Prevalence of Nutrition- Impact Symptoms at Different Disease Stages among Paediatric Cancer Patients Undergoing Chemotherapy at Moi Teaching and Referral Hospital, Eldoret, Kenya

<p>Malnutrition incidence among patients with cancer ranges from 30% - 80% globally. Cancer is a major cause of death in Kenya after cardiovascular and infectious diseases. This research assessed the relationship between nutritional status and quality of life (QoL) of the 52 paediatric cancer patients undergoing chemotherapy at Moi Teaching and Referral Hospital (MTRH) Eldoret, Kenya. A cross-sectional analytical design was applied and the researcher administered a questionnaire and Nutritional Risk Screening (NRS-2002) instruments were used for data collection. The statistical package for social sciences (SPSS) version 21 was used to analyse the data descriptively. The findings revealed that nutrition impact symptoms were more pronounced in the second and third stages of cancer where most of the respondents experienced vomiting (94.3%), decreased appetite (80.8%), and diarrhoea (69.23%). The use of the Nutrition Impact Symptom (NIS) checklist in the paediatric oncology clinic/ward triggers more therapeutic interventions. The awareness for NIS will likely evoke more research in assessment, impact, and treatment.</p>

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High neutrophil to lymphocytes ratio is associated with nutritional risk in hospitalised, unselected cancer patients: a cross-sectional study

Scientific Reports ◽

10.1038/s41598-021-96586-z ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Jéssika M Siqueira ◽

Jéssika D P Soares ◽

Thaís C Borges ◽

Tatyanne L N Gomes ◽

Gustavo D Pimentel

Keyword(s):

Logistic Regression ◽

Cancer Patients ◽

Systemic Inflammation ◽

Roc Curve ◽

Cross Sectional Study ◽

Nutritional Risk ◽

Sectional Study ◽

Cross Sectional ◽

Cut Point ◽

Nrs 2002

AbstractCancer patients possess metabolic and pathophysiological changes and an inflammatory environment that leads to malnutrition. This study aimed to (i) determine whether there is an association between neutrophil-to-lymphocyte ratio (NLR) and nutritional risk, and (ii) identify the cut-off value of NLR that best predicts malnutrition by screening for nutritional risk (NRS 2002). This cross-sectional study included 119 patients with unselected cancer undergoing chemotherapy and/or surgery. The NRS 2002 was applied within 24 h of hospitalisation to determine the nutritional risk. Systemic inflammation was assessed by blood collection, and data on C-reactive protein (CRP), neutrophils, and lymphocytes were collected for later calculation of NLR. A receiver operating characteristic (ROC) curve was used to identify the best cut-point for NLR value that predicted nutritional risk. Differences between the groups were tested using the Student’s t-, Mann–Whitney U and Chi-Square tests. Logistic regression analyses were performed to assess the association between NLR and nutritional risk. The ROC curve showed the best cut-point for predicting nutritional risk was NLR > 5.0 (sensitivity, 60.9%; specificity, 76.4%). The NLR ≥ 5.0 group had a higher prevalence of nutritional risk than the NLR < 5.0 group (NLR ≥ 5.0: 73.6% vs. NLR < 5.0: 37.9%, p = 0.001). The NLR group ≥ 5.0 showed higher values of CRP and NLR than the NLR < 5.0 group. In addition, patients with NLR ≥ 5.0 also had higher NRS 2002 values when compared to the NLR < 5.0 group (NLR ≥ 5.0: 3.0 ± 1.1 vs. NLR < 5.0: 2.3 ± 1.2, p = 0.0004). Logistic regression revealed an association between NRS and NLR values. In hospitalised unselected cancer patients, systemic inflammation measured by NLR was associated with nutritional risk. Therefore, we highlight the importance of measuring the NLR in clinical practice, with the aim to detect nutritional risk.

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Standardized Phase Angle as a Prognostic and Nutritional Status Tool for Pancreatic Cancer Patients Undergoing Pancreaticoduodenectomy: A Cross-sectional Study (P12-025-19)

Current Developments in Nutrition ◽

10.1093/cdn/nzz035.p12-025-19 ◽

2019 ◽

Vol 3 (Supplement_1) ◽

Author(s):

Wei Chen ◽

Shengnan Zhou

Keyword(s):

