scholarly journals Laparoscopic Petersen’s Hernia Reduction Was Associated With A Better Clinical Course Than Open Reduction After Gastrectomy: A Multicenter Observational Cohort Study

2020 ◽  
Author(s):  
Jae-Seok Min ◽  
Kyung Won Seo ◽  
Sangho Jeong ◽  
Ki Hyun Kim ◽  
Ji-ho Park ◽  
...  
Keyword(s):  
Cohort Study ◽  
Clinical Course ◽  
Recovery Period ◽  
Laparoscopic Approach ◽  
Length Of Hospital Stay ◽  
Postoperative Recovery ◽  
Multicenter Cohort Study ◽  
Ph Reduction ◽  
Observational Cohort ◽  
Petersen’S Hernia

Abstract Background The aim of this multicenter cohort study was to compare the clinical courses between open and laparoscopic Petersen’s hernia (PH) reduction.Materials and method We retrospectively collected the clinical data of patients who underwent PH repair surgery after gastrectomy for gastric cancer from 2015-2018. Forty patients underwent PH reduction operations that were performed by six expert surgeons at four hospitals. Among the 40 patients, 15 underwent laparoscopic PH reduction (LPH), and 25 underwent open PH reduction (OPH), including 4 patients who underwent LPH but required conversion to OPH.Results We compared the clinical factors between the LPH and OPH groups. In the clinical course, we found no differences in operation times or intraoperative bowel injury, morbidity, or mortality rates between the two groups (p>0.05). However, the number of days on a soft fluid diet (OPH vs. LPH; 5.8 vs. 3.7 days, p=0.03) and length of hospital stay (12.6 vs. 8.2 days, p=0.04) were significantly less in the LPH group than the OPH group. Regarding postoperative complications, the OPH group had a case of pneumonia and sepsis with multi-organ failure, which resulted in mortality. In the LPH group, one patient experienced recurrence and required reoperation for PH.Conclusion Laparoscopic PH reduction was associated with a faster postoperative recovery period than open PH reduction, with a similar incidence of complications. The laparoscopic approach should be considered an appropriate strategy for PH reduction.

scholarly journals A comparison of postoperative outcomes after open and laparoscopic reduction of Petersen's Hernia: a multicenter observational cohort study

BMC Surgery ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Jae-Seok Min ◽  
Kyung Won Seo ◽  
Sang-Ho Jeong ◽  
Ki Hyun Kim ◽  
Ji-ho Park ◽  
...  
Keyword(s):  
Cohort Study ◽  
Recovery Period ◽  
Laparoscopic Approach ◽  
Length Of Hospital Stay ◽  
Postoperative Recovery ◽  
Multicenter Cohort Study ◽  
Ph Reduction ◽  
Observational Cohort ◽  
Petersen’S Hernia ◽  
Similar Incidence

Abstract Background The aim of this multicenter cohort study was to compare the clinical courses between open and laparoscopic Petersen’s hernia (PH) reduction. Method We retrospectively collected the clinical data of patients who underwent PH repair surgery after gastrectomy for gastric cancer from 2015–2018. Forty patients underwent PH reduction operations that were performed by six surgeons at four hospitals. Among the 40 patients, 15 underwent laparoscopic PH reduction (LPH), and 25 underwent open PH reduction (OPH), including 4 patients who underwent LPH but required conversion to OPH. Results We compared the clinical factors between the LPH and OPH groups. In the clinical course, we found no differences in operation times or intraoperative bowel injury, morbidity, or mortality rates between the two groups (p > 0.05). However, the number of days on a soft fluid diet (OPH vs. LPH; 5.8 vs. 3.7 days, p = 0.03) and length of hospital stay (12.6 vs. 8.2 days, p = 0.04) were significantly less in the LPH group than the OPH group. Regarding postoperative complications, the OPH group had a case of pneumonia and sepsis with multi-organ failure, which resulted in mortality. In the LPH group, one patient experienced recurrence and required reoperation for PH. Conclusion Laparoscopic PH reduction was associated with a faster postoperative recovery period than open PH reduction, with a similar incidence of complications. The laparoscopic approach should be considered an appropriate strategy for PH reduction in selected cases.

scholarly journals Effectiveness and adverse events of endoscopic clipping versus band ligation for colonic diverticular hemorrhage: A large-scale multicenter cohort study

