Gastrointestinal carriage of Klebsiella pneumoniae is a risk factor of subsequent hospital acquired infection

2017 ◽  
Vol 1 (12) ◽  
pp. 47-47
Author(s):  
Xiaohua Qin ◽  
Fupin Hu
Keyword(s):  
Risk Factor ◽  
Klebsiella Pneumoniae ◽  
Hospital Acquired Infection ◽  
Hospital Acquired

scholarly journals “Invasive Klebsiella Pneumoniae Syndrome in Qatar”

2021 ◽  
Author(s):  
Muhammad Jamshaid ◽  
Aamir Shahzad ◽  
Huma Munir ◽  
Muhammad Tayyab ◽  
Abdul Aziz Zafar. ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
High Risk ◽  
Klebsiella Pneumoniae ◽  
Morbidity And Mortality ◽  
Metastatic Spread ◽  
Hospital Acquired Infection ◽  
High Risk Patients ◽  
Risk Patients ◽  
Hospital Acquired

Klebsiella pneumoniae can cause community-acquired and hospital-acquired infection. It increases morbidity and mortality in high-risk patients. We present a case of invasive Klebsiella pneumoniae in poorly controlled diabetes mellitus, who ended up having a metastatic spread of Klebsiella pneumoniae involving the liver, lungs, kidneys, brain, and muscle.

scholarly journals Comparison of the Value of SOFA and Pitt Bacteremia Scores in the Prognostic Evaluation of Patients With Hospital-acquired Klebsiella Pneumoniae Bloodstream Infection

2021 ◽  
Author(s):  
Jun Guo ◽  
Shuaihua Fan ◽  
Jinlan Lin ◽  
Sheng Wu
Keyword(s):  
Klebsiella Pneumoniae ◽  
Bloodstream Infection ◽  
Sofa Score ◽  
Tertiary Hospital ◽  
Klebsiella Pneumonia ◽  
Survival Group ◽  
Hospital Acquired Infection ◽  
Prognostic Evaluation ◽  
The Difference ◽  
Hospital Acquired

Abstract This clinical research studied the value of SOFA score and Pitt bacteremia score in the prognosis assessment of patients with hospital-acquired Klebsiella pneumonia bloodstream infection. We conducted a retrospective analysis of 40 patients with hospital-acquired Klebsiella pneumoniae bloodstream infection in a tertiary hospital from January 2016 to December 2020. For these patients, the SOFA score and Pitt bacteremia score were used to evaluate the prognosis. Logistic regression was performed with the known prognosis results to obtain the best cut-off value, sensitivity, and specificity. Pitt bacteremia score [3 (3-4) points to 6 (5.5-7) points] and SOFA score [7 (6-10) points to 17 (13-17.5) points] in the survival group were lower than those in the death group (P<0.05). The SOFA score predicts the death of hospital-acquired Klebsiella pneumoniae bloodstream infection patients with a sensitivity of 80%, a specificity of 84%, and the area under curve(AUC) of SOFA score is 0.8960 (95% CI 0.7951-0.9969); Pitt bacteremia score predicts the hospital-acquired Klebsiella pneumoniae blood infection with a sensitivity of 86.67%, a specificity of 80%, and AUC of Pitt bacteremia score is 0.9413 (95% CI 0.8700- 1.000). Both the SOFA score and the Pitt bacteremia score have predictive value for the prognosis of patients with HAI (hospital acquired infection) Klebsiella pneumonia blood infection. However, the difference shows that the SOFA score has obvious accuracy and specificity in the prognosis of patients with HAI Klebsiella pneumoniae bloodstream infection, it is better than the Pitt bacteremia score and has greater application prospects in prognostic evaluation.

scholarly journals Pola bakteri aerob yang berpotensi menyebabkan infeksi nosokomial di Instalasi Gawat Darurayt RSAD Robert Wolter Mongisidi Manado

2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Sitti N. Gobel ◽  
Fredine E.S. Rares ◽  
Heriyannis Homenta
Keyword(s):  
Escherichia Coli ◽  
Klebsiella Pneumoniae ◽  
Emergency Room ◽  
Medical Equipment ◽  
Ambient Air ◽  
Aerobic Bacteria ◽  
Bacillus Sp ◽  
Enterobacter Agglomerans ◽  
Hospital Acquired Infection ◽  
Hospital Acquired

