scholarly journals Risk Factors of Deterioration in Quality of Life Scores in Thyroid Cancer Patients After Thyroidectomy

2019 ◽  
Vol Volume 11 ◽  
pp. 10593-10598 ◽  
Author(s):  
Jie Li ◽  
Ling Bo Xue ◽  
Xiao Yi Gong ◽  
Yan Fang Yang ◽  
Bu Yong Zhang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Thyroid Cancer ◽  
Cancer Patients

scholarly journals Quality of Life and Psychological Distress during Cancer: A Prospective Observational Study Involving Liver Cancer Patients

2021 ◽  
pp. 576-585
Author(s):  
Madeeha Malik ◽  
Iqra Parveen Kiyani ◽  
Shazana Rana ◽  
Azhar Hussain ◽  
Muhammad Bin Aslam Zahid
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Liver Cancer ◽  
Medical History ◽  
Cancer Patients ◽  
Study Design ◽  
Negative Impact ◽  
Past Medical History ◽  
Symptom Scale

Introduction: Liver Cancer is aggressive cancer and patients are mostly screened and diagnosed when they become symptomatic at advanced. Disease severity, depression, fatigue, joint pain, and poor appetite have been reported as strong determinants of quality of life (QoL) among liver cancer patients. Aims: The objective of the study was to assess the quality of life and depression among liver cancer patients in Pakistan. Study Design:  A descriptive cross-sectional study design was used. Place and Duration of Study: The study was conducted in healthcare facilities of Islamabad and Rawalpindi, Pakistan between June 2020-December 2020. Methodology: Two pre-validated questionnaires i.e. EORTC QLQ-C30 and HADS were self-administered to a sample of 100 liver cancer patients selected using a convenience sampling technique for measuring QoL and depression, respectively. After data collection, data was cleaned, coded, and entered in SPSS. Results: The results highlighted that the lowest scores observed in the domain of symptom scale were: Nausea and Vomiting (23.72, ± 28.238), Dyspnea (25.27, ± 26.90), Constipation (26.03, ± 34.75) followed by Diarrhea (22.63, ± 28.42), whereas highest scores in the symptom scale were observed in the domain of fatigue (37.69, ± 20.06), pain (40.37, ± 18.44), insomnia (41.65, ± 32.37) and financial difficulties (60.33, ± 33.830). On the other hand, highest score on the functional scale was observed for physical functioning (64, ± 21.76) and the lowest score was observed in social functioning (53.19, ± 20.66). Conclusion: The present study concluded that liver cancer had a negative impact on risk factors/past medical history, co-morbidities, and poor socio-economic of life across all domains along with moderate depression in liver cancer patients. Illiteracy, advanced liver cancer stage, risk factors/past medical history, co-morbidities and poor socio-economic status negatively affected functional and symptom scale. Appropriate health educational and psychological interventional programs targeting patients should be initiated to improve awareness and reduce depression among liver cancer patients.

scholarly journals Predictive factors of posttreatment fracture by definitive radiotherapy for uterine cervical cancer

2020 ◽  
Author(s):  
Kazuki Ishikawa ◽  
Tsuneo Yamashiro ◽  
Takuro Ariga ◽  
Takafumi Toita ◽  
Wataru Kudaka ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Cervical Cancer ◽  
Multivariate Analysis ◽  
Radiation Therapy ◽  
Cancer Patients ◽  
Clinical Characteristics ◽  
Univariate Analysis ◽  
Uterine Cervical Cancer

Abstract Purpose Fractures are known to shorten life expectancy and worsen the quality of life. The risk of fractures after radiation therapy in cervical cancer patients is known to be multifactorial. In this study, we examined risk factors for fractures in cervical cancer patients, especially by evaluating bone densities and DVH parameters for fractured bones. Materials and Methods For 42 patients, clinical characteristics, pretreatment CT bone densities, and radiation dose were compared between patients with and without fractures. Results Posttreatment fractures occurred in 25 bones among ten patients. Pretreatment CT bone densities were significantly lower in patients with fractures (P < 0.05–0.01 across sites, except for the ilium and the ischium). Although DVH parameters were also significantly associated with fractures in univariate analysis, only CT densities were significantly associated with fractures in multivariate analysis. Conclusion Pretreatment CT densities of spinal and pelvic bones, which may reflect osteoporosis, have a significant impact on the risk for posttreatment fractures.