Endoscopy ◽  
2021 ◽  
Author(s):  
Katsumasa Kobayashi ◽  
Naoyoshi Nagata ◽  
Yohei Furumoto ◽  
Atsushi Yamauchi ◽  
Atsuo Yamada ◽  
...  
Keyword(s):  
Cohort Study ◽  
Large Scale ◽  
Length Of Hospital Stay ◽  
Multicenter Cohort Study ◽  
Band Ligation ◽  
Prolonged Length ◽  
Diverticular Hemorrhage ◽  
Significant Difference ◽  
Colonic Diverticular Hemorrhage ◽  
Endoscopic Clipping

Background and study aims: Prior studies have shown the effectiveness of endoscopic band ligation (EBL) and clipping for colonic diverticular hemorrhage (CDH) but have been small and conducted at single centers. Thus, we investigated which was the more effective and safe treatment in a multicenter long-term cohort study. Patients and methods: We reviewed data for 1,679 patients with CDH who were treated with EBL (n=638) or clipping (n=1,041) between January 2010 and December 2019 at 49 hospitals across Japan (CODE BLUE-J Study). Logistic regression analysis was used to compare outcomes between the two treatments. Results: In multivariate analysis, EBL compared with clipping was independently associated with reduced risk of early rebleeding (adjusted odds ratio [AOR] 0.46; p<0.001) and late rebleeding (AOR 0.62; p<0.001). These significantly lower rebleeding rates with EBL were evident regardless of active bleeding or early colonoscopy. No significant difference was found between the treatments in the rate of initial hemostasis or mortality. EBL compared with clipping independently reduced the risk of need for interventional radiology (IVR) (AOR 0.37; p=0.006) and prolonged length of hospital stay (LOS) (AOR 0.35; p<0.001), but not need for surgery. Diverticulitis developed in 1 patient (0.16%) following EBL and 2 patients (0.19%) following clipping. Perforation occurred in 2 patients (0.31%) following EBL and none following clipping. Conclusions: Analysis of our large endoscopy dataset suggests that EBL is an effective and safe endoscopic therapy for CDH offering the advantages of lower early and late rebleeding rates, reduced need for IVR, and shorter LOS.

scholarly journals Hospitalized Children with Critical SARS-CoV-2 Infection Cared for in a Limited Resource Setting: Multicenter Cohort Study

2021 ◽  
Author(s):  
Emmerson C.F. de Fariasa ◽  
Jefferson P. Piva ◽  
Manoel J.C. Pavão Junior ◽  
Susan C.D. Sales ◽  
Luciana M.P. Nascimento ◽  
...  
Keyword(s):  
Cohort Study ◽  
Children And Adolescents ◽  
Invasive Mechanical Ventilation ◽  
Laboratory Data ◽  
Length Of Hospital Stay ◽  
Limited Resource ◽  
Hospitalized Children ◽  
Multicenter Cohort Study ◽  
Multicenter Cohort ◽  
Resource Setting

Abstract Background: Some children can develop severe forms of SARS-CoV-2 infection either acutely or later, as represented by multisystemic inflammatory syndrome in children (MIS- C). To identify the risk factors for worse outcomes in hospitalized children and adolescents with severe acute SARS-CoV-2 infection and MIS-C. Methods: This multicenter cohort study included all children and adolescents with confirmed or suspected critical SARS-CoV-2 infection admitted to the PICU between April 2020 and September 2021. The exclusion criteria were incomplete vaccinal status, immunocompromised status, and end-of-life decision. The main variables analyzed were epidemiological, clinical, and laboratory data, and ventilator settings at admission and after 72 h. The patients were divided into three groups (G): confirmed coronavirus disease (COVID-19) with MIS-C criteria (G1), confirmed COVID-19 without MIS-C criteria (G2), and MIS-C criteria without confirmed COVID-19. Results: The median age of the patients was 28 months in G1, with comorbidities in 40 patients (72.7%) (p < 0.0001). The duration of exposure (median 23 days; p = 0.004) and fever were longer in G1 (12 days; p = 0.001). Moreover, invasive mechanical ventilation (IMV) was required in 44 patients (80%, p < 0.0001), and cardiogenic shock occurred in 26 patients (54.2%, p < 0.0001) in G1. Subnutrition was most frequent in G1 in 55 cases (57.3%; p = 0.01). Under nutrition (< 2 SD for weight), longer exposure time (odds ratio [OR]: 2.11; 95% confidence interval [CI]: 1.37–3.25; p = 0.001), IMV time (OR: 2.6; 95% CI: 1.15–5.85; p = 0.03), and length of hospital stay (OR: 10.94; 95% CI: 1.93–63.1; p = 0.007) were associated with critical MIS-C in G1. Conclusions: In the Brazilian Amazon area, specifically in the Pará state, we identified a cluster of more severe forms of pediatric acute or late SARS-CoV-2 infection.

