scholarly journals Association Between Levels of Depression Symptoms and Moderately Increased Levels of the Inflammation Marker Albuminuria Is Explained by Age and Comorbidity.

Author(s):  
Solfrid Romundstad ◽  
Torfinn Hynnekleiv

Abstract Background: The study aimed to examine whether there are associations between levels of depression symptoms and levels of the inflammation marker albuminuria. Materials and methods: The 8303 participants in this cross-sectional study were subjects from the second survey of the Trøndelag Health Study (HUNT, Norway). Depression symptoms were assessed by the Hospital Anxiety and Depression Scale (HADS). Logistic regression analysis was performed to estimate the odds ratio (OR) for moderately increased albuminuria (ACR > 3.0 mg/mmol) according to different HADS subgroups and -scores.Results: Unadjusted ORs for moderately increased albuminuria were significantly increased in those with HADS > 8 (OR 1.27, 95% CI 1.05-1.54, p=0.013) and HADS > 11 (OR 1.59, 95% CI 1.19-2.14, p=0.002). However, after adjusting for age and sex, only HADS > 11 was significantly associated with ACR > 3.0 mg/mmol (OR 1.46, 95% CI 1.08-1.98, p=0.014), and after multivariable adjustments for cardiovascular risk factors and comorbidity, there were no significant associations. Conclusion: The positive and significant association between moderately increased albuminuria and symptoms of depression found in unadjusted analyses weakened and disappeared after adjustments. Although individuals with depressive symptoms had albuminuria more often than individuals without such symptoms, albuminuria may reflect other comorbidity and inflammation conditions than depression.

2021 ◽  
Vol 9 ◽  
pp. 205031212110400
Author(s):  
Kemal Jemal ◽  
Tinsae Abeya Geleta ◽  
Berhanu Senbeta Deriba ◽  
Mukemil Awol

Objectives: The coronavirus disease 2019 pandemic has caused high morbidity and mortality in older adults over the world. Because the coronavirus disease 2019 pandemic greatly affects older adults who have a preexisting health condition, they are generally susceptible to a high incidence of severe symptoms of anxiety and depression. Therefore, we aimed to assess the prevalence of anxiety and depression symptoms in older adults during the coronavirus disease 2019 pandemic. Methods: Community-based cross-sectional study was completed in August 2020. Standardized and pretested General Anxiety Disorder–7 and Geriatric Depression Scale were used to screen the symptoms of anxiety and depression, respectively. Data were entered into EpiData (version 4.3.2) and transferred to SPSS (version 24) for further analysis. Bivariate and multivariate logistic regression analyses were carried out to determine the significantly associated variables with a 95% confidence interval at p < 0.05. Results: Of the total older adults interviewed, 68.7% had developed symptoms of anxiety and 59.9% had symptoms of depression during the coronavirus disease 2019 pandemic. Female participants, having a chronic disease and poor knowledge of the coronavirus disease 2019 pandemic, were significantly associated with anxiety symptoms. Age category of 81 to 90 and above 90, lack of social support, and having a chronic disease were significantly associated with symptoms of depression. Conclusion: The symptoms of anxiety and depression among older adults in the North Shoa Zone during coronavirus disease 2019 were higher than before the coronavirus disease 2019 happened. The results were evidence points for developing a psychological intervention to tackle the older adults’ mental health needs in the community during and after the coronavirus disease 2019 pandemic.


PLoS ONE ◽  
2019 ◽  
Vol 14 (1) ◽  
pp. e0210111 ◽  
Author(s):  
Heidi Turon ◽  
Mariko Carey ◽  
Allison Boyes ◽  
Bree Hobden ◽  
Sophie Dilworth ◽  
...  

Author(s):  
Wajana Thaweerat ◽  
Wannarat Amornnimit Pongpirul ◽  
Wisit Prasithsirikul

AbstractAnxiety and depression in hospitalized COVID-19 patients in Thailand during the first wave of the pandemic were investigated. Thai version of Hospital Anxiety and Depression Scale (HADS) was chosen as an instrument for evaluation. Thirty-two voluntary participants completed the questionnaire. Three (9.4%) respondents had abnormal anxiety sub-scale scores while no respondents had abnormal depression sub-scale scores. There was no statistical demographic difference between the anxiety and non-anxiety groups.


Author(s):  
Carlos Izaias Sartorão Filho ◽  
Wilson Conte de Las Villas Rodrigues ◽  
Ricardo Beauchamp de Castro ◽  
Arlete Aparecida Marçal ◽  
Shirlene Pavelqueires ◽  
...  

