scholarly journals The Horse Gallops But So Does the Zebra! A Case Report: Peripheral Ulcerative Keratitis

2020 ◽  
Author(s):  
sarah belghmaidi ◽  
soumia belgadi ◽  
ibtissam Hajji ◽  
abdeljalil Moutaouakil
Keyword(s):  
Case Report ◽  
Corneal Ulcer ◽  
Tear Film ◽  
Skin Lesions ◽  
Collaborative Management ◽  
Test Results ◽  
Schirmer Test ◽  
Peripheral Ulcerative Keratitis ◽  
Ulcerative Keratitis ◽  
Corneal Thinning

Abstract Introduction: Peripheral ulcerative keratitis (PUK) is an aggressive, potentially sight-threatening cause for peripheral corneal thinningCase report: A 43-year-old woman presented with bilateral tearing and ocular pain persisting for 7 months. Visual acuity was 6/6 in both eyes. On biomicroscopic examination, presence of crescent shaped corneal ulcer with perilesional haziness. A tear film study demonstrated decreased Schirmer test results (5mm in both eyes) and tear film break-up time (5 sec in both eyes). The interrogation and the patient revealed he had recurrent skin lesions in both legs with chronic itching, and recurrent oral and genital ulcers healing spontaneously. The diagnosis of behcet disease was proposed.Conclusion: Collaborative management of ophthalmic patients having systemic illness along with internists improves overall outcomes and prevents morbidity in such patients.

scholarly journals Peripheral Ulcerative Keratitis with Pyoderma Gangrenosum

2015 ◽  
Vol 2015 ◽  
pp. 1-4
Author(s):  
Adrián Imbernón-Moya ◽  
Elena Vargas-Laguna ◽  
Antonio Aguilar ◽  
Miguel Ángel Gallego ◽  
Claudia Vergara ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Pyoderma Gangrenosum ◽  
Early Recognition ◽  
Skin Lesions ◽  
Unusual Event ◽  
Peripheral Ulcerative Keratitis ◽  
Appropriate Treatment ◽  
Autoimmune Conditions ◽  
Ulcerative Keratitis ◽  
Peripheral Cornea

Pyoderma gangrenosum is an unusual necrotizing noninfective and ulcerative skin disease whose cause is unknown. Ophthalmic involvement in pyoderma gangrenosum is an unusual event. Only a few cases have been reported, from which we can highlight scleral, corneal, and orbital cases. Peripheral ulcerative keratitis is a process which destroys the peripheral cornea. Its cause is still unknown although it is often associated with autoimmune conditions. Pyoderma gangrenosum should be included in the differential diagnosis of peripheral ulcerative keratitis. Early recognition of these manifestations can vary the prognosis by applying the appropriate treatment. We introduce a 70-year-old woman who suffered pyoderma gangrenosum associated with peripheral ulcerative keratitis in her left eye. The patient’s skin lesions and peripheral keratitis responded successfully to systemic steroids and cyclosporine A.

scholarly journals DRY EYE STATUS BASED ON THE SCHIRMER TEST AND TEAR FILM BREAK UP TIME RESULTS FOLLOWING USE OF SOFT CONTACT LENS IN KERALA

2019 ◽  
Vol 3 (10) ◽  
Author(s):  
Dr. Simon George
Keyword(s):  
Dry Eye ◽  
Contact Lens ◽  
Tear Film ◽  
Test Results ◽  
Schirmer Test ◽  
Soft Contact ◽  
Soft Contact Lens ◽  
Break Up

Prospective two years study of the dry eye status following use of soft contact lens. Based on the Schirmer test results, 10 % soft contact lens wearers developed mild dry eye at the end of 1 year and 15 % developed mild dry eye at the end of 2 years. No patient had moderate or severe dry eye. Based on the Tear film break up time results, 17 % soft contact lens wearers developed mild dry eye at the end of 1 year and 30 % developed mild dry eye at the end of 2 years. 1% had moderate dry eye at the end of 2 years. No patient had severe dry eye. Keywords: Schirmer test, Tear film break up time, soft contact lens, dry eye

scholarly journals Peripheral Ulcerative Keratitis in a Patient with Bilateral Scleritis: Medical and Surgical Management

