scholarly journals Association of mixed use of electronic and conventional cigarettes and exposure to secondhand smoke with prediabetes

2021 ◽  
Author(s):  
Seung Hoon Kim ◽  
Minah Park ◽  
Gyu Ri Kim ◽  
Sung-In Jang
Keyword(s):  
Secondhand Smoke ◽  
Multiple Logistic Regression Analysis ◽  
Fold Increase ◽  
Cigarette Use ◽  
The Past ◽  
Health And Nutrition ◽  
Mixed Use ◽  
Increased Risk ◽  
Never Smokers ◽  
Exposure To Secondhand Smoke

Abstract Objective To examine the association of mixed electronic and conventional cigarette use and exposure to secondhand smoke with prediabetes. Methods Data from the 2014–2018 Korean National Health and Nutrition Examination Survey were analyzed. Prediabetes was defined as an HbA1C of 5.7–6.4%. Participants were categorized according to type of cigarette use and secondhand smoke exposure. Multiple logistic regression analysis was performed. Results Of the 22,385 participants without diabetes, 6,735 had prediabetes. Mixed cigarette use was associated with a 1.57-fold increase in the odds of prediabetes when compared with never smoking without exposure to secondhand smoke (odds ratio [OR] = 1.57, 95% confidence interval [CI] = 1.31–1.87), and a 1.27-fold increase when compared with conventional cigarette use only (OR = 1.27, 95% CI = 1.09–1.49). Participants who were current non-smokers but mixed users in the past had an increased risk of prediabetes (OR = 1.54, 95% CI = 1.06–2.23). However, there was no significant association between current non-smoking but only conventional cigarette use in the past and prediabetes. Among never-smokers, exposure to secondhand smoke significantly increased the risk of prediabetes (OR = 1.15, 95% CI = 1.03–1.28). Conclusions Mixed use of electronic and conventional cigarettes and exposure to secondhand smoke increased the risk of prediabetes.

scholarly journals Association of mixed use of electronic and conventional cigarettes and exposure to second-hand smoke with prediabetes

2021 ◽  
Author(s):  
Seung Hoon Kim ◽  
Minah Park ◽  
Gyu Ri Kim ◽  
Hye Jin Joo ◽  
Sung-In Jang
Keyword(s):  
Glucose Metabolism ◽  
Electronic Cigarettes ◽  
Fold Increase ◽  
Population Based ◽  
Second Hand Smoke ◽  
Cigarette Use ◽  
Mixed Use ◽  
Increased Risk ◽  
Smoking Behaviors ◽  
Never Smokers

Abstract Context Despite previous studies regarding the association between smoking and diabetes, the effects of electronic cigarettes and second-hand smoke (SHS) on glucose metabolism and insulin sensitivity have not been fully elucidated. Objective To examine the association of mixed electronic and conventional cigarette use and exposure to SHS with prediabetes. Design Data from the 2014–2018 Korean National Health and Nutrition Examination Survey were analyzed. Setting Nationwide population-based Participants Of 39,199 participants, 22,385 participants (9,490 men, 12,895 women) without diabetes were included. The main independent variables were smoking behaviors, including exposure to SHS. Interventions None Main Outcome Measure(s) Prediabetes (HbA1C of 5.7–6.4%). Results Of 22,385 participants without diabetes, 6,735 had prediabetes. Mixed cigarette use was associated with a 1.57-fold increase in the odds of prediabetes when compared with never-smoking (odds ratio [OR]=1.57, 95% confidence interval [CI]=1.29–1.92) and a 1.27-fold increase when compared with conventional cigarette use only (OR=1.27, 95% CI=1.07–1.52). Participants who were current non-smokers but mixed users in the past had an increased risk of prediabetes (OR=1.54, 95% CI=1.04–2.13). There was no significant association between prediabetes and current non-smoking in individuals with previous conventional cigarette use only. Among never-smokers, exposure to SHS significantly increased the risk of prediabetes (OR=1.16, 95% CI=1.04–1.30). Conclusions Mixed use of electronic and conventional cigarettes and exposure to SHS increased the risk of prediabetes. Further studies are required to comprehensively investigate the molecular biology underlying the effects of previous and current mixed use of electronic cigarettes and SHS on glucose metabolism.

