scholarly journals Trajectories of Key Physiological Parameters in COVID-19 Patients Using Continuous Remote Monitoring and Health AI

2020 ◽  
Author(s):  
Arik Eisenkraft ◽  
Yasmin Maor ◽  
Keren Constantini ◽  
Nir Goldstein ◽  
Dean Nachman ◽  
...  
Keyword(s):  
Remote Monitoring ◽  
Vital Signs ◽  
Blood Oxygen ◽  
Cardiorespiratory System ◽  
Blood Oxygen Saturation ◽  
Frequent Monitoring ◽  
Respiratory Parameters ◽  
Multi Center Study ◽  
First Time ◽  
Worse Prognosis

Abstract Coronavirus disease 2019 (COVID-19) exerts deleterious effects on the cardiorespiratory system, leading to worse prognosis in the most effected. The aim of this retrospective multi-center study was to describe the variability of key cardiopulmonary vitals amongst hospitalized COVID-19 patients, measured every 15 minutes using a novel wearable chest-monitor. A total of 492 patients were included, with >3 million measurements collected including heart rate, systolic and diastolic blood pressure, cardiac output, cardiac index, systemic vascular resistance, respiratory rate, blood oxygen saturation, and body temperature. We show differential trajectories of these vital signs, apparent within the first 24hrs of monitoring. Importantly, we show for the first time that cardiovascular deterioration appears early after admission and in parallel with changes in the respiratory parameters, and identify sub-populations at high risk. Combining frequent monitoring using wearable technology with advanced big data and AI analysis tools may aid early detection of deterioration of COVID-19 patients.

scholarly journals Continuous Remote Patient Monitoring Shows Early Cardiovascular Changes in COVID-19 Patients

2021 ◽  
Vol 10 (18) ◽  
pp. 4218
Author(s):  
Arik Eisenkraft ◽  
Yasmin Maor ◽  
Keren Constantini ◽  
Nir Goldstein ◽  
Dean Nachman ◽  
...  
Keyword(s):  
Patient Monitoring ◽  
Vital Signs ◽  
Final Analysis ◽  
Remote Patient Monitoring ◽  
Blood Oxygen Saturation ◽  
Respiratory Parameters ◽  
Significant Difference ◽  
Observational Cohort ◽  
Remote Patient ◽  
Worse Prognosis

COVID-19 exerts deleterious cardiopulmonary effects, leading to a worse prognosis in the most affected. This retrospective multi-center observational cohort study aimed to analyze the trajectories of key vitals amongst hospitalized COVID-19 patients using a chest-patch wearable providing continuous remote patient monitoring of numerous vital signs. The study was conducted in five COVID-19 isolation units. A total of 492 COVID-19 patients were included in the final analysis. Physiological parameters were measured every 15 min. More than 3 million measurements were collected including heart rate, systolic and diastolic blood pressure, cardiac output, cardiac index, systemic vascular resistance, respiratory rate, blood oxygen saturation, and body temperature. Cardiovascular deterioration appeared early after admission and in parallel with changes in the respiratory parameters, showing a significant difference in trajectories within sub-populations at high risk. Early detection of cardiovascular deterioration of COVID-19 patients is achievable when using frequent remote patient monitoring.

Order effect when comparing usability of two telehealth remote monitoring technology solutions

2018 ◽  
Vol 7 (1) ◽  
pp. 148-151
Author(s):  
Juuso Leinonen ◽  
Erin Sparnon ◽  
Patrice Tremoulet
Keyword(s):  
Remote Monitoring ◽  
Index Finger ◽  
Order Effect ◽  
Personal Health ◽  
Blood Oxygen ◽  
Technology Evaluation ◽  
Blood Oxygen Saturation ◽  
System Usability Scale ◽  
Within Subjects ◽  
Pulse Oximeters