Comparison of four strategies of follow-up in thyroid cancer patients: A cost-utility analysis

2007 ◽  
Vol 25 (18_suppl) ◽  
pp. 6606-6606
Author(s):  
G. de Pouvourville ◽  
I. Borget ◽  
M. Allyn ◽  
M. Schlumberger
Keyword(s):  
Quality Of Life ◽  
Thyroid Cancer ◽  
Diagnostic Accuracy ◽  
Cancer Patients ◽  
Cost Utility ◽  
Cost Utility Analysis ◽  
Whole Body ◽  
Utility Analysis

6606 Background: In thyroid cancer patients, follow-up is designed to detect recurrent disease and consists of neck- ultrasonography (US), thyroglobulin measurement (Tg) and radioiodine whole body scan (WBS). Recent guidelines have restricted the use of WBS to suspicious cases. To insure diagnostic accuracy, follow-up control requires TSH stimulation, either with thyroid hormone withdrawal (THW) or rhTSH, which have demonstrated similar diagnostic accuracy. THW induces significant morbidity associated with hypothyroidism, leading to a decrease in patient quality of life and ability to work, whereas rhTSH is an innovative costly drug that avoids such patient burden. A societal cost-utility analysis was conducted to compare 4 follow-up strategies, combining a method of stimulation (rhTSH or THW) and a testing protocol (US+Tg+WBS or US+Tg alone). Methods: A Markov model was built to describe the follow-up of thyroid cancer patients first treated by thyroidectomy and radioiodine ablation, over 5 years. Estimates for diagnostic accuracy values and recurrence rate were extracted from a French multicenter randomized trial. Costs were computed from the perspective of the society, including medical resources consumed (hospitalisation, rhTSH, tests, treatment of recurrence). The model also incorporated the benefits of rhTSH in terms of quality of life (utility scores derived from SF36) and the reduction in duration and overall cost of sick leave. Results: Among the 753 patients included, 13 patients presented recurrence. rhTSH stimulation resulted in a higher utility score (0.802 vs. 0.637) over the period of stimulation and a reduction of 1083 € of absenteeism costs in active patients. As compared to the THW+Tg+US+WBS strategy, the incremental cost-utility ratios (ICER) showed economic dominance for the rhTSH strategies with ratios of −16,876 and −19,297 €/QALY with and without WBS respectively. The ICER for the strategy THW+US+Tg reached 29,333 €/QALY, as compared to THW+Tg+US+WBS strategy. Conclusions: the recommended strategy combining Tg determination and US after rhTSH stimulation appears the most cost-effective in the follow-up of thyroid cancer patients, as it is the strategy the less costly and associated with improved patient quality of life. No significant financial relationships to disclose.

scholarly journals Persistent quality of life impairments in differentiated thyroid cancer patients: results from a monitoring programme

2015 ◽  
Vol 42 (8) ◽  
pp. 1179-1188 ◽  
Author(s):  
Eva-Maria Gamper ◽  
Lisa M. Wintner ◽  
Margarida Rodrigues ◽  
Sabine Buxbaum ◽  
Bernhard Nilica ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Thyroid Cancer ◽  
Cancer Patients ◽  
Differentiated Thyroid Cancer ◽  
Monitoring Programme

scholarly journals Risk Factors and Quality of Life of Lung Cancer Survivors in Lahore, Pakistan

2021 ◽  
pp. 68-71
Author(s):  
Rehan Ahmad Khan Sherwani ◽  
Sajjad Ali Gill ◽  
Saba Younus ◽  
Sana Saeed ◽  
Nadia Saeed ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Lung Cancer ◽  
Family History ◽  
Cancer Patients ◽  
Environmental History ◽  
Well Being ◽  
Lung Cancer Patients ◽  
History Of

Introduction: The objectives of this study is to determine the risk factors of lung cancer were patients and investigate the quality of life of lung cancer survivors. The occupational, smoking, personal, environmental and family history of the survivors are investigated. The well-being of the survivors with physical and social norms not were also studied. Methods: Risk factors and quality of life from a sample of 50 lung cancer patients investigated through a self-administered questionnaire after getting consent from the hospital management and the patients. All the analysis has been done in SPSS 21. Results: Most of the lung cancer patients were male smokers with a strong history of smoking, and more than half of the respondents inhaled while smoking cigarettes. The significant risk factors among non-smokers are occupational history, personal history, environmental history, and family history. The impact of environmental history with smoking history is observed in lung cancer patients. The physical well-being of the patients is considerably affected by the disease and the pain in their daily activities. Conclusion: Smoking remained the leading risk factor of lung cancer patients followed by radon. However, family history is found statistically significant in the prevalence of lung cancer. Authorities should draw and implement some guiding rules to control smoking, radon, and air pollution, particularly in residential areas.

scholarly journals Prevalence of Sleep Disturbances in Pediatric Cancer Patients and Their Diagnosis and Management

Children ◽  
2021 ◽  
Vol 8 (12) ◽  
pp. 1100
Author(s):  
Irtiza N. Sheikh ◽  
Michael Roth ◽  
Peter L. Stavinoha
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Cancer Patients ◽  
Pediatric Cancer ◽  
Sleep Disturbances ◽  
Negative Impact ◽  
Management Strategies ◽  
Common Source ◽  
Pediatric Cancer Patients