AbstractAimto evaluate anxiety and depression disorders among medical students during COVID-19 pandemic.Methodscross-sectional study of medical students conducted in May 2020 with questionnaires regarding social and demographic status and GAD-7 for anxiety and PHQ-9 for depression questionnaires.Resultsparticipated 340 (97.98%) students. Average GAD-7 score was 9.18 (M = 9.18; SD = 4.75); average PHQ-9 score was 12.72 (M = 12.72; SD = 6.62). Results indicate a positive significant relationship between GAD-7 and females, and social distancing affecting finances. Using cut-off score of 10 for GAD-7, 157 (46.17%) students were identified with moderated or severe symptoms of anxiety. For PHQ-9 score, using cut-off of 10, 219 (64.41%) students were identified with moderate or severe symptoms of depression; results indicate a positive significant relationship between PHQ-9 and females and between social distancing affecting finances.Conclusionanalysis demonstrated a higher prevalence of moderated and severe anxiety and depression symptoms among medical students during COVID-19 pandemic, significantly among women and on medical students relating financial impairment related to COVID-19 epidemic.The project was approved by the Research Ethics Committee of Institution under report number CAAE: 30718220.5.0000.8547


2020 ◽  
Author(s):  
Carlos Izaias Filho

UNSTRUCTURED Aim: to evaluate anxiety and depression disorders among medical students during COVID-19 pandemic. Methods: cross-sectional study of medical students conducted in May 2020 with questionnaires regarding social and demographic status and GAD-7 for anxiety and PHQ-9 for depression questionnaires. Results: participated 340 (97.98%) students. Average GAD-7 score was 9.18 (M = 9.18; SD = 4.75); average PHQ-9 score was 12.72 (M = 12.72; SD = 6.62). Results indicate a positive significant relationship between GAD-7 and females, and social distancing affecting finances. Using cut-off score of 10 for GAD-7, 157 (46.17%) students were identified with moderated or severe symptoms of anxiety. For PHQ-9 score, using cut-off of 10, 219 (64.41%) students were identified with moderate or severe symptoms of depression; results indicate a positive significant relationship between PHQ-9 and females and between social distancing affecting finances. Conclusion: analysis demonstrated a higher prevalence of moderated and severe anxiety and depression symptoms among medical students during COVID-19 pandemic, significantly among women and on medical students relating financial impairment related to COVID-19 pandemic. INTERNATIONAL REGISTERED REPORT RR2-10.1101/2020.06.24.20138925


2020 ◽  
Vol 4 (1) ◽  
pp. 2514183X2092595
Author(s):  
Heiko Pohl ◽  
Andreas R Gantenbein ◽  
Peter S Sandor ◽  
Jean Schoenen ◽  
Colette Andrée

Objective: The aim of this study is to evaluate how anxiety influences the burden of disease of cluster headache. Methods: Participants completed a modified version of the EUROLIGHT questionnaire. Anxiety was measured with the anxiety subscale of the Hospital Anxiety and Depression scale. An elevated level of anxiety was assumed when eight or more points were scored. Results: The data of 1089 participants were taken for analysis. The score of the anxiety subscale of the Hospital Anxiety and Depression Scale (HADS-A) correlated weakly with the number of attacks in the last 30 days ( r = 0.17). A score of eight and above in the HADS-A was associated with hurting oneself during an attack (odds ratio (OR) = 2.63), worrying about future attacks (OR = 2.95) and reporting of both failed relationships (OR = 2.81) and career problems (OR = 2.65). The odds of feeling understood by family and friends as well as colleagues and employers were lower in anxious persons (OR = 0.35 and 0.40, respectively). Conclusions: Anxiety complicates dealing with cluster headache and strongly aggravates its burden. Instead of finding help in others, anxious persons feel misunderstood and withdraw; relationships fail and difficulties at work arise.


2020 ◽  
Author(s):  
Miyabi Uda ◽  
Motomu Hashimoto ◽  
Ryuji Uozumi ◽  
Mie Torii ◽  
Takao Fujii ◽  
...  

