p=0.0019). Only non-Buryats had catarrhal changes in the esophagus (37.8%, 59 people), p=0.0312. At the same time, the incidence of complicated disease course in groups with EE was the same (p=0.8934). Conclusion. About 13% of residents of Zabaikalsky krai have weekly symptoms of GERD, male of a non-Buryat ethnic group are more likely to develop erosive esophagitis than women; the incidence of complications of esophagitis is the same in Buryats and non-Buryats respondents groups.

Gastroesophageal Reflux Disease: A Gastroenterologist's Perspective

2011 ◽  
Vol 21 (3) ◽  
pp. 89-99
Author(s):  
Michael F. Vaezi
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Reflux Disease ◽  
Best Practice ◽  
Clinical Care ◽  
Diagnostic Testing ◽  
Diagnostic Tools ◽  
Swallowing Function ◽  
Atypical Symptoms

Gastroesophageal reflux disease (GERD) is a commonly diagnosed condition often associated with the typical symptoms of heartburn and regurgitation, although it may present with atypical symptoms such as chest pain, hoarseness, chronic cough, and asthma. In most cases, the patient's reduced quality of life drives clinical care and diagnostic testing. Because of its widespread impact on voice and swallowing function as well as its social implications, it is important that speech-language pathologists (SLPs) understand the nature of GERD and its consequences. The purpose of this article is to summarize the nature of GERD and GERD-related complications such as GERD-related peptic stricture, Barrett's esophagus and adenocarcinoma, and laryngeal manifestations of GERD from a gastroenterologist's perspective. It is critical that SLPs who work with a multidisciplinary team understand terminology, diagnostic tools, and treatment to ensure best practice.

Laparoscopic antireflux surgery with routine hiatoplasty in the treatment of gastroesophageal reflux disease

2001 ◽  
Vol 120 (5) ◽  
pp. A480-A480
Author(s):  
F GRANDERATH ◽  
U SCHWEIGER ◽  
T KAMOLZ ◽  
T BAMMER ◽  
M PASIUT ◽  
...  
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Reflux Disease ◽  
Antireflux Surgery ◽  
Laparoscopic Antireflux Surgery
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