scholarly journals The Effect of Benign Joint Hypermobility on Pain, Physical Function and Quality of Life in Patients with Knee Osteoarthritis

2021 ◽  
Author(s):  
Serap Satis
Keyword(s):  
Quality Of Life ◽  
Body Mass Index ◽  
Knee Osteoarthritis ◽  
Physical Function ◽  
Body Mass ◽  
Sf 36 ◽  
The Difference ◽  
Group 2 ◽  
Group 1

Abstract Objective: This study investigated the effect of hypermobility on pain, joint stiffness, physical function, and quality of life in patients with knee osteoarthritis. Design: Sixty-four patients diagnosed with bilateral knee osteoarthritis were included; 42 patients in Group 1 were those with hypermobility and 22 patients in Group 2. There were 40 women and 2 men in Group 1, and 16 women and six men in Group 2 were those without hypermobility. The age, sex, and body mass index of all patients recorded. The WOMAC and SF-36 tests performed on the patients.Results: The average ages were 51.40±5.42 and 53.36±4.31, respectively, and there was no statistically significant difference. The body mass index was high in the hypermobility group, and the difference was statistically significant (p=0.028). Pain and stiffness were higher in the hypermobility group than in the non-hypermobility group in the WOMAC subgroups and total scores (p=0.030, p=0.002, p=0.047). The non-hypermobility group had better SF-36 social function and pain scale scores. The difference was statistically significant (p=0.016, p=0.004).Conclusions: Hypermobility aggravates the symptoms of knee osteoarthritis. Hypermobility evaluated in all patients diagnosed with knee OA. A more intense and long-term rehabilitation program should be determined for these patients to prevent injuries and improve proprioception.

scholarly journals Neuropathic pain in knee osteoarthritis

2021 ◽  
Vol 61 (1) ◽  
Author(s):  
Uğur Güngör Demir ◽  
Ali Nail Demir ◽  
Naciye Füsun Toraman
Keyword(s):  
Quality Of Life ◽  
Body Composition ◽  
Neuropathic Pain ◽  
Knee Osteoarthritis ◽  
Physical Function ◽  
Body Mass ◽  
Symptom Duration ◽  
Group 2 ◽  
Group 1

Abstract Background This study aimed to investigate the relationship between the neuropathic pain in knee osteoarthritis with the body composition, anthropometric and postural features, physical function, and quality of life. Methods Patients with primary knee osteoarthritis, 50–70 years of age, were included in the study and divided into Group 1 with neuropathic pain and Group 2 with no neuropathic pain according to Douleur Neuropathique-4. The groups were compared in terms of demographic, clinical, radiological, laboratory findings and anthropometric measurements, body composition, physical function tests, osteoarthritis severity, quality of life, and posturography. Results 200 patients were included in the study. 98 (82.6% female) were in Group 1 and 102 (74.5% female) in Group 2. Age was higher in Group 1 compared to Group 2 [61 (50–70) and 57.5 (50–70), respectively, p = 0.03]. Symptom duration was also longer in Group 1 (5.21 ± 4.76 and 3.38 ± 3.58, p = 0.002). Body mass indices were 31.9 ± 5.6 and 30.1 ± 4.8 (p = 0.015). Kellgren–Lawrence class, Western Ontario and McMaster Osteoarthritis Index and Short Form-36 scores were more unfavorable in Group 1. Although fall risk was similar, stability and Fourier harmony indices were impaired in Group 1 compared to Group 2 especially when the visual and proprioceptive input was blocked. Conclusions Almost half of the patients with knee osteoarthritis had neuropathic pain which was associated with longer symptom duration and higher age, lower education, higher body mass index, more severe radilogical findings, worse pain perception, lower physical function and quality of life, and lower stability.

TREATMENT OF A COMBINATION OF DIABETIC POLYNEUROPATHY WITH TYPE 2 DIABETES AND GOUT

2021 ◽  
Vol 7 (3) ◽  
pp. 24-27
Author(s):  
S. Tokareva ◽  
R. Kupeev ◽  
Aleksandr Hadarcev ◽  
Sof'ya Belyaeva
Keyword(s):  
Quality Of Life ◽  
Glycosylated Hemoglobin ◽  
Fasting Blood Glucose ◽  
Diabetic Polyneuropathy ◽  
Sf 36 ◽  
Effect Of Therapy ◽  
Male Patients ◽  
Group 2 ◽  
Group 1

