scholarly journals Willingness to use HIV pre-exposure prophylaxis and associated factors among men who have sex with men in Liuzhou, China

2021 ◽  
Author(s):  
Yuansheng Fu ◽  
Akililu Alemu Ashuro ◽  
Xianxiang Feng ◽  
Ting Wang ◽  
Sichen Zhang ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Sexual Behaviors ◽  
Study Participant ◽  
Casual Sex ◽  
Multivariate Logistic Regression ◽  
Factors Associated ◽  
Hiv Test ◽  
Sex With Men ◽  
Willingness To Use ◽  
Exposure Prophylaxis

Abstract Background: HIV pre-exposure prophylaxis (PrEP) is a key component of HIV combination prevention strategies, which has the potential to decrease the incidence of HIV in men who have sex with men (MSM). This study aimed to evaluate the levels of PrEP acceptability and explore the factors associated with willingness to use PrEP among MSM in Liuzhou, China.Methods: Between November 2017 and May 2019, a cross-sectional survey was conducted among 829 MSM. The study participant were recruited through nonprobability sampling method. Participants’ demographics, HIV/AIDS knowledge, sexual behaviors, drug use and HIV test history were collected. Multivariate logistic regression was performed to identify factors associated with willingness to use PrEP.Results: A total of 829 MSM completed the survey, and 30.28%(95%CI: 27.3-33.4) were willing to use PrEP. In multivariate logistic regression, factors associated with a higher willingness to use PrEP include, being Zhuang or Han ethnic origin, recruited through peer introduction or gay venues, pursing higher education level, previous HIV testing and having oral sex with a man. However, had a casual sex in the past six months were associated with lower willingness to use PrEP.Conclusions: MSM in Liuzhou reported a relatively low level of willingness to use PrEP. The results indicate the need for effective education, targeted intervention, and define implementation strategies to promote PrEP acceptance among MSM.

scholarly journals Willingness to use HIV pre-exposure prophylaxis and associated factors among men who have sex with men in Liuzhou, China

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Yuansheng Fu ◽  
Akililu Alemu Ashuro ◽  
Xianxiang Feng ◽  
Ting Wang ◽  
Sichen Zhang ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Sexual Behaviors ◽  
Casual Sex ◽  
Multivariate Logistic Regression ◽  
Cross Sectional Survey ◽  
Factors Associated ◽  
Hiv Test ◽  
Sex With Men ◽  
Willingness To Use ◽  
Exposure Prophylaxis

Abstract Background HIV pre-exposure prophylaxis (PrEP) is a key component of HIV combination prevention strategies and has the potential to decrease the incidence of HIV in men who have sex with men (MSM). This study aimed to evaluate levels of PrEP acceptability and explore factors associated with willingness to use PrEP among MSM in Liuzhou, China. Methods Between November 2017 and May 2019, a cross-sectional survey was conducted among 829 MSM. The study participants were recruited through a nonprobability sampling method. The participants’ demographics, HIV/AIDS knowledge, sexual behaviors, drug use and HIV test history were collected. Multivariate logistic regression was performed to identify factors associated with willingness to use PrEP. Results A total of 829 MSM completed the survey, and 30.28% (95% CI 27.3–33.4) were willing to use PrEP. In multivariate logistic regression, factors associated with a higher willingness to use PrEP included Zhuang or Han ethnic origin, recruitment through peer introduction or gay venues, pursuit of a higher education level, previous HIV testing and oral sex with a man. Conversely, having casual sex in the past 6 months was associated with a lower willingness to use PrEP. Conclusions MSM in Liuzhou reported a relatively low level of willingness to use PrEP. The results indicate the need for effective education, targeted intervention, and implementation strategies to promote PrEP acceptance among MSM.

scholarly journals Sexually transmitted infection diagnoses, sexualised drug use and associations with pre-exposure prophylaxis use among men who have sex with men in the UK

2020 ◽  
Vol 31 (3) ◽  
pp. 254-263
Author(s):  
Matthew P Hibbert ◽  
Caroline E Brett ◽  
Lorna A Porcellato ◽  
Vivian D Hope
Keyword(s):  
Drug Use ◽  
Sexually Transmitted Infection ◽  
Transmitted Infection ◽  
Cross Sectional ◽  
Sexually Transmitted ◽  
Factors Associated ◽  
Hiv Test ◽  
Condomless Anal Intercourse ◽  
Sex With Men ◽  
Exposure Prophylaxis