Sleep disturbances represent an understudied yet common source of distress among pediatric cancer patients and survivors, with deleterious effects on quality of life. Sleep issues stem from multiple risk factors, yet individual contributors are difficult to isolate, consequently impeding the identification of targets for intervention. In many pediatric cancer patients, disrupted sleep and its negative impact on quality of life continue into adulthood and may affect various functional domains. This literature review highlights the types and prevalence of sleep disturbances in pediatric cancer patients during active treatment and through survivorship. Potential etiological and risk factors for disturbed sleep are summarized, including the effects of cancer and its treatment, psychosocial and family factors, as well as individual-patient aspects, such as genetics, mood and coping skills. While existing assessment and management strategies are reviewed, the literature is incomplete, and significant gaps emerge in our understanding of sleep disturbances in pediatric cancer patients and survivors. The review concludes with recommendations of areas where further research is needed. The aims of this review include increasing clinicians’ awareness of sleep disturbances as a significant source of poor quality of life in pediatric cancer patients and survivors and directing researchers to gaps in our understanding of sleep disturbances in pediatric cancer patients and survivors.

scholarly journals Health Related Quality of Life of Thyroid Cancer Patients

2020 ◽  
Vol 38 (2) ◽  
pp. 1-8
Author(s):  
AKM Farhad Hossain ◽  
Md Ziaul Islam ◽  
Sayada Fatema Khatun
Keyword(s):  
Quality Of Life ◽  
Thyroid Cancer ◽  
Cancer Patients ◽  
Clinical Condition ◽  
Family Income ◽  
Health Related Quality ◽  
Hrqol Score ◽  
Related Quality ◽  
Health Related

Background: Having the longevity of thyroid cancer patients, any impairment in health-related quality of life (HRQOL) during the follow-up period is of great importance. Objective: The study was conducted to determine the health related quality of life of thyroid cancer patients. Material and methods: This cross sectional study was conducted among 246thyroid cancer patients. Data were collected by face-to-face interview and reviewing medical records with semi-structured questionnaire and checklist with validated scale. The subjects were purposively selected following specific selection criteria and maintaining ethical issues. Place and period of study: The study was conducted during the period from July 2018-June 2019 in two tertiary hospitals of Dhaka city: Bangabandhu Sheikh Mujib Medical University and Dhaka Medical College Hospital, Dhaka. Results: This study revealed that majority (74.4%) of respondents was female, married (72%), housewife (61.4%), rural respondent (41.1%) and had primary education (69%). Mean (± SD) age of the respondent was 37.85(±12.20) years (range 14-70 years) and mean (± SD) monthly family income was Tk.17681(±10602). Out of 246 cases, 204 (82.9%) was papillary and 42 (17.1%) was follicular carcinoma. Main presenting features were neck swelling (91.5%), swollen lymph node (41.9%), dysphonia (57.3%) and dysphagia (35.4%). Mean (± SD) of total HRQOL score was 73.7 ± 8.39. HRQOL score of students and higher educated patients were better among the respective groups (p <.001). The study showed the association of HRQOL with clinical condition of thyroid cancer patients (R2=.025). HRQOL revealed the strong prediction with education (β=-0.888, p<.05), family income (β=0.05, p<.05), marital status (β=-0.1.384, p<.05), clinical condition (β=-0.522, p<.05) and perceived stress (β=-0.632, p<.001). Conclusion: The overall HRQOL score was considerably good in this study. Timely detection, regular motivation and attending clinical condition may significantly improve the HRQOL of thyroid cancer patients JOPSOM 2019; 38(2): 1-8

scholarly journals Comparing Symptom Burden and Quality of Life after Partial Thyroidectomy vs Total Thyroidectomy in Thyroid Cancer Patients

2021 ◽  
Vol 233 (5) ◽  
pp. S66
Author(s):  
Mariam N. Ali-Mucheru ◽  
Sarah E. Robbins ◽  
Cameron L. Macdonald ◽  
Nadine P. Connor ◽  
Rebecca S. Sippel
Keyword(s):  
Quality Of Life ◽  
Thyroid Cancer ◽  
Total Thyroidectomy ◽  
Cancer Patients ◽  
Symptom Burden ◽  
Partial Thyroidectomy

scholarly journals Risk Factors for Decreased Quality of Life in Thyroid Cancer Survivors: Initial Findings from the North American Thyroid Cancer Survivorship Study

Thyroid ◽  
2015 ◽  
Vol 25 (12) ◽  
pp. 1313-1321 ◽  
Author(s):  
Briseis Aschebrook-Kilfoy ◽  
Benjamin James ◽  
Sapna Nagar ◽  
Sharone Kaplan ◽  
Vanessa Seng ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
Thyroid Cancer ◽  
Cancer Survivors ◽  
Cancer Survivorship ◽  
North American ◽  
The North
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