The purpose of the work. To show the expediency of using a complex DPN therapy with thio-gammoy-600 in combination with TPP, B12-ankerman and febuxostat. Materials and research methods. The study involved 28 male patients suffering from DM2 aged 56-77 years, with an av-erage age of 64.6±0.7 years. The initial values of average fasting blood glucose were 7.8 ± 1.52 mmol/l, glycosylated hemoglobin 7.4 ± 0.13%. Two groups were identified: group 1 (main) – 14 people and group 2 (control) - 16 people. In group 2, basic DPN therapy was used (thiogamma 600 mg/day for 4 months). For the first 14 days, the drug was administered intravenously, and then administered orally. In group 1, in addition to basic DPN therapy, B12-ankerman and febuxostat (adenuric) – 80 mg/day were received. TPP was carried out on a portable device TPP-03 for 15 minutes daily. This treatment regimen was used for 4 months. The assessment of the quality of life (QL) was carried out using the MOS SF-36 questionnaire. Results and their discussion. Four months after the start of therapy, more pronounced changes were observed in patients of the first group. The total score of the NSS scale in this group increased by 28.9%, and in group 2 - by 18.8%. The positive effect of therapy with adenuric and TES on the course of DPN shows that the use of this treatment will naturally lead to an improve-ment in the quality of life of patients, the dynamics of which was studied according to the results of the SF-36 questionnaire.

Abstract 103: Determinants of Quality of Life in Permanent Pacemaker Patients: a Cross-Sectional Analysis

2014 ◽  
Vol 7 (suppl_1) ◽  
Author(s):  
Rhanderson N Cardoso ◽  
Daniel Garcia ◽  
Alexandre Benjo ◽  
Francisco Macedo ◽  
Cesar Benjo ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Body Mass Index ◽  
Body Mass ◽  
Well Being ◽  
Permanent Pacemaker ◽  
Smoking History ◽  
Categorical Variables ◽  
Cross Sectional ◽  
Sf 36

Background: Permanent pacemakers (PPM) have improved cardiovascular outcomes and quality of life (QoL) in patients with a wide variety of cardiac rhythm disturbances. Nevertheless, misperceptions about the safety of daily activities (SODA) and associated factors can compromise patients’ absolute well-being. We aimed to study factors associated with worst QoL in PPM patients. Methods: PPM patients from a tertiary hospital answered an 18-question questionnaire about their perception on the SODA, which was scored based on misperception rate. Patients also answered SF-36, a validated QoL questionnaire which is scored from 0 to 100 on each of its 8 scales. Baseline characteristics were compared to average on SF-36 scales in a cross-sectional model by t-test for categorical variables and by univariable regression for continuous variables. Statistical analysis was done with Stata software 10.0 (Texas). Results: A total of 75 PPM patients aged 65.3±12 years were included, of which 31 (41%) were males. Most common reason for PPM was 3rd degree atrioventricular block (44%). Body mass index (p=0.019) and misperception rate on SODA (p=0.003) presented a significant negative regression coefficient with SF-36 average. Age, gender, average income, Chagas disease etiology, diabetes, hypertension, ejection fraction, NYHA classification, previous myocardial infarction (MI), smoking history and peripheral vascular disease were not significantly associated with SF-36 QoL results. Conclusions: In a cross-sectional study, body mass index and misperceptions about the safety of daily-life activities were associated with worst quality of life in patients with permanent pacemaker. These results suggest that optimal physician education of patients and their families about the SODA for PPM patients may ultimately improve patients’ well-being.

scholarly journals The Effect of Physical Activity and High Body Mass Index on Health-Related Quality of Life in Individuals with Metabolic Syndrome

2020 ◽  
Vol 17 (10) ◽  
pp. 3728
Author(s):  
Alba Marcos-Delgado ◽  
Tania Fernández-Villa ◽  
Miguel Ángel Martínez-González ◽  
Jordi Salas-Salvadó ◽  
Dolores Corella ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Metabolic Syndrome ◽  
Body Mass Index ◽  
Body Mass ◽  
Health Related Quality ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related

The main objective of this study was to examine the relationship between the level of physical activity (PA) and the degree of obesity with health-related quality of life (HRQoL) in individuals with metabolic syndrome (MetS) who participated in the Predimed-Plus study. A total of 6875 subjects between 55 and 75 years of age with MetS were selected and randomized in 23 Spanish centers. Subjects were classified according to categories of body mass index (BMI). PA was measured with the validated Registre Gironí del Cor (REGICOR) questionnaire and subjects were classified according to their PA level (light, moderate, vigorous) and the HRQoL was measured with the validated short-form 36 (SF-36) questionnaire. By using the ANOVA model, we found a positive and statistically significant association between the level of PA and the HRQoL (aggregated physical and mental dimensions p < 0.001), but a negative association with higher BMI in aggregated physical dimensions p < 0.001. Furthermore, women obtained lower scores compared with men, more five points in all fields of SF-36. Therefore, it is essential to promote PA and body weight control from primary care consultations to improve HRQoL, paying special attention to the differences that sex incurs.

scholarly journals Assessment of the health related quality of life in patients suffering from hypertension and diabetes mellitus: A cross sectional study