Previous research has focused on acceptability of pre-exposure prophylaxis (PrEP) use, but few community-based studies have been conducted regarding actual use, and PrEP use in the context of sexualised drug use remains understudied. A national online cross-sectional study recruited men who have sex with men (MSM) via social media (April–June 2018). Multivariable logistic regression was used to investigate factors associated with PrEP use. Bivariate analyses compared engaging in condomless anal intercourse (CAI) under the influence of specific drugs and recent sexually transmitted infection (STI) diagnoses (past 12 months) between MSM taking PrEP and those not. Overall, 6% (99/1581) MSM reported current PrEP use. Factors associated with PrEP use were increasing age, recent genitourinary medicine (GUM) attendance (95% versus 45%, aOR = 6.25, 95%CI 2.05, 19.03), an HIV test in the past three months (89% versus 23%, aOR = 14.22, 95%CI 6.76, 29.90), and recent engagement in chemsex (21% versus 4%, aOR = 3.56, 95%CI 1.78, 7.11). MSM taking PrEP were more likely to have had an STI diagnosis (42% versus 8%), most commonly chlamydia (26% versus 3%) and gonorrhoea (25% versus 4%). Considering the elevated levels of self-reported STI diagnoses among those on PrEP, there was a high level of engagement with sexual health services, which may help reduce onward STI transmission.

scholarly journals HIV infection among young men who have sex with men in China: comparison of risks among students and non-students

2019 ◽  
Author(s):  
Jing Wu ◽  
Zihuang Chen ◽  
Fei Yu ◽  
Youran Xu ◽  
Yue Ma ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Hiv Infection ◽  
Infection Rate ◽  
Multivariate Logistic Regression Analysis ◽  
Young Men ◽  
Multivariate Logistic Regression ◽  
Cross Sectional ◽  
Factors Associated ◽  
The Past ◽  
Sex With Men

Abstract Background The human immunodeficiency virus (HIV) epidemic has been drastically increasing among men who have sex with men (MSM) in China over the past decade. More so, the number of HIV infections among young adults in the country has also been on the rise, highlighting a unique sub-population, which may lead to increased incidence and transmission of the disease. This study aimed to determine the HIV infection rate amongst student and non-student young men who have sex with men (YMSM) in three regions in China and factors associated with their HIV infection. Methods A cross-sectional study was conducted from 1 September to 6 September 2017 in Beijing, Sichuan, and Guangzhou). Participants were recruited through a popular Chinese gay social networking application, as well as several college-based youth associations. Univariate and multivariate logistic regression analyses were conducted to assess factors associated with HIV infection. Results The HIV infection rate among non-student YMSM was significantly higher than that of student YMSM (10.3% versus 5.3%, χ2trend=17.34, P<0.001). The multivariate logistic regression analysis showed that YMSM self-identifying as homosexual (AOR=2.81, 95%CI=1.40-5.66, P=0.004) and perceived themselves at risk for HIV (AOR=3.08, 95:CI:1.33-7.15, P=0.009) had a 3 times increased odds of being HIV positive. Additionally, participants whom reported not always using condoms with sex partners in the past six months (AOR=1.69, 95%CI=1.17-2.44, P=0.006) were at increased odds of HIV infection. Conclusions Young men who have sex with men, particularly those identifying as homosexual and not always using condoms during intercourse, are at increased odds of HIV infection in China. Promoting comprehensive sexual education to youth and other measures aimed at improving HIV knowledge could help control HIV transmission among this key sub-population.

scholarly journals Authorship Correction: Factors Associated With Willingness to Use Pre-Exposure Prophylaxis in Brazil, Mexico, and Peru: Web-Based Survey Among Men Who Have Sex With Men

10.2196/15504 ◽  
2019 ◽  
Vol 5 (3) ◽  
pp. e15504 ◽  
Author(s):  
Thiago Silva Torres ◽  
Kelika A Konda ◽  
E Hamid Vega-Ramirez ◽  
Oliver A Elorreaga ◽  
Dulce Diaz-Sosa ◽  
...  
Keyword(s):  
Correction Factors ◽  
Web Based ◽  
Factors Associated ◽  
Sex With Men ◽  
Willingness To Use ◽  
Exposure Prophylaxis

scholarly journals Trends of HIV/Syphilis/HSV-2 seropositive rate and factors associated with HSV-2 infection in men who have sex with men in Shenzhen, China: A retrospective study

