Three-dimensional printing technology for localised thoracoscopic segmental resection for lung cancer

Abstract Background Three-dimensional (3D) CT reconstruction technology has gained increasing attention owing to its potential in locating ground glass nodules in the lung. The 3D printing technology additionally allows visualising the surrounding anatomical structure and variations. However, the clinical utility of these techniques is not known. We aimed to establish a lung tumour and an anatomical lung model using three-dimensional (3D) printing and 3D chest computed tomography (CT) reconstruction and to evaluate the clinical potential of 3D printing technology in uniportal video-assisted thoracoscopic segmentectomy. Methods Eighty-nine patients with ground glass nodules who underwent uniportal video-assisted thoracoscopic segmentectomy were divided into the following groups: Group A, lung models for pre-positioning and simulated surgery that were made with 3D chest CT reconstruction and 3D printing; Group B, patients who underwent chest CT scans with image enhancement for 3D reconstruction. The differences in the surgery approach transfer rate, surgical method conversion rate, operative time, intraoperative blood loss, and postoperative complication rate were compared between the groups. Results The surgery approach transfer rate was 0% and 10.5% for Groups A and B, respectively, showing a significant difference (p = 0.030). The operative time was 2.07 ± 0.24 hours and 2.55 ± 0.41 hours, respectively, showing a significant difference (p<༜0.001). Intraoperative blood loss volume was 43.25 ± 13.63 and 96.68 ± 32.82 ml, respectively, showing a significant difference (p<༜0.001). The postoperative complication rate was 3.9% and 13.2%, respectively, showing a non-significant difference (P = 0.132). The rate of surgical method conversion to lobectomy in Group A was 0%, which was significantly lower than that of 10.5% in group B (p < 0.030). Conclusions 3D printing technology helps surgeons to locate the nodules more accurately, as it is based on 2D and 3D imaging findings, thereby improving the accuracy and safety of surgery. This technique is worth for application in clinical practice. Trial registration: Retrospectively registered.

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Three-dimensional printing technology for localised thoracoscopic segmental resection for lung cancer : a quasi-randomised clinical trial

10.21203/rs.3.rs-19927/v2 ◽

2020 ◽

Author(s):

Yangming Chen ◽

Jiguang Zhang ◽

Qianshun Chen ◽

Tian Li ◽

Kai Chen ◽

...

Keyword(s):

3D Printing ◽

Three Dimensional ◽

Chest Ct ◽

Ct Reconstruction ◽

Printing Technology ◽

3D Printing Technology ◽

Significant Difference ◽

Group A ◽

Group B ◽

Ground Glass Nodules

Abstract Background : Three-dimensional (3D) computed tomography (CT) reconstruction technology has gained increasing attention owing to its potential in locating ground glass nodules in the lung. The 3D printing technology additionally allows the visualisation of the surrounding anatomical structure and variations. However, the clinical utility of these techniques is unknown. This study aimed to establish a lung tumour and an ana tomical lung model using 3D printing and 3D chest CT reconstruction and to evaluate the clinical potential of 3D printing technology in uniportal video-assisted thoracoscopic segmentectomy . Methods : Eighty-nine patients with ground glass nodules who underwent uniportal video-assisted thoracoscopic segmentectomy were classified into the following groups: Group A, lung models for pre-positioning and simulated surgery that were made with 3D chest CT reconstruction and 3D printing; Group B, patients who underwent chest CT scans with image enhancement for 3D reconstruction. The differences in the surgery approach transfer rate, surgical method conversion rate, operative time, intraoperative blood loss, and postoperative complication rate were compared between the groups. Results : The surgery approach transfer rate was 0% and 10.5% for Groups A and B, respectively, showing a significant difference (p=0.030); the operative time was 2.07±0.24 hours and 2.55±0.41 hours, respectively, indicating a significant difference (p<＜0.001); intraoperative blood loss volume was 43.25±13.63 and 96.68±32.82 mL, respectively, demonstrating a significant difference (p<＜0.001); the postoperative complication rate was 3.9% and 13.2%, respectively, showing a non-significant difference (P=0.132). The rate of surgical method conversion to lobectomy in Group A was 0%, which was significantly lower than that of 10.5% in group B (p<0.030). Conclusions : 3D printing technology facilitates a more accurate location of nodules by surgeons, as it is based on two-dimensional and 3D imaging findings, thereby improving the accuracy and safety of surgery. This technique is worth applying in clinical practice.

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Traditional versus mirror three-dimensional printing technology for isolated acetabular fractures: a retrospective study with a median follow-up of 25 months

Journal of International Medical Research ◽

10.1177/03000605211028554 ◽

2021 ◽

Vol 49 (6) ◽

pp. 030006052110285

Author(s):

Kai Xiao ◽

Bo Xu ◽

Lin Ding ◽

Weiguang Yu ◽

Lei Bao ◽

...

