scholarly journals Comparison of Lipid Profile, Liver Enzymes, Creatine Kinase and Lactate Dehydrogenase Among Type II Diabetes Mellitus Patients on Statin Therapy

2020 ◽  
Vol Volume 13 ◽  
pp. 763-773
Author(s):  
Mezgebu Legesse Habte ◽  
Daniel Seifu Melka ◽  
Maria Degef ◽  
MKC Menon ◽  
Helen Yifter ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Creatine Kinase ◽  
Lactate Dehydrogenase ◽  
Lipid Profile ◽  
Statin Therapy ◽  
Type Ii Diabetes ◽  
Liver Enzymes ◽  
Type Ii Diabetes Mellitus ◽  
Type Ii

scholarly journals MICROALBUMINEMIA;

2017 ◽  
Vol 24 (03) ◽  
pp. 478-481
Author(s):  
Muhammad Mahboob Alam ◽  
Muhammad Akhtar Parvez ◽  
Muhammad Murtaza
Keyword(s):  
Diabetes Mellitus ◽  
Lipid Profile ◽  
Type Ii Diabetes ◽  
Type Ii Diabetes Mellitus ◽  
Diabetic Patients ◽  
Type Ii

Objective: to determine the frequency of microalbuminemia in type IIdiabetic patients and to compare lipid profile in type II diabetic patients with and withoutmicroalbuminuria. Settings: Department of Medicine, Allied Hospital, Faisalabad. Durationof study: From: January 2015 to December 2015. Results: In our study, mean age was53.18+9.32 years, 43.90% (n=151) were male and 56.10% (n=193) were females, frequencyof microalbuminuria in type II diabetes mellitus was recorded in 32.56%(n=112). Conclusion:the frequency of microalbuminemia in type II diabetic patients is higher while the frequencyof hypertriglyceridemias, increased LDL-C and decreased HDL-C in Type II diabetic patientsis significantly higher in patients with microalbuminuria when compared them withoutmicroalbuminuria..

A Study of Fasting and Postprandial Lipid Profile in Patients with Type II Diabetes Mellitus

2019 ◽  
Vol 10 (2) ◽  
pp. 59-61
Author(s):  
Nilima Deshpande ◽  
◽  
Gajanan Halkanche ◽  
Vishal Patil ◽  
Rajaram Power ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Lipid Profile ◽  
Type Ii Diabetes ◽  
Type Ii Diabetes Mellitus ◽  
Type Ii ◽  
Postprandial Lipid

Trace Element and Lipid Profile in Patients with Type-II Diabetes Mellitus

2020 ◽  
Vol 6 (2) ◽  
pp. 59
Author(s):  
Abdullah Arpaci ◽  
Hasret Ecevit ◽  
Muhittin Onderci ◽  
Meral Kucuk ◽  
Serdar Olt
Keyword(s):  
Diabetes Mellitus ◽  
Lipid Profile ◽  
Trace Element ◽  
Type Ii Diabetes ◽  
Type Ii Diabetes Mellitus ◽  
Type Ii

scholarly journals Role of Apo B and Apo A1 Levels in Relation to Conventional Lipid Profile in Patients of Ischaemic Heart Disease with or without Type II Diabetes Mellitus

2021 ◽  
Author(s):  
Hardik N Javia ◽  
Milav H Bhavsar ◽  
Bhavesh R Sadariya ◽  
Amitkumar V Maheshwari ◽  
Hariom Sharma
Keyword(s):  
Diabetes Mellitus ◽  
Lipid Profile ◽  
Type Ii Diabetes ◽  
Type Ii Diabetes Mellitus ◽  
P Value ◽  
Type Ii ◽  
Apo B ◽  
Group Iii ◽  
Group I ◽  
Group Ii