scholarly journals Exposure to Secondhand Smoke: Inconsistency between Self-Response and Urine Cotinine Biomarker Based on Korean National Data during 2009–2018

2021 ◽  
Vol 18 (17) ◽  
pp. 9284
Author(s):  
Boram Sim ◽  
Myung-Bae Park
Keyword(s):  
Secondhand Smoke ◽  
Vulnerable Groups ◽  
Exposure Rate ◽  
Short Term ◽  
The Past ◽  
Health And Nutrition ◽  
Urine Cotinine ◽  
Short Term Exposure ◽  
Shs Exposure ◽  
Exposure To Secondhand Smoke

This study aimed to estimate the secondhand smoke (SHS) exposure using urinary cotinine (UCo) to prove that the SHS exposure could not be properly assessed by self-reporting (SR). In total, 28,574 nonsmokers aged >19 years were selected from the Korean National Health and Nutrition Examination Survey data (2009–2018). First, changes in the annual concentration of UCo were analyzed, and the annual SHS exposure rates were measured based on SR and UCo from 2009 to 2018. Then, the average UCo concentration and UCo-measured SHS exposure rate were confirmed according to the subjects’ characteristics. Finally, factors associated with the UCo-measured SHS exposure rate were identified based on multiple regression analysis. The findings showed that the annual UCo concentrations and self-reported SHS exposure rates dropped significantly over the past decade. In contrast, the UCo-measured SHS exposure rate indicated that >80% of nonsmokers are still exposed to SHS. Moreover, we found vulnerable groups using UCo-measured SHS exposure rate. In particular, the self-reported SHS exposure at home and in workplaces and house type was highly associated with SHS exposure. Thus, these findings indicate that the actual SHS exposure could not be properly assessed by SR and should be verified using a biomarker, such as UCo. Considering that even a short-term exposure can be harmful to health, the goal of the policy should be to keep cotinine concentration as low as possible.

Cancer of the Lung, Larynx, and Pleura

2018 ◽  
Author(s):  
Jyoti Malhotra ◽  
Paolo Boffetta ◽  
Lorelei Mucci
Keyword(s):  
Lung Cancer ◽  
Secondhand Smoke ◽  
Lung Cancer Risk ◽  
Occupational Exposures ◽  
Men And Women ◽  
Established Risk Factor ◽  
Former Smokers ◽  
Never Smokers ◽  
Exposure To Secondhand Smoke ◽  
Cancer Of The Lung

Lung cancer is the most commonly diagnosed cancer among men in most countries, and is the primary cause of cancer death in men and women. Its epidemic increase in incidence began in the first half of the twentieth century, paralleling the uptake of cigarette smoking that occurred 20 years before. A series of landmark studies beginning in 1950 established tobacco as the primary cause of lung cancer. Current smokers have a 10- to 20-fold higher lung cancer risk compared to never smokers. Important for prevention, former smokers substantially reduce this excess risk 5 years after smoking cessation. Exposure to secondhand smoke, a well-established risk factor for lung cancer, has a 20%–25% higher risk for those exposed. There are several occupational exposures associated with lung cancer, including asbestos. Despite the success in defining lung cancer’s etiology, this highly preventable disease remains among the most common and most lethal cancers globally.