PLoS ONE ◽  
2021 ◽  
Vol 16 (5) ◽  
pp. e0251929
Author(s):  
Sha-Sha Mao ◽  
Shui-Dong Feng ◽  
Chen-Li Zheng ◽  
Wei Hu ◽  
Hao Li ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Sexual Behaviors ◽  
Control Measures ◽  
Trend Test ◽  
Related Factors ◽  
Seropositive Rate ◽  
Factors Associated ◽  
Laboratory Test Results ◽  
Significant Change ◽  
Sex With Men

Objectives To analyze the trends of HIV/syphilis/HSV-2 seropositive rate and explore the related factors with HSV-2 infection to provide the basis for adjusting STD intervention strategies and formulating prevention and control measures among MSM in Shenzhen. Methods Time-location sampling was conducted among MSM in Shenzhen in 2012, 2014, 2016, and 2018. Data on demographics, sexual behaviors and the laboratory test results of HIV, syphilis, HSV-2 were collected. The χ2 trend test was used to analyze the trends of HIV/syphilis/HSV-2 seropositive rate. The binary logistic regression model was used to explore the factors associated with HSV-2 infection. Results The seropositive rate of HIV fell significantly from 15.9% in 2012 to 8.7% in 2018 (Ptrend = 0.003), syphilis seropositive rate was significantly decreased from 20.4% in 2012 to 14.8% in 2018 (Ptrend = 0.025), HSV-2 seropositive rate had no significant change (16.7% in 2012 to 14.0% in 2018; Ptrend = 0.617). In principal component logistic regression analysis showed that FAC1_1 (X1 = Ever had sex with female, X2 = Gender of first sexual partner, X3 = Marital status, X4 = Age group), FAC2_1 (X5 = Education, X6 = Monthly income (RMB), X7 = Frequency of condom use in anal sex with men in the past 6 months), and FAC4_1 (X9 = History of STDs) were significantly associated with HSV-2 infection. Conclusions The seropositive rates of HIV and syphilis have dropped significantly but are still high. HSV-2 seropositive rate had no significant change and maintained a high level. It is necessary to continue strengthening HIV and syphilis interventions among MSM in Shenzhen. HSV-2 detection and intervention are urgently required for MSM, which might be another effective biological strategy further to control the HIV epidemic among MSM in Shenzhen.

scholarly journals Willingness to Use and Adhere to HIV Pre-Exposure Prophylaxis (PrEP) among Men Who Have Sex with Men (MSM) in China

2019 ◽  
Vol 16 (14) ◽  
pp. 2620 ◽  
Author(s):  
Liping Peng ◽  
Wangnan Cao ◽  
Jing Gu ◽  
Chun Hao ◽  
Jibin Li ◽  
...  
Keyword(s):  
Hiv Prevention ◽  
Factors Associated ◽  
On Demand ◽  
The Past ◽  
Different Types ◽  
Sex With Men ◽  
Long Acting ◽  
Willingness To Use ◽  
Exposure Prophylaxis ◽  
Oral Prep

This study aimed to investigate the levels of willingness to use pre-exposure prophylaxis (PrEP) and intention to adhere to PrEP and to further explore factors associated with PrEP uptake among men who have sex with men (MSM) in China. A total of 524 MSM were recruited from Chengdu, China. Half of the participants had heard of PrEP, and the awareness rate varied from 33.8%, 30.7%, and 7.1% for daily oral PrEP, on-demand PrEP, and long-acting injectable PrEP (LAI-PrEP), respectively. The overall willingness to use any type of PrEP in the next six months was 84.9% if PrEP is effective and provided for free. Participants were less likely to say that they would use PrEP if they used a condom consistently with their regular partners. However, participants were more likely to say that they would use PrEP if they had casual partners in the past month and had higher HIV prevention literacy. The majority of participants intended to adhere to PrEP prescription. More than forty percent (43.1%) of the participants reported that they might reduce condom use if they took PrEP. We found that the overall willingness to use PrEP was high among MSM living in China, but willingness varied across the different types of PrEP.

