Ovarian non-gestational choriocarcinoma: a case report and review of current literature
Abstract Background: Non-gestational ovarian choriocarcinoma is an extremely rare malignant tumor without established treatment. Because of the rarity of Non-gestational ovarian choriocarcinoma, limited information is available in the literature.Thus, we presented our case and reviewed other cases concerningtheir clinical characteristics, diagnosis, therapeutic effects, and prognoses using the PubMed database.Case presentation: We present a rare case of a patient with Non-gestational ovarian choriocarcinoma with a dysgerminoma. Moreover, we performed a subsequent literature review.An 11-year-old Chinese girl presented with pain persisting for 20 days and a lump in her lower abdomen. Exploratory laparotomy was performed, and postoperative pathological sampling revealed a mixed germ-cell tumor comprising choriocarcinoma and dysgerminoma. Following six cycles of bleomycin, etoposide, and cisplatin, the patient remained recurrence-free after16 months from surgery.Conclusions: The analysis of our and previously reported cases indicated that fertility-sparing surgery combined with postoperative chemotherapy might be beneficial for Non-gestational ovarian choriocarcinoma treatment in adolescent and young female individuals. Longer follow-up periods and further management data are necessary.