Abstract P295: Association Between Remained Number of Teeth and Cardiovascular Disease Among Korean Adults

Circulation ◽  
2018 ◽  
Vol 137 (suppl_1) ◽  
Author(s):  
Hong Seok Lee ◽  
Yong-Moon Park ◽  
Kyungdo Han
Keyword(s):  
Cardiovascular Disease ◽  
Total Cholesterol Level ◽  
Multiple Logistic Regression Analysis ◽  
Drinking Alcohol ◽  
Limited Evidence ◽  
Health And Nutrition ◽  
Income Status ◽  
Number Of Teeth ◽  
Increased Risk ◽  
The Relationship

Background: It has been reported that people with teeth loss have an increased risk of cardiovascular disease. However, there is limited evidence for the specific relationship between remained teeth and cardiovascular disease (CVD). Method: Among subjects who participated in Korea National Health and Nutrition Examination Survey conducted in 2008-2013, a total of 12,612 adults with mean age of 60.2±1.2 years old were analyzed. Number of teeth was classified as number less than 20, from 20 to 27 and more than 27. Multiple logistic regression analysis was performed to determine the relationship between cardiovascular disease and remained teeth number after adjusting for potential confounders. Result: The prevalence of cardiovascular disease was 6.5%, 3.3% and 1.4% respectively in groups having number less than 20, 20 to 27 and more than 27 ( P < 0.001). Total number of cardiovascular disease was 666. Diabetes, hypertension, total cholesterol level, waist circumference, metabolic syndrome had large proportion in a group having less than 20 teeth ( P < 0.001). People having less than 20 remained teeth had statistically significant cardiovascular disease after adjusting for age, sex, body mass index, smoking, drinking alcohol, exercise, education, income status, stress, diabetes, and hypertension. A group having less 20 teeth was likely to have statistically significant relationship with cardiovascular disease. (Odds ratio [OR]: 1.41, 95 % confidence interval [CI]: 1.06-1.89) and stroke (OR:1.90, CI:1.03-3.48). Conclusion: Our findings suggest that the number of remained teeth could be a useful additional indicator for assessing cardiovascular disease and stroke

scholarly journals Factors Associated with Celecoxib and Rofecoxib Utilization

2005 ◽  
Vol 39 (4) ◽  
pp. 597-602 ◽  
Author(s):  
Nigel SB Rawson ◽  
Parivash Nourjah ◽  
Stella C Grosser ◽  
David J Graham
Keyword(s):  
Cardiovascular Disease ◽  
Disease Burden ◽  
Multiple Logistic Regression Analysis ◽  
Underlying Disease ◽  
Nonsteroidal Antiinflammatory Drugs ◽  
Nonselective Nsaid ◽  
Antiinflammatory Drugs ◽  
The Past ◽  
Increased Risk ◽  
Cox 2

BACKGROUND: The cyclooxygenase-2 (COX-2) selective nonsteroidal antiinflammatory drugs (NSAIDs) celecoxib and rofecoxib (before its removal) are marketed as having fewer gastrointestinal (GI)-related complications than nonselective NSAIDs. However, adverse reaction data suggest that the use of COX-2 selective NSAIDs is associated with clinically significant GI events. OBJECTIVE: To assess whether patients receiving celecoxib and rofecoxib have a greater underlying disease burden than patients prescribed nonselective NSAIDs. METHODS: The study population consisted of members of 11 health plans, aged >34 years, with a pharmacy claim for celecoxib or rofecoxib or a nonselective NSAID dispensed between February 1, 1999, and July 31, 2001, who had been continuously enrolled for >364 days before the dispensing date. Celecoxib and rofecoxib patients were randomly selected without replacement from a pool of eligible users in each of the 30 months. Nonselective NSAID users were randomly chosen without replacement within each month on a 2:1 ratio to cases; they could be chosen in more than one month. Univariate analyses comparing 9000 cases and 18 000 controls were performed, followed by a multiple logistic regression analysis conditioned on time. RESULTS: Increasing age, treatment by a rheumatologist or an orthopedic specialist, treatment with a high number of different medications in the past year, treatment with oral corticosteroids in the past year, and having had a previous GI bleed increased the likelihood of receiving celecoxib or rofecoxib, whereas treatment with a high number of nonselective NSAID prescriptions in the past year decreased it. Treatment with a high number of different medications was a predictor of increased prevalence of underlying diabetes mellitus and cardiovascular disease. CONCLUSIONS: Patients having a greater underlying disease burden were more likely to receive COX-2 selective NSAIDs than nonselective ones. Paradoxically, patients at higher risk for cardiovascular disease were channeled toward treatment with COX-2 selective NSAIDs, many of which may confer an increased risk of acute myocardial infarction and other adverse cardiovascular outcomes.

