scholarly journals Strengthening the Construction of Pathology Department of Chinese Primary Hospitals is an Urgent Task

2021 ◽  
Author(s):  
Ke Chen ◽  
xiangling meng ◽  
Zhengguang Wang
Keyword(s):  
Rare Disease ◽  
Treatment Effect ◽  
Pseudomyxoma Peritonei ◽  
Pathological Examination ◽  
Imaging Diagnosis ◽  
Case Presentation ◽  
Laparoscopic Exploration ◽  
Pathology Department ◽  
Urgent Task ◽  
Abdominal Exploration

Abstract Background: pseudomyxoma peritonei(PMP) is a rare disease, the incidence of occult, mainly occurs in the appendix, ovary, etc., generally speaking, the progress is slow, through imaging diagnosis is more difficult, and the symptoms are not typical, often found in abdominal exploration, the treatment effect is relatively poor. Because PMP is often secondary to appendectomy, it is particularly important to make a careful pathological examination of the specimen after appendectomy. Case presentation: This case is a middle-aged and elderly man. Seven years after appendectomy, the specimen was confirmed as PMP by pathology after laparoscopic exploration. Later, the specimen 7 years ago was reexamined and pathological examination showed that the tumor was composed of mucinous cells. Conclusions: This puts forward higher requirements for the construction of pathology department in China's primary hospitals.

scholarly journals Appendicular mucinous adenocarcinoma associated with pseudomyxoma peritonei, a rare and difficult imaging diagnosis.

2016 ◽  
Vol 18 (2) ◽  
pp. 257 ◽  
Author(s):  
Romeo Ioan Chira ◽  
Codrut Cosmin Nistor-Ciurba ◽  
Andreea Mociran ◽  
Petru Adrian Mircea
Keyword(s):  
Computed Tomography ◽  
Family History ◽  
Rare Disease ◽  
Male Patient ◽  
Pseudomyxoma Peritonei ◽  
Mucinous Adenocarcinoma ◽  
Peritoneal Lavage ◽  
Mucinous Carcinoma ◽  
Imaging Diagnosis ◽  
History Of

Pseudomyxoma peritonei (PMP) is a rare disease, caused by primary mucinous tumors that arise most frequently from appendix, ovary, or pancreas. Usually diagnosis is made by computed tomography, but ultrasonography can be a very useful imagistic method, if this diagnosis is taken into account by the observer. We present a case of a PMP caused by an appendiceal mucinous carcinoma, in a 34-year-old male patient, with family history of malignancies, diagnosed in our department. He was thereafter surgically treated - appendiceal resection, peritoneal lavage - followed by chemotherapy. We underline the importance of ultrasonography, even though at first encounter, the diagnosis of PMP being generally difficult.

scholarly journals Refractory pharyngeal ulceration due to cytomegalovirus in a patient with HIV infection: a case report and literature review

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Morichika Osa ◽  
Akihiro Sato ◽  
Maki Sakagami ◽  
Masaki Machida ◽  
Takao Sato ◽  
...  
Keyword(s):  
Hiv Infection ◽  
Pathological Examination ◽  
Cmv Infection ◽  
Case Presentation ◽  
Immunodeficiency Virus ◽  
Before And After ◽  
Infected Cells ◽  
Immunocompromised Hosts ◽  
Inflammatory Syndrome ◽  
Nonspecific Inflammation

Abstract Background Cytomegalovirus (CMV) is an important pathogen among immunocompromised hosts. Typically, CMV in human immunodeficiency virus (HIV) infection causes diseases of the retina, digestive tract, lungs and liver, but there are few cases of CMV infection of the pharynx and larynx. Case presentation A 57-year-old man with HIV infection was admitted because of pharyngeal pain. Before and after admission, pharyngeal biopsies guided by laryngeal endoscopy were performed four times, but pathological examination showed nonspecific inflammation, and the cause of pharyngeal ulceration was unclear. Additionally, the ulceration deteriorated after initiation of retroviral therapy. Laryngomicrosurgery was conducted under general anesthesia to remove tissue, and pathological diagnosis confirmed CMV infection. Pathological features included enlargement of the cytoplasm and nucleus in infected cells, and intranuclear bodies called owl’s eye inclusions. Ganciclovir dramatically improved the symptoms and laryngoscopic findings. Conclusions This case was diagnosed as pharyngitis and pharyngeal ulceration caused by CMV infection, related to immune reconstitution inflammatory syndrome. In previous reports of CMV-induced pharyngeal or laryngeal ulceration in HIV infection, we found six cases similar to our present case. All cases were diagnosed by biopsy. The present case indicates the importance of biopsy for definitive diagnosis. CMV infection should be considered as a differential diagnosis of pharyngeal ulceration in patients with HIV infection.

scholarly journals Uncommon manifestations of a rare disease: a case of autoimmune GFAP astrocytopathy