2020 ◽  
Vol 11 (3) ◽  
pp. 500-506
Author(s):  
June Artaechevarria Artieda ◽  
Nuria Estébanez-Corrales ◽  
Olga Sánchez-Pernaute ◽  
Nicolás Alejandre-Alba
Keyword(s):  
Oral Prednisone ◽  
Previous History ◽  
Surgical Techniques ◽  
Lamellar Keratoplasty ◽  
Systemic Autoimmune Disease ◽  
Negative Results ◽  
Peripheral Ulcerative Keratitis ◽  
Anterior Lamellar Keratoplasty ◽  
Ulcerative Keratitis ◽  
Corneal Thinning

Peripheral ulcerative keratitis (PUK) is a group of corneal disorders that cause peripheral corneal thinning, threatening globe integrity in advance stages. It is usually associated with systemic autoimmune diseases and management is based on local and systemic approaches. We present the case of a 47-year-old man with a previous history of bacterial keratitis in his left eye presenting with 1 month of bilateral ocular pain and redness. At examination, diffuse bilateral globe inflammation with paracentral corneal thinning in his left eye was observed. He was diagnosed with bilateral scleritis and PUK in his left eye. Workup for associated systemic autoimmune disease yielded negative results. The patient was started on pulses of intravenous methylprednisolone followed by oral prednisone failing to achieve sufficient control of the inflammatory syndrome. Subsequently, periodic intravenous cyclophosphamide was administered with a favorable response. A multilayer amniotic membrane graft was applied, but there was rapid melting with reabsorption of the tissue, resulting in extreme corneal thinning at the inferior paracentral cornea. A decentered 8.5-mm superficial anterior lamellar keratoplasty (SALK) was then performed obtaining the donor graft with a femtosecond laser but performing manual trepanation in the recipient. At 12 months, visual and biomicroscopic measures do not show deterioration and inflammation remains under control with oral azathioprine as maintenance regime. The management of PUK includes both systemic immunosuppression and tectonic procedures to preserve the globe integrity. Diverse surgical techniques have been attempted, but no definitive guidelines are available. Decentered large SALK is a simple technique that can yield acceptable visual results.

Assessment of Tear Film Anomalies in Childhood Obesity

2021 ◽  
Author(s):  
Alper Halil Bayat ◽  
Emre Aydemir ◽  
Gozde Aksoy Aydemir ◽  
Hasim Gencer
Keyword(s):  
Insulin Resistance ◽  
Childhood Obesity ◽  
Ocular Surface ◽  
Tear Film ◽  
Disease Index ◽  
The Body ◽  
Test Results ◽  
Schirmer Test ◽  
Ocular Surface Disease Index ◽  
Breakup Time

Abstract Purpose To determine if childhood obesity has an effect on the ocular surface and tear film of children who are afflicted. Methods Patients who had childhood obesity, 85 eyes, and patients who were healthy, 75 eyes, were enrolled in this prospective and comparative study. The tear film breakup time (TF-BUT), tear meniscus area and height (TMA and TMH) values, Schirmer test scores, and ocular surface disease index (OSDI) scores were obtained for all participants. Results The TMH, TMA, TF-BUT, and Schirmer test results were statistically significantly lower in the obesity group (p < 0.001 for all). The children with obesity and insulin resistance had lower TMH, TMA, TF-BUT, and Schirmer test results when compared to the children without insulin resistance (p < 0.05 for all). The body mass index was found to be correlated with the TMH, TMA, TF-BUT, and Schirmer test results (p < 0.001 for all). Conclusion Children with obesity had lower TMA, TMH, TF-BUT, and Schirmer test results than healthy subjects. When insulin resistance was added to obesity, these values were even lower.

scholarly journals Using Anterior Segment Optical Coherence Tomography to Monitor Disease Progression in Peripheral Ulcerative Keratitis

2018 ◽  
Vol 2018 ◽  
pp. 1-4 ◽  
Author(s):  
Aakriti Garg ◽  
Joaquin De Rojas ◽  
Priya Mathews ◽  
Albert Hazan ◽  
James Lin ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Multidisciplinary Approach ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Optical Coherence ◽  
Careful Monitoring ◽  
Laboratory Findings ◽  
Peripheral Ulcerative Keratitis ◽  
Ulcerative Keratitis ◽  
Corneal Thinning