Defining adult e-cigarette prevalence: comparing a categorical definition with days of use

2020 ◽  
pp. tobaccocontrol-2020-055641
Author(s):  
Raymond G Boyle ◽  
Sara Richter ◽  
Ann W St. Claire
Keyword(s):  
Young Adults ◽  
Cigarette Smoking ◽  
Population Based ◽  
Cigarette Use ◽  
Market Place ◽  
The Past ◽  
Never Smokers ◽  
Definition Of ◽  
Low Prevalence ◽  
Use Categories

IntroductionElectronic cigarette use has grown substantially and the health effects are being closely monitored. Tracking the evolving market place and the profile of adult users is important for tobacco control efforts; however, several different ways of measuring current use have been reported. This paper examines how well a categorical definition aligns with days of use.MethodsData from the 2018 Minnesota Adult Tobacco Survey assessed e-cigarette use based on days of use in the past month and currently using ‘every day, some days, or not at all’. Prevalence of current use and agreement of >1, >5 and >20 days of use with every day or some days were calculated.ResultsThe prevalence of e-cigarette use varied by category of use from 2.4% (≥20 days/30) to 6.0% (≥1 day/30). The highest prevalence was found among young adults reporting any use in the past 30 days (21.9%). Never smokers had low prevalence overall; however, 4.4% reported using in the past 30 days. Using at least 1 day in the past 30 days included a higher proportion of young adults (p<0.001) and never smokers (p<0.001) compared with other current use categories. Compared with every day or some days, the per cent agreement with days of use categories ranged from 89.7% to 94.4% and kappa ranged from 0.60 to 0.81.ConclusionsPrevalence and sociodemographics varied by definition of use. Asking ‘every day, some days or not at all’ in population-based studies has the advantage of aligning with cigarette smoking current use definition.

Secondhand smoke from electronic cigarette resulting in hypersensitivity pneumonitis

2020 ◽  
Vol 13 (3) ◽  
pp. e233381 ◽  
Author(s):  
Panagis Galiatsatos ◽  
Erin Gomez ◽  
Cheng Ting Lin ◽  
Peter B Illei ◽  
Pali Shah ◽  
...  
Keyword(s):  
Lung Injury ◽  
Secondhand Smoke ◽  
Hypersensitivity Pneumonitis ◽  
Electronic Cigarettes ◽  
Electronic Cigarette ◽  
Cigarette Use ◽  
Diagnostic Investigation ◽  
Health Related ◽  
The Usa ◽  
Exposure To Secondhand Smoke

Cases of vaping-induced lung injury have increased in the USA, resulting in a heterogeneous collection of pneumonitis patterns in persons who used electronic cigarettes. Hypersensitivity pneumonitis has been documented in several cases of first-hand electronic cigarette use; however, secondhand smoke health-related consequences have not been fully understood. We present a case of the patient who developed hypersensitivity pneumonitis secondary to exposure to secondhand smoke from electronic cigarette. We summarise the presentation and diagnostic investigation, as well as the management of this case.

scholarly journals E-Cigarette Use and Future Cigarette Initiation Among Never Smokers and Relapse Among Former Smokers in the PATH Study

2019 ◽  
Vol 134 (5) ◽  
pp. 528-536 ◽  
Author(s):  
Robert McMillen ◽  
Jonathan D. Klein ◽  
Karen Wilson ◽  
Jonathan P. Winickoff ◽  
Susanne Tanski
Keyword(s):  
Cigarette Smoking ◽  
Harm Reduction ◽  
Electronic Cigarettes ◽  
Computer Assisted ◽  
Cigarette Use ◽  
Cigarette Smokers ◽  
Potential Harm ◽  
Increased Risk ◽  
Never Smokers