Abstract: Nosocomial infection or Hospital Acquired infection (HAI) is caused by bacteria, parasites or viruses in hospitals and occurs after ≥48 hours of hospital admission. Emergency room is te starting place procedures and or medical measures so that the room IGD became one of the places that produces a lot of waste of medical procedures performed and as one of the places most likely to transmit the infection. This study was aimed to determine the sources and patterns of aerobic bacteria that could potentially cause nosocomial infections: in the walls, floors, medical equipment, and ambient air of Emergency Room Robert Wolter Mongisidi Hospital, Manado. This was a descriptive prospective study with a cross sectional design. Samples were bacteria in the walls, floors, medical equipment, and the ambient air of the room IGD in the emergency room, Robert Wolter Mongisidi Hospital, Manado. The results showed that of the 29 samples taken, one sample did not contain any bacteria. There were eight types of bacteria found: Bacillus sp (33%), Staphylococcus sp (27%) Enterobacter agglomerans (13%), Escherichia coli (10%), Streptococcus sp (10%), Serratia marcescens (3%), Neisseria sp (2%) and Klebsiella pneumoniae (2%). Conclusion: The most common bacteria was Bacillus sp.Keywords: IGD, nosocomial infections, patterns of aerobic bacteria Abstrak: Infeksi nosokomial atau Hospital Acquired infection (HAI) merupakan infeksi yang disebabkan oleh bakteri, parasit atau virus di rumah sakit, terjadi ≥ 48 jam sejak masuk rumah sakit. Ruangan IGD merupakan tempat awal pasien mendapatkan prosedur dan atau tindakan medis sehingga ruangan IGD menjadi salah satu tempat yang banyak menghasilkan limbah hasil prosedur dan tindakan medis yang dilakukan serta salah satu tempat yang paling mungkin menularkan infeksi. Penelitian ini bertujuan untuk mengetahui sumber dan pola bakteri aerob yang berpotensi menyebabkan infeksi nosokomial: di dinding, lantai, peralatan medis, dan udara di ruang IGD pada ruang gawat darurat medik RSAD Robert Wolter Mongisidi Manado. Jenis penelitian ialah deskriptif prospektif dengan desain otong lintang. Sampel penelitian ialah bakteri pada dinding, lantai, peralatan medis, dan udara di ruang gawat darura tmedik RSAD Robert Wolter Mongisidi Manado. Hasil penelitian memperlihatkan dari 29 sampel yang diambil 1 sampel tidak terdapat bakteri. Terdapat 8 jenis bakteri yang ditemukan yaitu: Bacillus sp (33%), Staphylococcus sp (27%), Enterobacter agglomerans (13%), Escherichia coli (10%), Streptococcus sp (10%), Serratia marcescens (3%), Neisseria sp (2%) dan Klebsiella Pneumoniae (2%). Simpulan: Bakteri yang paling banyak ditemukan ialah Bacillus sp. Kata kunci: IGD, infeksi nosokomial, pola bakteri aerob

scholarly journals “Invasive Klebsiella Pneumoniae Syndrome in Qatar”

2021 ◽  
Author(s):  
Muhammad Jamshaid ◽  
Aamir Shahzad ◽  
Huma Munir ◽  
Muhammad Tayyab ◽  
Abdul Aziz Zafar. ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
High Risk ◽  
Klebsiella Pneumoniae ◽  
Morbidity And Mortality ◽  
Metastatic Spread ◽  
Hospital Acquired Infection ◽  
High Risk Patients ◽  
Risk Patients ◽  
Hospital Acquired

Klebsiella pneumoniae can cause community-acquired and hospital-acquired infection. It increases morbidity and mortality in high-risk patients. We present a case of invasive Klebsiella pneumoniae in poorly controlled diabetes mellitus, who ended up having a metastatic spread of Klebsiella pneumoniae involving the liver, lungs, kidneys, brain, and muscle.

scholarly journals Characteristics of Klebsiella Pneumoniae ST4 Coharboring qnrB1, aac-Ib-cr, CTX-M-15 and SHV 11 in a Tunisian Hospital

