Vaccine Research in COVID-19: A Living Scoping Review Protocol

Abstract Background: Coronavirus disease 2019 (COVID-19) has become a global public problem and a pandemic event. Since the epidemic outbreak, deaths and cumulative confirmed positive cases have continued rising rapidly worldwide. Vaccines are regarded as one of the most effective means of preventing and controlling an epidemic. With the spread of COVID-19, a large number amount of literature on vaccines has been published recently. There is a pressing need to map the research activities of COVID-19 vaccines.Methods: Following Arksey and O’Malley’s framework and Joanna Briggs Institute (JBI) methodological guidance, a scoping review is proposed to summarize the extent/breadth, range, and nature of evidence in research related to COVID-19 vaccines. Based on the research questions we have developed by ours, a comprehensive search will be performed in Cochrane Library, Embase, PubMed, Web of Science, CNKI, CBM, VIP, and WanFang databases by two independent reviewers. According to our predefined inclusion criteria, pairs of reviewers will independently assess the eligibility of identified studies from the databases. Following literature selection, pairs of reviewers will extract relevant information related to our research questions. The methodological quality and reporting quality of key evidence types (i.e., randomized controlled trials, systematic reviews and meta-analyses) will be evaluated using commonly used tools, if possible. Qualitative synthesis and descriptive statistics will be used to summarize and present the results. In addition, new or updated meta-analysis will be conducted to pool the data available in included primary studies where possible. To track the trends in COVID-19 vaccines research, we plan to update our results every 2~3 months. Preparation of this scoping review protocol referred to PRISMA-P checklist, and the reporting of the following full-text will be using PRISMA-ScR guidelines.Discussion: We believe the results of this scoping review on COVID-19 vaccine will contribute to provide foundational knowledge, and have significant value for the research and practice of COVID-19 vaccines. The findings will also allow us to identify research gaps on this topic and help to guide the future research of COVID-19 vaccines well.

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Hypnotherapy for Procedural Pain and Distress in Children: A scoping Review Protocol

Pain Medicine ◽

10.1093/pm/pnab038 ◽

2021 ◽

Author(s):

Daly Geagea ◽

Zephanie Tyack ◽

Roy Kimble ◽

Lars Eriksson ◽

Vince Polito ◽

...

Keyword(s):

Scoping Review ◽

Grey Literature ◽

Cochrane Library ◽

Procedural Pain ◽

Future Research ◽

Theoretical Frameworks ◽

Eligibility Criteria ◽

Pharmacological Agents ◽

Review Protocol ◽

Meta Analyses

Abstract Objective Inadequately treated pain and distress elicited by medical procedures can put children at higher risks of acute and chronic biopsychosocial sequelae. Children can benefit from hypnotherapy, a psychological tailored intervention, as an adjunct to pharmacological agents to address the multiple components of pain and distress. Despite providing evidence on the effectiveness and potential superiority of hypnotherapy to other psychological interventions, research on hypnotherapy for paediatric procedural pain and distress has been predominantly limited to oncology and needle procedures. Plus, there is a lack of reporting of intervention manuals, factors influencing hypnotic responding, pain unpleasantness outcomes, theoretical frameworks, adverse events, as well as barriers and facilitators to the feasibility of delivering the intervention and study procedures. The proposed review aims to map the range and nature of the evidence on hypnotherapy for procedural pain and distress in children to identify gaps in literature and areas requiring further investigation. Methods This review will follow the Arksey and O'Malley (2005) methodology and incorporate additional scoping review recommendations by The Joanna Briggs Institute and Preferred Reporting Items for Systematic reviews and Meta-Analyses. Relevant studies will be identified through searching published literature databases (PubMed, Cochrane Library, PsycINFO, Embase, CINAHL, Scopus and Web of Science) and grey literature in addition to hand-searching of reference lists and key journals. Two authors will independently screen titles and abstracts of search results followed by full-texts review against eligibility criteria. Conclusion Findings are anticipated to guide future research and inform the development of tailored hypnotic interventions in children.

