scholarly journals Association Between the Blautia/Bacteroides Ratio and Altered Body Mass Index After Bariatric Surgery

2021 ◽  
Author(s):  
Yoonhong Kim ◽  
Doo Heon Son ◽  
Sanghyun Lim ◽  
Bu Kyung Kim ◽  
Ki Hyun Kim ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Body Mass Index ◽  
Gut Microbiota ◽  
Healthy Volunteers ◽  
Body Mass ◽  
Potential Role ◽  
Current Evidence ◽  
Obese Patients ◽  
Positive Correlation ◽  
Before And After

Abstract Current evidence support that the gut microbiota plays a potential role in obesity. Bariatric surgery can reduce excess weight and decrease the risk of life-threatening weight-related health problems and may also influence gut microbiota. In this study, we aimed to investigate the changes in gut microbiota before and after bariatric surgery and evaluate the association of the gut microbial shift and altered body mass index (BMI) after bariatric surgery. Between January 2019 and July 2020, stools from 58 patients scheduled for bariatric surgery were collected. Six months after bariatric surgery, stools from 22 of these patients were re-collected, and the changes in gut microbiota before and after bariatric surgery were evaluated. In addition, the differences in gut microbiota between patients with severe obesity (BMI > 35, n=42) and healthy volunteers with normal BMI (18.8 – 22.8, n=41) were investigated. The gut microbiota of patients who underwent bariatric surgery showed increased α-diversity and differed β-diversity compared with those before surgery. Interestingly, Blautia was decreased and Bacteriodes was increased at the genus level after bariatric surgery. Further, the Blautia/Bacteroides ratio showed a positive correlation with BMI. These results were similar regardless of the surgery type (Roux-en-Y gastric bypass or sleeve gastrectomy). To validate these results, we compared the gut microbiota from severely obese patients with high BMI with those from healthy volunteers and demonstrated that the Blautia/Bacteroides ratio correlated positively with BMI. In the gut microbial analysis of patients who underwent bariatric surgery, we identified that the Blautia/Bacteroides ratio had changed after bariatric surgery and showed a positive correlation with BMI. Based on these results, we suggest that bariatric surgery could change the gut microbiota and specific microbiomes might have a potential role in obese patients.

scholarly journals Reevaluation of the Airways of Obese Patients Undergone Bariatric Surgery after Reduction in Body Mass Index

2011 ◽  
Vol 61 (1) ◽  
pp. 31-40 ◽  
Author(s):  
José Admirço Lima Filho ◽  
Eliana Marisa Ganem ◽  
Bruno Gardélio Pedreira de Cerqueira
Keyword(s):  
Bariatric Surgery ◽  
Body Mass Index ◽  
Body Mass ◽  
Obese Patients

scholarly journals The Role of Sleeve Gastrectomy on Preventing Type 2 Diabetes Mellitus

2017 ◽  
Vol 5 (3) ◽  
pp. 316-318 ◽  
Author(s):  
Serdar Olt ◽  
Sabri ÖzdaÅŸ ◽  
Mehmet Åžirik
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Bariatric Surgery ◽  
Body Mass Index ◽  
Type 2 Diabetes Mellitus ◽  
Body Mass ◽  
P Value ◽  
Obese Patients ◽  
The Mean

AIM: To investigate the effect of bariatric surgery on HbA1c and serum cortisol levels in morbidly obese patients without type 2 diabetes mellitus.MATERIALS AND METHODS: Twenty-nine patients who underwent sleeve gastrectomy and whose body mass index was> 40 were included in the present study. Patients' files were reviewed retrospectively. Those with diabetes mellitus and those with age <18 were excluded from the study. Pre-operative and 1-year post operative data were documented. The obtained data were analysed by SPSS statistical program.RESULTS: The mean age of the patients was 27.4 ± 8.4. 5 of the patients were male, and 24 were female. The mean body mass index of the patients was 44 ± 2.3. 1 patient [3.4%] had hypertension. Four patients [13.7%] had gastroesophageal reflux disease. The number of smokers was 7 [24.1%], and the number of alcohol users was 3 [10.3%]. There was a statistically significant decrease in HbA1c, body mass index values after operation [p value <0.01], but cortisol was not different [p value = 0.72].CONCLUSION: In this present study we found that bariatric surgery caused a significant decrease in HbA1c levels in non-diabetic patients, suggesting that bariatric surgery may prevent Type 2 Diabetes Mellitus in obese patients.

Bariatric surgery for the treatment of idiopathic intracranial hypertension

2011 ◽  
Vol 114 (1) ◽  
pp. 34-39 ◽  
Author(s):  
Jared Fridley ◽  
Rod Foroozan ◽  
Vadim Sherman ◽  
Mary L. Brandt ◽  
Daniel Yoshor
Keyword(s):  
Bariatric Surgery ◽  
Body Mass Index ◽  
Weight Loss ◽  
Visual Field ◽  
Intracranial Hypertension ◽  
Body Mass ◽  
Idiopathic Intracranial Hypertension ◽  
Obese Patients ◽  
Symptom Resolution ◽  
Visual Field Deficits

