Quantitative CT Comparison between COVID-19 and Mycoplasma Pneumonia Suspected as COVID-19: A Longitudinal Study

Abstract Objective: The purpose of this study was to compare imaging features between COVID-19 and mycoplasma pneumonia (MP).Materials and Methods: The data of patients with mild COVID-19 and MP who underwent chest computed tomography (CT) examination from February 1, 2020 to April 17, 2020 were retrospectively analyzed. The Pneumonia-CT-LKM-PP model based on a deep learning algorithm was used to automatically quantify the number, volume, and involved lobes of pulmonary lesions, and longitudinal changes in quantitative parameters were assessed in three CT follow-ups.Results: A total of 10 patients with mild COVID-19 and 13 patients with MP were included in this study. There was no difference in lymphocyte counts at baseline between the two groups (1.43±0.45 vs 1.44±0.50, p=0.279). C-reactive protein levels were significantly higher in MP group than in COVID-19 group (p<0.05). The number, volume, and involved lobes of pulmonary lesions reached a peak in 7-14 days in the COVID-19 group, but there was no peak or declining trend over time in the MP group (p<0.05).Conclusion: Based on the longitudinal changes of quantitative CT, pulmonary lesions peaked at 7-14 days in patients with COVID-19, and this may be useful to distinguish COVID-19 from MP and evaluate curative effects and prognosis.

Download Full-text

ASSOCIATIONS BETWEEN C-REACTIVE PROTEIN LEVELS AND LONGITUDINAL CHANGES IN UROLOGIC MEASURES

The Journal of Urology ◽

10.1016/s0022-5347(08)60093-2 ◽

2008 ◽

Vol 179 (4S) ◽

pp. 30-30 ◽

Cited By ~ 4

Author(s):

Jennifer L St Sauver ◽

Aruna V Sarma ◽

Debra J Jacobson ◽

Michaela E McGree ◽

Michael M Lieber ◽

...

Keyword(s):

C Reactive Protein ◽

Longitudinal Changes ◽

Protein Levels ◽

Reactive Protein

Download Full-text

LONGITUDINAL CHANGES IN PHYSICAL ACTIVITY LEVELS POSITIVELY IMPACT HIGH SENSITIVITY C-REACTIVE PROTEIN LEVELS

Journal of the American College of Cardiology ◽

10.1016/s0735-1097(18)32340-4 ◽

2018 ◽

Vol 71 (11) ◽

pp. A1799

Author(s):

Marcio Sommer Bittencourt ◽

Romulo A. Fernandes ◽

Raphel M. Ritt-Dias ◽

Babu Balagopal ◽

Raquel Conceicao ◽

...

Keyword(s):

Physical Activity ◽

High Sensitivity ◽

Activity Levels ◽

C Reactive Protein ◽

Longitudinal Changes ◽

Protein Levels ◽

Reactive Protein ◽

Physical Activity Levels

Download Full-text

Positive correlation between neovascularization degree of carotid atherosclerosis determined by contrast-enhanced ultrasound and level of serum C-reactive protein

VASA ◽

10.1024/0301-1526/a000429 ◽

2015 ◽

Vol 44 (3) ◽

pp. 0187-0194 ◽

Cited By ~ 6

Author(s):

Xiaoni Chang ◽

Jun Feng ◽

Litao Ruan ◽

Jing Shang ◽

Yanqiu Yang ◽

...

Keyword(s):

Contrast Enhancement ◽

Rank Correlation ◽

Artery Stenosis ◽

Contrast Enhanced Ultrasound ◽

C Reactive Protein ◽

Protein Levels ◽

Reactive Protein ◽

Contrast Enhanced ◽

Grade 3 ◽

Axis View

Background: Neovascularization is one of the most important risk factors for unstable plaque. This study was designed to correlate plaque thickness, artery stenosis and levels of serum C-reactive protein with the degree of intraplaque enhancement determined by contrast-enhanced ultrasound. Patients and methods: Contrast-enhanced ultrasound was performed on 72 carotid atherosclerotic plaques in 48 patients. Contrast enhancement within the plaque was categorized as grade 1, 2 or 3. Maximum plaque thickness was measured in short-axis view. Carotid artery stenosis was categorized as mild, moderate or severe. Results: Plaque contrast enhancement was not associated with the degree of artery stenosis or with plaque thickness. Serum C-reactive protein levels were positively correlated with the number of new vessels in the plaque. C-reactive protein levels increased in the three groups(Grade 1: 3.72±1.79mg/L; Grade 2: 7.88±4.24 mg/L; Grade 3: 11.02±3.52 mg/L), with significant differences among them (F=10.14, P<0.01), and significant differences between each two groups (P<0.05). Spearmans rank correlation analysis showed that serum C-reactive protein levels were positively correlated with the degree of carotid plaque enhancement (Rs =0.69, P<0.01). Conclusions: The combination of C-reactive protein levels and intraplaque neovascularization detected by contrast-enhanced ultrasound may allow more accurate evaluation of plaque stability.

Download Full-text