2020 ◽  
Author(s):  
MARIEM Nasri Yaiche ◽  
Ikbel Denden Rafraf ◽  
qinglan guo ◽  
Maha Mastouri ◽  
Mahjoub Aouni ◽  
...  
Keyword(s):  
Klebsiella Pneumoniae ◽  
Susceptibility Testing ◽  
Direct Sequencing ◽  
Therapeutic Process ◽  
Diffusion Method ◽  
Disc Diffusion Method ◽  
Hospital Acquired Infection ◽  
Pcr Products ◽  
Hospital Acquired ◽  
Positive Results

Abstract Background: Multiresistant Klebsiella pneumoniae are predominant cause of hospital acquired infection. This work describes the molecular epidemiology of these isolates in Tunisian Hospital.Methods: Between October 2010 and June 2013, 50 non-duplicated clinical K.pneumoniae were selected on the basis of nalidixic acid (NA) resistance and were characterized. Isolates were identified using APi 20E system. Susceptibility testing was determined using the disc diffusion method and the microdilution technique to determine the MIC of ciprofloxacin.PMQR and ESBL genes were detected by PCR and positive results were confirmed by direct sequencing of PCR products. Multilocus sequence typing (MLST) was performed to determine the genetic relationship among isolates. Conjugation and transformation were done to know if PMQR and ESBL were carried with one or two plasmids.Results: A total of 20 PMQR harboring K.pneumoniae representing 40% of all NA resistant isolates were characterized. Among PMQR positive K.pneumoniae 13 were resistant to amoxicilline, amoxicilline/clavulanic acid, ticarcilline, piperacilline, cefaloridine, cefotaxime (CTX) and ceftazidime. The rate of resistance to gentamicine, tobramicine and amikacine were 85%, 95% and 25% respectively.Out of 20 K.pneumoniae (60%) were qnr positive (1 qnrA6 and 11 qnrB1) and (60%) were aac-Ib-cr positive. 33.3% coharbored the aac-Ib-cr and qnrB1 determinants. Out of all PMQR positive strains, 65% harbored ctx-M-15 gene. It was associated to shv11 in three cases and tem1 in two cases. The predominant types were ST4 (35%) and ST15 (20%). ST 101(15%) and ST 147 (10%) come in second order. one case of each ST14,ST86,ST336 and ST307 were also observed. qnrB1, aac-Ib-cr, Ctx-m-15 can be carried with more than one plasmid in the same bacteria.Conclusion: The co-existing of different genes conferring resistance among the same and different family of antibiotics is a big threat to patient because it limits the therapeutic process. This phenomonen is a problem of concern that needs to improve the resistance surveillance of multi gene carrying K pneumoniae.

Isolation of post operative hospital acquired infections in a private hospital of Bangladesh and identification of clonal relatedness of E. coli by using Pulse filed gel electrophoresis

2012 ◽  
Vol 6 (2) ◽  
pp. 7-10
Author(s):  
Mohammad Murshed ◽  
Sabeena Shahnaz ◽  
Md. Abdul Malek
Keyword(s):  
Private Hospital ◽  
Isolation And Identification ◽  
College Hospital ◽  
Hospital Acquired Infection ◽  
E Coli ◽  
Hospital Acquired Infections ◽  
Medical College ◽  
Clonal Relatedness ◽  
Hospital Acquired ◽  
Dressing Materials

Isolation and identification of post operative hospital acquired infection was carried out from July 2008 to December 2008 in Holy Family Red Crescent Medical College Hospital (private hospital). The major pathogen of wound infection was E. coli. A total; of 120 samples were collected from the surrounding environment of post operative room like floor, bed sheets, instruments, dressing materials, catheter, nasogastric and endotracheal tube. E. coli (40%) was the predominant organism followed by S. aureus (24%). DNA fingerprinting analysis using pulsed field gel electreopheresis of XbaI restriction digested genomic DNA showed that clonal relatedness between the two clinical nd environmental isolates were 100%.DOI: http://dx.doi.org/10.3329/bjmm.v6i2.19369 Bangladesh J Med Microbiol 2012; 06(02): 7-10

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