Relationship Between Oxygen Radical Absorbance Capacity (ORAC) Index, Body Composition and Blood Biochemical Markers in Overweight /Obese Compared to Normal Weight Subjects

Abstract Background: Obesity is an important preventable disease, which promotes the development of chronic disorders by altering several factors including oxidative stress. Dietary antioxidants protect the body against oxidative stress. The purpose of this study was to evaluate the potential association of oxygen radical absorbance capacity (ORAC) index with obesity and its associated features in adults.Methods: participants were divided in two groups of normal weight and overweight /obesity. General characteristics were registered and a 147-item food frequency questionnaire was completed. Thereafter, anthropometric measurements were conducted. Biochemical indices were obtained from science and Research branch of Islamic Azad University of Tehran, Iran. The amount of the dietary ORAC index was estimated using the data provided by the USDA Foods Table.Results: The results showed that there was a significant difference between the normal and overweight/obese groups in terms of body mass index (BMI) and waist-to-hip ratio (WHR) (P=0.0001). Participants with normal weight consumed more fruits and vegetables than another group. Also, the dietary ORAC index in normal individuals was higher than the case group, but there was not significant difference (P=0.352). There was also a significant inverse correlation between dietary ORAC and BMI and WHR, whereas a significant positive correlation between dietary ORAC and plasma HDL was observed (P<0.05).Conclusion: Our findings suggest that dietary antioxidants is inversely associated with BMI, fasting blood glucose, triglyceride, total Cholesterol and LDL in both groups. It seems that following a diet rich in antioxidants can counteract obesity and its associated comorbidities.

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Relationship Between Oxygen Radical Absorbance Capacity (ORAC) Index, Body Composition and Blood Biochemical Markers in Overweight /Obese Compared to Normal Weight Subjects: A Cross-Sectional Study

10.21203/rs.3.rs-109641/v1 ◽

2020 ◽

Author(s):

Zahra Madani ◽

Maryam Moussavi Javardi ◽

Ghazaleh Khalili ◽

Sayed Abolghassem Djazayeri ◽

Ariyo Movahedi ◽

...

Keyword(s):

Oxidative Stress ◽

Fasting Blood Glucose ◽

Oxygen Radical ◽

Normal Weight ◽

The Body ◽

Oxygen Radical Absorbance Capacity ◽

Case Group ◽

Dietary Antioxidants ◽

Cross Sectional ◽

Significant Difference

Abstract Background: Obesity is an important preventable disease, which promotes the development of chronic disorders by altering several factors including oxidative stress. Dietary antioxidants protect the body against oxidative stress. The purpose of this study was to evaluate the potential association of oxygen radical absorbance capacity (ORAC) index with obesity and its associated features in adults.Methods: participants were divided in two groups of normal weight and overweight /obesity. General characteristics were registered and a 147-item food frequency questionnaire was completed. Thereafter, anthropometric measurements were conducted. Biochemical indices were obtained from science and Research branch of Islamic Azad University of Tehran, Iran. The amount of the dietary ORAC index was estimated using the data provided by the USDA Foods Table.Results: The results showed that there was a significant difference between the normal and overweight/obese groups in terms of body mass index (BMI) and waist-to-hip ratio (WHR) (P=0.0001). Participants with normal weight consumed more fruits and vegetables than another group. Also, the dietary ORAC index in normal individuals was higher than the case group, but there was not significant difference (P=0.352). There was also a significant inverse correlation between dietary ORAC and BMI and WHR, whereas a significant positive correlation between dietary ORAC and plasma HDL was observed (P<0.05).Conclusion: Our findings suggest that dietary antioxidants is inversely associated with BMI, fasting blood glucose, triglyceride, total Cholesterol and LDL in both groups. It seems that following a diet rich in antioxidants can counteract obesity and its associated comorbidities.

