A Novel Dynamic Measurement of Permeability

1981 ◽  
Vol 21 (06) ◽  
pp. 670-678
Author(s):  
J.H. Moran ◽  
C.M. Papaconstantinou

Abstract A method is proposed for the laboratory determination of permeability; a water-saturated core is shaken and the electrokinetic electromotive forces (emf's) generated thereby are measured as an indication of water movement within the core. This method also can provide a determination of the zeta potential. It is of special interest because of its possible extension to use as a well logging measurement. Introduction Permeability commonly is determined by applying a constant pressure differential lengthwise across a core and measuring the resultant flow through it. Permeability measurements also can be made in situ in boreholes by monitoring transient pressure variations resulting from flow disturbances. In the latter method, fluid and pore compressibilities generally must be taken into account. This paper considers a new laboratory procedure for permeability measurement wherein fluid compressibility again plays a role. The core to be measured is saturated with water, and electrodes are attached to its end faces. It is sealed so that no water can enter or leave. The core then is shaken parallel to its axis with a sinusoidal acceleration. Because the water is compressible, the core acceleration (acting like a synthetic gravity field) will cause some motion of the water relative to the rock frame. The water movement results in the generation of electrokinetic emf's that are monitored in amplitude and phase along with the acceleration. The upper part of Fig. 1 schematically indicates the arrangement of the core. The lower part of Fig. 1 indicates the measurement and interpretation. It is possible to determine k (permeability) and (zeta potential) by measuring a* (complex acceleration). V* (complex electrokinetic emf), and theta (phase angle between V* and a*). Measurements of this kind are described. These measurements, and others not reported here, have met with good success. The technique is of interest because of its good simulation of in-situ measurements and its possible use as a well logging measurement. Also, it can yield gas a by-product. There is the further possibility that it can be extended to measurements of relative permeability by controlling and the conductivity of the fluid. Theory The equations used to described fluid flow, which are a slight generalization of those used in pressure-testing analysis, are (1a) and (1b) in these equations, v is the pore/fluid velocity relative to the rock frame; a is the acceleration of the rock frame; mu and p are the viscosity and the density of the saturating fluid, respectively: K is the bulk modulus of the fluid, which can be corrected for pore compressibility in the usual way; phi and k are the rock porosity and permeability, respectively; and p is the excess pressure resulting from fluid compression. In Eqs. 1a and 1b, it is assumed that the rock frame itself is accelerated as a unit. Thus, a will not depend on the coordinate x along the core. The two terms on the left side of Eq. 1a correspond to flow and compression of the fluid resulting from the driving body force produced by a. SPEJ P. 670^

1980 ◽  
Vol 173 (2) ◽  
pp. 299-301 ◽  
Author(s):  
R.L. Brodzinski ◽  
H.L. Nielson
Keyword(s):  

Author(s):  
Keyvan Khayer ◽  
Adel Shirazy ◽  
Aref Shirazi ◽  
Abdolhamid Ansari ◽  
Hamed Nazerian ◽  
...  

One of the fundamental equations in calculate the saturation of fluid in hydrocarbon reservoirs is the Archie’s equation. In addition to the parameters measured by well logging such as porosity and resistivity, there are others parameters that called Archie’s coefficients. Archie provides constant values for this coefficient base on experimental core’s data, accordance with saturation formula in sandstone. In carbonate reservoirs nevertheless the sandstone reservoirs, high heterogeneity, variety in lithology and texture, shape and distribution of pores, due to this coefficient is not constant. So, variation of tortuosity as a coefficient that depends on the way correlation between pores, is high and considering a constant value due to error in calculation of fluid saturation. In this study, with the stoneley waves measured from DSI tools and required calculation, the value of tortuosity coefficient calculated continuously in well no.10 Darkhovin field. The regression of calculated values with the core data is 83.16 percent, that showed this method is useable for calculation the tortuosity.


1993 ◽  
Vol 115 (3) ◽  
pp. 218-224 ◽  
Author(s):  
P. Kristal ◽  
A. F. Tencer ◽  
T. E. Trumble ◽  
E. North ◽  
D. Parvin

A new technique has been devised for measuring the in situ tension in small ligaments. It is based on measuring the tension in an axially loaded flexible cable with pinned endpoints by deflecting the cable laterally and measuring its lateral load and deformation. Studies were performed in which nylon line and bone ligament bone preparations were placed in a materials tester and loaded in axial tension. Axial load as measured by lateral load and deformation was found to agree with the known load to within 8 percent. The method was sensitive to error in determination of ligament length, nonperpendicularity of the laterally applied load to the long axis of the ligament, and when used in situ, impingement of the ligament on a third bone causing bending. A device, consisting of an LVDT mounted to a rigid frame with its core rod connected to a load cell, was developed. The position of the core rod was controlled by a manual screw drive, and a hook on the other end of the core rod was used to deflect the ligament laterally. This device was applied to the study of tensions in five ligaments of the palmar wrist carpus, in seven cadaver specimens. Results showed that the radioscaphocapitate (RSC) and radiolunate (RL) ligaments had significantly greater tensions than the lunotriquetral (LT), the triquetrocapitate (TC), and scaphocapitate (SC) ligaments. For the four positions of the hand tested, neutral, 14 deg radial and 14 deg ulnar deviation, and 28 deg of extension, ligament tensions were found to be unaffected by position. In all positions tested, all ligaments had measurable tension, demonstrating the importance of ligaments in maintaining the integrity of the wrist carpus.