Object The purpose of this study was to review the literature on the effectiveness of bariatric surgery for obese patients with idiopathic intracranial hypertension (IIH) with regard to both symptom resolution and resolution of visual deficits. Methods The published literature was reviewed using manual and electronic search techniques. Data from each relevant manuscript were gathered, analyzed, and compared. These included demographic data, pre- and postoperative symptoms, pre- and postoperative visual field deficits, bariatric procedure type, absolute weight loss, changes in body mass index, and changes in CSF opening pressure. Results Eleven relevant publications (including 6 individual case reports) were found, reporting on a total of 62 patients. The Roux-en-Y gastric bypass was the most common bariatric procedure performed. Fifty-six (92%) of 61 patients with recorded postoperative clinical history had resolution of their presenting IIH symptoms following bariatric surgery. Thirty-four (97%) of 35 patients who had undergone pre- and postoperative funduscopy were found to have resolution of papilledema postoperatively. Eleven (92%) of 12 patients who had undergone pre- and postoperative formal visual field testing had complete or nearly complete resolution of visual field deficits, and the remaining patient had stabilization of previously progressive vision loss. In 13 patients both pre- and postoperative CSF pressures were recorded, with an average postoperative pressure decrease of 254 mm H2O. Changes in weight loss and body mass index varied depending on the reported postoperative follow-up interval. Conclusions The published Class IV evidence suggests that bariatric surgery may be an effective treatment for IIH in obese patients, both in terms of symptom resolution and visual outcome. Prospective, controlled studies are necessary for better elucidation of its role.

scholarly journals PREVALENCE OF JOINT PAIN AND OSTEOARTHRITIS IN OBESE BRAZILIAN POPULATION

2018 ◽  
Vol 31 (1) ◽  
Author(s):  
Daniel Moreira PACCA ◽  
Gustavo Constantino DE-CAMPOS ◽  
Alessandro Rozin ZORZI ◽  
Elinton Adami CHAIM ◽  
Jõao Batista DE-MIRANDA
Keyword(s):  
Bariatric Surgery ◽  
Body Mass Index ◽  
Knee Osteoarthritis ◽  
Body Mass ◽  
Joint Pain ◽  
Hip Osteoarthritis ◽  
High Body Mass Index ◽  
Morbidly Obese ◽  
Obese Patients ◽  
X Rays

ABSTRACT Background: High body mass index, as well as maintaining this condition for a long period of time, are important risk factors for the development of osteoarthritis. Aim: To determine joint pain and osteoarthritis prevalence in patients referred to bariatric surgery. Methods: Morbidly obese patients referred to bariatric surgery responded to the visual analogue pain scale (VAS) and the WOMAC questionnaire. X-rays of the hips and knees were evaluated. The primary endpoints were self-reported joint pain and the diagnosis of osteoarthritis by clinical and radiological criteria of the American College of Rheumatology. Results: 141 patients were interviewed (85.1% women) with a mean age of 40 years. The mean body mass index was 46. The lumbar spine and knee joint were the most commonly reported as painful (77.9% and 73.2% respectively). Prevalence of knee osteoarthritis was 63.1% and hip osteoarthritis was 40.8%. Age, mean VAS and WOMAC scores were higher in the osteoarthritic individuals. Conclusion: There is prevalence of 90.1% of pain symptoms in morbidly obese patients referred to bariatric surgery. The prevalence of knee osteoarthritis was 63.1% and hip osteoarthritis was 40.8% in this sample.

scholarly journals MO181ULTRASOUND ASSESSMENT OF KIDNEY SIZE AND ITS CORRELATION WITH BODY MASS INDEX IN HEALTHY VOLUNTEERS WITHOUT RENAL DISEASE

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Nazma Mohammed ◽  
Muzamil Latief ◽  
Manzoor Parry ◽  
Manjusha Yadla
Keyword(s):  
Body Mass Index ◽  
Healthy Volunteers ◽  
Body Mass ◽  
Cortical Thickness ◽  
Left Kidney ◽  
Kidney Size ◽  
Positive Correlation ◽  
Kidney Length ◽  
Study Population ◽  
Renal Length

Abstract Background and Aims Renal length as well as renal cortical thickness has been closely related to creatinine clearance in patients with chronic kidney disease. Our primary aim was to establish a normal range of values for kidney length in our adult population with normal renal function. Method This was a prospective observational study. Ultrasonographic assessment of renal parameters in 499 healthy volunteers between 18 to 80 years of age was done. Volunteers with any known renal condition or any co-morbidity were excluded from the study population. Correlation between body mass index (BMI) and renal parameters was assessed. Results Out of 499 volunteers 327 (65%) were males and 172(35%) were females. 17.8% volunteers were less than 30 years of age, 51.5% volunteers were in the age group of 30-60 years and 30.7 % were above 60 years of age. Mean BMI in males was 25.20 ± 3.96 kg/m2 whereas mean BMI in females was 24.08 ± 3.28 kg/m2. In males the mean cortical thickness in right kidney was 13.68+/- 2.47 mm and in left kidney cortical thickness was 13.94 ± 2.6 mm. In females right kidney cortical thickness was 12.63 ± 1.91 mm and left kidney cortical thickness was 13.40 ± 2.37 mm. In the present study the right mean renal length was 9.9 ± 40cm and left renal length was 10.19 ± 0.97cm. In our study, there was positive correlation BMI with renal length. Conclusion Size of kidney has significant ethnic and geographic basis and there is a positive correlation between BMI and kidney size in our study population.

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