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Relationship between oxygen radical absorbance capacity (ORAC) index, body composition and blood biochemical markers in overweight /obese compared to normal weight subjects: a cross-sectional study

10.21203/rs.3.rs-31628/v2 ◽

2020 ◽

Author(s):

Zahra Madani ◽

Maryam sadat Mousavi javardi ◽

Seyyed abolghassem Djazayeri ◽

Ariyo Movahedi ◽

Majid Karandish

Keyword(s):

Oxidative Stress ◽

Fasting Blood Glucose ◽

Oxygen Radical ◽

Normal Weight ◽

The Body ◽

Oxygen Radical Absorbance Capacity ◽

Case Group ◽

Dietary Antioxidants ◽

Cross Sectional ◽

Significant Difference

Abstract Background: Obesity is an important preventable disease, which promotes the development of chronic disorders by altering several factors including oxidative stress. Dietary antioxidants protect the body against oxidative stress. The purpose of this study was to evaluate the potential association of oxygen radical absorbance capacity (ORAC) index with obesity and its associated features in adults.Methods: participants were divided in two groups of normal weight and overweight /obesity. General characteristics were registered and a 147-item food frequency questionnaire was completed. Thereafter, anthropometric measurements were conducted. Biochemical indices were obtained from science and Research branch of Islamic Azad University of Tehran, Iran. The amount of the dietary ORAC index was estimated using the data provided by the USDA Foods Table.Results: The results showed that there was a significant difference between the normal and overweight/obese groups in terms of body mass index (BMI) and waist-to-hip ratio (WHR) (P=0.0001). Participants with normal weight consumed more fruits and vegetables than another group. Also, the dietary ORAC index in normal individuals was higher than the case group, but there was not significant difference (P=0.352). There was also a significant inverse correlation between dietary ORAC and BMI and WHR, whereas a significant positive correlation between dietary ORAC and plasma HDL was observed (P<0.05).Conclusion: Our findings suggest that dietary antioxidants is inversely associated with BMI, fasting blood glucose, triglyceride, total Cholesterol and LDL in both groups. It seems that following a diet rich in antioxidants can counteract obesity and its associated comorbidities.

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Relationship between oxygen radical absorbance capacity (ORAC) index, body composition and blood biochemical markers in overweight /obese compared to normal weight subjects: a cross-sectional study

10.21203/rs.3.rs-31628/v1 ◽

2020 ◽

Author(s):

Zahra Madani ◽

Maryam sadat Mousavi javardi ◽

Seyyed abolghassem Djazayeri ◽

Ariyo Movahedi ◽

Majid Karandish

Keyword(s):

Oxidative Stress ◽

Fasting Blood Glucose ◽

Oxygen Radical ◽

Normal Weight ◽

The Body ◽

Oxygen Radical Absorbance Capacity ◽

Case Group ◽

Dietary Antioxidants ◽

Cross Sectional ◽

Significant Difference

Abstract Backgroumd: Obesity is an important preventable disease, which promotes the development of chronic disorders by altering several factors including oxidative stress. Dietary antioxidants protect the body against oxidative stress. The purpose of this study was to evaluate the potential association of oxygen radical absorbance capacity (ORAC) index with obesity and its associated features in adults.Methods: participants were divided in two groups of normal weight and overweight /obesity. General characteristics were registered and a 147-item food frequency questionnaire was completed. Thereafter, anthropometric measurements were conducted. Biochemical indices were obtained from science and Research branch of Islamic Azad University of Tehran, Iran. The amount of the dietary ORAC index was estimated using the data provided by the USDA Foods Table.Results: The results showed that there was a significant difference between the normal and overweight/obese groups in terms of body mass index (BMI) and waist-to-hip ratio (WHR) (P=0.0001). Participants with normal weight consumed more fruits and vegetables than another group. Also, the dietary ORAC index in normal individuals was higher than the case group, but there was not significant difference (P=0.352). There was also a significant inverse correlation between dietary ORAC and BMI and WHR, whereas a significant positive correlation between dietary ORAC and plasma HDL was observed (P<0.05).Conclusion: Our findings suggest that dietary antioxidants is inversely associated with BMI, fasting blood glucose, triglyceride, total Cholesterol and LDL in both groups. It seems that following a diet rich in antioxidants can counteract obesity and its associated comorbidities.

