Assessment of Sagittal Spinopelvic Alignment in Asymptomatic Chinese Juveniles and Adolescents: a Large Cohort Study and Comparative Meta-analysis
Abstract Study design: Retrospective study and comparative meta-analysisObjective: To document the sagittal spinopelvic alignment in a large cohort study in asymptomatic Chinese juveniles and adolescents, and to explore whether these parameters were different from various regions using meta-analysis. Methods: Medical records of 656 asymptomatic Chinese juveniles and adolescents were reviewed. Demographic and lateral radiological parameters were evaluated. Furthermore, a systematic online search was performed to identify eligible studies. Weight mean difference (WMD) with 95% confidence interval (CI) were used to evaluate whether these sagittal parameters were different from various regions. Results: The mean value of sagittal spinopelvic alignment in this study was calculated and analyzed respectively. A total of 18 studies were recruited for meta-analysis. For juvenile populations, TK, PI and SS of non-East Asian were significantly larger than those of Chinese. As for adolescent populations, PI of non-East Asian was found to be greater when compared with that of Chinese; TK and SS of non-East Asian adolescents was significantly greater than those reported in our study as well. All in all, TK, PI and SS in Chinese pre-adult populations were significantly smaller than those populations in non-East Asian regions.Conclusion: Our study was the first large-scale study that reported the mean values of sagittal parameters in asymptomatic Chinese juveniles and adolescents. There were significant differences in TK, PI and SS between Chinese and other previous reported populations, which reminded us for using specific mean values in different populations when restoring a relatively normal sagittal spinopelvic balance in spinal deformity.