2016 ◽  
Vol 15 (1) ◽  
pp. 84-89 ◽  
Author(s):  
Ishtpreet Mann ◽  
Manisha Khubber ◽  
Ashwani K Gupta ◽  
Prithpal Singh Matreja ◽  
Harbir K Rao
Keyword(s):  
Quality Of Life ◽  
Diabetes Mellitus ◽  
Health Related Quality ◽  
Cross Sectional ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related ◽  
Group 2 ◽  
Group 1

Background: Diabetes mellitus and hypertension are chronic disorders, inadequate management of these two disorders leads to several complications and end organ damage that can impair health related quality of life (HRQoL) in these individuals. Several studies in hypertensive patients concluded that hypertension reduced HRQoL and participants with diabetes also reported comparably decreased HRQoL. The data on HRQoL in patients suffering from both hypertension and diabetes is limited hence we designed this study to assess health related quality of life in patients suffering from hypertension and diabetes mellitus.Methodology: This single centre, cross-sectional study was conducted for 2 months between April and August 2013 in patients with hypertension and diabetes mellitus. Patients suffering from hypertension were recruited in study and were divided into two groups, Group 1 consisted of patient suffering from hypertension and diabetes mellitus whereas Group 2 consisted of patients suffering from hypertension. Patients were assessed on Short form health Survey (SF-36) and the WHOQOL – Bref scores. Results: A total of 85 patients were screened out of which 41 patients were enrolled in the study, 21 patients in Group 1 and 20 patients in group 2. The SF-36 Scores showed significantly (p<0.05) worse pain scores in patients in Group 2. Patients in Group 1 had a better quality of life as compared to other group as evident by higher scores in most of the parameters of SF-36 and WHO-QOL Bref Score, though it was not statistically significant. Conclusion: Both groups had compromised quality of life; patients with hypertension and diabetes had a better quality of life.Bangladesh Journal of Medical Science Vol.15(1) 2016 p.84-89

Effect of cortexin on the quality of life in the early rehabilitative period after hemispheric ischemic stroke

2016 ◽  
Vol 94 (2) ◽  
pp. 138-143
Author(s):  
Ludmila A. Belova ◽  
V. V. Mashin ◽  
V. V. Abramova ◽  
A. N. Proshin ◽  
A. N. Ovsyannikova
Keyword(s):  
Quality Of Life ◽  
Ischemic Stroke ◽  
Low Dose ◽  
Neuroprotective Effect ◽  
Control Group ◽  
Sf 36 ◽  
Group 2 ◽  
And Control ◽  
Group 1

Aim. To study the neuroprotective effect of a repeated course of low dose cortexin therapy on the quality of life in the early rehabilitative period after hemispheric ischemic stroke (IS). Materials and methods. 90 patients were divided into group 1 treated with cortexin (10 mg i/m twice daily (morning and afternoon) in addition to basal treatment, group 2 given the repeated course of the same treatment, and control group (basal therapy alone). The standard SF-36 questionnaire was used to assess the quality of life. Results. Treatment of patients following acute hemispheric ischemic stroke with cortexin (10 mg i/m twice daily) and the repeated course of the same treatment after 10 days resulted in the accelerated and more complete normalization of the quality of life in the early rehabilitation petriod (starting from days 21-27 days after the onset of disease) than in the patients given a single course of cortexin therapy or basal treatment alone.

scholarly journals Body mass index and quality of life among students aged nineteen to twenty two years

2019 ◽  
Vol 12 (22) ◽  
pp. 13-17
Author(s):  
Nada Arseni ◽  
Hans-Eric Reitmayer
Keyword(s):  
Quality Of Life ◽  
Body Mass Index ◽  
Physical Education ◽  
Body Mass ◽  
Short Form ◽  
The Body ◽  
Male Students ◽  
Sf 36 ◽  
Short Form Health

AbstractAim: The purpose of this research is to identify and analyze the association of the Body Mass Index (BMI) and quality of life (QoL) components in students aged 19 to 22 that attended physical education classes once a week during a whole semester. The students come from different faculties of the West University of Timişoara.Methods: The research was conducted during the physical education classes to which they participated during one semester. The research has begun in October 2018 and ended in January 2019. A total of 400 students were asked to participate in this study, 200 female and 200 male students. As research methods, we used the RAND 36 Item Short Form Health Survey SF-36 questionnaire to assess the quality of life, as well as the statistical-mathematical method.Results: Our results showed that 66% of the students had a normal BMI, 12% are underweight, 17% are overweight and 12% are obese. It has been found that the quality of life score does not depend on the body mass index. No correlation has been found between the QOL total score and BMI in neither male students r=0.035, R²=0.0012, p=0.62, nor female students r=-0.01, R²<0.001, p=0.88.

scholarly journals Correction of vaginal microbiota in patients in early and late transition to menopause