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An integrative systematic review of creative arts interventions for older informal caregivers of people with neurological conditions

PLoS ONE ◽

10.1371/journal.pone.0243461 ◽

2020 ◽

Vol 15 (12) ◽

pp. e0243461

Author(s):

J. Yoon Irons ◽

Gulcan Garip ◽

Ainslea J. Cross ◽

David Sheffield ◽

Jamie Bird

Keyword(s):

Meta Analysis ◽

Informal Caregivers ◽

Small Sample ◽

Cochrane Library ◽

Future Research ◽

Creative Arts ◽

Qualitative Synthesis ◽

Current Review ◽

Neurological Conditions ◽

Creative Interventions

Objective We aimed to assess and synthesise the current state of quantitative and qualitative research concerning creative arts interventions for older informal caregivers of people with neurological conditions. Methods A systematic search was employed to identify studies that examined creative arts interventions for older informal caregivers, which were synthesised in this integrative review. We searched the following databases: MEDLINE, PubMed, EBSCO, CINAHL, EMBASE, PsycINFO, Cochrane Library, Scopus, Web of Science, and Google Scholar. We also backwards searched references of all relevant studies and inspected trials registers. Results Of the 516 studies identified, 17 were included: one was quantitative, nine were qualitative and seven used mixed methods. All included quantitative studies were pilot or feasibility studies employing pre- and post-test design with small sample sizes. Studies varied in relation to the type of creative intervention and evaluation methods, which precluded meta-analysis. Large effect sizes were detected in wellbeing measures following singing and art interventions. The qualitative synthesis highlighted that interventions created space for caregivers to make sense of, accept and adapt to their identity as a caregiver. Personal developments, such as learning new skills, were viewed positively by caregivers as well as welcoming the opportunity to gain cognitive and behavioural skills, and having opportunities to unload emotions in a safe space were important to caregivers. Group creative interventions were particularly helpful in creating social connections with their care-recipients and other caregivers. Conclusions The current review revealed all creative interventions focused on caregivers of people living with dementia; subsequently, this identified gaps in the evidence of creative interventions for informal caregivers of other neurological conditions. There are encouraging preliminary data on music and art interventions, however, little data exists on other art forms, e.g., drama, dance. Creative interventions may appeal to many caregivers, offering a range of psycho-social benefits. The findings of the current review open the way for future research to develop appropriate and creative arts programmes and to test their efficacy with robust tools.

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Effectiveness of Physiotherapy to Promote Motor Recovery in Individuals with Stroke: A Systematic Review Protocol

10.21203/rs.3.rs-1169559/v1 ◽

2022 ◽

Author(s):

Shehong Zhang ◽

Hongyu Xie ◽

Chuanjie Wang ◽

Fengfeng Wu ◽

Xin Wang

Keyword(s):

