A Misdiagnosis of a Huge Lung Fibroleiomyomatous Hamartoma in Pleural Cavity

Abstract Backgroud: Lung fibroleiomyomatous hamartoma is an extremely rare benign tumor in lung, it belongs to hamartoma. There were only five patients with solitary pulmonary fibroleiomyomatous hamartoma reported in literatures and our case has the largest size of the tumor from lung.Case presentation: Our case is a 36-year woman with a huge mass in pleural cavity. She was once misdiagnosed mediastinal germ cell tumor with pleural effusion through percutaneous lung biopsy in other hospital. After traditional thoracotomy, a huge size of 22 x 18 x 5.5 cm mass was completely dissected and a diagnosis of pulmonary fibroleiomyomatous hamartoma was given by pathology combined with immunohistochemical staining, which showed the positive staining of SMA, Desmin, CD34, BCL2, TTF1, Napsin A, and CK7, and the negative staining of S-100 and Calretinin. The patient recovered well with 40 months following up without recurrence.Conclusions:In our case, we had reported the largest size of lung fibroleiomyomatous hamartoma. The treatment of fibroleiomyomatous hamartoma is completely resected it and have a good prognosis.

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Voluminous Extracardiac Adult Rhabdomyoma of the Neck: A Case Presentation

Case Reports in Surgery ◽

10.1155/2012/984789 ◽

2012 ◽

Vol 2012 ◽

pp. 1-3 ◽

Cited By ~ 4

Author(s):

Riccardo Maglio ◽

Scicchitano Francesco ◽

Magistri Paolo ◽

Valabrega Stefano ◽

D'Angelo Francesco ◽

...

Keyword(s):

Head And Neck ◽

Benign Tumor ◽

The Body ◽

Differential Diagnoses ◽

Mesenchymal Tumors ◽

Adult Type ◽

Case Presentation ◽

Italian Patient ◽

First Case ◽

Rare Benign Tumor

Introduction. Rhabdomyomas of the head and neck are exceptionally rare benign mesenchymal tumors. Rare cases have been reported to involve other sites of the body including the head and neck regions.Case Presentation. We report a case of voluminous extracardiac adult rhabdomyoma affecting adult patients and initially seen as slowly growing, indolent neoplasms. The patient is a seventy-year old male Italian patient.Conclusion. Adult extracardiac rhabdomyoma is a rare benign tumor that may present with symptoms that vary from aerodigestive tract obstruction to remaining asymptomatic for many years. Although histology is very characteristic, several differential diagnoses have to be considered. To our knowledge, this is the first case of voluminous adult-type symptomless rhabdomyoma.

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Mesectodermal Leiomyoma of the Ciliary Body: A Unique Variant of Leiomyoma with Myogenic and Neurogenic Histological Features

International Journal of Surgical Pathology ◽

10.1177/10668969211038694 ◽

2021 ◽

pp. 106689692110386

Author(s):

Osamu Inamori ◽

Hideki Fukuoka ◽

Michiko Nagamine ◽

Chie Sotozono ◽

Eiichi Konishi

Keyword(s):

Malignant Melanoma ◽

Ciliary Body ◽

Benign Tumor ◽

Frozen Section ◽

Smooth Muscle Actin ◽

Japanese Woman ◽

Reproductive Age ◽

Positive Staining ◽

Rare Benign Tumor ◽

Slow Growing

Mesectodermal leiomyoma of the ciliary body is a rare benign tumor, showing both neurogenic and myogenic characteristics. This tumor typically shows predilection for women of reproductive age. Because it is almost impossible to clinically distinguish this tumor from malignant melanoma, unnecessary eye enucleations have been unfortunately performed. Herein, we report a case of mesectodermal leiomyoma of the ciliary body in a young Japanese woman. She was referred to our hospital due to a slow-growing mass in her left iris. A malignant tumor could not be clinically ruled out and surgery with intraoperative pathology consultation was performed. Intraoperative frozen section diagnosis was a benign tumor with neurogenic features, and a simple excision of the tumor was performed. Histologically, the tumor was composed of diffuse growth of spindle cells with fibrillary indistinctive cytoplasm. Immunohistochemical examination showed diffuse positive staining of α-smooth muscle actin, h-caldesmon, calponin, and CD56. Scattered tumor cells were weakly positive for desmin. Neither melanocytic markers nor neural markers except for CD56 were positive. We diagnosed this tumor as mesectodermal leiomyoma. Mesectodermal leiomyoma is rare and often misdiagnosed as malignant melanoma. To avoid overtreatment, a correct preoperative diagnosis is essential.

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Large Brunner’s gland adenoma of the duodenum for almost 10 years

Open Life Sciences ◽

10.1515/biol-2020-0029 ◽

2020 ◽

Vol 15 (1) ◽

pp. 237-240

Author(s):

Bo Yang ◽

Ke Li ◽

Runlan Luo ◽

Zuming Xiong ◽

Lianwei Wang ◽

...