An experienced healthcare device evaluator collaborated with a human factors scientist to develop and conduct a usability test of two different telehealth remote monitoring solutions as part of a larger technology evaluation. Twenty-one participants used each of the telehealth platforms to capture and transmit data. Typically users of telehealth platforms capture and send their own data, however, we asked our participants to place a bag of sand on wirelessly connected scales to capture weight information and to place the wireless pulse oximeters on the healthcare device evaluator’s index finger to get blood oxygen saturation measurements. This protocol enabled participants to go through the processes required to capture and share representative data without providing any of their own personal health data. After using each solution to complete the same series of three tasks, participants filled out the System Usability Scale (SUS) questionnaire. We intended to compare SUS scores within-subjects, but discovered that the SUS scores for the second solution were not independent. In particular, the participants who used the system that was harder to use second produced SUS scores for that system that were significantly lower than the participants who rated that system first. We conclude that it may not be appropriate to use a within-subjects design if experimenters plan to compare the SUS scores for different systems.

scholarly journals Clinical, Demographic, and Epidemiological Characteristics of Patients Diagnosed with COVID-19 in Zahedan, Southeastern Iran

2021 ◽  
Vol 18 (4) ◽  
Author(s):  
Behzad Shahi ◽  
Faeze Kazemi ◽  
Shahaboddin Mashaei ◽  
Mahdi Foroughian ◽  
Maryam Ziaei ◽  
...  
Keyword(s):  
Vital Signs ◽  
Descriptive Study ◽  
Descriptive Statistics ◽  
Health Centers ◽  
Blood Oxygen ◽  
Shortness Of Breath ◽  
Abo Blood Groups ◽  
Rt Pcr ◽  
Blood Oxygen Saturation ◽  
Epidemiological Characteristics

: As the epidemic spreads, COVID-19 poses a severe threat to the health of communities. Description of epidemiological characteristics of COVID-19 patients helps with the prevention and scientific control of the pandemic. This descriptive study was conducted to describe the clinical, demographic, and epidemiological characteristics of 65 patients suspected of having COVID-19. A research-made questionnaire was used for data collection. Moreover, the patient's vital signs were examined. The samples were classified into the two groups of subjects with positive and negative RT-PCR test. Descriptive statistics were used for the analysis of data. The most common manifestations were fever, shortness of breath, and dry cough. Moreover, the lowest proportion belonged to Rh-negative in all ABO blood groups. The patients were mainly male, about 44 years old, and their first and most common manifestations were fever, shortness of breath, and dry cough. In vital signs examination, reduction of blood oxygen saturation was the most important finding. Health centers need to consider these signs in treating COVID-19 patients.

scholarly journals Comparing the Effects of Suction and Routine Methods on Vital Signs, Arterial Blood Oxygen Saturation and Pain Level of Patients Hospitalized at the Intensive Care Unit

2016 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Aliakbar Keykha ◽  
Hasan Askari ◽  
Abbas Abbaszadeh ◽  
Hasan Enayatie ◽  
Bibi Mahdie Khodadadi Hosini ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Oxygen Saturation ◽  
Vital Signs ◽  
Blood Oxygen ◽  
Pain Level ◽  
Blood Oxygen Saturation ◽  
Arterial Blood ◽  
Arterial Blood Oxygen

scholarly journals A Comparison of Reflective Photoplethysmography for Detection of Heart Rate, Blood Oxygen Saturation, and Respiration Rate at Various Anatomical Locations

Sensors ◽  
2019 ◽  
Vol 19 (8) ◽  
pp. 1874 ◽  
Author(s):  
Sally K. Longmore ◽  
Gough Y. Lui ◽  
Ganesh Naik ◽  
Paul P. Breen ◽  
Bin Jalaludin ◽  
...  
Keyword(s):  
Heart Rate ◽  
Oxygen Saturation ◽  
Respiration Rate ◽  
Vital Signs ◽  
Ground Truth ◽  
Human Anatomy ◽  
Anatomical Location ◽  
Blood Oxygen ◽  
Blood Oxygen Saturation ◽  
Multiple Sensors