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Association of Anthropometric Measurements With Oxidant-Antioxidant Status Among Young Saudi Females

Physiological Research ◽

10.33549/physiolres.933785 ◽

2018 ◽

pp. 787-793

Author(s):

R. LATIF ◽

N. RAFIQUE

Keyword(s):

Oxidative Stress ◽

Dna Damage ◽

Body Fat ◽

Positive Association ◽

Normal Weight ◽

The Body ◽

Anthropometric Measurements ◽

Oxidative Stress Biomarkers ◽

Obese Adolescent ◽

Stress Biomarkers

Present study aimed to explore the levels and correlation of oxidative stress biomarkers with anthropometry in a population of young Saudi females. One hundred six normotensives, non-diabetic Saudi females, with minimally active lifestyle, based on their body mass index (BMI) were divided as; normal-weight (NW; n=52), overweight (OW; n=24) and obese (OB; n=30). Anthropometric measurements [BMI, Waist Circumference (WC), Waist-Hip Ratio (WHR), Body Density (BD), Body Adiposity Index (BAI), % Body fat] and oxidative stress biomarkers; Thiobarbituric acid reactive substances (TBARS), 8-hydroxy-2-deoxyguanosine (8-OH-2dG: indicative of DNA/RNA damage), Superoxide dismutase, Serum total antioxidant capacity) were recorded. There was statistically significant higher 8-OH-2dG (pg/ml) in OB compared to NW (800.63±6.19 vs. 780.22±3.34; p=0.007), as determined by one-way ANOVA and Tukey post hoc test. 8-OH-2dG was significantly and positively associated with BMI (r=0.286, p=0.004), WC (r=0.280, p=0.005), BAI (r=0.26, p=0.008), and % body fat (r=0.27, p=0.006). There may be significantly increased DNA damage in normoglycemic, normotensive obese adolescent females. This can be linked to the amount of adipose tissue in the body as depicted by strong positive association between DNA damage and BMI, WC, BAI, and % body fat.

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Hypoglycemic and antioxidative activities of ethanol seed extract of Hunteria umbellate (Hallier F.) on streptozotocin-induced diabetic rats

Clinical Phytoscience ◽

10.1186/s40816-021-00285-1 ◽

2021 ◽

Vol 7 (1) ◽

Author(s):

Olubanke O. Ogunlana ◽

Babatunde O. Adetuyi ◽

Miracle Rotimi ◽

lohor Esalomi ◽

Alaba Adeyemi ◽

...

Keyword(s):

Oxidative Stress ◽

Blood Glucose ◽

Blood Glucose Level ◽

Glucose Level ◽

Fasting Blood Glucose ◽

Diabetic Rats ◽

Seed Extract ◽

The Body ◽

High Concentration ◽

Group 5

Abstract Background Diabetes, a global cause of mortality in developing countries is a chronic disorder affecting the metabolism of macromolecules and has been attributed to the defective production and action of insulin characterized by persistent hyperglycemic properties. This global disorder harms organs of the body such as the liver, kidney and spleen. Medicinal plants such as Hunteria umbellate have been shown to possess hypoglycemic, antioxidative and anti-diabetic properties owing to the high concentration of active phytochemical constituents like flavonoids and alkaloids. The present study seeks to evaluate the hypoglycemic activities of ethanolic seed extract of Hunteria umbellate on streptozotocin-induced diabetes rats. Methods Thirty (30) female experimental rats were randomly divided into five groups with six rats per group and were administered streptozotocin (STZ) and Hunteria umbellate as follows. Group 1 served as control and was given only distilled water, group 2 rats were administered 60 mg/kg STZ; Group 3 was administered 60 mg/kg STZ and 100 mg/kg metformin; group 4 rats were administered 60 mg/kg STZ and 800 mg/kg Hunteria umbellate, group 5 rats 60 mg/kg STZ and 400 mg/kg Hunteria umbellate. The fasting blood glucose level of each rat was measured before sacrifice. Rats were then sacrificed 24 h after the last dose of treatment. Results The results showed that Hunteria umbellate significantly reversed STZ-induced increase in fasting blood glucose and increase in body and organs weight of rats. Hunteria umbellate significantly reversed STZ-induced decrease in antioxidant enzyme in liver, kidney and spleen of rats. Hunteria umbellate significantly reversed STZ-induced increase in oxidative stress markers in liver, kidney and spleen of rats. Conclusion Collectively, our results provide convincing information that inhibition of oxidative stress and regulation of blood glucose level are major mechanisms through which Hunteria umbellate protects against streptozotocin-induced diabketes rats.