Pancreatic Cancer ◽

Postoperative Complications ◽

Nutritional Status ◽

Cancer Patients ◽

Phase Angle ◽

Cross Sectional Study ◽

Nutritional Risk ◽

Sectional Study ◽

Cross Sectional ◽

Nrs 2002

Abstract Objectives This study investigated the use of standardized phase angle (SPA), determined by bioelectrical impedance analysis (BIA), as a nutrition status tool and prognostic factor for complications associated with pancreaticoduodenectomy (PD) in pancreatic cancer patients. Methods A cross-sectional study was conducted with 49 participants. All participants were assessed for nutritional risk and nutritional status using Nutritional Risk Screening 2002 (NRS-2002), Subjective Global Assessment (SGA) tools, Global Leadership Initiative on Malnutrition (GLIM) tool and BIA. The Clavien-Dindo classification method for surgical complications was used to identify and classify postoperative complications. Independent-samples T-tests, chi-square tests and Spearman correlation analyses were used to evaluate the association between SPA, nutrition and postoperative complications. Results A total of 49 patients were enrolled, and 20 patients (40%) had postoperative complications. The SPA value for the nourished group was significantly higher than the SPA value for the malnourished group (P = 0.021, 0.019, 0.023). Patients who were below the SPA cut-off values (−1.015, −1.065, and −0.69) were more likely to have postoperative complications (P = 0.009), whereas NRS-2002, SGA, and GLIM scores were not associated with postoperative complications. The SPA value of the group with complications was significantly lower than that of the group without complications (P = 0.004). The SPA threshold value for predicting postoperative complications in pancreatic cancer was −1.095 (AUC 0.737; 95% CI, 0.59, 0.88; P = 0.005). Conclusions The SPA is a prognostic indicator of postoperative complications in pancreatic cancer patients undergoing PD and is an effective tool for assessing nutritional status in pancreatic cancer patients. Funding Sources none. Supporting Tables, Images and/or Graphs

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Relationship between the depression levels and nutritional statuses of advanced stage cancer patients

Palliative & Supportive Care ◽

10.1017/s1478951521001516 ◽

2021 ◽

pp. 1-8

Author(s):

Dilek Yildirim

Keyword(s):

Cancer Patients ◽

Beck Depression Inventory ◽

Severe Depression ◽

Strong Relationship ◽

Nutritional Risk ◽

Advanced Stage ◽

Cross Sectional ◽

Nrs 2002 ◽

The Mean ◽

Advanced Stage Cancer

Abstract Objective This study aimed to determine the depression and nutritional statuses of advanced stage cancer patients and investigate the relationship between depression and malnutrition. Method The descriptive, cross-sectional, and correlational study was conducted with 245 patients with advanced cancer. The data were collected by using an Information Form, the Visual Analog Scale, the NRS-2002-Nutritional Risk Score, and the Beck Depression Inventory. Results The mean NRS-2002 score of the patients was 2.22, and when the cutoff value was accepted as 3, it was determined that 39.2% of the patients had malnutrition. The mean Beck Depression Inventory score of the patients was 35.06, and they were found to experience severe depression. There was a positive and significant relationship between the NRS-2002 scores and the Beck Depression Inventory scores (r = 0.409; p < 0.001). Significance of results These results showed that there was a strong relationship between the depression and malnutrition levels of advanced stage cancer patients. Deterioration in the nutritional status of the advanced stage cancer patients was associated with a significant worsening effect in terms of depression and pain.

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Evaluation of Nutritional Risk and Prevalence of Obesity in Patients with Covid-19 in A Reference Hospital in Salvador, Bahia, Brazil: A Cross-Sectional Study

International Journal of Nutrology ◽

10.1055/s-0041-1728680 ◽

2021 ◽

Vol 14 (01) ◽

pp. 011-015

Author(s):

Rodrigo Fernandes Weyll Pimentel ◽

Gilson Cruz de Moraes ◽

Shalla Gomes Cavalcanti Barcelos ◽

Pedro Carlos Muniz de Figueiredo ◽

Magno Conceição Das Merces

Keyword(s):

Cross Sectional Study ◽

Nutritional Risk ◽

Sectional Study ◽

Cross Sectional ◽

High Prevalence ◽

Reference Hospital ◽

Prevalence Of Obesity ◽

Nrs 2002 ◽

Study Type ◽

Nutritional Risk Screening

Abstract Introduction The Coronavirus has spread to almost every country in the world, causing the coronavirus disease (COVID-19). The coronavirus stands out among the other infections especially by it's high contagious power and important effects on the respiratory system. The COVID-19 has differents ways of presentation and these are influenced by the patient's previous nutricional status, correlated with the patient's lifestyle and comorbities. Objective this survey seeks to analyze the nutritional status and the prevalence of obesity in patients hospitalized with SARS-CoV-2. Methods: this is a descriptive, prospective and cross-sectional study type, which 41 patients affected by COVID-19 were interviewed. Patient's weight and height were used to assess the BMI, and nutritional risk assessment was performed using the Nutritional Risk Screening tool (NRS 2002). For the analysis, Absolute (AF) and Relative Frequency (RF), the mean and the standard deviation were calculated. Results It was observerd that 78% of the participants had a high nutritional risk, while only 22% had a low nutritional risk. Besides that, 34% showed overweight and 41.4% showed obesity. Conclusion the existence of a high prevalence of increased nutritional risk was evidenced, in addition to the high frequency of overweight in patients affected by SARS-CoV-2.