scholarly journals An observational cohort study on shortened dental arches—clinical course during a period of 27–35 years

2012 ◽  
Vol 17 (3) ◽  
pp. 859-866 ◽  
Author(s):  
Anneloes E. Gerritsen ◽  
Dick J. Witter ◽  
Ewald M. Bronkhorst ◽  
Nico H. J. Creugers
Keyword(s):  
Cohort Study ◽  
Clinical Course ◽  
Observational Cohort Study ◽  
Observational Cohort ◽  
Shortened Dental Arches

scholarly journals Can Waterlow score predict 30-day mortality and length of stay in acutely admitted medical patients (aged ≥65 years)? Evidence from a single centre prospective cohort study

BMJ Open ◽  
2019 ◽  
Vol 9 (11) ◽  
pp. e032347
Author(s):  
James Wei Wang ◽  
Phillip Smith ◽  
Shah-Jalal Sarker ◽  
Sophie Elands ◽  
Amelia Oliveira ◽  
...  
Keyword(s):  
Cohort Study ◽  
Assessment Tool ◽  
Respiratory Infections ◽  
Length Of Hospital Stay ◽  
District General Hospital ◽  
Medical Patients ◽  
Medical Specialties ◽  
Significant Difference ◽  
Unit Increase ◽  
Observational Cohort

ObjectiveThis study aimed to explore the potential for the Waterlow score (WS) to be used as a predictor of 30-day mortality and length of hospital stay (LHS) in acutely admitted medical patients aged 65 years and older.DesignProspective observational cohort study.SettingUK District General Hospital.Subjects834 consecutive patients aged 65 years and older admitted acutely to medical specialties between 30 May and 22 July 2014.MethodsAdmission WS (range 4–64) assessment paired with the patient’s status at 30 days in terms of mortality and their LHS.Primary outcomes30-day mortality and length of inpatient stay.Results834 consecutive acute medical admissions had their WS recorded. 30-day mortality was 13.1% (109 deaths). A significant difference in the distribution of WS (p<0.001) was seen between those who survived (median 12) and those who died (median 16) within 30 days, particularly within respiratory (p<0.001), stroke (p<0.001), cardiology (p<0.016), non-respiratory infections (p<0.018) and trauma (p<0.044) subgroups. Odds of dying within 30 days increased threefold for every 10-unit increase in the WS (p<0.001, 95% CI 2.1 to 4.3). LHS was also positively linearly associated with the WS in those who survived 30 days (median=5, IQR=10; r=0.32, p<0.01). A five-unit increase in WS was associated with approximately 5 days increase in LHS. On the other hand, quadratic regression showed this relationship was curvilinear and negative (concave) for those who died within 30 days where a five-unit increase in WS was associated with an approximately 10 days decrease in LHS.ConclusionThis study demonstrates an association between a high WS and both 30-day mortality and LHS. This is particularly significant for mortality in patients in the respiratory, stroke and cardiac subcategories. The WS, a nursing-led screening tool that is carried out on virtually all admissions to UK hospitals, could have additional use at the time of patient admission as a risk assessment tool for 30-day mortality as well as a predictor of LHS.

Oseltamivir Resistance in Severe Influenza A(H1N1)pdm09 Pneumonia and Acute Respiratory Distress Syndrome: A French Multicenter Observational Cohort Study

2019 ◽  
Vol 71 (4) ◽  
pp. 1089-1091 ◽  
Author(s):  
Sylvie Behillil ◽  
Faten May ◽  
Slim Fourati ◽  
Charles-Edouard Luyt ◽  
Thomas Chicheportiche ◽  
...  
Keyword(s):  
Acute Respiratory Distress Syndrome ◽  
Cohort Study ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Influenza A ◽  
Distress Syndrome ◽  
Multicenter Cohort Study ◽  
Oseltamivir Resistance ◽  
Influenza A H1n1 ◽  
Observational Cohort

Abstract In a multicenter cohort study including 22 oseltamivir-treated patients with influenza A(H1N1)pdm09 acute respiratory distress syndrome, prevalence of the H275Y substitution in the neuraminidase, responsible for highly reduced sensitivity to oseltamivir, was 23%. Patients infected with the H275Y mutant virus had higher day 28 mortality than others (80% vs 12%; P = .011).

Sign in / Sign up

Export Citation Format

Share Document