scholarly journals Nicotinamide-functionalized carbon quantum dot as new sensing platform for portable quantification of vitamin B12 in fluorescence, UV-Vis and smartphone triple mode

2021 ◽  
Author(s):  
Sahar Dadkhah ◽  
Ali Mehdinia ◽  
Ali Jabbari ◽  
Ahmad Manbohi
Keyword(s):  
Quantum Dot ◽  
Vitamin B12 ◽  
Simultaneous Detection ◽  
High Sensitivity ◽  
Colorimetric Sensing ◽  
Practical Applications ◽  
Carbon Quantum Dot ◽  
Sensing Platform ◽  
Triple Mode

Abstract Development of an efficient, portable and simple nanosensor-based systems with reliable analytical performance for on-site monitoring of vitamin B12 (VB12) are still major problems and a challenging work for quality control of manufacturers. Herein, a new fluorescence, UV-Vis and smartphone triple mode nanosensors were designed for the simultaneous detection of VB12 with high sensitivity and accuracy. A novel nanosensor was synthesized through nicotinamide-functionalizing on carbon quantum dot (NA-CQDs) by an one-step microwave-assisted method with green approaches. The NA-CQDs as new nanosensor showed excellent fluorescence properties and wide linear ranges from 0.1–60 µM with the detection limits of 31.7 nM. Moreover, color changes of NA-CQDs induced by the VB12 could also be detected by UV-Vis spectrophotometer and inhouse-developed application installed on smartphone as a signal reader, simultanusly. The Red, Green and Blue (RGB) intensities of the colorimetric images of NA-CQDs/VB12 system which taken by smartphone's camera converted into quantitative values by the introduced application. A smartphone-integrated with NA-CQDs as colorimetric sensing platform displays good linear ranges (4.16 to 66.6 µM) for on-site determination of VB12 with detection limit of 1.40 µM. The method was successfully applied in the determination of VB12 in complex pharmaceutical supplement formulations without any sample pre-treatment and matrix interfering effects. The recovery results (96.52–105.10%) which are in agreement with the reference methods, demonstrating the capability of the smartphone-assisted colorimetric sensing platform in many on-site practical applications of quality controls.

scholarly journals Colorimetric detection of individual biothiols by tailor made reactions with silver nanoprisms

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Pei Li ◽  
Sang Mo Lee ◽  
Hyo Yong Kim ◽  
Soohyun Kim ◽  
Steve Park ◽  
...  
Keyword(s):  
Human Serum ◽  
Colorimetric Detection ◽  
Chloride Ion ◽  
High Sensitivity ◽  
Cost Effective ◽  
Colorimetric Sensing ◽  
Practical Applications ◽  
Silver Nanoprisms ◽  
Sensing Platform ◽  
Sensitivity And Selectivity

AbstractWe herein described a rapid, sensitive, and selective colorimetric sensing platform for biothiols in human serum, which relies on the dual functions of biothiols as anti-etching and aggregating agent for silver nanoprisms (AgNPRs). In principle, the target biothiols that bind to the surface of AgNPRs through Ag–S covalent interactions protect the AgNPRs from being etched by chloride ion (Cl−) in human serum, thus exhibiting the blue/purple color that is indicative of AgNPRs. On the other hand, the color of AgNPRs turned to yellow in the absence of biothiols or the presence of non-sulfur-containing amino acids, indicating the formation of small silver nanoparticles (AgNPs). Importantly, we found that individual biothiols (Hcy, Cys, and GSH) exert not only the anti-etching effect, but also the aggregating effect on AgNPRs, which can be modulated by simply tuning the pH conditions, and this consequently allows for the discriminative detection of each biothiol. Based on this simple and cost-effective strategy, we successfully determined the Hcy, Cys, and GSH in human serum with high sensitivity and selectivity within 10 min, demonstrating the diagnostic capability and potential in practical applications.

High-activity Mo, S co-doped carbon quantum dot nanozyme-based cascade colorimetric biosensor for sensitive detection of cholesterol

2019 ◽  
Vol 7 (44) ◽  
pp. 7042-7051 ◽  
Author(s):  
Lianjing Zhao ◽  
Zepei Wu ◽  
Guannan Liu ◽  
Huiying Lu ◽  
Yuan Gao ◽  
...  
Keyword(s):  
Quantum Dot ◽  
High Activity ◽  
Sensitive Detection ◽  
Colorimetric Sensing ◽  
Carbon Quantum Dot ◽  
Sensing Platform ◽  
Co Doped

A Mo, S co-doped carbon quantum dot nanozyme-based cascade colorimetric sensing platform was fabricated and its application for detection of cholesterol was shown.