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Perbedaan Kadar Glutation (GSH) Hepar Tikus Putih Jantan (Rattus norvegicus) yang diinduksi Parasetamol Dosis Toksik dengan Pemberian Ekstrak Daun Kelor (Moringa oleifera)

Jurnal Ilmiah Universitas Batanghari Jambi ◽

10.33087/jiubj.v20i1.881 ◽

2020 ◽

Vol 20 (1) ◽

pp. 247

Author(s):

Nur Insani ◽

H.M.T Kamaluddin ◽

Swanny Swanny

Keyword(s):

Oxidative Stress ◽

Treatment Group ◽

Leaf Extract ◽

The Body ◽

Control Group ◽

Bb Rat ◽

Toxic Dose ◽

Experimental Animals ◽

Significant Difference ◽

Group Ii

Glutathione (GSH) transferase deficiency due to paracetamol exposure causes further oxidative stress to liver necrosis. To reduce oxidative stress that can cause damage to the liver of the body requires antioxidants. One plant to treat liver disease is the kelor leaf (because it has an active flavonoid material also has antioxidant activity). This study was conducted to determine the difference of glutathione hepar levels of male white rat induced paracetamol toxic dose by giving kelor leaf extract. The type of research is experimental laboratory in vivo with rancagan randomized post test only control group design. With the stages as follows 1.Leaf Extract Kelor with Ethanol 96%, 2.Perpeteration of experimental animals, 3.Treatment of experimental animals by giving extract of 3-dose of kelor leaf that is KP I 250 mg / 200 gr BB rat, KP II 500 mg / 200 gr BB rat, KP III 1000 mg / 200 gr BB rat for 14 days combined with paracetamol dose 2 gr / 200 gr BB rat compared with the negative control group (group given only paracetamol dose 2 gr / 200 gr BB rat) and control group positif only fed regular feed for 14 days). The result showed that there was a significant difference mean of GSH levels between all treatment groups obtained p = 0,000 (p <α) p values smaller than 0.05. There was the highest increase of GSH in treatment group II (142,7525 μmol / mg) and lowest dose of GSH in positive control group (57,1812 μmol / mg), dose paracetamol toxic dosage and kelor leaf extract 500 mg / gr BB rat can increase GSH hepar p = 0,000 (p <α) p less than 0 , 05. The conclusion of the test results showed that giving of kelor leaf extract at dose of treatment group II can increase GSH hepar level significantly

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The Effect of Exercise on the Total Leukocyte, Absolute Neutrophil, Lymphocyte and Platelet Counts among Sudanese Football Players

Journal of Drug Delivery and Therapeutics ◽

10.22270/jddt.v11i6-s.5109 ◽

2021 ◽

Vol 11 (6-S) ◽

pp. 26-32

Author(s):

Nihad Elsadig Babiker ◽

Raheeg Mubark Anwer

Keyword(s):

Physiological Stress ◽

Hematological Parameters ◽

Venous Blood ◽

Age Groups ◽

The Body ◽

Case Group ◽

Football Players ◽

Platelet Counts ◽

Significant Difference ◽

Age Variation

Background: Aerobic exercise induces physiological stress on the body and brings changes in hematological parameters. This study aimed to determine the effect of playing football as an exercise on the total white blood cell count, absolute Neutrophil, lymphocyte and Platelet counts among Sudanese football players. Material and method: This was a descriptive case control study, done on a number of football players in Khartoum state, Sudan and conducted within the period from August 2021 to October 2021. Three ml of venous blood samples had been collected from every participant in the study, parameters had been measured and calculated using blood cells counter (Sysmex KX-21N). Results: When compared the TWBCs, Absolute Neutrophil, Lymphocytes and platelet counts between cases and control there was a significant differences with (P ≤0.05). Also there was a significant difference in the case group before and after one hour of exercise with (P =0.00), and in significant differences between different age groups with (P ≥0.05). Conclusion: Playing football for 1 hour cause a significant increase in the TWBCs, absolute Neutrophils, absolute Lymphocytes and Platelets counts. Age variation has no effect on the measured parameters Keywords: Football, TWBCs, Neutrophils, Lymphocytes and Platelets.