Keyword(s):

Benign Tumor ◽

Accurate Diagnosis ◽

Case Presentation ◽

Brunner's Glands ◽

Gastrointestinal Obstruction ◽

Brunner’S Glands ◽

Rare Benign Tumor ◽

Brunner’S Gland ◽

Brunner's Gland ◽

Upper Gastrointestinal

AbstractBackgroundBrunner’s gland adenoma is a rare benign tumor arising from Brunner’s glands. It is mostly small in size, and patients with this tumor are asymptomatic.Case presentationWe report the case of a 63-year-old woman with upper gastrointestinal obstruction for almost 10 years, who was pathologically diagnosed with large Brunner’s gland adenoma of the duodenum. Postoperatively, no sign of recurrence has been noted until now.ConclusionThis study may help clinicians to understand and provide a more accurate diagnosis of Brunner’s gland adenoma.

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A Rare Benign Tumor in a 14-Year-Old Girl

Case Reports in Nephrology ◽

10.1155/2018/1548283 ◽

2018 ◽

Vol 2018 ◽

pp. 1-4

Author(s):

Meral Hassan Abualjadayel ◽

Osama Y. Safdar ◽

Maysaa Adnan Banjari ◽

Sherif El Desoky ◽

Ghadeer A. Mokhtar ◽

...

Keyword(s):

Benign Tumor ◽

Renal Oncocytoma ◽

Pathology Report ◽

Renal Neoplasm ◽

Case Presentation ◽

Renal Oncocytomas ◽

Rare Benign Tumor ◽

History Of ◽

Tract Infections ◽

Left Flank Pain

Background. Oncocytomas are the second most common benign renal neoplasm but, unfortunately, they are difficult to differentiate from renal cell carcinoma. Renal oncocytomas are rare and have mostly been reported in adults. To our knowledge, this is only the sixth pediatric reported case of renal oncocytoma worldwide. Case Presentation. A 14-year-old Yemeni girl with a recurrent history of urinary tract infections came to our clinic complaining of left flank pain with a frontal headache. Ultrasound showed a 3 cm, well-defined echogenic lesion with mild vascularity. This lesion increased in size on her subsequent follow-ups. Computed tomography showed no intralesional fat, vessels invasion, or enlarged lymph nodes. The patient underwent laparoscopic radical nephrectomy, and a pathology report confirmed the diagnosis of renal oncocytoma. Conclusion and Recommendations. We present the rare occurrence of renal oncocytoma in a pediatric patient and highlight the importance of considering oncocytomas in the diagnosis of a renal mass.

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Primary extradural ectopic orbital Meningioma.

10.32512/jmr.4.1.2021/10.12 ◽

2021 ◽

pp. 10-12

Keyword(s):

Visual Impairment ◽

Recurrence Rate ◽

Benign Tumor ◽

Surgical Excision ◽

Good Prognosis ◽

Complete Surgical Excision ◽

Rare Benign Tumor ◽

Long Time ◽

Diagnostic Difficulties ◽

Orbital Meningioma

Orbital meningioma is a rare benign tumor. However, the existence of ectopic orbital meningiomas was debated for long time and this lesion might be underreported. Complete surgical excision could achieve a good prognosis without visual impairment. The recurrence rate is still considerable. The aim of this report was to highlight the diagnostic difficulties and management characteristics.

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Inflammatory Myofibroblastoma Tumor of Intraocular Ciliary Body: A Case Report and Literature Review

10.21203/rs.3.rs-86928/v1 ◽

2020 ◽

Author(s):

he yu ◽

Nianting Tong ◽

Weiqing Huang ◽

Zhan Yu Zhou

Keyword(s):

Ciliary Body ◽

Rare Case ◽

Positive Staining ◽

Slit Lamp ◽

Ki 67 ◽

Case Presentation ◽

S 100 ◽

Hematoxylin And Eosin ◽

Ciliary Body Tumor ◽

Slit Lamp Biomicroscopy

Abstract Background: IMTs are extremely rare in eyes. This is the first report of a IMT of the ciliary body.Case presentation: A ciliary body tumor was found under slit lamp biomicroscopy in a 55-year-old male first diagnosed with cataract. Then this patient underwent trans-sclera resection via partial lamellar sclerouvectomy and par plans vitrectomy to remove the mass. Hematoxylin and eosin (HE) staining and immunohistochemistry findings showed that the characteristics of the tumor were consistent with inflammatory myofibroblastoma tumor (IMT).Conclusions: we reported a rare case of intraocular IMT, which is confirmed by H&E staining, and IHC positive staining for Vimentin, Desmin and ALK, while negative staining for SMA, S-100, ki-67, CK, CD68, and calponin.

