scholarly journals Applicability of Magnetic Resonance Imaging for Early Diagnosis of Common Peroneal Neuropathy

The Nerve ◽  
2021 ◽  
Vol 7 (2) ◽  
pp. 36-40
Author(s):  
Gwang Yoon Choi ◽  
Jinseo Yang ◽  
Yongjun Cho ◽  
Hyukjai Choi ◽  
Jinpyeong Jeon ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Early Diagnosis ◽  
Muscle Atrophy ◽  
Early Stage ◽  
Acute Onset ◽  
Resonance Imaging ◽  
Diagnostic Modality ◽  
Peroneal Neuropathy ◽  
Onset Group

Objective: This study aimed to assess the clinical applicability of magnetic resonance imaging (MRI) for the early diagnosis of common peroneal neuropathy (CPNe).Methods: Over three years, the authors have treated 58 patients with CPNe. All patients had clinical or neurophysiological confirmation of CPNe. Among them, 35 (60%) patients underwent axial knee MRI with a 1.5-Tesla scanner. These 35 patients were selected for study and were classified into three groups according to the time of examination after the occurrence of dropped foot―acute, subacute, and chronic onset groups. According to muscle appearances (normal, edematous change, and atrophy), we diagnosed them with CPNe, except for those with normal morphology. We evaluated the applicability of MRI in the diagnosis of CPNe compared to that of electromyography (EMG).Results: The 18, 11, and six cases were included in the acute, subacute, and chronic onset groups, respectively. In the acute onset group, three cases had normal muscle appearance, while 15 cases had edematous changes in the affected muscles. In the subacute onset group, eight cases had edematous changes, while three cases showed muscle atrophy. In the chronic onset group, six cases had muscle atrophy. CPNe could be diagnosed using MRI in about 91% (32/35) of all the cases. Excluding the chronologically chronic stage, diagnosis rate was approximately 89%(26/29) of all the cases. However, only in 27 cases (77%) denervation potentials were presented on EMG.Conclusion: According to our results, MRI is a helpful diagnostic modality, especially in the early stage of CPNe, and may lead to proper management.

scholarly journals Sialic acid-engineered mesoporous polydopamine dual loaded with ferritin gene and SPIO for achieving endogenous and exogenous synergistic T2-weighted magnetic resonance imaging of HCC

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Kai Fan ◽  
Chengying Lu ◽  
Gaofeng Shu ◽  
Xiu-Ling Lv ◽  
Enqi Qiao ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Sialic Acid ◽  
Magnetic Resonance ◽  
Early Diagnosis ◽  
Early Stage ◽  
In Vivo Studies ◽  
Resonance Imaging ◽  
Ferritin Gene ◽  
T2 Weighted Images

Abstract Background Hepatocellular carcinoma (HCC) is a common malignant tumor with poor prognosis. Magnetic resonance imaging (MRI) is one of the most effective imaging methods for the early diagnosis of HCC. However, the current MR contrast agents are still facing challenges in the early diagnosis of HCC due to their relatively low sensitivity and biosafety. Thus, the development of effective MR agents is highly needed for the early diagnosis of HCC. Results Herein, we fabricated an HCC-targeted nanocomplexes containing SPIO-loaded mesoporous polydopamine (MPDA@SPIO), sialic acid (SA)-modified polyethyleneimine (SA-PEI), and alpha-fetoprotein regulated ferritin gene (AFP-Fth) which was developed for the early diagnosis of HCC. It was found that the prepared nanocomplexes (MPDA@SPIO/SA-PEI/AFP-Fth) has an excellent biocompatibility towards the liver cells. In vivo and in vivo studies revealed that the transfection of AFP-Fth gene in hepatic cells significantly upregulated the expression level of ferritin, thereby resulting in an enhanced contrast on T2-weighted images via the formed endogenous MR contrast. Conclusions The results suggested that MPDA@SPIO/SA-PEI/AFP-Fth had a superior ability to enhance the MR contrast of T2-weighted images of tumor region than the other preparations, which was due to its HCC-targeted ability and the combined T2 contrast effect of endogenous ferritin and exogenous SPIO. Our study proved that MPDA@SPIO/SA-PEI/AFP-Fth nanocomplexes could be used as an effective MR contrast agent to detect HCC in the early stage.