Determination of L-ascorbic Acid by Carbon Quantum Dot/Eosin Y Ratiometric Fluorescence Probe

2020 ◽  
Vol 41 (3) ◽  
pp. 331-338
Author(s):  
武文波 WU Wen-bo ◽  
张越诚 ZHANG Yue-cheng ◽  
李承佳 LI Cheng-jia ◽  
马红燕 MA Hong-yan ◽  
杨晓军 YANG Xiao-jun
Keyword(s):  
Ascorbic Acid ◽  
Quantum Dot ◽  
Fluorescence Probe ◽  
Eosin Y ◽  
Ratiometric Fluorescence ◽  
Carbon Quantum Dot

scholarly journals Colorimetric Nanoplasmonics to Spot Hyperglycemia From Saliva

2020 ◽  
Vol 8 ◽  
Author(s):  
Paolo Donati ◽  
Tania Pomili ◽  
Luca Boselli ◽  
Pier P. Pompa
Keyword(s):  
Large Scale ◽  
Point Of Care ◽  
High Sensitivity ◽  
Diabetic Patients ◽  
Visual Response ◽  
Colorimetric Sensing ◽  
Chronic Patients ◽  
Self Monitoring ◽  
Sensing Platform ◽  
Signal Color

Early diagnostics and point-of-care (POC) devices can save people’s lives or drastically improve their quality. In particular, millions of diabetic patients worldwide benefit from POC devices for frequent self-monitoring of blood glucose. Yet, this still involves invasive sampling processes, which are quite discomforting for frequent measurements, or implantable devices dedicated to selected chronic patients, thus precluding large-scale monitoring of the globally increasing diabetic disorders. Here, we report a non-invasive colorimetric sensing platform to identify hyperglycemia from saliva. We designed plasmonic multibranched gold nanostructures, able to rapidly change their shape and color (naked-eye detection) in the presence of hyperglycemic conditions. This “reshaping approach” provides a fast visual response and high sensitivity, overcoming common detection issues related to signal (color intensity) losses and bio-matrix interferences. Notably, optimal performances of the assay were achieved in real biological samples, where the biomolecular environment was found to play a key role. Finally, we developed a dipstick prototype as a rapid home-testing kit.

Fabrication of a highly sensitive electrochemiluminescence chlorpromazine sensor using a Ru(bpy)32+ incorporated carbon quantum dot–gelatin composite film

2017 ◽  
Vol 9 (6) ◽  
pp. 1011-1017 ◽  
Author(s):  
Zhimin Liu ◽  
Fang Zhang ◽  
Lin Cui ◽  
Kang Wang ◽  
Haijun Zhan
Keyword(s):  
Quantum Dots ◽  
Quantum Dot ◽  
Composite Film ◽  
Carbon Quantum Dots ◽  
Sensitive Detection ◽  
Carbon Quantum Dot ◽  
Sensing Platform ◽  
Highly Sensitive

A novel electrochemiluminescence sensing platform for the sensitive detection of chlorpromazine (CPZ) was fabricated based on a Ru(bpy)32+/carbon quantum dots/gelatin composite film.

A sensitive enzyme-free lactic acid sensor based on NiO nanoparticles for practical applications

2019 ◽  
Vol 11 (28) ◽  
pp. 3578-3583 ◽  
Author(s):  
Sidra Amin ◽  
Aneela Tahira ◽  
Amber Solangi ◽  
Raffaello Mazzaro ◽  
Zafar Hussain Ibupoto ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Glassy Carbon ◽  
Electrochemical Sensing ◽  
Carbon Electrode ◽  
Nio Nanoparticles ◽  
Modified Glassy Carbon Electrode ◽  
Practical Applications ◽  
Sensing Platform ◽  
First Time

A facile and efficient electrochemical sensing platform has been successfully exploited for the first time for the determination of lactic acid using a nickel oxide (NiO) nanoparticle-modified glassy carbon electrode (GCE).

Detection of glutathione with an “off–on” fluorescent biosensor based on N-acetyl-l-cysteine capped CdTe quantum dots

The Analyst ◽  
2015 ◽  
Vol 140 (19) ◽  
pp. 6748-6757 ◽  
Author(s):  
Xuanping Tan ◽  
Jidong Yang ◽  
Qin Li ◽  
Qiong Yang
Keyword(s):  
Quantum Dots ◽  
Quantum Dot ◽  
High Sensitivity ◽  
Cdte Quantum Dots ◽  
Fluorescent Biosensor

This paper reports a quantum dot (QD)-based “off–on” fluorescent biosensor specifically for the determination of glutathione (GSH) with high sensitivity.

scholarly journals Green preparation of nitrogen doped carbon quantum dot films as fluorescent probes

RSC Advances ◽  
2017 ◽  
Vol 7 (88) ◽  
pp. 56087-56092 ◽  
Author(s):  
Yanfei He ◽  
Lina Liang ◽  
Qinghao Liu ◽  
Jinchun Guo ◽  
Dong Liang ◽  
...  
Keyword(s):  
Carbon Source ◽  
Quantum Dot ◽  
Nitrogen Source ◽  
Fluorescence Intensity ◽  
Fluorescent Probes ◽  
High Sensitivity ◽  
Nitrogen Doped ◽  
Carbon Quantum Dot ◽  
Sensitivity And Selectivity ◽  
Nitrogen Doped Carbon

A facile and economical hydrothermal method was developed for the preparation of highly luminescent NCDs by using cabbage juice as carbon source and PP as nitrogen source. The fluorescence intensity of CA-NCDs was quenched by Fe3+ with high sensitivity and selectivity.

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