Abstract Introduction / objectives Management of anxiety and depression in rheumatoid arthritis (RA) patients is vital. Previous studies investigating this topic are conflicting, and this topic still has not been thoroughly investigated. This study aimed to clarify the association of disease activity with anxiety and depression after controlling for physical disability, pain, and treatment. Method We conducted a cross-sectional study of RA patients from the Kyoto University Rheumatoid Arthritis Management Alliance cohort. For assessments, we used the Disease Activity Score (DAS28), Health Assessment Questionnaire Disability Index (HAQ-DI), and Hospital Anxiety Depression Scale. Depression and anxiety were defined by a Hospital Anxiety Depression Scale score ≥8. We then performed multivariable logistic regression analyses. Results Of 517 participants, 17.9% had anxiety, and 28.2% had depression. The multivariable logistic regression analyses showed patients with DAS28-based non-remission had low association with anxiety (odds ratio [OR] [95% confidence interval {CI}], 0.93 [0.48–1.78]: p = 0.82) but slight association with depression (OR [95% CI], 1.45 [0.81–2.61]: p = 0.22). However, severity of the patient’s global assessment (PtGA) on DAS28 was associated with anxiety (OR [95% CI], 1.15 [1.02–1.29]; p = 0.03) and depression (OR [95% CI], 1.21 [1.09–1.35]; p < 0.01). Additionally, HAQ-DI-based non-remission was associated with anxiety (OR [95% CI], 3.51 [1.85–6.64]; p < 0.01) and depression (OR [95% CI], 2.65 [1.56–4.50]; p < 0.01). Younger patients (OR [95% CI], 0.83 [0.68–1.01]; p = 0.07) and patients not treated with methotrexate (OR [95% CI], 0.67 [0.40–1.13]; p = 0.13) tended to suffer from anxiety. Patients using steroids had a closer association with depression than those not using them (OR [95% CI], 1.66 [1.03–2.67]; p = 0.04). Conclusions Assessment of disease activity, PtGA, and HAQ-DI are important for assessing anxiety and depression in RA patients. Attention should be paid to improving PtGA and physical function.


2020 ◽  
Vol 4 (3) ◽  
pp. 809-812
Author(s):  
Regan Shakya ◽  
Bandana Gautam

Introduction: Chronic Obstructive Pulmonary Disease (COPD) is a progressive disabling illness characterized by persistent airflow limitation affecting physical, psychological and social aspect of the individual. Amongst the associated co morbidities, depression and anxiety has been identified as common modifiable psychiatric comorbidities of COPD which impacts the patient’s quality of life.  Objectives: To establish the prevalence of depression and anxiety among the COPD patient and determine the association between them. Methodology: The cross sectional study was conducted at Dhulikhel Hospital. We used a convenient sampling method to recruit seventy three COPD participants admitted in the Medicine ward. We interviewed the participants to evaluate anxiety and depression using the Nepali version of Hospital Anxiety and Depression Scale questionnaire. We considered positive result of anxiety and depression when the Hospital Anxiety and Depression score was above eight.  Results: Depressive and Anxiety symptoms were observed in 30 % and 33% of the participants respectively. Similarly 20% of the participants had both the symptoms of depression and anxiety. The association between depression and anxiety was found to be highly significant (p<0.001). In the multivariate model the odds of depression and anxiety was nine percent increase with every one year increase in age after adjusting for gender and duration of illness. (adjusted OR: 1.07; CI 1.00- 1.17; p-value: 0.03). In an unadjusted model depression was significantly associated to every year increase in age (unadjusted OR: 1.07; CI: 1.00- 1.13; p-value: 0.03) Conclusion: Depression and anxiety is prevalent among COPD patient at Dhulikhel hospital with one fifth of the patient demonstrating both depression and anxiety symptoms.


2015 ◽  
Vol 19 (3) ◽  
pp. 297-303 ◽  
Author(s):  
Mohammed A. Alshahwan

Background Psychiatric disorders are common among patients with physical illnesses. Objectives To estimate the prevalence of anxiety and depression in Arab dermatology patients and to study its association with the patients’ characteristics. Materials and Methods A cross-sectional study was carried out on 875 patients attending the Dermatology Clinic at King Khalid University Hospital in Riyadh, Saudi Arabia. Each patient was asked to complete the Hospital Anxiety and Depression Scale and the demographic-clinical questionnaire. Results The frequency of anxiety and depression in Arab dermatology patients was 29% for anxiety and 14% for depression. These frequencies were not related to sociodemographic and clinical variables (p > .05), except skin disease type (p < .05). Patients suffering from hair loss had the highest anxiety and depression scores (OR 1.725 [95% CI 1.247-2.386] and OR 1.686 [95% CI 1.101-2.581], respectively). On the other hand, patients suffering from psoriasis had the highest depression scores (OR 2.909 [95% CI 1.611-5.254]). Conclusion Anxiety and depression are frequent among Arab dermatology patients.


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