scholarly journals MAGNETIC RESONANCE IMAGING IN THE DIAGNOSIS OF JUVENILE IDIOPATHIC ARTHRITIS

2015 ◽  
Vol 14 (1) ◽  
pp. 110-119
Author(s):  
A. K. Traudt ◽  
V. D. Zavadovskaya ◽  
T. V. Zhogina ◽  
Ye. I. Fedorova
Keyword(s):  
Magnetic Resonance Imaging ◽  
Juvenile Idiopathic Arthritis ◽  
Magnetic Resonance ◽  
Early Diagnosis ◽  
Structural Changes ◽  
Early Stage ◽  
Response To Treatment ◽  
X Rays ◽  
Loss Of Function ◽  
Resonance Imaging

Juvenile idiopathic arthritis (JIA) are a group of socially significant diseases of childhood because of the high prevalence of a chronic nature, as well as a large percentage of early disability. JIA is a collection of diseases that have different start, course and outcome, as well as various etiologies, which emphasizes the difficulties in the diagnosis process in children. When this disease is progressive in nature, leads to loss of function of the musculoskeletal system, severe disability at an early age and, therefore, needs early diagnosis and adequate therapy appointment.Significant role in identifying pathology osteoarticular system belongs radiological methods and routine radiography remains the most widely used technique included in the classification criteria of the majority of rheumatic diseases. However, it is well known that secondary structural changes in the bones precedes roentgen period, and therefore the X-rays can not be regarded as a method of early diagnosis with articular syndrome. Widely introduced in recent years, magnetic resonance imaging (MRI) has more say in the assessment of capabilities of the joints, as in addition to assessment of bone allows quantitatively and qualitatively assess changes in the synovial membrane, articular cartilage, the presence and severity of inflammatory changes in the periarticular soft tissue and bone tissue. The data obtained using MRI may be used for diagnosis, prognosis, and monitoring response to treatment, including early stage disease.Nevertheless, despite the obvious opportunities MRI, this technique is not widely used, including the lack of clear diagnostic criteria for the disease, the lack of centralized research validated, standardized protocols for conducting MRI studies of children with articular syndrome. Thus, research is warranted to address a number of clinical and diagnostic aspects in JIA, in particular the development of the scoring system assessing the severity and progression of the disease.

Multifunctional targeted nanoprobe with high NIR-II PAI/MRI performance for precise theranostics of orthotopic early-stage hepatocellular carcinoma

2021 ◽  
Author(s):  
Linyun He ◽  
Yachao Zhang ◽  
Jiangbo Chen ◽  
Gongyuan Liu ◽  
Jingyi Zhu ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Hepatocellular Carcinoma ◽  
Magnetic Resonance ◽  
Early Diagnosis ◽  
Effective Treatment ◽  
Near Infrared ◽  
Photoacoustic Imaging ◽  
Early Stage ◽  
Resonance Imaging ◽  
Infrared Window

Early diagnosis and effective treatment of hepatocellular carcinoma (HCC) is quite critical for improving patients’ prognosis. The combination of second near-infrared window photoacoustic imaging (NIR-II PAI) and T2-magnetic resonance imaging...

scholarly journals The value of contrast-enhanced FLAIR magnetic resonance imaging in detecting meningeal abnormalities in suspected cases of meningitis compared to conventional contrast-enhanced T1WI sequences

2020 ◽  
Vol 51 (1) ◽  
Author(s):  
Wael Hamza Kamr ◽  
Mohamed Gaber Eissawy ◽  
Amr Saadawy
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Early Diagnosis ◽  
Diagnosis And Treatment ◽  
Effective Management ◽  
Resonance Imaging ◽  
Flair Sequence ◽  
Csf Analysis ◽  
Contrast Enhanced ◽  
Magnetic Resonance Imaging Mri