Keyword(s):

3D Printing ◽

Three Dimensional ◽

Operation Time ◽

Harris Hip Score ◽

Acetabular Fractures ◽

Printing Technology ◽

Three Dimensional Printing ◽

3D Printing Technology ◽

Significant Difference

Objective To assess the outcomes of traditional three-dimensional (3D) printing technology (TPT) versus mirror 3D printing technology (MTT) in treating isolated acetabular fractures (IAFs). Methods Consecutive patients with an IAF treated by either TPT or MTT at our tertiary medical centre from 2012 to 2018 were retrospectively reviewed. Follow-up was performed 1, 3, 6, and 12 months postoperatively and annually thereafter. The primary outcome was the Harris hip score (HHS), and the secondary outcomes were major intraoperative variables and key orthopaedic complications. Results One hundred fourteen eligible patients (114 hips) with an IAF (TPT, n = 56; MTT, n = 58) were evaluated. The median follow-up was 25 months (range, 21–28 months). At the last follow-up, the mean HHS was 82.46 ±14.70 for TPT and 86.30 ± 13.26 for MTT with a statistically significant difference. Significant differences were also detected in the major intraoperative variables (operation time, intraoperative blood loss, number of fluoroscopic screenings, and anatomical reduction number) and the major orthopaedic complications (loosening, implant failure, and heterotopic ossification). Conclusion Compared with TPT, MTT tends to produce accurate IAF reduction and may result in better intraoperative variables and a lower rate of major orthopaedic complications.

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Comparing the Effectiveness of 3D Printing Technology in the Treatment of Clavicular Fracture between Surgeons with Different Experiences

10.21203/rs.3.rs-940167/v1 ◽

2021 ◽

Author(s):

Jiang long Guo ◽

Hong yi Li ◽

Kui Zhao ◽

Meng Zhang ◽

Jing zhi Ye ◽

...

Keyword(s):

3D Printing ◽

Standard Dose ◽

Operation Time ◽

3D Models ◽

P Value ◽

Printing Technology ◽

3D Printing Technology ◽

Value Range ◽

Group A ◽

Group B

Abstract Purpose To comparethe effectiveness of the three-dimensional (3D) printing technology in the treatment of clavicularfracturebetween experienced and inexperienced orthopedic surgeons. Methods A total of 80 patients with clavicle fracture (from February 2017 to May 2021)were enrolled in our study. Patients were divided randomly into four groups: group A: Patients underwent low-dose CT scan and 3D models were printed before surgeries performed by inexperienced surgeons; group B: Standard-dose CT were taken and 3D models were printed before surgeries performed by experienced surgeons; group C and D: Standard-dose CT were taken in both groups, and the operations were performed differently by inexperienced (group C) and experienced (group D) surgeons. Operation time, blood loss, length of incision and number of intraoperative fluoroscopy were recorded. Results No statistically significant differences were found in age, gender, fracture site and fracture type (P value: 0.23–0.88).Group A showed shorter incision length and less intraoperative fluoroscopy times than group C and D (P value < 0.05). There were no significant differences in blood loss volume, incision length and number of intraoperative time between group A and group B (P value range: 0.11–0.28). The operation time of group A was no longer than that of group C and D (P value range: 0.11 and 0.24). Conclusion The surgical effectiveness of inexperienced surgeons who applied 3D printing technology before clavicular fracture operation were better than those of both inexperienced and experienced surgeons did not use preoperative 3D printing technology.

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The effect of three-dimensional (3D) printing on quantitative and qualitative outcomes in paediatric orthopaedic osteotomies: a systematic review

EFORT Open Reviews ◽

10.1302/2058-5241.6.200092 ◽

2021 ◽

Vol 6 (2) ◽

pp. 130-138

Author(s):

Mohsen Raza ◽

Daniel Murphy ◽

Yael Gelfer

Keyword(s):

