Diabetes, Employment and Behavioural Risk Factors in China: Marginal Structural Models Versus Fixed Effects Models

This study explores women’s attrition from male-dominated workplaces based on Norwegian public administrative records, covering individuals born 1945–1983, in the period between 2003 and 2013. It examines sex differences in rates of attrition and tests the significance of two commonly proposed explanations in the literature, namely the degree of numerical minority status and motherhood. It also investigates whether these explanations vary by occupational class. Selection into male-dominated workplaces is accounted for by using individual fixed effects models. The results show that attrition rates from male-dominated workplaces are considerably higher among women than among men. Moreover, the risk of female attrition to sex-balanced workplaces increases, regardless of occupational class, with increases in the percentage of males. Childbirth is associated with an increased risk of attrition to female-dominated workplaces, while having young children (⩽ 10 years old) lowered the risk. This association, however, was primarily evident among working-class women in manual occupations.

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Association of UCP1 and UCP2 variants with diabetic retinopathy susceptibility in type-2 diabetes mellitus patients: a meta-analysis

BMC Ophthalmology ◽

10.1186/s12886-021-01838-1 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Xujia Liu ◽

Zehua Jiang ◽

Guihua Zhang ◽

Tsz Kin Ng ◽

Zhenggen Wu

Keyword(s):

Diabetes Mellitus ◽

Diabetic Retinopathy ◽

Fixed Effects ◽

Literature Search ◽

Meta Analysis ◽

Sensitivity Analyses ◽

Fixed Effects Models ◽

Type 2 Dm ◽

Subgroup Analyses

Abstract Background Genetic association of uncoupling proteins (UCPs) variants with the susceptibility of diabetic retinopathy (DR) in diabetes mellitus (DM) patients has been reported but with controversy. Here we aimed to conduct a meta-analysis to confirm the association of different UCPs variants with DR. Methods Three databases (Medline Ovid, Embase Ovid and CENTRAL) were applied in the literature search. Five genetic models, including allelic, homozygous, heterozygous, dominant and recessive models, were evaluated. Odds ratios (OR) were estimated under the random or fixed-effects models. Subgroup analyses, publication bias and sensitivity analyses were also conducted. Results Eleven studies on 2 UCPs variants (UCP1 rs1800592 and UCP2 rs659366) were included. Our meta-analysis showed that UCP1 rs1800592 was not associated with DR in type-2 DM patients, and UCP2 rs659366 also showed no association with DR. In the subgroup analyses on the stage of DR, allele G of UCP1 rs1800592 significantly increased the susceptibility of proliferative diabetic retinopathy (PDR) in type-2 DM patients in the allelic (OR = 1.26, P = 0.03) and homozygous models (OR = 1.60, P = 0.04). Subgroup analysis on ethnicity did not found any significant association of rs1800592 and rs659366 with DR. Conclusion Our meta-analysis confirmed the association of UCP1 rs1800592 variant with PDR in patients with type-2 DM, suggesting its potential as a genetic marker for PDR prediction in population screening.

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Caesarean delivery and early childhood caries: Estimation with marginal structural models in Brazilian pre‐schoolers

Community Dentistry And Oral Epidemiology ◽

10.1111/cdoe.12634 ◽

2021 ◽

Author(s):

Lorena Lúcia Costa Ladeira ◽

Sarah Pereira Martins ◽

Cayara Mattos Costa ◽

Elizabeth Lima Costa ◽

Rubenice Amaral da Silva ◽

...

Keyword(s):

Early Childhood ◽

Caesarean Delivery ◽

Early Childhood Caries ◽

Structural Models ◽

Marginal Structural Models ◽

Childhood Caries

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Multiple behavioural risk factors of non-communicable diseases among adolescents in four Caribbean countries: prevalence and correlates

International Journal of Adolescent Medicine and Health ◽

10.1515/ijamh-2021-0021 ◽

2021 ◽

Vol 0 (0) ◽

Author(s):

Supa Pengpid ◽

Karl Peltzer

Keyword(s):

Risk Factors ◽

Parental Support ◽

Fast Food ◽

Vegetable Intake ◽

Communicable Diseases ◽

Cross Sectional ◽

Non Communicable Diseases ◽

Behavioural Risk Factors ◽

Fast Food Consumption ◽

High Prevalence

Abstract Objectives The study assessed the prevalence and associated factors of behavioural risk factors of non-communicable diseases (NCDs) among adolescents in four Caribbean countries. Content In all 9,143 adolescents (15 years = median age) participated in the cross-sectional “2016 Dominican Republic, 2016 Suriname, 2017 Jamaica, and 2017 Trinidad and Tobago Global School-Based Student Health Survey (GSHS)”. Eight behavioural risk factors of NCDs were assessed by a self-administered questionnaire. Summary Prevalence of each behavioural NCD risk factor was physical inactivity (84.2%), inadequate fruit and vegetable intake (82.2%), leisure-time sedentary behaviour (49.6%), daily ≥2 soft drinks intake (46.8%), ever drunk (28.6%), twice or more days a week fast food consumption (27.6%), having overweight/obesity (27.4%), and current tobacco use (13.8%). Students had on average 3.6 (SD=1.4), and 79.0% had 3–8 behavioural NCD risk factors. In multivariable linear regression, psychological distress and older age increased the odds, and attending school and parental support decreased the odds of multiple behavioural NCD risk factors. Outlook A high prevalence and co-occurrence of behavioural risk factors of NCDs was discovered and several factors independently contributing to multiple behavioural NCD risk factors were identified.

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