Abstract Background Early diagnosis of meningitis with magnetic resonance imaging (MRI) would be useful for appropriate and effective management, decrease morbidity and mortality, and provide better diagnosis and treatment. The objective of the current study is to compare the accuracy of contrast-enhanced FLAIR (CE-FLAIR) and contrast-enhanced T1WI (CE-T1WI) in the detection of meningeal abnormalities in suspected cases of meningitis. Results Out of 45 patients, 37 patients were confirmed to have meningitis on CSF analysis. Out of the 37 patients, 34 patients were positive on CE-FLAIR sequence and 27 were positive on CE-T1WI. The sensitivity of CE-FLAIR sequence was 91.9% and specificity 100%, while the sensitivity of CE-T1WI sequence was 73% and specificity 100%. Conclusion CE-FLAIR is more sensitive than CE-T1WI in diagnosis of meningitis. It is recommended to be used in any cases with clinically suspected meningitis.

Early-stage cervical cancer: Tumor delineation by magnetic resonance imaging and ultrasound — A European multicenter trial

2013 ◽  
Vol 128 (3) ◽  
pp. 449-453 ◽  
Author(s):  
Elisabeth Epstein ◽  
Antonia Testa ◽  
Adrius Gaurilcikas ◽  
Alessia Di Legge ◽  
Liveke Ameye ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Cervical Cancer ◽  
Magnetic Resonance ◽  
Early Stage ◽  
Multicenter Trial ◽  
Resonance Imaging ◽  
Tumor Delineation ◽  
Early Stage Cervical Cancer ◽  
Cancer Tumor

Early diagnosis of cardiac sarcoidosis using magnetic resonance imaging

2008 ◽  
Vol 125 (1) ◽  
pp. e4-e5 ◽  
Author(s):  
Faizel Osman ◽  
Aboo Foundon ◽  
Paco Leyva ◽  
Michael Pitt ◽  
R. Gordon Murray
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Early Diagnosis ◽  
Cardiac Sarcoidosis ◽  
Resonance Imaging

Magnetic resonance imaging of denervation-induced muscle atrophy: Effects of clenbuterol in the rat

2001 ◽  
Vol 24 (12) ◽  
pp. 1647-1658 ◽  
Author(s):  
Michael D. Cockman ◽  
Melissa B. Jones ◽  
Marla C. Prenger ◽  
Russell J. Sheldon
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Muscle Atrophy ◽  
Resonance Imaging

Early diagnosis of spondyloarthritis and gonarthritis with the magnetic resonance imaging

2020 ◽  
pp. 66-77
Author(s):  
Gulnara Abdulkhakovna Kantyukova ◽  
Nataliya Ivanovna Valieva ◽  
Igor Aleksandrovich Kutuzov ◽  
Artem Andreevich Bogachev ◽  
Yuriy Olegovich Novikov
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Early Diagnosis ◽  
Knee Joint ◽  
Dynamic Control ◽  
Significant Loss ◽  
Lumbar Region ◽  
Resonance Imaging ◽  
Aseptic Inflammation ◽  
Longitudinal Splitting