Systematic Review ◽

3D Printing ◽

Blood Loss ◽

Operating Time ◽

Three Dimensional ◽

Patient Specific ◽

Printing Technology ◽

3D Printing Technology ◽

Significant Difference ◽

Paediatric Orthopaedic

Three-dimensional (3D) printing technology is increasingly being utilized in various surgical specialities. In paediatric orthopaedics it has been applied in the pre-operative and intra-operative stages, allowing complex deformities to be replicated and patient-specific instrumentation to be used. This systematic review analyses the literature on the effect of 3D printing on paediatric orthopaedic osteotomy outcomes. A systematic review of several databases was conducted according to PRISMA guidelines. Studies evaluating the use of 3D printing technology in orthopaedic osteotomy procedures in children (aged ≤ 16 years) were included. Spinal and bone tumour surgery were excluded. Data extracted included demographics, disease pathology, target bone, type of technology, imaging modality used, qualitative/quantitative outcomes and follow-up. Articles were further categorized as either ‘pre-operative’ or ‘intra-operative’ applications of the technology. Twenty-two articles fitting the inclusion criteria were included. The reported studies included 212 patients. There were five articles of level of evidence 3 and 17 level 4. A large variety of outcomes were reported with the most commonly used being operating time, fluoroscopic exposure and intra-operative blood loss. A significant difference in operative time, fluoroscopic exposure, blood loss and angular correction was found in the ‘intra-operative’ application group. No significant difference was found in the ‘pre-operative’ category. Despite a relatively low evidence base pool of studies, our aggregate data demonstrate a benefit of 3D printing technology in various deformity correction applications, especially when used in the ‘intra-operative’ setting. Further research including paediatric-specific core outcomes is required to determine the potential benefit of this novel addition. Cite this article: EFORT Open Rev 2021;6:130-138. DOI: 10.1302/2058-5241.6.200092

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Porous PLAs with Controllable Density by FDM 3D Printing and Chemical Foaming Agent

Micromachines ◽

10.3390/mi12080866 ◽

2021 ◽

Vol 12 (8) ◽

pp. 866

Author(s):

A. R. Damanpack ◽

André Sousa ◽

M. Bodaghi

Keyword(s):

3D Printing ◽

Flow Rate ◽

Three Dimensional ◽

Poly Lactic Acid ◽

Layer By Layer ◽

Printing Technology ◽

Material Density ◽

Foaming Agent ◽

3D Printing Technology ◽

Fabrication Parameters

This paper shows how fused decomposition modeling (FDM), as a three-dimensional (3D) printing technology, can engineer lightweight porous foams with controllable density. The tactic is based on the 3D printing of Poly Lactic Acid filaments with a chemical blowing agent, as well as experiments to explore how FDM parameters can control material density. Foam porosity is investigated in terms of fabrication parameters such as printing temperature and flow rate, which affect the size of bubbles produced during the layer-by-layer fabrication process. It is experimentally shown that printing temperature and flow rate have significant effects on the bubbles’ size, micro-scale material connections, stiffness and strength. An analytical equation is introduced to accurately simulate the experimental results on flow rate, density, and mechanical properties in terms of printing temperature. Due to the absence of a similar concept, mathematical model and results in the specialized literature, this paper is likely to advance the state-of-the-art lightweight foams with controllable porosity and density fabricated by FDM 3D printing technology.

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Three-Dimensional Technology Applications in Maxillofacial Reconstructive Surgery: Current Surgical Implications

Nanomaterials ◽

10.3390/nano10122523 ◽

2020 ◽

Vol 10 (12) ◽

pp. 2523

Author(s):

Yasmin Ghantous ◽

Aysar Nashef ◽

Aladdin Mohanna ◽

Imad Abu-El-naaj

Keyword(s):

3D Printing ◽

Head And Neck ◽

Donor Site ◽

Maxillofacial Surgery ◽

Three Dimensional ◽

Oral And Maxillofacial Surgery ◽

3D Technology ◽

Printing Technology ◽

Reconstructive Procedures ◽

3D Printing Technology

Defects in the oral and maxillofacial (OMF) complex may lead to functional and esthetic impairment, aspiration, speech difficulty, and reduced quality of life. Reconstruction of such defects is considered one of the most challenging procedures in head and neck surgery. Transfer of different auto-grafts is still considered as the “gold standard” of regenerative and reconstructive procedures for OMF defects. However, harvesting of these grafts can lead to many complications including donor-site morbidity, extending of surgical time, incomplete healing of the donor site and others. Three-dimensional (3D) printing technology is an innovative technique that allows the fabrication of personalized implants and scaffolds that fit the precise anatomy of an individual’s defect and, therefore, has attracted significant attention during the last few decades, especially among head and neck surgeons. Here we discuss the most relevant applications of the 3D printing technology in the oral and maxillofacial surgery field. We further show different clinical examples of patients who were treated at our institute using the 3D technology and discuss the indications, different technologies, complications, and their clinical outcomes. We demonstrate that 3D technology may provide a powerful tool used for reconstruction of various OMF defects, enabling optimal clinical results in the suitable cases.

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Comparison of Presurgical Dental Models Manufactured with Two Different Three-Dimensional Printing Techniques

Journal of Healthcare Engineering ◽

10.1155/2020/8893338 ◽

2020 ◽

Vol 2020 ◽

pp. 1-6 ◽

Cited By ~ 1

Author(s):

Marcin Metlerski ◽

Katarzyna Grocholewicz ◽

Aleksandra Jaroń ◽

Mariusz Lipski ◽

Grzegorz Trybek ◽

...