We report two cases of peripheral ulcerative keratitis (PUK) imaged with anterior segment optical coherence tomography (AS-OCT). The first patient had prolonged nonsteroidal anti-inflammatory drug use, while the second had inflammatory arthritis by laboratory findings without any systemic findings as well as possible concurrent tuberculosis. In both patients, AS-OCT demonstrated corneal thinning at the onset of the disease with improvement six months after initiation of intensive medical therapy. Our cases highlight the need for a multidisciplinary approach and careful monitoring in PUK cases, especially with objective measures such as corneal thickness assessed with AS-OCT.

scholarly journals Difference of Schirmer Test Results Before and After Using Smartphones with Various Screen Brightness Levels

2021 ◽  
Vol 2 (2) ◽  
pp. 1-5
Author(s):  
Dodik Dumadi ◽  
Maharani Maharani ◽  
Tanti Ajoe Kesoema ◽  
Riski Prihatningtias
Keyword(s):  
Tear Film ◽  
Wilcoxon Test ◽  
Test Results ◽  
Research Subjects ◽  
Schirmer Test ◽  
High Brightness ◽  
Significant Difference ◽  
Before And After ◽  
Post Test ◽  
Test Result

Background : The use of smartphones and other digital devices such as laptops and tablets is familiar in Indonesian society. Excessive uses of the devices are associated with dry eye syndrome and tear film dysfunction. The intensity of blue light when penetrating the eye is believed to affect tear film stability. Thus it will encourage tear evaporation which proved by Schirmer test.Objective : To find out the difference of Schirmer test results before and after using a smartphone with  various screen brightness levels.Methods : This study used pretest-posttest quasi-experimental study. The research subjects were students of the Faculty of Medicine, Diponegoro University (n = 30) who were selected by purposive sampling. In this study, the research subjects used smartphones for an hour with a predetermined screen brightness level, with the same room lighting. Before and after treatment the subject was measured the quantity of tears using the Schirmer test. Data were analyzed using the Wilcoxon test, Mann Whitney U test, and Kruskal Wallis test.Results : The average pretest result on low brightness was 25,60 ± 9,44 and the post-test result was 17,60 ± 8,45. The pre-test result on medium brightness was 27,90 ± 9,46 and the post-test result was 24,80 ± 10,46. The pre-test result on high brightness was 23,60 ± 6,80 and the post-test result was 19,10 ± 7,95. The Schirmer test results before and after using smartphones with low brightness showed a significant different (P<0.05) and there was no significant difference for the pre-post test using smartphones with medium and high brightness. Comparison of Schirmer test results on low, medium and high screen brightness did not show a significant difference.Conclusion : There is no significant difference between the Schirmer test results among low, medium and high screen brightness after one hour of smartphone usage.

scholarly journals Peripheral ulcerative keratitis as the first manifestation of Rheumatoid Arthritis – case report

2021 ◽  
Author(s):  
Danielly Dantas Pimentel ◽  
TAISA MORETE DA SILVA ◽  
IANE TAMARA DONDE ◽  
PATRICIA MILANI DE MORAES ◽  
CARLOS AUGUSTO RODRIGUES PADILHA ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Case Report ◽  
Rheumatoid Arthritis Case ◽  
Peripheral Ulcerative Keratitis ◽  
Ulcerative Keratitis

scholarly journals Perforating Peripheral Ulcerative Keratitis in Syphilis

2019 ◽  
Vol 10 (2) ◽  
pp. 267-273
Author(s):  
Pimpiroon Ploysangam ◽  
Ruth Marie Mattern
Keyword(s):  
Case Report ◽  
Sexual Partners ◽  
Corneal Perforation ◽  
Syphilis Infection ◽  
Case Presentation ◽  
Multiple Sexual Partners ◽  
Peripheral Ulcerative Keratitis ◽  
Ulcerative Keratitis

Purpose: To present a case of peripheral ulcerative keratitis with perforation in the setting of syphilis. Method: A single observational case report in urban USA. Case Presentation: A patient with multiple sexual partners presented with bilateral peripheral ulcerative keratitis, unilateral corneal perforation, and a pustular rash. Workup was positive for syphilis as well as HSV, HIV, and multiple autoantibody tests. Findings improved after treatment for syphilis. Conclusion: Bilateral peripheral ulcerative keratitis in syphilis has been reported in one prior case. However, corneal perforation in the setting of syphilis infection has not, to our knowledge, been reported previously.

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