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Intraoral lipoma, surgical approach: A Case report

Journal of Craniomaxillofacial Research ◽

10.18502/jcr.v6i4.3296 ◽

2020 ◽

Author(s):

Farnoosh Razmara ◽

Nima Dehghani ◽

Xaniar Mahmoudi ◽

Mohammad Reza Reshadi ◽

Mahdi Mohammadi

Keyword(s):

Adipose Tissue ◽

Buccal Mucosa ◽

Benign Tumor ◽

Surgical Techniques ◽

Surgical Excision ◽

Occurrence Rate ◽

Common Region ◽

Case Presentation ◽

Rare Benign Tumor ◽

Male Patients

Background: Lipoma is a rare benign tumor that overgrows in oral cavity. Its occurrence rate is about 1-4% with predilection for males rather than females. Lipoma is associated with adipose tissue and is usually seen in major salivary glands, buccal mucosa, and vestibule. Fifty percent of lesions are seen in buccal mucosa. The progressive and aggressive growth of these lesions may interfere with speech and mastication owing to the dimensions and location of the tumor. The lesion basically affects the individuals of 4th to 5th decades. Lipoma is managed by surgical excision using scalpel, laser, or electro-cautery. Case Presentation: This study presents two 63 and 18 years old male patients with lipoma in their buccal mucosa along with their improved situation following the treatment. The treatment included surgical excision of the lesion and suturing the surgical area. Conclusions: The incidence of intraoral lipoma is low and buccal mucosa is the most common region for the occurrence of oral lipoma. Most clinicians suggested surgical techniques as a certain treatment.

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Acinar Cystic Transformation of the Pancreas: A Diagnostic Problem

ACTA MEDICA IRANICA ◽

10.18502/acta.v58i8.4595 ◽

2020 ◽

Author(s):

Mehmet Yildirim ◽

Asuman Argon ◽

Sedat Tan ◽

Ahmet Cekic

Keyword(s):

Benign Tumor ◽

Pancreatic Tissue ◽

Cystic Mass ◽

Positive Staining ◽

Abdominal Symptoms ◽

Rare Benign Tumor ◽

Head Of The Pancreas ◽

Immunohistochemical Studies ◽

Multiple Cysts ◽

Macroscopic Examination

Acinar cystic transformation (ACT) or acinar cell cystadenoma is a rare benign tumor of the pancreas. Their clinical presentation is nonspecific, thus hampering their detection and frequently leading to misdiagnosis. In this report, we present a case of ACT of the pancreas in a 54-year-old man that was vague abdominal symptoms. A magnetic resonance imaging was shown a well-defined cystic mass located in the head of the pancreas, measuring 57×47×23 mm. Our patient was treated by pancreaticoduodenectomy. In the macroscopic examination of the mass, a multicystic lesion was found in cream-colored pancreatic tissue. Histological and immunohistochemical studies examination revealed a cystic mass containing multiple cysts at varying sizes, lined by epithelial cells without atypia and positive staining of CK7, CK8/18, and CK19. A high index of clinical suspicion is required to diagnose this tumor. The surgical approach is to ensure accurate diagnosis and to avoid complications

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An Invasive Hemolymphangioma of the Pancreas in a Young Woman

Combinatorial Chemistry & High Throughput Screening ◽

10.2174/1386207322666190103110747 ◽

2019 ◽

Vol 21 (10) ◽

pp. 798-800 ◽

Cited By ~ 1

Author(s):

Zhijun Zhang ◽

Qinghong Ke ◽

Weiliang Xia ◽

Xiuming Zhang ◽

Yan Shen ◽

...

Keyword(s):

Computed Tomography ◽

Case Report ◽

Young Woman ◽

Benign Tumor ◽

Abdominal Distension ◽

Accurate Diagnosis ◽

Cystic Tumor ◽

Rare Benign Tumor ◽

Radical Surgical Resection

Background: Hemolymphangioma is a rare benign tumor. To the best of our knowledge, there were only 10 reports of this tumor of the pancreas until March 2018. Case Report: Here, we reported a large invasive hemolymphangioma of the pancreas in a young woman with a complaint of abdominal distension and an epigastric mass about 3 weeks. She was found to have a huge multilocular cystic tumor at the neck and body of pancreas on computed tomography. She was eventually diagnosed with hemolymphangioma of the pancreas after operation. After 2 years of follow-up, there was no signs of recurrence. Conclusion: From our case and literature, we can conclude that hemolymphangioma of the pancreas is uncommon benign tumor, and it is hard to make an accurate diagnosis preoperatively. Radical surgical resection should be performed whenever possible. The prognosis of this disease seems good.

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Testicular fibroma: A case report

Archive of oncology ◽

10.2298/aoo1304139s ◽

2013 ◽

Vol 21 (3-4) ◽

pp. 139-140

Author(s):

Sunita Shere ◽

Anjali Kulkarni ◽

Shubhjyoti Pore ◽

Rajan Bindu

Keyword(s):

Case Report ◽

Benign Tumor ◽

Histopathological Diagnosis ◽

Testicular Mass ◽

Rare Benign Tumor ◽

Testicular Malignancy ◽

Slow Growing

Testicular fibroma of gonadal stromal origin is a rare benign tumor of testis, which usually presents as a slow growing testicular mass. Intratesticular fibroma of gonadal stromal origin, with or without minor sex cord elements, must be considered, analogous to similar tumors in ovary, as a benign tumor. Until now, only 25 cases of testicular fibroma have been reported in the literature. We reported a case of testicular fibroma in a 20 years male who presented with painless right testicular enlargement since two years. Ultrasonography (USG) showed heterogeneous mass in right scrotum suggestive of testicular malignancy. Right orchidectomy was done. Histopathological diagnosis was testicular fibroma, which was confirmed by immunohistochemistry.

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