Systematic Review ◽

Motor Function ◽

Systematic Reviews ◽

Evaluation System ◽

Meta Analysis ◽

Primary Data ◽

Cochrane Library ◽

Systematic Review Protocol ◽

Qualitative Synthesis ◽

Review Protocol

Abstract Introduction: Motor function is essential in our daily lives, one of the most common impairments caused by stroke is loss of functional movement. Over 70% of stroke survivors have motor or other neurological functional disabilities. However, rehabilitation of motor function suffered from a stroke can be rather difficult due to the complexity of organs and systems related to motor function, as well as the neural system that supported motor function. In particularly, previous evidence for the effectiveness of physiotherapy, a commonly prescribed intervention method for people with stroke, that recover motor function in people following a stroke is varied and limited in the chronic rehabilitation phase and therefore has never been reviewed systematically. With the progress of study in neurology and the development of novel tools for rehabilitation, results from more and more clinical trials are now available, thus here justifying conducting a systematic review. Methods and analysis: This systematic review protocol is developed in accordance with the methodology recommended by the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols, as well as the Cochrane handbook for systematic reviews of interventions. Relevant studies will be identified by searching the databases. We will perform searches for relevant studies in databases, including PubMed, Embase, CINAHL, and Web of Science, Physiotherapy Evidence Database and Cochrane Library databases. The reference lists of included articles and reviews will be searched manually. The date range parameters used in searching all databases will be restricted between January 2001 and January 2021. Randomized controlled trials (RCTs) published will be included. The language used in the articles included was restricted to English. The GRADE (Grading of Recommendations, Assessment, Development and Evaluation system from the Cochrane Handbook for Systematic Reviews of Interventions) approach will be used to systematically appraise the quality of methodology. We will assess the risk of bias of the RCTs included using the Cochrane Collaboration’s tool and provide a qualitative synthesis. After that, we will consider conducting a meta-analysis if the final data across outcomes shows sufficient homogeneity. Ethics and dissemination: No ethical approval is needed as the proposed study does not involve the collection of primary data, and the results of this review will be disseminated via peer-reviewed publications and conference presentations. Trial registration number: CRD42021267069.

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Patients’ and psychiatrists’ perspectives on clozapine treatment—a scoping review protocol

BMJ Open ◽

10.1136/bmjopen-2021-054308 ◽

2021 ◽

Vol 11 (10) ◽

pp. e054308

Author(s):

Michelle Iris Jakobsen ◽

Ole Jakob Storebø ◽

Stephen Fitzgerald Austin ◽

Jimmi Nielsen ◽

Erik Simonsen

Keyword(s):

Scoping Review ◽

Qualitative Content Analysis ◽

Patient Perspectives ◽

Current Evidence ◽

Cochrane Library ◽

Future Research ◽

Clozapine Treatment ◽

Primary Literature ◽

Conference Presentations ◽

Review Protocol

IntroductionThe atypical antipsychotic clozapine has shown superior efficacy compared with other antipsychotics and is the gold standard for treating otherwise treatment resistant schizophrenia. However, multiple studies have found that clozapine is underutilised in most parts of the world. A few reviews of literature addressing barriers to clozapine prescribing have been conducted. While there is some variation in the literature included in these reviews, a common feature of the studies included is that they primarily focus on clinical staff’s attitudes and perceived barriers for prescribing. Studies of patient perspectives are only sparsely included. A preliminary literature search revealed though, that additional literature on the subject exists, including literature on patient perspectives. It is therefore difficult to conclude if the formerly synthesised literature is representative of current evidence or if the topic has been adequately investigated to inform clinical practice. A scoping review is warranted in order to map and synthesise primary literature on patients’ and psychiatrists’ perspectives on clozapine treatment, and to identify gaps for future research.Methods and analysisThe electronic databases Cochrane Library, CINAHL, Web of Science, Psychinfo, MEDLINE and EMBASE will be searched for relevant publications, supplied with searches of Google scholar, The Networked Digital Library of Theses and Dissertations and OpenGrey. Citation tracking of selected studies will furthermore be undertaken. Two researchers will independently screen and extract data. Data will be collated to provide a descriptive summary of the literature, along with a qualitative content analysis of key findings. Identified gaps in research will be accompanied by recommendations for future investigations.Ethics and disseminationFindings will be disseminated through a peer-reviewed journal and conference presentations. The scoping review does not require ethics approval.