scholarly journals Alcohol consumption, substance use, and depression in relation to HIV Pre-Exposure Prophylaxis (PrEP) nonadherence among gay, bisexual, and other men-who-have-sex-with-men

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Paul A. Shuper ◽  
Narges Joharchi ◽  
Isaac I. Bogoch ◽  
Mona Loutfy ◽  
Frederic Crouzat ◽  
...  
Keyword(s):  
Substance Use ◽  
Logistic Regression ◽  
High Risk ◽  
Alcohol Consumption ◽  
Alcohol Use ◽  
Multivariate Logistic Regression ◽  
Harmful Alcohol ◽  
Sex With Men ◽  
Hiv Acquisition ◽  
Exposure Prophylaxis

Abstract Background Although HIV pre-exposure prophylaxis (PrEP) substantially diminishes the likelihood of HIV acquisition, poor adherence can decrease the HIV-protective benefits of PrEP. The present investigation sought to identify the extent to which alcohol consumption, substance use, and depression were linked to PrEP nonadherence among gay, bisexual, and other men-who-have-sex-with-men (gbMSM). Methods gbMSM (age ≥ 18, prescribed PrEP for ≥3 months) were recruited from two clinics in Toronto, Canada for an e-survey assessing demographics; PrEP nonadherence (4-day PrEP-focused ACTG assessment); hazardous and harmful alcohol use (AUDIT scores of 8–15 and 16+, respectively); moderate/high risk substance use (NIDA M-ASSIST scores > 4); depression (CESD-10 scores ≥10); and other PrEP-relevant factors. The primary outcome, PrEP nonadherence, entailed missing one or more PrEP doses over the past 4 days. A linear-by-linear test of association assessed whether increasing severity of alcohol use (i.e., based on AUDIT categories) was linked to a greater occurrence of PrEP nonadherence. Univariate logistic regression was employed to determine factors associated with PrEP nonadherence, and factors demonstrating univariate associations at the p < .10 significance level were included in a multivariate logistic regression model. Additive and interactive effects involving key significant factors were assessed through logistic regression to evaluate potential syndemic-focused associations. Results A total of 141 gbMSM (Mean age = 37.9, white = 63.1%) completed the e-survey. Hazardous/harmful drinking (31.9%), moderate/high risk substance use (43.3%), and depression (23.7%) were common; and one in five participants (19.9%) reported PrEP nonadherence. Increasing alcohol use level was significantly associated with a greater likelihood of nonadherence (i.e., 15.6, 25.0, and 44.4% of low-risk, hazardous, and harmful drinkers reported nonadherence, respectively (χ2(1) = 4.79, p = .029)). Multivariate logistic regression demonstrated that harmful alcohol use (AOR = 6.72, 95%CI = 1.49–30.33, p = .013) and moderate/high risk cocaine use (AOR = 3.11, 95%CI = 1.01–9.59, p = .049) independently predicted nonadherence. Furthermore, an additive association emerged, wherein the likelihood of PrEP nonadherence was highest among those who were hazardous/harmful drinkers and moderate/high risk cocaine users (OR = 2.25, 95%CI = 1.19–4.25, p = .013). Depression was not associated with nonadherence. Conclusions Findings highlight the need to integrate alcohol- and substance-focused initiatives into PrEP care for gbMSM. Such initiatives, in turn, may help improve PrEP adherence and reduce the potential for HIV acquisition among this group.

scholarly journals Factors associated with willingness to use Pre-exposure prophylaxis in Brazil, Mexico and Peru: an online survey among men who have sex with men (Preprint)

2019 ◽  
Author(s):  
Thiago Silva Torres ◽  
Kelika Konda ◽  
E. Hamid Vega-Ramirez ◽  
Oliver Antonio Elorreaga Reyes ◽  
Dulce Diaz-Sosa ◽  
...  
Keyword(s):  
Latin American ◽  
Online Survey ◽  
Sex Partners ◽  
Anal Sex ◽  
Factors Associated ◽  
Sex With Men ◽  
Prep Awareness ◽  
Willingness To Use ◽  
Exposure Prophylaxis ◽  
Oral Prep