Introduction: Ischaemic Heart Disease (IHD) or Coronary Artery Disease (CAD) is the most prevalent chronic disease and the main leading cause of death in the world, with more than half a million newly diagnosed IHD patients each year. Central to this are disorders of lipoprotein metabolism. Apolipoprotein B (Apo B) and Apolipoprotein A1 (Apo A1) are structural and functional components of lipoprotein particles that serve as transporters of cholesterol. Apo B and Apo A1 are among the emerging markers for Cardiovascular Diseases (CVD). Routine conventional lipid profile does not incorporate these markers. Aim: To determine the level of Apo A1 and Apo B in patients of IHD with or without Type II Diabetes Mellitus (T2DM) and analyse the significance of these parameters over the conventional lipid profile. Materials and Methods: The case-control study was conducted at Government Medical College, Bhavnagar, Gujarat, India from July 2013 to December 2013. The study consists of 100 participants including 50 having IHD only (Group I), 50 having IHD with T2DM (Group II) as study groups and 50 healthy individuals (Group III) as control. Various biochemical parameters including Apo B and Apo A1 were analysed and statistically evaluated to come to conclusion. Results: The demographic details of the participants which shows no significant different in age and gender among groups I, II and III. Apo B and A1 were elevated in group I and II and were found highly significant (p-value <0.0001) as compared to the group III. There was positive correlation of serum Apo B levels with total cholesterol (r=0.495, p-value <0.0001), Low-Density Lipoproteins (LDL-C) (r=0.526, p-value <0.0001) and Apo A1 (r=0.685, p-value <0.0001) in group I and LDL-C (r=0.468, p-value=0.001) and Apo A1 (r=0.754, p-value <0.0001) in group II. Similarly, Apo A1 levels were positively correlated with Apo B (r=0.685, p<0.0001) in group I and LDL-C (r=0.305, p-value=0.031) and Apo B (r=0.754, p-value <0.0001) in group II. Conclusion: As the Apo B and Apo A1 cover both atherogenic and antiatherogenic lipid parameters respectively, it can be used as a better predictor of development of IHD with and without T2DM in comparison to conventional parameters of lipid profile.

scholarly journals Association of fetuin-A with dyslipidemia and insulin resistance in type-II Diabetics of Pakistani population

2019 ◽  
Vol 36 (2) ◽  
Author(s):  
Fasiha Fatima ◽  
Naveed Ahsan ◽  
Aliya Nasim ◽  
Faiza Alam
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Lipid Profile ◽  
Type Ii Diabetes ◽  
Type Ii Diabetes Mellitus ◽  
Type Ii ◽  
Pakistani Population ◽  
Fetuin A ◽  
Significant Difference ◽  
Type Ii Diabetics

Background & Objective: Fetuin-A, hepatokine is responsible for instigating insulin resistance by inhibiting tyrosine kinase receptors. Our objective was to investigate the relationship of fetuin-A with dyslipidemia and insulin resistance in type-II diabetics of Pakistani population. Methods: In this cross sectional study which was conducted at Basic Medical Sciences Institute, Jinnah Postgraduate Medical Centre, Karachi between October 2013 to March 2014, a total of 330 participants were selected and divided into two groups. Group-A (n = 165) normal healthy individual and Group-B (n = 165) Type-II diabetes mellitus mellitus with no comorbidities. Serum fetuin-A and insulin levels were determined by commercially prepared ELISA kits while fasting blood glucose (FBG) and lipid profile were performed by enzymatic kit method. Employing independent t-test, comparison of groups was done and correlation was achieved by using spearman correlation. Results: The results demonstrate a significant difference in mean values of fetuin-A, lipid profile, glucose, insulin and Homoeostasis Model Assessment of Insulin resistance (HOMA-IR) in type-II diabetics when compared to normal healthy individuals (p<0.01). A positive correlation was found between serum fetuin-A levels and FBG(r= 0.495, p< 0.001), insulin(r= 0.227, p< 0.001), HOMA-IR(r= 0.336, p<0.001, triglycerides(r= 0.197, p< 0.001) and LDL-cholesterol(r= 0.170, p= 0.002), while negative correlation with HDL-cholesterol(r= -0.251, p< 0.001). Conclusion: The study concludes that fetuin-A might be accountable for dyslipidemia and insulin resistance in type-II diabetes mellitus mellitus. So the high levels of Fetuin-A responsible for insulin resistance might alters endothelium and causes inflammation, vasoconstriction and thrombosis and ultimately atherosclerosis. doi: https://doi.org/10.12669/pjms.36.2.1106 How to cite this:Fatima F, Ahsan N, Nasim A, Alam F. Association of fetuin-A with dyslipidemia and insulin resistance in type-II Diabetics of Pakistani population. Pak J Med Sci. 2020;36(2):---------. doi: https://doi.org/10.12669/pjms.36.2.1106 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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