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Mapping Evidence on Global Perceptions of Environmental Sustainability amidst the COVID-19 Pandemic: A Systematic Review Protocol

10.21203/rs.3.rs-148450/v1 ◽

2021 ◽

Author(s):

PETER ANSU-MENSAH ◽

Monica Ansu-Mensah ◽

Desmond Kuupiel

Keyword(s):

Scoping Review ◽

Environmental Sustainability ◽

Data Extraction ◽

Meta Analysis ◽

World Health ◽

Future Research ◽

Regulatory Bodies ◽

Review Protocol ◽

Government Websites ◽

Health Organization

Abstract Background: Identifying and addressing research gaps on environmental sustainability in this striving time of COVID-19, it is imperative to ensure proper waste management disposal, efficient use of energy as well as judicious use of transport in order to achieve the SDGs 2030.Aim: The proposed scoping review is aimed at mapping evidence on global perceptions of environmental sustainability amidst COVID-19 pandemic. Methods: The proposed study will be guided by the enhanced version of Arksey and O’Malley’s scoping review framework, and Levac et al. 2010 recommendations together with the 2015 Joanna Briggs Institute guidelines. A comprehensive keywords search for relevant studies presenting evidence of environmental sustainability during COVID-19 pandemic will be conducted with the following databases: SCOPUS, Google Scholar, EBSCOhost, and PubMed. Literature from university repositories and international organization such as the World Health Organization (WHO) and government websites relevant to the proposed study will also be retrieved. The proposed review will use the Preferred Reporting Items for Systematic Reviews and Meta-analysis: Extension for Scoping Review (PRISMA-ScR) to present the results of the study. For data extraction in a content thematic manner of analysis, NVivo version 11 software package will be used. A mixed methods appraisal tool (MMAT) version 2018 will be employed to appraise the quality of all the included studies. Discussion: We are hopeful that the results of the proposed study will inform future research and unveil evidence-based information to report potential environmental sustainability issues that may arise in this new phase of COVID-19 pandemic. It also anticipated that the proposed study will enable policy and regulatory bodies to implement new strategies to achieve the SDGs inclusive of COVID-19 pandemic.

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Exploration of stress management interventions to address psychological stress in stroke survivors: a protocol for a scoping review

BMJ Open ◽

10.1136/bmjopen-2019-035592 ◽

2020 ◽

Vol 10 (3) ◽

pp. e035592

Author(s):

Madeleine Hinwood ◽

Marina Ilicic ◽

Prajwal Gyawali ◽

Murielle Gabriela Kluge ◽

Kirsten Coupland ◽

...

Keyword(s):

Stress Management ◽

Scoping Review ◽

Cochrane Library ◽

Future Research ◽

Stroke Survivors ◽

Brain Repair ◽

Management Interventions ◽

Study Selection ◽

Research Findings ◽

Research Questions

IntroductionSeveral studies have shown that stroke survivors report experiencing high and unremitting levels of stress, which can negatively affect brain repair processes and psychological outcomes and thereby compromise recovery. However, it is presently unclear which interventions have been trialled to manage stress in stroke survivors and whether they translate to clinically relevant outcomes. The aim of this scoping review will be to examine stress management interventions in stroke survivors in order to map the types of interventions trialled, commonly reported stress outcome measures and whether a reduction in stress contributes to reductions in relevant clinical outcomes.Methods and analysisThe methodological framework described in Arksey and O’Malley will be applied to this review. A draft search strategy was developed in collaboration with an experienced senior health research librarian. A systematic search of Medline, Embase, CINAHL, Cochrane library, PsycInfo and Clinicaltrials.gov as well as hand searching of reference lists and reviews will identify relevant studies for inclusion. To be eligible for inclusion, studies must report on the outcomes of an intervention targeting stress management and resilience in stroke survivors. Study selection and critical appraisal of selected studies will be carried out independently by two authors, with discrepancies resolved by consensus. Data will be charted using a standard extraction form. Results will be tabulated and narratively summarised to highlight findings relevant to our research questions and to inform recommendations for future research.Ethics and disseminationThis study does not require ethics approval. This scoping review will provide a synthesis of evidence for stress management interventions in stroke survivors. It will identify and clarify the gaps in stress research specific to stroke pathologies and highlight promising interventions for future research. Findings will be relevant to researchers and healthcare workers and will be disseminated via publications in peer-reviewed journals and presented at conferences.