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VALIDITY OF THREE-DIMENSIONAL PHOTONIC SCANNING TECHNIQUE FOR ESTIMATING PERCENT BODY FAT

Journal of Frailty & Aging ◽

10.14283/jfa.2013.28 ◽

2013 ◽

pp. 1-6

Author(s):

K. SHITARA ◽

H. KANEHISA ◽

T. FUKUNAGA ◽

T. YANAI ◽

Y. KAWAKAMI

Keyword(s):

Body Fat ◽

Lung Volume ◽

Three Dimensional ◽

The Body ◽

Percent Body Fat ◽

Body Volume ◽

Mean Values ◽

Significant Difference ◽

Human Body Surface ◽

Estimated Error

Background:Three-dimensional photonic scanning (3DPS) was recently developed to measuredimensions of a human body surface. Objective:The purpose of this study was to explore the validity of bodyvolume measured by 3DPS for estimating the percent body fat (%fat). Design, setting, participants, andmeasurement:The body volumes were determined by 3DPS in 52 women. The body volume was corrected forresidual lung volume. The %fat was estimated from body density and compared with the corresponding referencevalue determined by the dual-energy x-ray absorptiometry (DXA). Results:No significant difference was foundfor the mean values of %fat obtained by 3DPS (22.2 ± 7.6%) and DXA (23.5 ± 4.9%). The root mean squareerror of %fat between 3DPS and reference technique was 6.0%. For each body segment, there was a significantpositive correlation between 3DPS- and DXA-values, although the corresponding value for the head was slightlylarger in 3DPS than in DXA. Residual lung volume was negatively correlated with the estimated error in %fat.Conclusions:The body volume determined with 3DPS is potentially useful for estimating %fat. A possiblestrategy for enhancing the measurement accuracy of %fat might be to refine the protocol for preparing thesubject’s hair prior to scanning and to improve the accuracy in the measurement of residual lung volume.

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Oxidative stress in Vitiligo patients and administration of Munzij and Mushil therapy, a poly herbal Unani formulation – hospital-based study

Journal of Complementary and Integrative Medicine ◽

10.1515/jcim-2015-0111 ◽

2020 ◽

Vol 17 (3) ◽

Author(s):

Towseef Amin Rafeeqi ◽

Farhat Jabeen ◽

M A Waheed ◽

Gulam Mohammed Husain ◽

Alokananda Chakraborthy

Keyword(s):

Oxidative Stress ◽

Healthy Subjects ◽

Skin Disorder ◽

Antioxidant Status ◽

The Body ◽

Oxygen Species ◽

Statistical Significant Difference ◽

Significant Difference ◽

Gpx Activity

AbstractBackgroundVitiligo, a skin disorder is viewed as a multifactorial process with major role of reactive oxygen species in concert to destroy or incapacitate melanocytes. In Unani system of medicine the treatment of Bars (Vitiligo) starts with removal of harmful materials from the body with Munzij and Mushil (MM), a poly herbal Unani formulation.MethodsHerein, oxidative stress related parameters as MDA, SOD, GPx and CAT have been estimated in the 21 clinically diagnosed Vitiligo in-patients and subsequently these parameters were evaluated during and after administration of MM therapy and compared with 21 healthy subjects.ResultsThere was significant difference in the parameters viz., SOD (p<0.001) and CAT (p<0.005) activity at the baseline with no statistical significant difference in MDA and GPx activity among Vitiligo subjects and controls. After MM therapy there was no statistical significant difference among the values of these parameters in Vitiligo subjects.ConclusionsThe results suggest that there is imbalance in the oxidant-antioxidant status of Vitiligo subjects and the MM therapy is not found to significantly change the levels of oxidative stress related parameters.

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