Monitoring of vital signs is critical for patient triage and management. Principal assessments of patient conditions include respiratory rate heart/pulse rate and blood oxygen saturation. However, these assessments are usually carried out with multiple sensors placed in different body locations. The aim of this paper is to identify a single location on the human anatomy whereby a single 1 cm × 1 cm non-invasive sensor could simultaneously measure heart rate (HR), blood oxygen saturation (SpO2), and respiration rate (RR), at rest and while walking. To evaluate the best anatomical location, we analytically compared eight anatomical locations for photoplethysmography (PPG) sensors simultaneously acquired by a single microprocessor at rest and while walking, with a comparison to a commercial pulse oximeter and respiration rate ground truth. Our results show that the forehead produced the most accurate results for HR and SpO2 both at rest and walking, however, it had poor RR results. The finger recorded similar results for HR and SpO2, however, it had more accurate RR results. Overall, we found the finger to be the best location for measurement of all three parameters at rest; however, no site was identified as capable of measuring all parameters while walking.

scholarly journals Design Implementation and Evaluation of a Mobile Continuous Blood Oxygen Saturation Monitoring System

Sensors ◽  
2020 ◽  
Vol 20 (22) ◽  
pp. 6581
Author(s):  
Qingxue Zhang ◽  
David Arney ◽  
Julian M. Goldman ◽  
Eric M. Isselbacher ◽  
Antonis A. Armoundas
Keyword(s):  
Oxygen Saturation ◽  
Model Building ◽  
Nonlinear Models ◽  
Human Subjects ◽  
Design Principles ◽  
Blood Oxygen ◽  
Calculation Methods ◽  
Blood Oxygen Saturation ◽  
First Time ◽  
Health Monitor

Objective: In this study, we built a mobile continuous Blood Oxygen Saturation (SpO2) monitor, and for the first time, explored key design principles towards daily applications. Methods: We firstly built a customized wearable computer that can sense two-channel photoplethysmogram (PPG) signals, and transmit the signals wirelessly to smartphone. Afterwards, we explored many SpO2 model building principles, focusing on linear/nonlinear models, different PPG parameter calculation methods, and different finger types. Moreover, we further compared PPG sensor placement principles by comparing different hand configurations and different finger configurations. Finally, a dataset collected from eleven human subjects was used to evaluate the mobile health monitor and explore all of the above design principles. Results: The experimental results show that the root mean square error of the SpO2 estimation is only 1.8, indicating the effectiveness of the system. Conclusion: These results indicate the effectiveness of the customized mobile SpO2 monitor and the selected design principles. Significance: This research is expected to facilitate the continuous SpO2 monitoring of patients with clinical indications.

scholarly journals Wearable Sensors for Monitoring Vital Signs of Patients

2018 ◽  
Vol 7 (2.11) ◽  
pp. 62 ◽  
Author(s):  
Parminder Kaur ◽  
Hardeep Singh Saini ◽  
Bikrampal Kaur
Keyword(s):  
Pressure Pulse ◽  
Medical Condition ◽  
Wearable Sensors ◽  
Vital Signs ◽  
Blood Oxygen ◽  
New Disease ◽  
State Of Health ◽  
Blood Oxygen Saturation ◽  
Normal Ranges ◽  
Vital Parameters

Vital signs of a person are the indicator of basic bodily functions and provide critical information for accessing a patient's state of health. The four Vital signs are: Blood Pressure, Pulse Rate, Body temperature and Respiration Rate. In some cases, blood oxygen saturation is also measured. Vital signs help in identifying an already existing medical condition, diagnosing new disease and can also be very helpful in providing critical care to patients in time of emergency. Traditional ways of Vital sign monitoring are being replaced by more technical methods employing the use of wearable sensors. Not only are wearable sensors an aid for getting vital signs accurately but a multitude of parameters can be obtained by using an assembly of wearable sensors. With the help of wearable sensors, telemonitoring of patients has become a reality. This paper discusses the Vital parameters, their normal ranges and different wearable sensors to measure these parameters.  