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Adolescent undernutrition in South Asia: a scoping review protocol

BMJ Open ◽

10.1136/bmjopen-2019-031955 ◽

2020 ◽

Vol 10 (1) ◽

pp. e031955

Author(s):

Sara Estecha Querol ◽

Lena Al-Khudairy ◽

Romaina Iqbal ◽

Samantha Johnson ◽

Paramjit Gill

Keyword(s):

South Asia ◽

Scoping Review ◽

Grey Literature ◽

Research Priorities ◽

Cochrane Library ◽

Bibliographic Databases ◽

Future Research ◽

Eligibility Criteria ◽

Ethical Approval ◽

Review Protocol

IntroductionThe aim of the protocol is to present the methodology of a scoping review that aims to synthesise up-to-date evidence on adolescent undernutrition in South Asia.Methods and analysisThe proposed scoping review will be guided by Arksey and O’Malley’s framework and the Joanna Briggs Institute Reviewers’ Manual. The scoping review question, eligibility criteria and search strategy will be based on the Population, Concept and Context strategy. We will conduct the search in electronic bibliographic databases (Medline (OVID), Embase, Cochrane Library, Web of Science, CINAHL, PsycInfo, Scopus) as well as various grey literature sources in order to synthesise and present the findings with descriptive statistics and a narrative description of both quantitative and qualitative evidence.Ethics and disseminationThis study protocol does not require ethical approval. This protocol will accurately describe the proposed scoping review that will map the evidence on adolescent undernutrition in South Asia. The proposed review aims to gather published and unpublished literature to inform policy and healthcare organisations as well as identify future research priorities in South Asia.

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Establishing how social capital is studied in relation to cardiovascular disease and identifying gaps for future research—A scoping review protocol

PLoS ONE ◽

10.1371/journal.pone.0249751 ◽

2021 ◽

Vol 16 (4) ◽

pp. e0249751

Author(s):

Marie Parker ◽

Xiangming Fang ◽

Shannon Renee Self-Brown ◽

Ali Rahimi

Keyword(s):

Cardiovascular Disease ◽

Social Capital ◽

Scoping Review ◽

Research Question ◽

Evidence Base ◽

Future Research ◽

Review Protocol ◽

Research Questions ◽

Meta Analyses ◽

The Relationship

Introduction Though the relationship between social capital and health has been widely studied, the evidence of this relationship in cardiovascular disease is limited, with varied and inconsistent measures. This scoping review seeks to address this gap by answering the following questions: (1) How has social capital been characterized and measured in the literature related to cardiovascular disease? and (2) What gaps exist in the evaluation of the relationship between social capital and cardiovascular disease? Materials and methods A scoping review will be used to answer the research questions. The scoping review will apply established methods described by Arksey and O’Malley, Levac and colleagues, and the Joanne Briggs Institute: (1) identifying the research question(s); (2) identifying relevant studies; (3) selecting the studies; (4) charting the data; and (5) collating, summarizing, and reporting the results. Results Our findings will be reported in accordance with the guidance provided in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols (PRISMA-P) statement. Discussion The synthesis of this evidence base is intended to provide a framework for how social capital has been defined and measured in the cardiovascular literature, with additional guidance for future research and evaluation. The findings will be disseminated through peer-reviewed publication and presentations at relevant seminars.