Author(s):  
J. W. Patching ◽  
R. C. T. Raine ◽  
P. R. O. Barnett

An attempt was made to interpret the core to core variation in oxygen uptake observed during anin situdetermination of sediment community oxygen consumption (SCOC) at a station in the Rockall Trough using the “suspended core” technique. No direct relationships between macrofaunal abundance or biomass and SCOC were observed. The results obtained suggested that the use of experimental chambers of small cross-sectional area (26.2cm2) allow for greater influence on SCOC of the activity of individual organisms which would otherwise be averaged out by larger, grab-type enclosures. The possible significance of other components of the benthos is discussed.


2020 ◽  
Vol 35 (2) ◽  
pp. 238-245 ◽  
Author(s):  
Miaohong He ◽  
Xiaoping Xia ◽  
Xiaolong Huang ◽  
Jinlong Ma ◽  
Jieqiong Zou ◽  
...  

Rapid determination of the original boron composition from altered basaltic glass by SIMS boron isotopic profile analysis from the core to rim.


Author(s):  
M. Boublik ◽  
V. Mandiyan ◽  
S. Tumminia ◽  
J.F. Hainfeld ◽  
J.S. Wall

Success in protein-free deposition of native nucleic acid molecules from solutions of selected ionic conditions prompted attempts for high resolution imaging of nucleic acid interactions with proteins, not attainable by conventional EM. Since the nucleic acid molecules can be visualized in the dark-field STEM mode without contrasting by heavy atoms, the established linearity between scattering cross-section and molecular weight can be applied to the determination of their molecular mass (M) linear density (M/L), mass distribution and radius of gyration (RG). Determination of these parameters promotes electron microscopic imaging of biological macromolecules by STEM to a quantitative analytical level. This technique is applied to study the mechanism of 16S rRNA folding during the assembly process of the 30S ribosomal subunit of E. coli. The sequential addition of protein S4 which binds to the 5'end of the 16S rRNA and S8 and S15 which bind to the central domain of the molecule leads to a corresponding increase of mass and increased coiling of the 16S rRNA in the core particles. This increased compactness is evident from the decrease in RG values from 114Å to 91Å (in “ribosomal” buffer consisting of 10 mM Hepes pH 7.6, 60 mM KCl, 2 m Mg(OAc)2, 1 mM DTT). The binding of S20, S17 and S7 which interact with the 5'domain, the central domain and the 3'domain, respectively, continues the trend of mass increase. However, the RG values of the core particles exhibit a reverse trend, an increase to 108Å. In addition, the binding of S7 leads to the formation of a globular mass cluster with a diameter of about 115Å and a mass of ∽300 kDa. The rest of the mass, about 330 kDa, remains loosely coiled giving the particle a “medusa-like” appearance. These results provide direct evidence that 16S RNA undergoes significant structural reorganization during the 30S subunit assembly and show that its interactions with the six primary binding proteins are not sufficient for 16S rRNA coiling into particles resembling the native 30S subunit, contrary to what has been reported in the literature.


1961 ◽  
Vol 38 (4) ◽  
pp. 545-562 ◽  
Author(s):  
L. Kecskés ◽  
F. Mutschler ◽  
I. Glós ◽  
E. Thán ◽  
I. Farkas ◽  
...  

ABSTRACT 1. An indirect paperchromatographic method is described for separating urinary oestrogens; this consists of the following steps: acidic hydrolysis, extraction with ether, dissociation of phenol-fractions with partition between the solvents. Previous purification of phenol fraction with the aid of paperchromatography. The elution of oestrogen containing fractions is followed by acetylation. Oestrogen acetate is isolated by re-chromatography. The chromatogram was developed after hydrolysis of the oestrogens 'in situ' on the paper. The quantity of oestrogens was determined indirectly, by means of an iron-reaction, after the elution of the iron content of the oestrogen spot, which was developed by the Jellinek-reaction. 2. The method described above is satisfactory for determining urinary oestrogen, 17β-oestradiol and oestriol, but could include 16-epioestriol and other oestrogenic metabolites. 3. The sensitivity of the method is 1.3–1.6 μg/24 hours. 4. The quantitative and qualitative determination of urinary oestrogens with the above mentioned method was performed in 50 pregnant and 9 non pregnant women, and also in 2 patients with granulosa cell tumour.


Author(s):  
Kranti Singh ◽  
Surajpal Verma ◽  
Shyam Prasad ◽  
Indu Bala

Ciprofloxacin hydrochloride loaded Eudragit RS100 nanoparticles were prepared by using w/o/w emulsification (multiple emulsification) solvent evaporation followed by drying of nanoparticles at 50°C. The nanoparticles were further incorporated into the pH-triggered in situ gel forming system which was prepared using Carbopol 940 in combination with HPMC as viscosifying agent. The developed nanoparticles was evaluated for particle size, zeta potential value and loading efficiency; nanoparticle incorporated in situ gelling system was evaluated for pH, clarity, gelling strength, rheological studies, in-vitro release studies and ex-vivo precorneal permeation studies. The nanopaticle showed the mean particle size varying between 263.5nm - 325.9 nm with the mean zeta potential value of -5.91 mV to -8.13 mV and drug loading capacity varied individually between 72.50% to 98.70% w/w. The formulation was clear with no suspended particles, showed good gelling properties. The gelling was quick and remained for longer time period. The developed formulation was therapeutically efficacious, stable and non-irritant. It provided the sustained release of drug over a period of 8-10 hours.


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