Objectives: Any potential harm-reduction benefit of electronic cigarettes (e-cigarettes) could be offset by nonsmokers who initiate e-cigarette use and then smoke combustible cigarettes. We examined correlates of e-cigarette use at baseline with combustible cigarette smoking at 1-year follow-up among adult distant former combustible cigarette smokers (ie, quit smoking ≥5 years ago) and never smokers. Methods: The Population Assessment of Tobacco and Health Study, a nationally representative, longitudinal study, surveyed 26 446 US adults during 2 waves: 2013-2014 (baseline) and 2014-2015 (1-year follow-up). Participants completed an audio computer-assisted interview in English or Spanish. We compared combustible cigarette smoking at 1-year follow-up by e-cigarette use at baseline among distant former combustible cigarette smokers and never smokers. Results: Distant former combustible cigarette smokers who reported e-cigarette past 30-day use (9.3%) and ever use (6.7%) were significantly more likely than those who had never used e-cigarettes (1.3%) to have relapsed to current combustible cigarette smoking at follow-up ( P < .001). Never smokers who reported e-cigarette past 30-day use (25.6%) and ever use (13.9%) were significantly more likely than those who had never used e-cigarettes (2.1%) to have initiated combustible cigarette smoking ( P < .001). Adults who reported past 30-day e-cigarette use (7.0%) and ever e-cigarette use (1.7%) were more likely than those who had never used e-cigarettes (0.3%) to have transitioned from never smokers to current combustible cigarette smokers ( P < .001). E-cigarette use predicted combustible cigarette smoking in multivariable analyses controlling for covariates. Conclusions: Policies and counseling should consider the increased risk for nonsmokers of future combustible cigarette smoking use as a result of using e-cigarettes and any potential harm-reduction benefits e-cigarettes might bring to current combustible cigarette smokers.

scholarly journals Is exposure to secondhand smoke associated with current depression (PHQ-8) among never-smokers? Results from a survey among German adults

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Fabian Erdsiek ◽  
Patrick Brzoska
Keyword(s):  
Secondhand Smoke ◽  
Logistic Regression Model ◽  
German Health ◽  
Potential Association ◽  
Prevalence Of Depression ◽  
Patient Health ◽  
Shs Exposure ◽  
Interaction Term ◽  
Never Smokers ◽  
Exposure To Secondhand Smoke

Abstract Background Findings on the association between exposure to secondhand smoke (SHS) and depression are contradictory. Comparability of existing research is limited due to varied methods and measures. This study examines the potential association between exposure to SHS and depression and a potential moderation by sex using representative data from Germany. Methods For our study, we used data from the German Health Update (GEDA) 2014/2015 on n = 10,274 never-smokers. We calculated a logistic regression model with an interaction term for potential sex-exposure interactions. We used the self-reported duration of exposure to predict current depression of any type as defined by the Patient Health Questionnaire PHQ-8 (score ≥ 10), accounting for a large number of confounders. Results In our sample, prevalence of depression was 8.8% in women and 5.3% in men. 90.4% were never or almost never exposed to SHS, while 7.1% were exposed < 1 h per day and around 2.5% reported being exposed for ≥1 h per day. While SHS exposure for < 1 h per day was not associated with current depression (OR = 1.54; 95%-CI: 0.93–1.61), SHS exposure for at least 1 h per day was associated with increased odds for current depression (OR = 1.59; 95%-CI: 1.08–2.35). No sex-specific differences were found. Conclusions Higher levels of SHS exposure are associated with current depression, although the nature and direction of the association are still unclear. We identified no differences in the association between men and women. More studies, particularly using longitudinal data, are needed to determine the nature of the association.

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