scholarly journals Monitoring of Cardiorespiratory Parameters in Rats—Validation Based on Pharmacological Stimulation

2021 ◽  
Vol 14 (12) ◽  
pp. 1223
Author(s):  
Joanna Miklosz ◽  
Bartlomiej Kalaska ◽  
Stanislaw Zajaczkowski ◽  
Dariusz Pawlak ◽  
Andrzej Mogielnicki
Keyword(s):  
Blood Pressure ◽  
Body Temperature ◽  
Oxygen Saturation ◽  
Respiratory Rate ◽  
Blood Perfusion ◽  
Blood Oxygen ◽  
Blood Oxygen Saturation ◽  
Toxicity Studies ◽  
Respiratory Parameters ◽  
Safety And Toxicity

The methods used in preclinical studies should minimize the suffering and the number of animals but still provide precise and consistent results enabling the introduction of drug candidates into the phase of clinical trials. Thus, we aimed to develop a method allowing us to perform preliminary safety and toxicity studies of candidates for human medicines, while reducing the number of animals. We have devised a method based on a combination of two devices: Plugsys (Transonics System Inc., Ithaca, NY, USA) and PhysioSuite (Kent Scientific Corporation, Torrington, CT, USA), which allow simultaneous registration of nine circulatory and respiratory parameters, and body temperature. Vehicle and adrenaline, or nitroglycerin, as reference substances were administered into the right femoral vein of Wistar rats. Physiological conditions were registered over 60 min after drug administration by measuring systolic, diastolic and mean blood pressure, heart rate (HR), blood perfusion of paw vessels, blood oxygen saturation, respiratory rate, average and peak exhaled CO2, and body temperature. Blood pressure was measured by cannula placed in the left common carotid artery and connected to the pressure transducer (Plugsys). The other parameters were measured by the PhysioSuite. Adrenaline-induced immediate dose-related hypertension and nitroglycerin hypotension were correlated with the change in blood perfusion. They both increased HR. Adrenaline decreased blood oxygen saturation and slightly affected respiratory parameters, while nitroglycerin caused a progressive increase in respiratory rate and a decrease in the peak of exhaled CO2. Our method may become an inseparable part of the preliminary safety and toxicity studies of tested drugs, while being an important step towards improving animal welfare.

scholarly journals Midazolam and Its Effect on Vital Signs and Behavior in Children Under Conscious Sedation in Dentistry

2020 ◽  
pp. S305-S314
Author(s):  
J. VASAKOVA ◽  
J. DUSKOVA ◽  
J. LUNACKOVA ◽  
K. DRAPALOVA ◽  
L. ZUZANKOVA ◽  
...  
Keyword(s):  
Conscious Sedation ◽  
Dental Treatment ◽  
Vital Signs ◽  
Pediatric Dentistry ◽  
Clinical Effects ◽  
Blood Oxygen Saturation ◽  
Arterial Blood ◽  
Clinically Significant ◽  
And Behavior ◽  
First Time

Midazolam is a short acting sedative with small number of adverse effects. Administered orally, it is currently the most common form of conscious sedation in children. The objective of this paper is to describe effect of midazolam administered to children during dental treatment on their vital signs, and to monitor changes in children’s behavior. We described values of vital signs and behavior in 418 sedations conducted in 272 children between 1-12 years of age. To achieve the following results, we used data from 272 all first-time sedations. After administration of midazolam arterial blood pressure and blood oxygen saturation decreased by values which were not clinically significant. The heart rate increased, with values staying within the limits of physiological range. The speed of onset of midazolam’s clinical effects depends on age and dose. The lower age and dose correlated with the higher behavior score. The effectiveness of midazolam treatment is 97.8 %. Unwillingness of child to receive midazolam is predictor for disruptive behavior during sedation. 1.8 % of all sedation cases showed paradoxical reactions. The administration of midazolam in dose of 0.5 mg per 1 kg of child’s body weight is safe and could be recommended for dental treatment in pediatric dentistry.

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