BMC Neurology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Hong Di ◽  
Yue Yin ◽  
Ruxuan Chen ◽  
Yun Zhang ◽  
Jun Ni ◽  
...  
Keyword(s):  
Rare Disease ◽  
Hormone Secretion ◽  
White Matter Lesions ◽  
Signs And Symptoms ◽  
Careful Examination ◽  
Case Presentation ◽  
Inappropriate Antidiuretic Hormone Secretion ◽  
Contrast Enhanced ◽  
The Central Nervous System ◽  
Magnetic Resonance Imaging Mri

Abstract Background Manifestations of intractable hyponatremia and hypokalemia in autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy have been rarely reported. Case presentation A 75-year-old male patient presented as the case of syndrome of inappropriate antidiuretic hormone secretion (SIADH) and intractable hypokalemia, showed fever, fatigue, and mental disorders. Signs and symptoms of meningoencephalitis, ataxia, and cognitive abnormalities. Magnetic resonance imaging (MRI) revealed multiple white matter lesions of the central nervous system. He had GFAP-IgG in the cerebrospinal fluid (CSF). After treatment with corticosteroids, his symptoms were alleviated gradually, and the level of electrolytes was normal. However, head contrast-enhanced MRI + susceptibility-weighted imaging (SWI) showed a wide afflicted region, and the serum GFAP-IgG turned positive. Considering the relapse of the disease, ha was treated with immunoglobulin and mycophenolate mofetil (MMF) to stabilize his condition. Conclusion This case showed a rare disease with uncommon manifestations, suggesting that careful examination and timely diagnosis are essential for disease management and satisfactory prognosis.

scholarly journals Oesophageal squamous cell carcinoma mimicking submucosal tumour

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Wen Wang ◽  
Dazhou Li ◽  
Linfu Zheng ◽  
Hongli Zhan
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Squamous Epithelium ◽  
Pathological Examination ◽  
Muscularis Mucosa ◽  
Case Presentation ◽  
Duct Epithelium ◽  
Tumour Spread ◽  
Positron Emission

Abstract Background Oesophageal submucosal tumours are usually benign. We report a rare case of esophageal squamous cell carcinoma presenting as a submucosal tumour. Case presentation A 58-year-old man undergoing screening oesophago-gastroduodenoscopy was found to have a smooth-surfaced 0.6-cm sized submucosal tumour in the oesophagus 30 cm from the incisor. Endoscopic ultrasonography showed the tumour to be located in the muscularis mucosa; the lesion was heterogeneously hypoechoic and had a clear boundary. With a provisional diagnosis of leiomyoma, the tumour was removed by endoscopic submucosal dissection. Pathological examination showed it to be a moderately differentiated infiltrating squamous cell carcinoma, with normal overlying squamous epithelium. Immunohistochemistry indicated that it was caused by malignant transformation in mucosal glandular duct epithelium. Positron emission tomography–computer tomography showed no tumour spread to any other site. The patient was treated by oesophageal resection. Conclusion The clinician should be aware that oesophageal submucosal tumours with smooth overlying mucosa may not always be benign; malignancy must be ruled out.

scholarly journals Episodic headache with spontaneous hypothermia reveal Shapiro’s syndrome variant with effectiveness of clonidine therapy

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Mickael Aubignat ◽  
Melissa Tir ◽  
Pierre Krystkowiak ◽  
Daniela Andriuta
Keyword(s):  
Parkinson’S Disease ◽  
Rare Disease ◽  
Rare Case ◽  
Motor Fluctuation ◽  
International Classification ◽  
Headache Disorders ◽  
Case Presentation ◽  
Episodic Headache ◽  
Triggering Factor

Abstract Background Episodic headache with spontaneous hypothermia constitute an uncommon association and is not well recognized in the International Classification of Headache Disorders (ICHD-3). Spontaneous periodic hypothermia, also called Shapiro’s syndrome, is a rare disease characterized by hypothermia attacks associated or not with hyperhidrosis without any triggering factor. Case presentation We report a rare case of Shapiro’s syndrome variantrevealed by episodes of headache with spontaneous hypothermia witheffectiveness of clonidine therapy in a 76-year-old Parkinson’s disease woman. Conclusions In the literature, apart from Shapiro’s syndrome, headache withhypothermia seem to occur very rarely. In our case,these symptoms may be considered as a very rare non-motor fluctuation ofParkinson’s disease.

scholarly journals The largest reported intrathoracic lipoma: a case report and current perspectives review

2019 ◽  
Vol 14 (1) ◽  
Author(s):  
Mohammed Aldahmashi ◽  
Abdalmotaleb Elmadawy ◽  
Mahmoud Mahdy ◽  
Mohamed Alaa
Keyword(s):  
Single Case ◽  
Tumor Resection ◽  
Pathological Examination ◽  
Complete Excision ◽  
Case Presentation ◽  
Medical Checkup ◽  
Excellent Outcome ◽  
The Right ◽  
Intrathoracic Mass