Keyword(s):

3D Printing ◽

Oral Surgery ◽

Three Dimensional ◽

Mean Deviation ◽

Printing Technology ◽

Three Dimensional Printing ◽

Reference Models ◽

3D Printing Technology ◽

Dimensional Printing ◽

Printing Time

Three-dimensional printing is a rapidly developing area of technology and manufacturing in the field of oral surgery. The aim of this study was comparison of presurgical models made by two different types of three-dimensional (3D) printing technology. Digital reference models were printed 10 times using fused deposition modelling (FDM) and digital light processing (DLP) techniques. All 3D printed models were scanned using a technical scanner. The trueness, linear measurements, and printing time were evaluated. The diagnostic models were compared with the reference models using linear and mean deviation for trueness measurements with computer software. Paired t-tests were performed to compare the two types of 3D printing technology. A P value < 0.05 was considered statistically significant. For FDM printing, all average distances between the reference points were smaller than the corresponding distances measured on the reference model. For the DLP models, the average distances in the three measurements were smaller than the original. Only one average distance measurement was greater. The mean deviation for trueness was 0.1775 mm for the FDM group and 0.0861 mm for the DLP group. Mean printing time for a single model was 517.6 minutes in FDM technology and 285.3 minutes in DLP. This study confirms that presurgical models manufactured with FDM and DLP technologies are usable in oral surgery. Our findings will facilitate clinical decision-making regarding the best 3D printing technology to use when planning a surgical procedure.

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Three-Dimensional Printing: Custom-Made Implants for Craniomaxillofacial Reconstructive Surgery

Craniomaxillofacial Trauma & Reconstruction ◽

10.1055/s-0036-1594277 ◽

2017 ◽

Vol 10 (2) ◽

pp. 089-098 ◽

Cited By ~ 3

Author(s):

Mariana Matias ◽

Horácio Zenha ◽

Horácio Costa

Keyword(s):

3D Printing ◽

Reconstructive Surgery ◽

Three Dimensional ◽

Tactile Feedback ◽

Current Status ◽

Printing Technology ◽

Three Dimensional Printing ◽

3D Printing Technology ◽

Custom Made ◽

The Aesthetic

Craniomaxillofacial reconstructive surgery is a challenging field. First it aims to restore primary functions and second to preserve craniofacial anatomical features like symmetry and harmony. Three-dimensional (3D) printed biomodels have been widely adopted in medical fields by providing tactile feedback and a superior appreciation of visuospatial relationship between anatomical structures. Craniomaxillofacial reconstructive surgery was one of the first areas to implement 3D printing technology in their practice. Biomodeling has been used in craniofacial reconstruction of traumatic injuries, congenital disorders, tumor removal, iatrogenic injuries (e.g., decompressive craniectomies), orthognathic surgery, and implantology. 3D printing has proven to improve and enable an optimization of preoperative planning, develop intraoperative guidance tools, reduce operative time, and significantly improve the biofunctional and the aesthetic outcome. This technology has also shown great potential in enriching the teaching of medical students and surgical residents. The aim of this review is to present the current status of 3D printing technology and its practical and innovative applications, specifically in craniomaxillofacial reconstructive surgery, illustrated with two clinical cases where the 3D printing technology was successfully used.

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3D PRINTING TECHNOLOGY IN HUMAN ANATOMY MODERN TEACHING AND LEARNING

SOCIETY INTEGRATION EDUCATION Proceedings of the International Scientific Conference ◽

10.17770/sie2019vol1.3713 ◽

2019 ◽

Vol 1 ◽

pp. 234

Author(s):

Dzintra Kazoka ◽

Mara Pilmane

Keyword(s):

3D Printing ◽

Teaching And Learning ◽

Three Dimensional ◽

Human Anatomy ◽

Anatomical Models ◽

Printing Technology ◽

3D Printing Technology ◽

Medical Study ◽

Study Process ◽

Teaching Learning

There are various combinations of 3D printing technology and medical study process. The aim of this study was to summarize our first experience on 3D printing and outline how 3D printed models can be successfully used in Human Anatomy modern teaching and learning. In 2018 autumn semester, together with traditional methods, a three-dimensional (3D) printing has been introduced into Human Anatomy curriculum at Department of Morphology. In practical classes 39 groups of students from Faculty of Medicine 1st year together with 3 tutors used 3 different open source softwares to create anatomical models and prepared them for printing process. All anatomical models were produced using an FDM 3D printer, a Prusa i3 MK2 (Prusa Research). As methods for data collection were used our observational notes during teaching and learning, analysis of discussions between tutors and students, comments on the preparing and usability of the created and printed models. 3D printing technology offered students a powerful tool for their teaching, learning and creativity, provided possibility to show human body structures or variations. Presented data offered valuable information about current situation and these results were suitable for the further development of the Human Anatomy study course.

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