BACKGROUND HIV epidemics disproportionally affect key populations including men who have sex with men (MSM). HIV prevalence among MSM varies from 17% in Brazil and Mexico to 13% in Peru, while it is below 0.5% for the general population. Pre-exposure prophylaxis (PrEP) with daily oral emtricitabine/tenofovir is being implemented in the context of combination HIV prevention. Reports on PrEP awareness, willingness to use, and acceptability among MSM have started to emerge over the last few years. Previously reported factors associated with willingness to use PrEP include: awareness, low cost, higher sexual risk behavior, prior sexually transmitted infection, and unwillingness to use condoms. OBJECTIVE This study aims to evaluate the factors associated with willingness to use daily oral PrEP among MSM in three Latin American, middle-income countries (Brazil, Mexico and Peru). METHODS This online cross-sectional survey was advertised in two gay social network apps (Grindr and Hornet) used by MSM to find sex partners and on Facebook during two months in 2018. Inclusion criteria were ≥18 years of age, cisgender men, and HIV-negative by self-report. Eligible individuals answered questions on: demographics, behavior, and PrEP (awareness, willingness to use, barriers and facilitators). Multivariable logistic regression modeling was performed to assess the factors associated with willingness to use daily oral PrEP in each country. RESULTS From a total sample of 43,687 individuals, 19,457 (45%) MSM were eligible and completed the online survey (Brazil: 58%, Mexico: 31%, Peru: 11%); median age was 28 years (IQR: 24-34), almost half lived in large urban cities and 89% self-defined as homosexual. Most of the participants were recruited on Grindr (69%). Almost 20% had never tested for HIV and condomless receptive anal sex was reported by 46% in the previous 6 months. A total of 13,110 (67%) would be eligible for PrEP (adapted from WHO risk criteria), but only 10% of participants had high HIV risk perception. PrEP awareness was reported by 65%, this was lower in Peru (46%). Overall, willingness to use PrEP was reported by 64%, highest in Mexico (70%) and lowest in Peru (58%). In multivariate regression models adjusted for age, schooling, and income: in each country willingness to use PrEP was positively associated with PrEP awareness and PrEP facilitators (e.g. free PrEP and HIV testing), and negatively associated with behavioral (e.g., concerned by daily pill regimen) and belief barriers (e.g., sex partners may expect condomless anal sex). CONCLUSIONS In this first cross-country online survey in Latin America, willingness to use PrEP was found to be high and directly related to PrEP awareness. Interventions to increase awareness and PrEP knowledge about safety and efficacy are crucial to increase PrEP demand. This study provides important information to support the implementation of PrEP in Brazil, Mexico and Peru.

scholarly journals Congruence between Hypothetical Willingness to Use Pre-Exposure Prophylaxis (PrEP) and Eligibility: An Online Survey among Belgian Men Having Sex with Men

2019 ◽  
Vol 16 (22) ◽  
pp. 4411 ◽  
Author(s):  
Bullinger ◽  
Reyniers ◽  
Vuylsteke ◽  
Laga ◽  
Nöstlinger
Keyword(s):  
Risk Perception ◽  
Online Survey ◽  
Univariate Analysis ◽  
Eligibility Criteria ◽  
Partner Status ◽  
Factors Associated ◽  
Dating Apps ◽  
Sex With Men ◽  
Willingness To Use ◽  
Exposure Prophylaxis

Men who have sex with men (MSM) are at high risk for acquiring HIV in Belgium. This study explores MSMs’ hypothetical willingness to use pre-exposure prophylaxis (PrEP), assesses it against formal PrEP eligibility criteria, and identifies factors associated with incongruence between eligibility and willingness. We used data from an online survey of n = 1444 self-reported HIV-negative MSM. Participants were recruited through social media of MSM organizations and dating apps. Univariate analysis described PrEP willingness and eligibility; bivariate analyses examined how specific co-variates (socio-demographic, knowledge-related, and attitudinal and behavioral factors) were associated with eligibility and willingness. About 44% were eligible for PrEP and about 70% were willing to use it. Those who were eligible were significantly more likely be willing to take PrEP (p < 0.001). Two incongruent groups emerged: 16% of eligible participants were unwilling and 58% of ineligible participants were willing to use PrEP. Factors associated with this incongruence were sexual risk behavior, HIV risk perception, partner status, PrEP knowledge, and attitudinal factors. Because the two groups differ in terms of profiles, it is important to tailor HIV prevention and sexual health promotion to their needs. Among those at risk but not willing to take PrEP, misconceptions about PrEP, and adequate risk perception should be addressed.

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