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The Frequency of Malnutrition in Patients with Type 2 Diabetes

Medeniyet Medical Journal ◽

10.5222/mmj.2021.44270 ◽

2021 ◽

Author(s):

Miraç Vural Keskinler ◽

Güneş Feyizoğlu ◽

Kübra Yıldız ◽

Aytekin Oğuz

Keyword(s):

Type 2 Diabetes ◽

Outpatient Clinic ◽

High Body Mass Index ◽

Cross Sectional Study ◽

University Hospital ◽

Nutritional Risk ◽

Cross Sectional ◽

Significant Difference ◽

Nrs 2002

Objective: Obesity is one of the most common comorbidities of diabetes mellitus (DM) whose frequency is rapidly increasing nowadays. Although obesity caused by excessive and unbalanced nutrition often accompanies diabetes; malnutrition is another complication of diabetes. This study was conducted to investigate the frequency of malnutrition in individuals with diabetes. Method: This study is a cross-sectional study. The patients with type 2 diabetes followed up in the diabetes outpatient clinic of a university hospital between February and March 2018 were included in the study. Anthropometric measurements of the patients and “Nutritional Risk Screening-2002” (NRS-2002) scores were recorded. Results: A total of 222 (F: 132 59.4%) patients were included in the study. When two groups with higher NRS (≥3) and lower NRS (<3) scores less than 3 were compared, any significant difference was not detected between two groups in terms of age, waist circumference and HbA1c values. Only BMI was found to be lower in the group with malnutrition risk (p: 0.030). When the patients were evaluated in terms of diabetes treatments and risk of malnutrition, any significant intergroup difference was not found (p: 0.847). Conclusion: It was found that there is a risk of malnutrition in one of every seven diabetics with a high body mass index who were being followed up in the diabetes outpatient clinic.

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Pattern of chemotherapy-related adverse effects among adult cancer patients treated at Gondar University Referral Hospital, Ethiopia: a cross-sectional study

Drug Healthcare and Patient Safety ◽

10.2147/dhps.s116924 ◽

2016 ◽

Vol Volume 8 ◽

pp. 83-90 ◽

Cited By ~ 7

Author(s):

Sewunet Admasu Belachew ◽

Daniel Asfaw Erku ◽

Abebe Basazn Mekuria ◽

Begashaw Melaku Gebresillassie

Keyword(s):

Adverse Effects ◽

Cancer Patients ◽

Cross Sectional Study ◽

Referral Hospital ◽

Sectional Study ◽

Cross Sectional

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Nutritional Profile of Patients with Colorretal Cancer Candidates for Big Surgery (P05-035-19)

Current Developments in Nutrition ◽

10.1093/cdn/nzz030.p05-035-19 ◽

2019 ◽

Vol 3 (Supplement_1) ◽

Author(s):

Ana Paula Rocha Trotte ◽

Rosana Oliveira Macedo ◽

Thaiza Fragoso Nunes ◽

Danielly Rodrigues Wassita da Rocha ◽

Maria Eliza De Gouvêa Marti Ferrão

Keyword(s):

Colorectal Cancer ◽

Weight Loss ◽

Nutritional Status ◽

Nutritional Assessment ◽

Nutritional Risk ◽

Cross Sectional ◽

Nutritional Profile ◽

Funding Sources ◽

Nrs 2002

Abstract Objectives To identify the nutritional profile of adult and elderly patients with colorectal cancer admitted to a Proctology ward for large elective surgeries. Methods A cross-sectional and retrospective study was performed with 31 patients of both genders, aged 39 to 77 years with colorectal cancer. The nutritional screening parameters used were the percentage of weight loss and Nutrition Risck Screening (NRS 2002). The data (percentage of weight loss and NRS 2002) were collected through a nutritional assessment form completed in the care routine, applied within 72 hours after the patient's hospitalization. Results The study included 13 adults (41.9%) and 18 elderly (58.1%). The evaluation of the percentage of weight loss showed that 7 patients (22.5%) had weight loss greater than 15% in a period of less than or equal to 6 months. In the nutritional risk assessment based on the NRS 2002, we observed that 9 patients (29%) scored 2, while 22 patients (71%) achieved a score equal to or greater than 3. Conclusions The nutritional profile of the evaluated patients showed a considerable prevalence of malnutrition, considering a weight loss of more than 15% in a period of 6 months, which is associated to a decrease in survival in patients with cancer, and is a very relevant data to help in the classification of nutritional status. The classification by the NRS 2002, showed a high prevalence of patients at nutritional or malnourished risk. Variation in the classification of nutritional status using several parameters reinforces the need for them to be used in a complementary way. Funding Sources Hospital Federal dos Servidores do Estado, Ministerio da Saude.

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