2020 ◽  
pp. 130-136
Author(s):  
L. Yu. Karakhalis ◽  
Yu. S. Ponomareva ◽  
N. S. Ivantsiv
Keyword(s):  
Quality Of Life ◽  
Local Therapy ◽  
Menopausal Transition ◽  
Combined Approach ◽  
Statistical Studies ◽  
The Difference ◽  
Group 2 ◽  
Late Transition ◽  
Group 1

Introduction: to investigate the possibility of using clindamycin and butaconazole in local therapy of moderate and severe dysbiosis in patients during the menopausal transition (early and late).Materials and methods: 107 women were examined. They were divided into two groups depending on their complains: the patients of group 1 (49.5%) had an early transition to menopause (44.7 ± 2.3 years); the patients of group 2 (50.5%) corresponded to a late transition to menopause (49.1 ± 1.5 years). The complains were evaluated. The levels of hormones (FSH, AMH, Inhibin B, estradiol) were determined. A study of the vaginal biotope was conducted by PCR ‘Femoflor 8. Statistical studies were conducted in the environment of STATISTICA 10 package (Tibco, USA). The difference in average values was considered statistically significant for p<0.05. Results: vegetative-vascular disorders were typically for patient in group 2 and detected in 74.1%. Mucosal dryness was 5.2 times more common in patients 2 group, as was dyspareunia (5.5 times more often), dysuria (14 times more often), itching in the vagina (3.5 times more often), discomfort (3.4 times often). All patient in group 2, and 51% of patient in group 1 had moderate and severe dysbiosis on the background of hypoestrogenia.Conclusion: The period of menopausal transition is characterized as a abnormalities of the vaginal biotope due to the activation of aerobes, anaerobes, and fungi of the genus Candida, and estrogen deficiency, that is more pronounced in patients with a late transition to menopause. Combined approach to the therapy these disorders allows to level out the clinical manifestation due to the consistent use of Clindacin B prolong and Ovipol Clio, but also improve the quality of life by individually selecting the duration estradiol therapy.

scholarly journals Comparative characteristics of the quality of life of asthma patients with different types of airway hyperresponsiveness to physical stimules

2021 ◽  
pp. 55-61
Author(s):  
N. L. Perelman
Keyword(s):  
Quality Of Life ◽  
Airway Hyperresponsiveness ◽  
Group 4 ◽  
Sf 36 ◽  
Different Types ◽  
Asthma Patients ◽  
Group 3 ◽  
Group 2 ◽  
Group 1

Aim. To compare the nature and degree of influence of different types of airway hyperresponsiveness (AHR) on the general and specific quality of life (QoL) of patients with asthma and control over the disease.Materials and methods. 234 patients with mild-to-moderate asthma, aged from 18 to 60 years old, were interviewed and examined. Depending on the presence of one or another type of AHR, 4 groups were formed: group 1 included 60 patients with cold AHR, group 2 – 75 patients with hypoosmotic AHR, group 3 – 35 patients with hyperosmotic AHR, group 4 – 64 patients with exercise-induced bronchoconstriction (EIB). QoL and the state of the emotional sphere were assessed using the SF-36, AQLQ, HADS questionnaires. The level of asthma control was determined using the ACT questionnaire. Lung function was assessed by spirometry.Results. When comparing QoL between groups, statistical differences were obtained for most of the SF-36 scales, with the exception of the domains “Role Physical” (RP) and “Bodily Pain” (BP), and their presence and significance varied depending on the types of AHR being compared. The lowest QoL indices were found in group 1 of patients with cold AHR according to the domains “Physical Activity” (PA), RP, BP, and “Role Emotional” (RE). The lowest indices for the domains “General Health” (GH), “Vitality” (V) and “Mental health” (MH) were found in the respondents of the 2nd group. Most of the highest QoL indicators in the compared groups were found in patients of group 4 with EIB in the domains PA, RP, V, RE, and MH. When carrying out a comparative analysis, the maximum number of significant differences was found between the groups with cold AHR and EIB. A comparative study of QoL using a special AQLQ questionnaire showed the lowest indices for the “Activity” and “Symptoms” domains in groups 1 and 2 of asthma patients. In addition, in group 1, the minimum QoL values were recorded for the “General QoL” domain (3.6±0.2 points), and in group 2, for the “Environment” domain (2.9±0.3 compared with 3.9±0.2 points in group 3, p<0.01).Conclusion. This study has demonstrated the multifaceted effect of AHR on health-related QoL, dependent on sensitivity to a particular physical stimulus and the season of maximum trigger action. The subjective assessment of psychosocial functioning is most differentiated according to the GH domain of the SF-36 questionnaire. The greatest negative impact on the QoL indices is exerted by the cold and hypoosmotic AHR, the least – by the EIB. The assessment of QoL allows to get a full picture of the perception of the patient's health level at the moment and in the given conditions.

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