Abstract Background The huge size intrathoracic lipomas are very rare. Few cases have been reported worldwide. To our knowledge, this presented case is one of the few cases reported. Here we report a single case as very huge intrathoracic lipoma compressing the right lung and displacing the diaphragm and liver downward. It has been managed by right posterolateral thoracotomy and complete excision, with excellent outcome. Case presentation A 32-year-old male presented with a symptomatic right intrathoracic mass, which was confirmed to be a lipomatous tumor using computed tomography. A penduculated tumor originating from the mediastinal pleura was resected through the conventional right posterior thoracotomy. Pathological examination indicated a diagnosis of fibrolipoma. Conclusion The tumor was symptomatic and relatively huge when detected during a medical checkup. This enabled the successful tumor resection via conventional thoracotomy approach. Although intrathoracic lipomas are histologically benign, careful observation and follow-up are crucial due to the possibility of recurrence.

scholarly journals Osteosarcoma: A Case Report

2007 ◽  
Vol 01 (01) ◽  
pp. 060-063 ◽  
Author(s):  
Esra Yeşilovaa ◽  
Faruk Akgünlü ◽  
Doğan Dolanmazc ◽  
Füsun Yaşar ◽  
Sevgi Şenere
Keyword(s):  
Case Report ◽  
Head And Neck ◽  
Rare Disease ◽  
Bone Tumor ◽  
Orofacial Pain ◽  
Management Plan ◽  
Malignant Bone Tumor ◽  
Case Presentation ◽  
Diagnosis And Prognosis ◽  
Oral Malignancies

ABSTRACTAlthough osteosarcoma of the head and neck is a relatively rare disease, it is a highly malignant bone tumor. Diagnosis of the tumor is important especially in early stages for improving prognosis. The patients with orofacial pain firstly prefer to go to dentists. Such kind of pain may be associated with an oral or maxillofacial cancer. The dentists must be careful for evaluating the clinical and radiologic clues. These clues determine the biopsy necessity, type and management plan. The aim of this case presentation is to emphasize the importance of dentists on diagnosis and prognosis of oral malignancies. (Eur J Dent 2007;1:60-63)

scholarly journals Intrascrotal Abscess,Propionibacterium acnesandStaphylococcus cohniissp.cohnii: A Case Report and Review of the Literature

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Masciovecchio Stefano ◽  
Alessandro Del Rosso ◽  
Pietro Saldutto ◽  
Giuseppe Paradiso Galatioto ◽  
Carlo Vicentini
Keyword(s):  
Blood Culture ◽  
Pathogenic Bacteria ◽  
Propionibacterium Acnes ◽  
Granulomatous Inflammation ◽  
Pathological Examination ◽  
Review Of The Literature ◽  
Case Presentation ◽  
Scrotal Ultrasound ◽  
Staphylococcus Cohnii ◽  
Systemic Infections

Introduction. ThePropionibacterium acnesand theStaphylococcus cohnii ssp.cohniiare occasional pathogenic bacteria. The intrascrotal localization of thePropionibacterium acnesis exceptional. TheStaphylococcus cohniissp.cohniiis not able to colonize the urogenital apparatus but it is the most frequently responsible for blood culture contamination even if it can sustain, in particular conditions, systemic infections.Case Presentation. We report the case of a 72-year-old man who is under observation for pain and swelling of the left hemiscrotum associated to high fever. The scrotal ultrasound shows the presence of a left intra-scrotal abscess with didymus, epididymis, and intact didymus-epididymis tunicae. The blood culture executed for evening fever during antibiotic therapy has underlined an infection withPropionibacterium acnes. A following blood culture has shown an increase inStaphylococcus cohniissp.cohnii. Due to fever the patient has undergone left orchifunicolectomy with inguino-scrotal toilet. The anatomical pathological examination has also shown the presence of nonspecific granulomatous inflammation compatible withPropionibacterium acnesinfection.Conclusion. The onset of an intrascrotal abscess likely sustained byPropionibacterium acnescomplicated by a possible systemicStaphylococcus cohniissp.cohniisuprainfection is an exceptional event that, in our case, has been resolved with surgical toilet.

Otogenic tetanus: Case presentation

1979 ◽  
Vol 93 (12) ◽  
pp. 1235-1236 ◽  
Author(s):  
R. L. Blair ◽  
D. Hussarau
Keyword(s):  
North America ◽  
Rare Disease ◽  
Operative Treatment ◽  
Early Years ◽  
Primary Immunization ◽  
Radical Mastoidectomy ◽  
Case Presentation ◽  
Tropical Regions ◽  
Ear Injury ◽  
Immunization Programmes

AbstractTetanus resulting from ear injury is extremely rare. However, the otologist should be aware that it does occur. A case of otogenic tetanus recently treated by the authors is presented.In Western countries tetanus in now a rare disease because of extensive immunization programmes. Otogenic tetanus is extremely uncommon in North America, but occurs more frequently in tropical regions (De and De, 1970).Less than forty new cases of tetanus are seen in the Province of Ontario (population, 8·4 million) each year (Department of Statistics, Government of Ontario).It has been stated that the operative treatment of otogenic tetanus should include radical mastoidectomy (Black and Atkins, 1972). This is probably true in severe cases but milder cases do not require this form of therapy.Most children in Canada receive primary immunization with Diphtheria, Tetanus and Pertussis vaccine (DTP) in the early years of life. However, especially in large urban centres, there is a large non-immunized or partially immunized immigrant population.Tetanus occurring in such an immigrant is described.

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