Introduction. Musculoskeletal pain (MSP) — has now assumed the character of a non-infectious epidemic and ranks second among the causes of disability, leading to a significant loss of productivity among the working-age population in all industrialized countries. Spondyloarthrosis of the lumbar region and gonarthrosis are the main diseases that doctors face at outpatient appointments. The pathogenesis of the disease develops according to one scenario, accompanied by aseptic inflammation, involvement of the muscular and ligamentous apparatus in the process, leading to the formation of dissimilar locomotor disorders, antinociceptive insufficiency, peripheral and central sensitization. Presents the results of magnetic resonance imaging (MRI), which can be used for early diagnosis of MSD, as well as dynamic control during treatment. Aim — to assess of neuroimaging signs in patients with spondyloarthrosis and gonarthrosis, depending on the genesis of the disease. Methods. An analytical single-stage study was performed with 123 patients with an established clinical diagnosis of MSP, who were divided into four groups: primary gonarthrosis (36 people), post-traumatic (38 people), spondylogenic (30 people) and x-ray negative (19 people). To study neuroimaging signs, MRI was performed on the devices «OPENMARK 4000» 0.42 T of the company «ANKE», «OPART» 0.35 T of the company «TOSHIBA» and «Superstar» 0.35 T of the company «Neusoft medikal systems» in transversal, sagittal and coronary projections, in T1W, T2W and STIR modes with adipose tissue suppression. Results. During MRI examination, 47.2 % of patients revealed spondyloarthrosis of the III grade, 30,1 % — II grade. 33,3 % had damage in the form of fragmentation of the internal and external meniscus of the knee joint, 30.1 % of cases revealed damage to the internal meniscus in the form of longitudinal splitting and the same number of osteophytes. The most common cases were intervertebral disc sequestration (2,4 %) and expansion of the articular gap of the knee joint (4,1 %), and spondyloarthritis of the I grade (7,3 %). When compared in groups, more pronounced neuroimaging signs were detected in posttraumatic and primary gonarthrosis, and they were significantly lower in spondylogenic genesis. When examining the spine, no differences were found in the groups. Conclusion. The study showed high information content of MRI in CA and GA, which allows for early diagnosis of the disease and differential diagnosis.

Multi-Parameter Magnetic Resonance Imaging Fusion Technology Assists in Bone Diagnosis and Rehabilitation of Prostate Cancer

2021 ◽  
Vol 11 (6) ◽  
pp. 1753-1760
Author(s):  
Yuzhu Jia ◽  
Yibo Ying ◽  
Jianju Feng
Keyword(s):  
Magnetic Resonance Imaging ◽  
Prostate Cancer ◽  
Magnetic Resonance ◽  
Early Diagnosis ◽  
Detection Rate ◽  
Diagnostic Technique ◽  
Diagnostic Value ◽  
Resonance Imaging ◽  
High Risk Factors ◽  
Transrectal Biopsy

Multi-parameter magnetic resonance imaging has been widely used in the diagnosis and evaluation of prostate cancer, and has important guiding significance for clinical diagnosis of prostate cancer and their treatment. This article studies the value of transrectal multiparametric ultrasound (mpUSS) in the diagnosis of clinically meaningful prostate cancer. 102 patients with high risk factors for prostate cancer were examined by mpUSS and mpMRI. The transrectal biopsy (SB) results of the prostate system were regarded as the excellent standard, and the diagnostic value of mpUSS, mpMRl and mpUSS combined with mpMRl examination for clinically meaningful prostate cancer was analyzed. The results showed that 58 of the 102 patients with SB were diagnosed with prostate cancer. Among them, 43 cases were detected by mpUSS, 50 cases were detected by mpMRl, 42 cases were detected by mpUSS combined with mpMRI (series), and 56 cases were detected by mpUSS combined with mpMRl (parallel). Grouped by Gleason score, the detection rate of mpUSS for clinically significant prostate cancer was 83.74%, and the detection rate of mpMRl was 93.5%. The comparison between the two was not statistically significant (P > 0.05), but when the two inspection methods were combined. The detection rate was 97.8%, which was significantly higher than the two inspection methods alone. Therefore, we conclude that mpUSS can be used as an imaging test for the diagnosis of prostate cancer. In addition, mpUSS has a high application value in the diagnosis of prostate cancer. The detection rate of mpUSS combined with mpMRl examination for clinically meaningful prostate cancer is significantly higher than that of mpMRl examination alone, which can be used as a diagnostic technique for early diagnosis of meaningful prostate cancer and can be used as a guide clinicians’ early diagnosis and treatment of meaningful prostate cancer.

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