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How we teach children with asthma to use their inhaler: A scoping review protocol

10.21203/rs.3.rs-20630/v3 ◽

2020 ◽

Author(s):

Patrick McCrossan ◽

Orla Mallon ◽

Michael Shields ◽

Dara O'Donoghue

Keyword(s):

Scoping Review ◽

Cochrane Library ◽

Future Research ◽

Inhaler Technique ◽

Case Control Studies ◽

Quantitative Studies ◽

Children With Asthma ◽

Review Protocol ◽

Randomised Controlled ◽

The Cochrane Library

Abstract Background One reason that asthma remains poorly controlled in children is poor inhaler technique. Current guidelines recommend checking inhaler technique at each clinical visit. However, they do not specify how best to train children to mastery of correct inhaler technique. Currently many children are simply shown how to use inhalers (brief intervention) which results in less than 50% with correct inhaler technique. The aim of this scoping review is to explore published literature on teaching methods used to train children to master correct inhaler technique.Methods This scoping review will follow the Arksey and O'Malley framework and the Joanna Briggs Institute guidelines. We will search (from inception onwards): MEDLINE, Embase, Scopus, Web of Science, CINAHL and the Cochrane library. We will include quantitative studies, (e.g. randomised controlled trials, cohort studies and case-control studies), published from the year 1956 to present, on teaching the skill of inhaler technique to children with asthma. Two reviewers will complete all screening and data abstraction independently. Data will be extracted onto a data charting table to create a descriptive summary of the results. Data will then be synthesised with descriptive statistics and visual mapping.Discussion This scoping review will provide a broad overview of currently used educational methods to improve inhaler technique in children with asthma. The analysis will allow us to refine future research in this area by focusing on the most effective methods and optimising them.

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The use of mechanical insufflation-exsufflation in invasively ventilated critically ill adults: a scoping review protocol

Systematic Reviews ◽

10.1186/s13643-020-01547-8 ◽

2020 ◽

Vol 9 (1) ◽

Author(s):

Ema Swingwood ◽

Willemke Stilma ◽

Lyvonne Tume ◽

Fiona Cramp ◽

Frederique Paulus ◽

...

Keyword(s):

Critically Ill ◽

Scoping Review ◽

Adult Patients ◽

Barriers And Facilitators ◽

Cochrane Library ◽

Future Research ◽

Safety And Efficacy ◽

Research Questions ◽

Critically Ill Adults ◽

Ill Adults

Abstract Background Critically ill patients receiving invasive ventilation are at risk of sputum retention. Mechanical insufflation-exsufflation (MI-E) is a technique used to mobilise sputum and optimise airway clearance. Recently, interest has increased in the use of mechanical insufflation-exsufflation for invasively ventilated critically ill adults, but evidence for the feasibility, safety and efficacy of this treatment is sparse. The aim of this scoping review is to map current and emerging evidence on the feasibility, safety and efficacy of MI-E for invasively ventilated adult patients with the aim of highlighting knowledge gaps and identifying areas for future research. Specific research questions aim to identify information informing indications and contraindications to the use of MI-E in the invasively ventilated adult, MI-E settings used, outcome measures reported within studies, adverse effects reported and perceived barriers and facilitators to using MI-E reported. Methods We will search electronic databases MEDLINE, EMBASE, CINAHL using the OVID platform, PROSPERO, The Cochrane Library, ISI Web of Science and the International Clinical Trials Registry Platform. Two authors will independently screen citations, extract data and evaluate risk of bias using the Mixed Methods Appraisal Tool. Studies included will present original data and describe MI-E in invasively ventilated adult patients from 1990 onwards. Our exclusion criteria are studies in a paediatric population, editorial pieces or letters and animal or bench studies. Search results will be presented in a PRISMA study flow diagram. Descriptive statistics will be used to summarise quantitative data. For qualitative data relating to barriers and facilitators, we will use content analysis and the Theoretical Domains Framework (TDF) as a conceptual framework. Additional tables and relevant figures will present data addressing our research questions. Discussion Our findings will enable us to map current and emerging evidence on the feasibility, safety and efficacy of MI-E for invasively ventilated critically ill adult patients. These data will provide description of how the technique is currently used, support healthcare professionals in their clinical decision making and highlight areas for future research in this important clinical area. Systematic review registration Open Science Framework submitted on 9 July 2020. https://osf.io/mpksq/.

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